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The map label for this gene is ftsW [H]

Identifier: 22127501

GI number: 22127501

Start: 4020443

End: 4021645

Strand: Reverse

Name: ftsW [H]

Synonym: y3627

Alternate gene names: 22127501

Gene position: 4021645-4020443 (Counterclockwise)

Preceding gene: 22127502

Following gene: 22127500

Centisome position: 87.41

GC content: 50.46

Gene sequence:

>1203_bases
ATGCGTATGCCGGGGCTGGGGCTGTTTAATACCTTAAAACATTATGTCATGGGGTCGCGGGAGAGCGACACCACCAGCAT
GGTGCTTTATGACAGAACCTTGCTGTGGCTGACATTTGGTTTGGCGATTATTGGTTTTGTGATGGTGACGTCGGCGTCAA
TGCCAATCGGTCAGCGCTTGGCTAATGACCCTTTCCTGTTTGCTAAACGTGACGCGCTCTATCTGGCATTAGCGTTTGGT
TTGTCACTGGTGACGCTACGTATTCCGATGGATGTCTGGCAGCGCTATAGCAATATCATGTTATTGATTTCCATTGTTTT
GCTGCTCGTTGTTTTGGTGGTTGGTAGCTCGGTAAACGGGGCATCACGTTGGATTGCACTAGGGCCATTGCGTATCCAGC
CGGCCGAATTATCCAAGTTGTCTCTGTTTTGTTATTTGGCCAGCTATCTGGTGCGCAAGGTTGAAGAAGTCCGCAGTAAC
TTCTGGGGTTTTTGTAAACCCATGGGCGTGATGGTCATTCTGGCGGTGCTGTTGCTGGCCCAGCCCGATTTAGGAACGGT
GGTGGTGCTGTTTATCACCACGCTGGCGATGCTGTTCCTGGCAGGTGCCAAAATGTGGCAGTTTATGGCGATTATCGGTT
CTGGTGCCTTCGCGGTTTGTTTGCTGATTATCGCCGAGCCTTATCGTATGCGCCGCGTAACATCCTTCTGGAATCCGTGG
GCCGATCCCTTTGGCAGCGGCTATCAGTTAACCCAGTCACTGATGGCATTTGGCCGTGGTGAGTTTTGGGGGCAAGGTTT
AGGTAATTCAGTACAAAAACTGGAGTATTTACCGGAGGCGCACACCGATTTTATTTTCTCGATTTTAGGTGAAGAACTCG
GCTATTTCGGTGTGGTTTTGGCCCTGTTGATGGTATTCTTCGTCGCTTTTCGCGCGATGTCCATTGGCCGCCGTGCATTG
GAGATTGGTCAACGATTCTCTGGCTTTTTGGCTTGTTCAATTGGTATCTGGTTCAGTTTCCAGGCGCTGGTTAACGTTGG
TGCCGCTGCCGGAATGTTGCCGACGAAAGGCCTGACGTTGCCCCTGATAAGTTACGGTGGTTCAAGCCTGATAATTATGT
CAACGGCGATAGTGCTGTTGTTACGTATTGATTTTGAAACGCGGCTGGCAAAAGCCCAGGCGTTTGTAAGGAGTGCCCGA
TGA

Upstream 100 bases:

>100_bases
ATAGGGTGCTGCTGTCACCTGCGTGTGCCAGCCTGGATCAATTCCGCAGCTTTGAGCATCGTGGTAATGAGTTTGCTCGT
CTGGCAGAGGAGTTAGGCTG

Downstream 100 bases:

>100_bases
GTGGGAAGACCAAGCGTTTGATGGTGATGGCGGGTGGAACCGGGGGGCATGTCTTCCCCGGTTTGGCCGTGGCACATCAT
TTGATGGCGCAAGGCTGGCA

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MRMPGLGLFNTLKHYVMGSRESDTTSMVLYDRTLLWLTFGLAIIGFVMVTSASMPIGQRLANDPFLFAKRDALYLALAFG
LSLVTLRIPMDVWQRYSNIMLLISIVLLLVVLVVGSSVNGASRWIALGPLRIQPAELSKLSLFCYLASYLVRKVEEVRSN
FWGFCKPMGVMVILAVLLLAQPDLGTVVVLFITTLAMLFLAGAKMWQFMAIIGSGAFAVCLLIIAEPYRMRRVTSFWNPW
ADPFGSGYQLTQSLMAFGRGEFWGQGLGNSVQKLEYLPEAHTDFIFSILGEELGYFGVVLALLMVFFVAFRAMSIGRRAL
EIGQRFSGFLACSIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLIIMSTAIVLLLRIDFETRLAKAQAFVRSAR

Sequences:

>Translated_400_residues
MRMPGLGLFNTLKHYVMGSRESDTTSMVLYDRTLLWLTFGLAIIGFVMVTSASMPIGQRLANDPFLFAKRDALYLALAFG
LSLVTLRIPMDVWQRYSNIMLLISIVLLLVVLVVGSSVNGASRWIALGPLRIQPAELSKLSLFCYLASYLVRKVEEVRSN
FWGFCKPMGVMVILAVLLLAQPDLGTVVVLFITTLAMLFLAGAKMWQFMAIIGSGAFAVCLLIIAEPYRMRRVTSFWNPW
ADPFGSGYQLTQSLMAFGRGEFWGQGLGNSVQKLEYLPEAHTDFIFSILGEELGYFGVVLALLMVFFVAFRAMSIGRRAL
EIGQRFSGFLACSIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLIIMSTAIVLLLRIDFETRLAKAQAFVRSAR
>Mature_400_residues
MRMPGLGLFNTLKHYVMGSRESDTTSMVLYDRTLLWLTFGLAIIGFVMVTSASMPIGQRLANDPFLFAKRDALYLALAFG
LSLVTLRIPMDVWQRYSNIMLLISIVLLLVVLVVGSSVNGASRWIALGPLRIQPAELSKLSLFCYLASYLVRKVEEVRSN
FWGFCKPMGVMVILAVLLLAQPDLGTVVVLFITTLAMLFLAGAKMWQFMAIIGSGAFAVCLLIIAEPYRMRRVTSFWNPW
ADPFGSGYQLTQSLMAFGRGEFWGQGLGNSVQKLEYLPEAHTDFIFSILGEELGYFGVVLALLMVFFVAFRAMSIGRRAL
EIGQRFSGFLACSIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLIIMSTAIVLLLRIDFETRLAKAQAFVRSAR

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=403, Percent_Identity=80.6451612903226, Blast_Score=643, Evalue=0.0,
Organism=Escherichia coli, GI1786853, Length=333, Percent_Identity=32.1321321321321, Blast_Score=151, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 44166; Mature: 44166

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMPGLGLFNTLKHYVMGSRESDTTSMVLYDRTLLWLTFGLAIIGFVMVTSASMPIGQRL
CCCCCCCHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ANDPFLFAKRDALYLALAFGLSLVTLRIPMDVWQRYSNIMLLISIVLLLVVLVVGSSVNG
CCCCCEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ASRWIALGPLRIQPAELSKLSLFCYLASYLVRKVEEVRSNFWGFCKPMGVMVILAVLLLA
CCCEEEECCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QPDLGTVVVLFITTLAMLFLAGAKMWQFMAIIGSGAFAVCLLIIAEPYRMRRVTSFWNPW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCC
ADPFGSGYQLTQSLMAFGRGEFWGQGLGNSVQKLEYLPEAHTDFIFSILGEELGYFGVVL
CCCCCCHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ALLMVFFVAFRAMSIGRRALEIGQRFSGFLACSIGIWFSFQALVNVGAAAGMLPTKGLTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
PLISYGGSSLIIMSTAIVLLLRIDFETRLAKAQAFVRSAR
EHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRMPGLGLFNTLKHYVMGSRESDTTSMVLYDRTLLWLTFGLAIIGFVMVTSASMPIGQRL
CCCCCCCHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ANDPFLFAKRDALYLALAFGLSLVTLRIPMDVWQRYSNIMLLISIVLLLVVLVVGSSVNG
CCCCCEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ASRWIALGPLRIQPAELSKLSLFCYLASYLVRKVEEVRSNFWGFCKPMGVMVILAVLLLA
CCCEEEECCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QPDLGTVVVLFITTLAMLFLAGAKMWQFMAIIGSGAFAVCLLIIAEPYRMRRVTSFWNPW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCC
ADPFGSGYQLTQSLMAFGRGEFWGQGLGNSVQKLEYLPEAHTDFIFSILGEELGYFGVVL
CCCCCCHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ALLMVFFVAFRAMSIGRRALEIGQRFSGFLACSIGIWFSFQALVNVGAAAGMLPTKGLTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
PLISYGGSSLIIMSTAIVLLLRIDFETRLAKAQAFVRSAR
EHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]