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The map label for this gene is nfuA [H]

Identifier: 22127773

GI number: 22127773

Start: 4361988

End: 4362563

Strand: Reverse

Name: nfuA [H]

Synonym: y3903

Alternate gene names: 22127773

Gene position: 4362563-4361988 (Counterclockwise)

Preceding gene: 22127774

Following gene: 22127771

Centisome position: 94.82

GC content: 46.88

Gene sequence:

>576_bases
ATGATCACAATAACAGACGCAGCACAATCTCATTTTGCCAAACTGTTGGCAAATCAAGAAGAAGGCACCCAAATTCGTGT
ATTTGTTATCAATCCAGGGACACCAACTGCTGAATGCGGTGTTTCCTATTGCCCACCGGATGCGGTTGAAGCAACAGATA
CCGAACTGAAATTCGAGCAATTATCAGCCTATGTTGATGAACTGAGCGTACCTTATCTACAAGACGCTGAAATAGATTTC
GTCACTGACCAGCTCGGCTCTCAGTTAACCTTGAAAGCACCGAACGCTAAAATGCGTAAAGTAGACGATAGCGCGCCACT
GATGGAACGGGTTGAGTATGTTCTGCAATCGCAGATTAACCCACAATTGGCTGGCCACGGTGGCCGAGTGACACTGATGG
AAATCACACCAGAGGGGTTGGCTATCCTGCAATTCGGCGGCGGTTGTAACGGTTGCTCTATGGTCGATGTCACTTTGAAA
GAAGGCATCGAGAAGGAGTTGTTGCAGAAATTCCCAGAATTGAAAGGGGTAAGAGATTTAACCGAGCATCAGCGTGGCGA
GCACTCTTATTACTAA

Upstream 100 bases:

>100_bases
TTGCCTCATTACAAATCTGGAGTGTCTGCCGAACCTTGTAGTCACCCTAGCAATGGGCGTATTATAACCGACAAGAGTAG
TCAACTATTGAGCAGATGCC

Downstream 100 bases:

>100_bases
TTAATTACCCTTTGTCATTGGCGCTACAGCGGCGTTACCTGCGCTCACTCACCCGAATCACTTACTTATGTAAGCTCATC
GGGCTTTGCTTGCTTGCCGC

Product: putative DNA uptake protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MITITDAAQSHFAKLLANQEEGTQIRVFVINPGTPTAECGVSYCPPDAVEATDTELKFEQLSAYVDELSVPYLQDAEIDF
VTDQLGSQLTLKAPNAKMRKVDDSAPLMERVEYVLQSQINPQLAGHGGRVTLMEITPEGLAILQFGGGCNGCSMVDVTLK
EGIEKELLQKFPELKGVRDLTEHQRGEHSYY

Sequences:

>Translated_191_residues
MITITDAAQSHFAKLLANQEEGTQIRVFVINPGTPTAECGVSYCPPDAVEATDTELKFEQLSAYVDELSVPYLQDAEIDF
VTDQLGSQLTLKAPNAKMRKVDDSAPLMERVEYVLQSQINPQLAGHGGRVTLMEITPEGLAILQFGGGCNGCSMVDVTLK
EGIEKELLQKFPELKGVRDLTEHQRGEHSYY
>Mature_191_residues
MITITDAAQSHFAKLLANQEEGTQIRVFVINPGTPTAECGVSYCPPDAVEATDTELKFEQLSAYVDELSVPYLQDAEIDF
VTDQLGSQLTLKAPNAKMRKVDDSAPLMERVEYVLQSQINPQLAGHGGRVTLMEITPEGLAILQFGGGCNGCSMVDVTLK
EGIEKELLQKFPELKGVRDLTEHQRGEHSYY

Specific function: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins [H]

COG id: COG0694

COG function: function code O; Thioredoxin-like proteins and domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nfuA family [H]

Homologues:

Organism=Escherichia coli, GI1789819, Length=191, Percent_Identity=89.5287958115183, Blast_Score=360, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017726
- InterPro:   IPR000361
- InterPro:   IPR001075
- ProDom:   PD002830 [H]

Pfam domain/function: PF01521 Fe-S_biosyn; PF01106 NifU [H]

EC number: NA

Molecular weight: Translated: 21004; Mature: 21004

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITITDAAQSHFAKLLANQEEGTQIRVFVINPGTPTAECGVSYCPPDAVEATDTELKFEQ
CEEECHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHCCCCCCCCCCCCCCCCHHHHHH
LSAYVDELSVPYLQDAEIDFVTDQLGSQLTLKAPNAKMRKVDDSAPLMERVEYVLQSQIN
HHHHHHHCCCCCCCCCCCEEEHHHCCCEEEEECCCCHHHCCCCCCHHHHHHHHHHHHCCC
PQLAGHGGRVTLMEITPEGLAILQFGGGCNGCSMVDVTLKEGIEKELLQKFPELKGVRDL
CCCCCCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEHHHCCHHHHHHHHHHHHCCHHHH
TEHQRGEHSYY
HHHHCCCCCCC
>Mature Secondary Structure
MITITDAAQSHFAKLLANQEEGTQIRVFVINPGTPTAECGVSYCPPDAVEATDTELKFEQ
CEEECHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHCCCCCCCCCCCCCCCCHHHHHH
LSAYVDELSVPYLQDAEIDFVTDQLGSQLTLKAPNAKMRKVDDSAPLMERVEYVLQSQIN
HHHHHHHCCCCCCCCCCCEEEHHHCCCEEEEECCCCHHHCCCCCCHHHHHHHHHHHHCCC
PQLAGHGGRVTLMEITPEGLAILQFGGGCNGCSMVDVTLKEGIEKELLQKFPELKGVRDL
CCCCCCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEHHHCCHHHHHHHHHHHHCCHHHH
TEHQRGEHSYY
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA