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The map label for this gene is yrkH [H]

Identifier: 222094526

GI number: 222094526

Start: 849381

End: 850511

Strand: Direct

Name: yrkH [H]

Synonym: BCQ_0864

Alternate gene names: 222094526

Gene position: 849381-850511 (Clockwise)

Preceding gene: 222094525

Following gene: 222094527

Centisome position: 16.29

GC content: 35.72

Gene sequence:

>1131_bases
ATGAGTGTTAAATCATTACAAGCAAAAGATGTTGCAGAGAAAGTTTTATTCGGAGAGTTGTTTATTTTAGATGTTCGTAA
TGAGACGGATTATGAAGATTGGAAAATTGAAGGGAAACAAATCTCATCTATAAATAAACCGTATTTTGATTTGTTAGATG
GTGTAGATCATATTGTAAGTGAATTACCTAAAGATAAAGATGTTTTAGTAGTATGCGCAAAAGAAGGGTCTTCTATATTT
GTGGCAGAGCAATTAACAGAGGCTGGATTAGAAAATATTTATTATTTAGCTGGTGGTATGAAGGCATGGAGTGAATATGT
AAAGCCTGTAAAAGTTGGAGATTTAAAAAATGGCGGAAGTATGTATCAGTTTAACCGTCTTGGAAAAGGCTGTTTATCTT
ATATGGTCGTTTCAAACGGTGAAGCAGCAGTTATTGATGCAGTAAGAACAGTTGAAGCGTATGAAGAATTTGCGAAAGAG
CATGCTGTTACGATTACGAATGTAATGGATACACATTTACATGCAGACCATATTTCTGGAGGACGTAAGTTAGCGGAAAA
AGTAGGTGGTACGTATTGGTTACCGCCAAAAGATGCGGAGGAAGTTGTTTTCTCATACGAACCGCTTGTTGAAGGATCTG
TTATTACGGTGGGGGGTACTAAAATTGAAATTGACGCATTATACTCACCAGGGCATACGATTGGAAGTACGTCATTTATT
GTAGATGATTCCTATTTATTATCAGGCGATATTTTATTTGTAGATTCAATCGGGCGTCCAGATCTTGCTGGGAAAGCTGA
AGATTGGGTAAGTGATTTACGTAATACTTTGTATAGCCGATATAAAGAACTATCTCAAAGTTTAATTGTGTTACCGGCTC
ATTATTCAAAAATAAGTGAAATGGACGAAAGTGGTATTGTTAGTGCAAAATTAAAAGATTTATTTGAGCATAATGCAGGT
TTAAATATTGAGGATGAGGGAGAGTTCCGTAAAGTTGTAACAGAGAATTTACCACCTCAACCGAATGCATATCAAGAAAT
TCGTCAAACAAATATGGGACAATTAAATCCAAATGAAGACGAAGAGCGTGAAATGGAGATTGGTCCAAACCGTTGTGCTG
TTCATAATTAA

Upstream 100 bases:

>100_bases
ATGAAAATGTGAAAAATGTCATTCCAGGTATGTTAGAGTGGCAAGGGAATATAAAGAATTAAATTTTTTTAAATGTAAAT
ATACCATAGGGGGTAAAAAG

Downstream 100 bases:

>100_bases
TTCGGTTTCAAATGAAATAAACACAGGAGGTATATGAAATGAATGCCAAGCAAGTATTAGATGTAAAAGGATTAGCGTGT
CCAATGCCAATTGTAAAAAC

Product: metallo-beta-lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MSVKSLQAKDVAEKVLFGELFILDVRNETDYEDWKIEGKQISSINKPYFDLLDGVDHIVSELPKDKDVLVVCAKEGSSIF
VAEQLTEAGLENIYYLAGGMKAWSEYVKPVKVGDLKNGGSMYQFNRLGKGCLSYMVVSNGEAAVIDAVRTVEAYEEFAKE
HAVTITNVMDTHLHADHISGGRKLAEKVGGTYWLPPKDAEEVVFSYEPLVEGSVITVGGTKIEIDALYSPGHTIGSTSFI
VDDSYLLSGDILFVDSIGRPDLAGKAEDWVSDLRNTLYSRYKELSQSLIVLPAHYSKISEMDESGIVSAKLKDLFEHNAG
LNIEDEGEFRKVVTENLPPQPNAYQEIRQTNMGQLNPNEDEEREMEIGPNRCAVHN

Sequences:

>Translated_376_residues
MSVKSLQAKDVAEKVLFGELFILDVRNETDYEDWKIEGKQISSINKPYFDLLDGVDHIVSELPKDKDVLVVCAKEGSSIF
VAEQLTEAGLENIYYLAGGMKAWSEYVKPVKVGDLKNGGSMYQFNRLGKGCLSYMVVSNGEAAVIDAVRTVEAYEEFAKE
HAVTITNVMDTHLHADHISGGRKLAEKVGGTYWLPPKDAEEVVFSYEPLVEGSVITVGGTKIEIDALYSPGHTIGSTSFI
VDDSYLLSGDILFVDSIGRPDLAGKAEDWVSDLRNTLYSRYKELSQSLIVLPAHYSKISEMDESGIVSAKLKDLFEHNAG
LNIEDEGEFRKVVTENLPPQPNAYQEIRQTNMGQLNPNEDEEREMEIGPNRCAVHN
>Mature_375_residues
SVKSLQAKDVAEKVLFGELFILDVRNETDYEDWKIEGKQISSINKPYFDLLDGVDHIVSELPKDKDVLVVCAKEGSSIFV
AEQLTEAGLENIYYLAGGMKAWSEYVKPVKVGDLKNGGSMYQFNRLGKGCLSYMVVSNGEAAVIDAVRTVEAYEEFAKEH
AVTITNVMDTHLHADHISGGRKLAEKVGGTYWLPPKDAEEVVFSYEPLVEGSVITVGGTKIEIDALYSPGHTIGSTSFIV
DDSYLLSGDILFVDSIGRPDLAGKAEDWVSDLRNTLYSRYKELSQSLIVLPAHYSKISEMDESGIVSAKLKDLFEHNAGL
NIEDEGEFRKVVTENLPPQPNAYQEIRQTNMGQLNPNEDEEREMEIGPNRCAVHN

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Escherichia coli, GI1787158, Length=173, Percent_Identity=27.7456647398844, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR001763 [H]

Pfam domain/function: PF00753 Lactamase_B; PF00581 Rhodanese [H]

EC number: NA

Molecular weight: Translated: 41709; Mature: 41578

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKSLQAKDVAEKVLFGELFILDVRNETDYEDWKIEGKQISSINKPYFDLLDGVDHIVS
CCCCHHHHHHHHHHHHHCEEEEEEECCCCCCCCEEECCHHHCCCCCCHHHHHHHHHHHHH
ELPKDKDVLVVCAKEGSSIFVAEQLTEAGLENIYYLAGGMKAWSEYVKPVKVGDLKNGGS
HCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHEEEECCCHHHHHHHCCCEEECCCCCCCC
MYQFNRLGKGCLSYMVVSNGEAAVIDAVRTVEAYEEFAKEHAVTITNVMDTHLHADHISG
CHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHCCC
GRKLAEKVGGTYWLPPKDAEEVVFSYEPLVEGSVITVGGTKIEIDALYSPGHTIGSTSFI
HHHHHHHCCCEEECCCCCHHHHHEECCCCCCCCEEEECCCEEEEEEEECCCCCCCCEEEE
VDDSYLLSGDILFVDSIGRPDLAGKAEDWVSDLRNTLYSRYKELSQSLIVLPAHYSKISE
EECCEEEECCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEHHHHHHHH
MDESGIVSAKLKDLFEHNAGLNIEDEGEFRKVVTENLPPQPNAYQEIRQTNMGQLNPNED
CCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCC
EEREMEIGPNRCAVHN
CHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SVKSLQAKDVAEKVLFGELFILDVRNETDYEDWKIEGKQISSINKPYFDLLDGVDHIVS
CCCHHHHHHHHHHHHHCEEEEEEECCCCCCCCEEECCHHHCCCCCCHHHHHHHHHHHHH
ELPKDKDVLVVCAKEGSSIFVAEQLTEAGLENIYYLAGGMKAWSEYVKPVKVGDLKNGGS
HCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHEEEECCCHHHHHHHCCCEEECCCCCCCC
MYQFNRLGKGCLSYMVVSNGEAAVIDAVRTVEAYEEFAKEHAVTITNVMDTHLHADHISG
CHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHCCC
GRKLAEKVGGTYWLPPKDAEEVVFSYEPLVEGSVITVGGTKIEIDALYSPGHTIGSTSFI
HHHHHHHCCCEEECCCCCHHHHHEECCCCCCCCEEEECCCEEEEEEEECCCCCCCCEEEE
VDDSYLLSGDILFVDSIGRPDLAGKAEDWVSDLRNTLYSRYKELSQSLIVLPAHYSKISE
EECCEEEECCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEHHHHHHHH
MDESGIVSAKLKDLFEHNAGLNIEDEGEFRKVVTENLPPQPNAYQEIRQTNMGQLNPNED
CCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCC
EEREMEIGPNRCAVHN
CHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]