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The map label for this gene is yrfF [C]

Identifier: 22127792

GI number: 22127792

Start: 4378099

End: 4380246

Strand: Reverse

Name: yrfF [C]

Synonym: y3922

Alternate gene names: 22127792

Gene position: 4380246-4378099 (Counterclockwise)

Preceding gene: 229013118

Following gene: 22127791

Centisome position: 95.21

GC content: 48.37

Gene sequence:

>2148_bases
ATGAGCACAATAGTTTTAATATTGGCCTTACTGTTGACCAGTCTGATCGCCGTAGGTCTGCTGTGGTGGCTCCGATTCCG
CCGCCCTCACCCCATAACAGCAGCGTTGCCGTTTGTTAAACTGACACACCGAAAACTCACGCCAGAAGAGCGAGTGAGTA
TCGAAAATTATCTGCGTAATCAGCAAAATAAGCATGGTTTTAACACGCAACCGGCTTTTGATTCCCACGCACTGGCAGCC
AGTACCTCATCCACCCCAATGTTGGTGCTCACACCGCAAAGTGATAACGTCTATTCCGTTACCCGCGCCATTACCCGCTA
TGGTGTCGCCAGCGATGAGCCAAATAAATGGCGCTATTATCTCGATTCAATAGAAGTTCATCTGCCCTCGGCCTGGGAAC
AATATATTACTCAGGATAATGATGTTGAGCTTATCCAAACCCAGACAATCCCGCTGGTGATCTCCCTTAATGGGCATACG
CTTAACAATCATCAGTCTGAGAATACCTATCAGCCCATTTTACCTTCAGTATCGAAAAATGCGTCTATTCGCAAAGAAGA
TAGCGAACATATTGAGCTGCTTAATATCCGTAAGGAAACCCCGGAAGAATATGCTCTGCATGGCCCCAATGGTTTAAAAG
AAGCCTGCGCCATTTGCATAGCTTTATTGTTGCTGTTTTTCGCATTATCTGGGCCGACGGTGACACTACCCTGGCTGGTT
ATCGTGGCAGTGTCATTAACCTGTTGGGCGTGTTGGTACCTCTTCCGCCCCTTGTCAGAAAAAGATTTGCGGGAAGTGCA
CTGCTTAAATGGTACCCCCAAACGCTGGGGCCTGTTTGGCGAGTCAAATCAGGGGCAGATAAACAATATCTCACTCGGGA
TCGTTGATCTCATTTATCCGGCGCATTGGGGACCTTATTTTGTACATGATTTAGGCAAAAAAACCCATATTGATATCTAC
CTTAATCGCCAGGTTGTACGTCAGGGGGCTTTTTTATCCCTCCATGATGAAATGAAAATGTTCCCGTTACAGCGCTGGGG
GAAAAACCTAACCTTGATCGTCGGCTCACTGTTGGTTCTGGTGTTATTACTGATTTACGTACCGCTCGGTCTCCCCCTAA
AGTTGAGCGTTGCCTGGTTGCAAGGGGCTCAAAGCCAACAGGTGACCAGCGTCGCAGCACTGGACAAAATGCCACTACGC
ATCGGCGATATGCTGAAGGCTCAGGGTAATGGCATGTGCTATGTCCCCCCCAACATTCAAAACACACGCGGTTTCGTTTT
CACCCCCTTTGATTGCTCCGGTATTTATTGGAATACCGCCTCCCCCTTGCCACAACCTGAATCTGAAACCATAGAAAAAG
CTGCGGCACTGGTAGAAACAATCAATAAACAACTGCACCCGCAGGGCTCTGATGCCAGCGTCAACCCGAAACTGGCTACC
GCCATTGAGAAATCGGGCATGATTTTATTGGACGATTTTTCTGACATTGTGCTGAAAACACAGGCGTTATGTAGCGAAAA
TACCGATTGTATTCGCCTGAAGAATGCACTGGTTAATCTGGGAAATGCCAAAAACTGGTCAGCCTTGGTCAAACGGGCGC
AATCCGGGAATTTGGAAGGGATGAATGTTCTGTTACGCCCGATCAGTGCCGATGTACTGGAAAATTTGATTAATACCGCT
GCGTCATCATTCGTTTATCGTGAAACGCATTTAGCAACAGAAGCGTTGAATAGCCCACCTCCGGGCGGTTTTTTGATCAC
CAGCGATGAGGGCAAGCAGTTAGTGAACCACCCTGCGCCAACGCTGCCCCTGTTTGACTACAGCGCACTGGAACAGTGGC
GGGAATTGCAACGGCTCTCGGCGTTGCTACTTGATACCCCATTTAAAGCGGAAGGGATTATTACCAATATCACGACTGAT
GCGAATGGCACACGGCATATTGCGCTGCATAGTGAGCCGGACATTGTCACTCTGGGTCGCTATCTGGCGACCAGCCTGCT
ATTGCTGGTGCTGATTTTTTGCCTGGTCGTCAATATGGTCTTGTTGATTCAACGTGCCATGAAAAATCGTCGCCGGATGG
ATAACATTCAACGTTATTATGACGATTGCTTTAATCAAACGCTCACACCGCCCCCCTTCTTGCGCTAG

Upstream 100 bases:

>100_bases
AGGCACTAAATCGTTGAGTTATTAGGCCATATGCCTCCGCACTTTTTTATGTATTTTTCATAGCGTTGACGTAAATTTAA
AGCGCTCTGATGGGGATGGG

Downstream 100 bases:

>100_bases
CTCACCCATCTCCGGTTGATCATCGCTCATGCCAGCAGATGCACGGTGTAACATGGATATGCTAGGCTAGCTTTATCTAC
TCGCTTATAGCAGAAAATAT

Product: dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 715; Mature: 714

Protein sequence:

>715_residues
MSTIVLILALLLTSLIAVGLLWWLRFRRPHPITAALPFVKLTHRKLTPEERVSIENYLRNQQNKHGFNTQPAFDSHALAA
STSSTPMLVLTPQSDNVYSVTRAITRYGVASDEPNKWRYYLDSIEVHLPSAWEQYITQDNDVELIQTQTIPLVISLNGHT
LNNHQSENTYQPILPSVSKNASIRKEDSEHIELLNIRKETPEEYALHGPNGLKEACAICIALLLLFFALSGPTVTLPWLV
IVAVSLTCWACWYLFRPLSEKDLREVHCLNGTPKRWGLFGESNQGQINNISLGIVDLIYPAHWGPYFVHDLGKKTHIDIY
LNRQVVRQGAFLSLHDEMKMFPLQRWGKNLTLIVGSLLVLVLLLIYVPLGLPLKLSVAWLQGAQSQQVTSVAALDKMPLR
IGDMLKAQGNGMCYVPPNIQNTRGFVFTPFDCSGIYWNTASPLPQPESETIEKAAALVETINKQLHPQGSDASVNPKLAT
AIEKSGMILLDDFSDIVLKTQALCSENTDCIRLKNALVNLGNAKNWSALVKRAQSGNLEGMNVLLRPISADVLENLINTA
ASSFVYRETHLATEALNSPPPGGFLITSDEGKQLVNHPAPTLPLFDYSALEQWRELQRLSALLLDTPFKAEGIITNITTD
ANGTRHIALHSEPDIVTLGRYLATSLLLLVLIFCLVVNMVLLIQRAMKNRRRMDNIQRYYDDCFNQTLTPPPFLR

Sequences:

>Translated_715_residues
MSTIVLILALLLTSLIAVGLLWWLRFRRPHPITAALPFVKLTHRKLTPEERVSIENYLRNQQNKHGFNTQPAFDSHALAA
STSSTPMLVLTPQSDNVYSVTRAITRYGVASDEPNKWRYYLDSIEVHLPSAWEQYITQDNDVELIQTQTIPLVISLNGHT
LNNHQSENTYQPILPSVSKNASIRKEDSEHIELLNIRKETPEEYALHGPNGLKEACAICIALLLLFFALSGPTVTLPWLV
IVAVSLTCWACWYLFRPLSEKDLREVHCLNGTPKRWGLFGESNQGQINNISLGIVDLIYPAHWGPYFVHDLGKKTHIDIY
LNRQVVRQGAFLSLHDEMKMFPLQRWGKNLTLIVGSLLVLVLLLIYVPLGLPLKLSVAWLQGAQSQQVTSVAALDKMPLR
IGDMLKAQGNGMCYVPPNIQNTRGFVFTPFDCSGIYWNTASPLPQPESETIEKAAALVETINKQLHPQGSDASVNPKLAT
AIEKSGMILLDDFSDIVLKTQALCSENTDCIRLKNALVNLGNAKNWSALVKRAQSGNLEGMNVLLRPISADVLENLINTA
ASSFVYRETHLATEALNSPPPGGFLITSDEGKQLVNHPAPTLPLFDYSALEQWRELQRLSALLLDTPFKAEGIITNITTD
ANGTRHIALHSEPDIVTLGRYLATSLLLLVLIFCLVVNMVLLIQRAMKNRRRMDNIQRYYDDCFNQTLTPPPFLR
>Mature_714_residues
STIVLILALLLTSLIAVGLLWWLRFRRPHPITAALPFVKLTHRKLTPEERVSIENYLRNQQNKHGFNTQPAFDSHALAAS
TSSTPMLVLTPQSDNVYSVTRAITRYGVASDEPNKWRYYLDSIEVHLPSAWEQYITQDNDVELIQTQTIPLVISLNGHTL
NNHQSENTYQPILPSVSKNASIRKEDSEHIELLNIRKETPEEYALHGPNGLKEACAICIALLLLFFALSGPTVTLPWLVI
VAVSLTCWACWYLFRPLSEKDLREVHCLNGTPKRWGLFGESNQGQINNISLGIVDLIYPAHWGPYFVHDLGKKTHIDIYL
NRQVVRQGAFLSLHDEMKMFPLQRWGKNLTLIVGSLLVLVLLLIYVPLGLPLKLSVAWLQGAQSQQVTSVAALDKMPLRI
GDMLKAQGNGMCYVPPNIQNTRGFVFTPFDCSGIYWNTASPLPQPESETIEKAAALVETINKQLHPQGSDASVNPKLATA
IEKSGMILLDDFSDIVLKTQALCSENTDCIRLKNALVNLGNAKNWSALVKRAQSGNLEGMNVLLRPISADVLENLINTAA
SSFVYRETHLATEALNSPPPGGFLITSDEGKQLVNHPAPTLPLFDYSALEQWRELQRLSALLLDTPFKAEGIITNITTDA
NGTRHIALHSEPDIVTLGRYLATSLLLLVLIFCLVVNMVLLIQRAMKNRRRMDNIQRYYDDCFNQTLTPPPFLR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the igaA family

Homologues:

Organism=Escherichia coli, GI1789801, Length=719, Percent_Identity=53.4075104311544, Blast_Score=706, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IGAA_YERPE (P58722)

Other databases:

- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AC0018
- RefSeq:   NP_671215.1
- RefSeq:   NP_991544.1
- RefSeq:   YP_002345228.1
- ProteinModelPortal:   P58722
- IntAct:   P58722
- GeneID:   1148869
- GeneID:   1172988
- GeneID:   2764292
- GenomeReviews:   AE009952_GR
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO0142
- KEGG:   ypk:y3922
- KEGG:   ypm:YP_0143
- HOGENOM:   HBG417125
- OMA:   ISLNGHS
- ProtClustDB:   CLSK880647
- BioCyc:   YPES187410:Y3922-MONOMER
- BioCyc:   YPES214092:YPO0142-MONOMER
- InterPro:   IPR010771
- ProDom:   PD147088

Pfam domain/function: PF07095 IgaA

EC number: NA

Molecular weight: Translated: 80006; Mature: 79875

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12b9f694)-; HASH(0x12789bfc)-; HASH(0x126fcaa8)-; HASH(0x130c8efc)-; HASH(0x13033894)-;

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIVLILALLLTSLIAVGLLWWLRFRRPHPITAALPFVKLTHRKLTPEERVSIENYLRN
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHC
QQNKHGFNTQPAFDSHALAASTSSTPMLVLTPQSDNVYSVTRAITRYGVASDEPNKWRYY
CCCCCCCCCCCCCCCCCEEECCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEE
LDSIEVHLPSAWEQYITQDNDVELIQTQTIPLVISLNGHTLNNHQSENTYQPILPSVSKN
EEEEEEECCHHHHHHCCCCCCEEEEEECCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
ASIRKEDSEHIELLNIRKETPEEYALHGPNGLKEACAICIALLLLFFALSGPTVTLPWLV
CCCCCCCCCCEEEEECCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
IVAVSLTCWACWYLFRPLSEKDLREVHCLNGTPKRWGLFGESNQGQINNISLGIVDLIYP
HHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHCCCCCCCCCCCEEEEEEEHHHHHHC
AHWGPYFVHDLGKKTHIDIYLNRQVVRQGAFLSLHDEMKMFPLQRWGKNLTLIVGSLLVL
CCCCCHHHHHCCCCEEEEEEECHHHHHCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHHH
VLLLIYVPLGLPLKLSVAWLQGAQSQQVTSVAALDKMPLRIGDMLKAQGNGMCYVPPNIQ
HHHHHHHCCCCCCEEEEHHHCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCCCC
NTRGFVFTPFDCSGIYWNTASPLPQPESETIEKAAALVETINKQLHPQGSDASVNPKLAT
CCCCCEEECCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
AIEKSGMILLDDFSDIVLKTQALCSENTDCIRLKNALVNLGNAKNWSALVKRAQSGNLEG
HHHHCCEEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCC
MNVLLRPISADVLENLINTAASSFVYRETHLATEALNSPPPGGFLITSDEGKQLVNHPAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHCCCCC
TLPLFDYSALEQWRELQRLSALLLDTPFKAEGIITNITTDANGTRHIALHSEPDIVTLGR
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEECCCCCEEHHHH
YLATSLLLLVLIFCLVVNMVLLIQRAMKNRRRMDNIQRYYDDCFNQTLTPPPFLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
>Mature Secondary Structure 
STIVLILALLLTSLIAVGLLWWLRFRRPHPITAALPFVKLTHRKLTPEERVSIENYLRN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHC
QQNKHGFNTQPAFDSHALAASTSSTPMLVLTPQSDNVYSVTRAITRYGVASDEPNKWRYY
CCCCCCCCCCCCCCCCCEEECCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEE
LDSIEVHLPSAWEQYITQDNDVELIQTQTIPLVISLNGHTLNNHQSENTYQPILPSVSKN
EEEEEEECCHHHHHHCCCCCCEEEEEECCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
ASIRKEDSEHIELLNIRKETPEEYALHGPNGLKEACAICIALLLLFFALSGPTVTLPWLV
CCCCCCCCCCEEEEECCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
IVAVSLTCWACWYLFRPLSEKDLREVHCLNGTPKRWGLFGESNQGQINNISLGIVDLIYP
HHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHCCCCCCCCCCCEEEEEEEHHHHHHC
AHWGPYFVHDLGKKTHIDIYLNRQVVRQGAFLSLHDEMKMFPLQRWGKNLTLIVGSLLVL
CCCCCHHHHHCCCCEEEEEEECHHHHHCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHHH
VLLLIYVPLGLPLKLSVAWLQGAQSQQVTSVAALDKMPLRIGDMLKAQGNGMCYVPPNIQ
HHHHHHHCCCCCCEEEEHHHCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCCCC
NTRGFVFTPFDCSGIYWNTASPLPQPESETIEKAAALVETINKQLHPQGSDASVNPKLAT
CCCCCEEECCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
AIEKSGMILLDDFSDIVLKTQALCSENTDCIRLKNALVNLGNAKNWSALVKRAQSGNLEG
HHHHCCEEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCC
MNVLLRPISADVLENLINTAASSFVYRETHLATEALNSPPPGGFLITSDEGKQLVNHPAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHCCCCC
TLPLFDYSALEQWRELQRLSALLLDTPFKAEGIITNITTDANGTRHIALHSEPDIVTLGR
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEECCCCCEEHHHH
YLATSLLLLVLIFCLVVNMVLLIQRAMKNRRRMDNIQRYYDDCFNQTLTPPPFLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430