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The map label for this gene is inA [H]

Identifier: 222094425

GI number: 222094425

Start: 738184

End: 740583

Strand: Direct

Name: inA [H]

Synonym: BCQ_0739

Alternate gene names: 222094425

Gene position: 738184-740583 (Clockwise)

Preceding gene: 222094424

Following gene: 222094427

Centisome position: 14.16

GC content: 37.75

Gene sequence:

>2400_bases
ATGAGAAGAAAAGCGCCATTTAAAGTGTTATCGTCATTAGCAATTGCGGCAATTATCGGATGCACATCTGTAATGAGTGC
TCCATTAGCGTACGCAGAAACGCCAGCAAAAGAGAAAGAAAATGTATCTACAACACCAATTGATTACAATTTAATTCAAG
AAGATCGTCTAGCGGAAGCGCTGAAAGAAAGAGGAGAAATTAATCCAGCATCTTCTAAAGAAGAGACGAAAAAGGCTGTC
GAGCAATATATTGAAAAGAAACAAGGAGATCAGGCAAATAAAGAAATTCTTCCAGCTGATACTGCTAAAGAGGCATCTGA
TTTCGTGAAAAAAATAAAAGAGAAAAAAATGGAAGAAAAGGAAAAGGTAAAGAAACCTGAAAAAAACGTTAGCCCTGAGC
AAAAGCCTGAACCAAATAAAAAACAATTGAACGGACAAGTTCCAACATCTAAAGCAAAGCAAGCACCGTATAAGGGATCT
GTTCGAACGGATAAGGTATTAGTGTTACTCGTTGAATTTAGTGATTATAAACATAATAATATTGATCAAACACCAGGGTA
TATGTATTCGAATGACTTTAGTAGAGAGCATTATCAAAAGATGTTATTTGGTAATGAGCCGTACACGTTATTTGATGGTT
CAAAAGTAAAAACGTTTAAACAATATTATGAAGAGCAGTCTGGTGGTAGTTATACGACAGACGGATATGTAACGGAGTGG
CTAACAGTTCCAGGAAAAGCATCTGACTACGGTGCTGATGGTAGCAGTGGTCACGATAATAAAGGTCCGAAAGGTGCACG
TGATTTAGTGAAAGAAGCTTTGCATGCAGCTGCTGAGAAAGGATTAGATTTATCTCAATTTGATCAGTTTGATAGATATG
ATACAAACGGGGATGGGAATCAAAATGAGCCTGACGGTGTAATTGATCATTTAATGGTAATCCATGCTGGTGTTGGTCAA
GAAGCAGGTGGTGGTAAATTAGGCGATGATGCCATTTGGTCACATCGTTCAAAATTAGCAGTAGATCCAGTAGCGATTGA
AGGCACAAAATCAAAAGTAGATTACTTTGGTGGAAAAGTAGCAGCACATGATTACACAATTGAACCAGAAGATGGAGCAG
TAGGTGTGTTTGCGCATGAATTTGGACATGACCTTGGCTTACCAGATGAATATGATACGAAATATACTGGAACCGGTTCA
CCTGTCGAAGCTTGGTCATTAATGAGTGGAGGTAGTTGGACAGGGAAAATTGCAGGAACAGAGCCAACTAGTTTCTCACC
ACAAAATAAAGATTTCTTACAAAAGAATATGGGTGGCAACTGGGCAAAAATTTTAGAAGTAGATTACGATAAAATTAAGC
GTGGTGTAGGAGTTCCTACATATATTGATCAAAGTGTTACGAAATCAAATCGTCCAGGCGTTGTACGTGTTAACTTACCA
GGCAAAAGCGTTGAAACGATTAAACCGGAGTTTGGAAAGCATGCATATTATAGTACAAGAGGCGATGATATGCATACAAC
ATTAGAAACACCGTTCTTTGATTTAACAAAAGGAACAAATGCAAAGTTTGATTATAAAGCAAATTATGAGTTAGAAGCAG
AGTGCGATTTTGTTGAAGTGCATGCAGTAACAGAAGATGGAACGAAAACATTAATTGATAGACTTGGAGAAAAAGTAGTC
CAAGGAGATAAAGATACAACAGATGGGAAATGGATTGATAAGTCATACGATTTAAGTCAATTTAAAGGGAAAAAGGTAAA
ACTGCAATTCGATTATATTACAGATCCAGCAGTAACGTATAAAGGCTTCGCGATGGATAATGTAAATGTAACAGTTGATG
GACAAGTAGTGTTTTCTGATGATGCAGAAGGAACATCAAAAATGCAGTTAAATGGATTCGTTGTTTCTGATGGAACAGAG
AAAAAAGCTCATTATTACTACTTAGAGTGGAGAAACTATGCGGGATCAGATAATGGATTAAAAGCAGGAAAAGGTCCAGT
GTATAATACAGGTCTTGTCGTTTGGTATGCAGATGATAGCTTTAAAGATAACTGGGTTGGGGTGCATCCAGGTGAAGGGT
TCCTTGGTGTTGTAGATTCGCATCCAGAGGCACTTGTTGGCAATTTAAACGGAAAACCAACTTACGGTAATACAGGTATG
CAAATTGCAGACGCAGCATTTTCATTTGATCAAACACCAGCATGGAGTGTAAATTCATTCACACGTGGACAGTTTAACTA
TTCTGGATTACAAGGCGTTACAACTTTTGATGATTCAAAAGTATATAGTAACAACCAAATTGCAGATGCAGGAAGAAAAG
TTCCGAATCTTGGACTTAAATTCCAAGTTGTTGGACAGGCAGATGATAAATCAGCAGGCGCTGTTTGGATTAAACGTTAA

Upstream 100 bases:

>100_bases
TTTTTATATAGGGAGGGCAGAAAGTAGAGCTTTTGATTTAAATGCACTTATTTATCCCACTTTATCTGAATTTTAAGTTT
TATAAAAGGAGAGAAATGAA

Downstream 100 bases:

>100_bases
TAACAGAAAAGCACATTCTTCATATGAAGAATGTGCTTTTGAATTTGTACAGTAAGTTATTATTTTAGCTTATGTAATAC
AAGTGTCTGTTTATATGTAG

Product: immune inhibitor a, metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 799; Mature: 799

Protein sequence:

>799_residues
MRRKAPFKVLSSLAIAAIIGCTSVMSAPLAYAETPAKEKENVSTTPIDYNLIQEDRLAEALKERGEINPASSKEETKKAV
EQYIEKKQGDQANKEILPADTAKEASDFVKKIKEKKMEEKEKVKKPEKNVSPEQKPEPNKKQLNGQVPTSKAKQAPYKGS
VRTDKVLVLLVEFSDYKHNNIDQTPGYMYSNDFSREHYQKMLFGNEPYTLFDGSKVKTFKQYYEEQSGGSYTTDGYVTEW
LTVPGKASDYGADGSSGHDNKGPKGARDLVKEALHAAAEKGLDLSQFDQFDRYDTNGDGNQNEPDGVIDHLMVIHAGVGQ
EAGGGKLGDDAIWSHRSKLAVDPVAIEGTKSKVDYFGGKVAAHDYTIEPEDGAVGVFAHEFGHDLGLPDEYDTKYTGTGS
PVEAWSLMSGGSWTGKIAGTEPTSFSPQNKDFLQKNMGGNWAKILEVDYDKIKRGVGVPTYIDQSVTKSNRPGVVRVNLP
GKSVETIKPEFGKHAYYSTRGDDMHTTLETPFFDLTKGTNAKFDYKANYELEAECDFVEVHAVTEDGTKTLIDRLGEKVV
QGDKDTTDGKWIDKSYDLSQFKGKKVKLQFDYITDPAVTYKGFAMDNVNVTVDGQVVFSDDAEGTSKMQLNGFVVSDGTE
KKAHYYYLEWRNYAGSDNGLKAGKGPVYNTGLVVWYADDSFKDNWVGVHPGEGFLGVVDSHPEALVGNLNGKPTYGNTGM
QIADAAFSFDQTPAWSVNSFTRGQFNYSGLQGVTTFDDSKVYSNNQIADAGRKVPNLGLKFQVVGQADDKSAGAVWIKR

Sequences:

>Translated_799_residues
MRRKAPFKVLSSLAIAAIIGCTSVMSAPLAYAETPAKEKENVSTTPIDYNLIQEDRLAEALKERGEINPASSKEETKKAV
EQYIEKKQGDQANKEILPADTAKEASDFVKKIKEKKMEEKEKVKKPEKNVSPEQKPEPNKKQLNGQVPTSKAKQAPYKGS
VRTDKVLVLLVEFSDYKHNNIDQTPGYMYSNDFSREHYQKMLFGNEPYTLFDGSKVKTFKQYYEEQSGGSYTTDGYVTEW
LTVPGKASDYGADGSSGHDNKGPKGARDLVKEALHAAAEKGLDLSQFDQFDRYDTNGDGNQNEPDGVIDHLMVIHAGVGQ
EAGGGKLGDDAIWSHRSKLAVDPVAIEGTKSKVDYFGGKVAAHDYTIEPEDGAVGVFAHEFGHDLGLPDEYDTKYTGTGS
PVEAWSLMSGGSWTGKIAGTEPTSFSPQNKDFLQKNMGGNWAKILEVDYDKIKRGVGVPTYIDQSVTKSNRPGVVRVNLP
GKSVETIKPEFGKHAYYSTRGDDMHTTLETPFFDLTKGTNAKFDYKANYELEAECDFVEVHAVTEDGTKTLIDRLGEKVV
QGDKDTTDGKWIDKSYDLSQFKGKKVKLQFDYITDPAVTYKGFAMDNVNVTVDGQVVFSDDAEGTSKMQLNGFVVSDGTE
KKAHYYYLEWRNYAGSDNGLKAGKGPVYNTGLVVWYADDSFKDNWVGVHPGEGFLGVVDSHPEALVGNLNGKPTYGNTGM
QIADAAFSFDQTPAWSVNSFTRGQFNYSGLQGVTTFDDSKVYSNNQIADAGRKVPNLGLKFQVVGQADDKSAGAVWIKR
>Mature_799_residues
MRRKAPFKVLSSLAIAAIIGCTSVMSAPLAYAETPAKEKENVSTTPIDYNLIQEDRLAEALKERGEINPASSKEETKKAV
EQYIEKKQGDQANKEILPADTAKEASDFVKKIKEKKMEEKEKVKKPEKNVSPEQKPEPNKKQLNGQVPTSKAKQAPYKGS
VRTDKVLVLLVEFSDYKHNNIDQTPGYMYSNDFSREHYQKMLFGNEPYTLFDGSKVKTFKQYYEEQSGGSYTTDGYVTEW
LTVPGKASDYGADGSSGHDNKGPKGARDLVKEALHAAAEKGLDLSQFDQFDRYDTNGDGNQNEPDGVIDHLMVIHAGVGQ
EAGGGKLGDDAIWSHRSKLAVDPVAIEGTKSKVDYFGGKVAAHDYTIEPEDGAVGVFAHEFGHDLGLPDEYDTKYTGTGS
PVEAWSLMSGGSWTGKIAGTEPTSFSPQNKDFLQKNMGGNWAKILEVDYDKIKRGVGVPTYIDQSVTKSNRPGVVRVNLP
GKSVETIKPEFGKHAYYSTRGDDMHTTLETPFFDLTKGTNAKFDYKANYELEAECDFVEVHAVTEDGTKTLIDRLGEKVV
QGDKDTTDGKWIDKSYDLSQFKGKKVKLQFDYITDPAVTYKGFAMDNVNVTVDGQVVFSDDAEGTSKMQLNGFVVSDGTE
KKAHYYYLEWRNYAGSDNGLKAGKGPVYNTGLVVWYADDSFKDNWVGVHPGEGFLGVVDSHPEALVGNLNGKPTYGNTGM
QIADAAFSFDQTPAWSVNSFTRGQFNYSGLQGVTTFDDSKVYSNNQIADAGRKVPNLGLKFQVVGQADDKSAGAVWIKR

Specific function: Neutral metalloprotease that is secreted to degrade antibacterial proteins produced by the insect host for its defense (attacins and cecropins). Probably degrades some unknown crucial protein(s) too, since it is toxic when injected to insect larvae [H]

COG id: COG4412

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M6 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012300
- InterPro:   IPR008757 [H]

Pfam domain/function: PF05547 Peptidase_M6 [H]

EC number: NA

Molecular weight: Translated: 87946; Mature: 87946

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRKAPFKVLSSLAIAAIIGCTSVMSAPLAYAETPAKEKENVSTTPIDYNLIQEDRLAEA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LKERGEINPASSKEETKKAVEQYIEKKQGDQANKEILPADTAKEASDFVKKIKEKKMEEK
HHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EKVKKPEKNVSPEQKPEPNKKQLNGQVPTSKAKQAPYKGSVRTDKVLVLLVEFSDYKHNN
HHHCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHCCCCCCCCCCCEEEEEEEEECCCCCCC
IDQTPGYMYSNDFSREHYQKMLFGNEPYTLFDGSKVKTFKQYYEEQSGGSYTTDGYVTEW
CCCCCCEEECCCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCEEEEE
LTVPGKASDYGADGSSGHDNKGPKGARDLVKEALHAAAEKGLDLSQFDQFDRYDTNGDGN
EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCC
QNEPDGVIDHLMVIHAGVGQEAGGGKLGDDAIWSHRSKLAVDPVAIEGTKSKVDYFGGKV
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCEEECCEEECCCCHHHHHCCCEE
AAHDYTIEPEDGAVGVFAHEFGHDLGLPDEYDTKYTGTGSPVEAWSLMSGGSWTGKIAGT
EECCEEECCCCCEEEEEEHHHCCCCCCCCCCCCCCCCCCCCHHHHEECCCCCEEEEECCC
EPTSFSPQNKDFLQKNMGGNWAKILEVDYDKIKRGVGVPTYIDQSVTKSNRPGVVRVNLP
CCCCCCCCCHHHHHHCCCCCEEEEEECCHHHHHHCCCCCHHHHHHHHCCCCCCEEEEECC
GKSVETIKPEFGKHAYYSTRGDDMHTTLETPFFDLTKGTNAKFDYKANYELEAECDFVEV
CCCCHHCCCCCCCCCEEECCCCCCEEECCCCCEEECCCCCCEEEEECCCEEECCCCEEEE
HAVTEDGTKTLIDRLGEKVVQGDKDTTDGKWIDKSYDLSQFKGKKVKLQFDYITDPAVTY
EEECCCCHHHHHHHHHHHHHCCCCCCCCCCEECCCCCHHHCCCCEEEEEEEEECCCCEEE
KGFAMDNVNVTVDGQVVFSDDAEGTSKMQLNGFVVSDGTEKKAHYYYLEWRNYAGSDNGL
ECEEECCEEEEECCEEEECCCCCCCCEEEEEEEEEECCCCCCEEEEEEEEECCCCCCCCC
KAGKGPVYNTGLVVWYADDSFKDNWVGVHPGEGFLGVVDSHPEALVGNLNGKPTYGNTGM
CCCCCCCEECCEEEEEECCCCCCCEEEECCCCCCEEEECCCCCCEEECCCCCCCCCCCCC
QIADAAFSFDQTPAWSVNSFTRGQFNYSGLQGVTTFDDSKVYSNNQIADAGRKVPNLGLK
EEHHHHHCCCCCCCCCCCCEECCCCCCCCCCCEEECCCCCCCCCCCHHHHCCCCCCCCEE
FQVVGQADDKSAGAVWIKR
EEEEECCCCCCCCEEEEEC
>Mature Secondary Structure
MRRKAPFKVLSSLAIAAIIGCTSVMSAPLAYAETPAKEKENVSTTPIDYNLIQEDRLAEA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LKERGEINPASSKEETKKAVEQYIEKKQGDQANKEILPADTAKEASDFVKKIKEKKMEEK
HHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EKVKKPEKNVSPEQKPEPNKKQLNGQVPTSKAKQAPYKGSVRTDKVLVLLVEFSDYKHNN
HHHCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHCCCCCCCCCCCEEEEEEEEECCCCCCC
IDQTPGYMYSNDFSREHYQKMLFGNEPYTLFDGSKVKTFKQYYEEQSGGSYTTDGYVTEW
CCCCCCEEECCCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCEEEEE
LTVPGKASDYGADGSSGHDNKGPKGARDLVKEALHAAAEKGLDLSQFDQFDRYDTNGDGN
EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCC
QNEPDGVIDHLMVIHAGVGQEAGGGKLGDDAIWSHRSKLAVDPVAIEGTKSKVDYFGGKV
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCEEECCEEECCCCHHHHHCCCEE
AAHDYTIEPEDGAVGVFAHEFGHDLGLPDEYDTKYTGTGSPVEAWSLMSGGSWTGKIAGT
EECCEEECCCCCEEEEEEHHHCCCCCCCCCCCCCCCCCCCCHHHHEECCCCCEEEEECCC
EPTSFSPQNKDFLQKNMGGNWAKILEVDYDKIKRGVGVPTYIDQSVTKSNRPGVVRVNLP
CCCCCCCCCHHHHHHCCCCCEEEEEECCHHHHHHCCCCCHHHHHHHHCCCCCCEEEEECC
GKSVETIKPEFGKHAYYSTRGDDMHTTLETPFFDLTKGTNAKFDYKANYELEAECDFVEV
CCCCHHCCCCCCCCCEEECCCCCCEEECCCCCEEECCCCCCEEEEECCCEEECCCCEEEE
HAVTEDGTKTLIDRLGEKVVQGDKDTTDGKWIDKSYDLSQFKGKKVKLQFDYITDPAVTY
EEECCCCHHHHHHHHHHHHHCCCCCCCCCCEECCCCCHHHCCCCEEEEEEEEECCCCEEE
KGFAMDNVNVTVDGQVVFSDDAEGTSKMQLNGFVVSDGTEKKAHYYYLEWRNYAGSDNGL
ECEEECCEEEEECCEEEECCCCCCCCEEEEEEEEEECCCCCCEEEEEEEEECCCCCCCCC
KAGKGPVYNTGLVVWYADDSFKDNWVGVHPGEGFLGVVDSHPEALVGNLNGKPTYGNTGM
CCCCCCCEECCEEEEEECCCCCCCEEEECCCCCCEEEECCCCCCEEECCCCCCCCCCCCC
QIADAAFSFDQTPAWSVNSFTRGQFNYSGLQGVTTFDDSKVYSNNQIADAGRKVPNLGLK
EEHHHHHCCCCCCCCCCCCEECCCCCCCCCCCEEECCCCCCCCCCCHHHHCCCCCCCCEE
FQVVGQADDKSAGAVWIKR
EEEEECCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2089225; 6421577 [H]