Click here to switch to the map view.

The map label for this gene is ribF [H]

Identifier: 22127575

GI number: 22127575

Start: 4113900

End: 4114838

Strand: Reverse

Name: ribF [H]

Synonym: y3701

Alternate gene names: 22127575

Gene position: 4114838-4113900 (Counterclockwise)

Preceding gene: 22127577

Following gene: 22127574

Centisome position: 89.44

GC content: 50.05

Gene sequence:

>939_bases
ATGGAGCTAATTCGCGGTATACATAATATCCGGGCACGCCACCATGGTTGCGTGCTGACTATCGGTAACTTTGATGGTGT
CCACCGTGGACATCAGGCTTTATTAGAGCAACTAAAGCGCGAGGGGCAGCGTTTAGGCCTACCCGTTATGGTGATGATAT
TTGAACCGCAACCACTGGAATTGTTTGCAGCAGATAAAGCACCCGCCCGATTGACACGCTTGCGTGATAAAGCCAAATAT
CTGGCTCAGGCTGGGGTTGATTATTTATTGTGCGTTAAGTTTGACCCACGTTTTGCCGCCAATACAGCGCAAGCTTTTGT
TGCTCAGTTGCTGGTAGAGAAATTGGGTGTTAAATTTTTAACGGTAGGTGATGACTTCCGCTTTGGCGCAGGGCGCCAGG
GGGATTTTCAACTACTGCAGCAAGCTGGTGCTGAGTTTGGTTTTGATGTTATCAGCACCGACAGTTTTTGTGATGGCGGC
TTGCGAATCAGCAGCACCGCGATTCGTCAGGCACTGCATGATGATGATTTGGTGTTGGCCGAAACGTTATTGGGTCACCC
GTACAGTATTTCGGGCCGAGTGGTTCACGGTGATGAACTGGGGCGGACGATAGGTTTCCCTACGGCGAATTTGCCGTTAA
AACGTTTAGTTGCTCCGGTGAAAGGGGTGTATGCAGTAGATGTGTATGGTTTGGGTTCAACGCCATTGTATGGTGTCGCG
AATATCGGCACCCGGCCTACCGTTGCTGGCGTCCGTCAGCAGCTTGAGGTTCATCTGCTTGATGTAACTATGGATCTTTA
TGGGTGCCATATTGATGTGGTGCTACGCGCAAAACTGCGCAACGAACAGCGTTTTGCTTCGCTTGAGGCCTTAAAGCAGC
AAATCGCCAACGATGTGGTGACGGCCCGAACATTTTTCGGGCTAAAGACACCGGTTTAA

Upstream 100 bases:

>100_bases
GGCAAAATGGTATGACTTTCGGTTAAAGGTGCCAATCGCGGGTTAACCTTAACCGCTGTACAAGGTATAATCCGGCGATT
CCCACTGTTTTGAGCCAGCT

Downstream 100 bases:

>100_bases
TATTTCTAGCCGAAACGGAACCGAGAATCTAATGAGTGACTACAAGAATACCCTGAACTTGCCTGAAACAGGGTTCCCGA
TGCGCGGCGATCTGGCTAAG

Product: bifunctional riboflavin kinase/FMN adenylyltransferase

Products: NA

Alternate protein names: Riboflavin kinase; Flavokinase; FMN adenylyltransferase; FAD pyrophosphorylase; FAD synthase [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MELIRGIHNIRARHHGCVLTIGNFDGVHRGHQALLEQLKREGQRLGLPVMVMIFEPQPLELFAADKAPARLTRLRDKAKY
LAQAGVDYLLCVKFDPRFAANTAQAFVAQLLVEKLGVKFLTVGDDFRFGAGRQGDFQLLQQAGAEFGFDVISTDSFCDGG
LRISSTAIRQALHDDDLVLAETLLGHPYSISGRVVHGDELGRTIGFPTANLPLKRLVAPVKGVYAVDVYGLGSTPLYGVA
NIGTRPTVAGVRQQLEVHLLDVTMDLYGCHIDVVLRAKLRNEQRFASLEALKQQIANDVVTARTFFGLKTPV

Sequences:

>Translated_312_residues
MELIRGIHNIRARHHGCVLTIGNFDGVHRGHQALLEQLKREGQRLGLPVMVMIFEPQPLELFAADKAPARLTRLRDKAKY
LAQAGVDYLLCVKFDPRFAANTAQAFVAQLLVEKLGVKFLTVGDDFRFGAGRQGDFQLLQQAGAEFGFDVISTDSFCDGG
LRISSTAIRQALHDDDLVLAETLLGHPYSISGRVVHGDELGRTIGFPTANLPLKRLVAPVKGVYAVDVYGLGSTPLYGVA
NIGTRPTVAGVRQQLEVHLLDVTMDLYGCHIDVVLRAKLRNEQRFASLEALKQQIANDVVTARTFFGLKTPV
>Mature_312_residues
MELIRGIHNIRARHHGCVLTIGNFDGVHRGHQALLEQLKREGQRLGLPVMVMIFEPQPLELFAADKAPARLTRLRDKAKY
LAQAGVDYLLCVKFDPRFAANTAQAFVAQLLVEKLGVKFLTVGDDFRFGAGRQGDFQLLQQAGAEFGFDVISTDSFCDGG
LRISSTAIRQALHDDDLVLAETLLGHPYSISGRVVHGDELGRTIGFPTANLPLKRLVAPVKGVYAVDVYGLGSTPLYGVA
NIGTRPTVAGVRQQLEVHLLDVTMDLYGCHIDVVLRAKLRNEQRFASLEALKQQIANDVVTARTFFGLKTPV

Specific function: Unknown

COG id: COG0196

COG function: function code H; FAD synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribF family [H]

Homologues:

Organism=Escherichia coli, GI1786208, Length=312, Percent_Identity=75.3205128205128, Blast_Score=482, Evalue=1e-137,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015864
- InterPro:   IPR015865
- InterPro:   IPR002606
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06574 FAD_syn; PF01687 Flavokinase [H]

EC number: =2.7.1.26; =2.7.7.2 [H]

Molecular weight: Translated: 34239; Mature: 34239

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELIRGIHNIRARHHGCVLTIGNFDGVHRGHQALLEQLKREGQRLGLPVMVMIFEPQPLE
CHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCE
LFAADKAPARLTRLRDKAKYLAQAGVDYLLCVKFDPRFAANTAQAFVAQLLVEKLGVKFL
EEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCEEE
TVGDDFRFGAGRQGDFQLLQQAGAEFGFDVISTDSFCDGGLRISSTAIRQALHDDDLVLA
EECCCCCCCCCCCCHHHHHHHCCHHCCCEEECCCCCCCCCCEEHHHHHHHHHCCCCHHHH
ETLLGHPYSISGRVVHGDELGRTIGFPTANLPLKRLVAPVKGVYAVDVYGLGSTPLYGVA
HHHHCCCCCCCCEEEECHHHCCCCCCCCCCCCHHHHHHHHCCEEEEEEEECCCCCCCEEE
NIGTRPTVAGVRQQLEVHLLDVTMDLYGCHIDVVLRAKLRNEQRFASLEALKQQIANDVV
CCCCCCHHHHHHHHHHEEEEEEEHHHHCCEEEEEEHHHHCCHHHHHHHHHHHHHHHHHHH
TARTFFGLKTPV
HHHHHHCCCCCC
>Mature Secondary Structure
MELIRGIHNIRARHHGCVLTIGNFDGVHRGHQALLEQLKREGQRLGLPVMVMIFEPQPLE
CHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCE
LFAADKAPARLTRLRDKAKYLAQAGVDYLLCVKFDPRFAANTAQAFVAQLLVEKLGVKFL
EEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCEEE
TVGDDFRFGAGRQGDFQLLQQAGAEFGFDVISTDSFCDGGLRISSTAIRQALHDDDLVLA
EECCCCCCCCCCCCHHHHHHHCCHHCCCEEECCCCCCCCCCEEHHHHHHHHHCCCCHHHH
ETLLGHPYSISGRVVHGDELGRTIGFPTANLPLKRLVAPVKGVYAVDVYGLGSTPLYGVA
HHHHCCCCCCCCEEEECHHHCCCCCCCCCCCCHHHHHHHHCCEEEEEEEECCCCCCCEEE
NIGTRPTVAGVRQQLEVHLLDVTMDLYGCHIDVVLRAKLRNEQRFASLEALKQQIANDVV
CCCCCCHHHHHHHHHHEEEEEEEHHHHCCEEEEEEHHHHCCHHHHHHHHHHHHHHHHHHH
TARTFFGLKTPV
HHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]