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The map label for this gene is cyaE [H]

Identifier: 22127434

GI number: 22127434

Start: 3940611

End: 3942137

Strand: Direct

Name: cyaE [H]

Synonym: y3560

Alternate gene names: 22127434

Gene position: 3940611-3942137 (Clockwise)

Preceding gene: 22127433

Following gene: 22127436

Centisome position: 85.65

GC content: 52.19

Gene sequence:

>1527_bases
ATGATGACGCACGCAGTATTGACTGCCCGGATAGCCAAAATAAGCCTGACTTGCTCGATATTGAGTTGGAGCCTGTTGAT
CGTAGGTTGTGCTACAGATCGCTTGGATCTTGCACCTGCATCTTACACCGAACCCTGGACGCCAGATGGGAATGCAAGGG
CTTCCATGGGGGGCGGTAACTTTTCTGTGCCACCGAATCCGATCGTGGCCGAATTAGCCCAACCGCCGACCATAAAAAGT
GATCATGCTTATTCATTGCCAGAATTGATTGATATCGCCCAACGTCAGAATCCGGATACCCGCATTGCCTGGCAGCAAGC
GCGACAGGCAGCCCTTGCGGTAGGAATGGGGGAGGCGATATTTTTACCGATCATTTCTGCCAGTGTCATTGGTGGCTACC
AGCGTACGACCACACCTCTGCCTTATGCTATCGGCAACGAAAAGGATCTGAAAACAACCGGGAGCGCGGTTATTCCTGCT
TTGGCCTTACAGTGGCTTATCTTTGATTTCGGCCAGCGCAGCGCGTTGCTTGACGCCGCTAAACAGACGTCTTATGCCGC
TAATGTGACCTTCAATGGCATGCACCAGAAACTGATCTACGATGTGACACGCACTTACTTCCAATATGGTGCAGCACAAG
CCCAGAGCCAGATAGCAAAACAAACGTTGCAAAACAGTCTAAAGATTCAGGATGCTGCCGAGGAGCGCCAGAAAAAGGGT
ATTGCGACAACGGTTGAAGTGGCGTTGGCACGCCAGCAAGTCGCACAGTCTCAGTTGCGTCGTGTGGTGGCAAAAGGTAC
TGAACGTGATGCTTATCAGGCATTATTAGGGGCGATGGGTGTTTCTCCGTCATTGGATATCAAAGCCGCCTATACCGAAG
ATCGTGCTTTGCCGGATGGGATAAGCGCCCCGACAGAAAAGATGATCCAGTTGGCCCTCTCCCAGCGGCCAGATGTTTTA
GCCAGCTATGCGGCGGTCGAGGCAGCCAAGGCGGGTATCAAAGCCACTGAAGCCGATTTCTTGCCAAAAGTCTATCTGGC
CGGGGCGGTTGCTGGTGGTGATGGGCATTTTGATATTCAGGGCCTACCGGGTATCAGCCCGCAAACTTCATCCTCTAGCA
TTTTAGTCGGTGTCAGTGTTCCTCTGTACGATGGCGGGATACGCGCAGCCAGAGTTAAAGAGGCAGAATCCCGCGCTGCT
GTTGCTGCTGAAGGATTTAAGAAAACGCAGGAATTGGCGGTGCGCGAAATTGTGGTAGCAGCAGATACATTGCGCTCTGC
GCTCGAATCCAATCAGGCGGCATTAAATCTCGTGAAGACCTCGTTTATCTCCTATGATGCGGCGCTGGAGTCTTATCGCA
GTGGTGTTGGCACCATAACGGTCGCCAATGAGGCGGCAAATGGTTTGTTGAATGCTCAACAAATGAGTACTGATGCACAT
GCCGCCTCTTTGGTCGCCGCCGCCAATCTGGCTTTCGTCATGGGTAAAATGACCAACACCTCACCACCTTTGGAACTGCT
TCATTAG

Upstream 100 bases:

>100_bases
GGACAGAATAGCGGGTCTTTACGGCAAGAGTTATCACCTATTAATCTTACAATTCAACAACGTATAAAGCGGCTTGAGGA
ACTTCTAGGAATTTAATGAC

Downstream 100 bases:

>100_bases
AGAGTGAATGGCCCCAATTCCATTAGGTATCCTCTTACCTCTCAAAATGGGGCCTCTCTATTTTCAAACAGTGTAAAGAT
TTTCAAACAGCGTAAAATCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MMTHAVLTARIAKISLTCSILSWSLLIVGCATDRLDLAPASYTEPWTPDGNARASMGGGNFSVPPNPIVAELAQPPTIKS
DHAYSLPELIDIAQRQNPDTRIAWQQARQAALAVGMGEAIFLPIISASVIGGYQRTTTPLPYAIGNEKDLKTTGSAVIPA
LALQWLIFDFGQRSALLDAAKQTSYAANVTFNGMHQKLIYDVTRTYFQYGAAQAQSQIAKQTLQNSLKIQDAAEERQKKG
IATTVEVALARQQVAQSQLRRVVAKGTERDAYQALLGAMGVSPSLDIKAAYTEDRALPDGISAPTEKMIQLALSQRPDVL
ASYAAVEAAKAGIKATEADFLPKVYLAGAVAGGDGHFDIQGLPGISPQTSSSSILVGVSVPLYDGGIRAARVKEAESRAA
VAAEGFKKTQELAVREIVVAADTLRSALESNQAALNLVKTSFISYDAALESYRSGVGTITVANEAANGLLNAQQMSTDAH
AASLVAAANLAFVMGKMTNTSPPLELLH

Sequences:

>Translated_508_residues
MMTHAVLTARIAKISLTCSILSWSLLIVGCATDRLDLAPASYTEPWTPDGNARASMGGGNFSVPPNPIVAELAQPPTIKS
DHAYSLPELIDIAQRQNPDTRIAWQQARQAALAVGMGEAIFLPIISASVIGGYQRTTTPLPYAIGNEKDLKTTGSAVIPA
LALQWLIFDFGQRSALLDAAKQTSYAANVTFNGMHQKLIYDVTRTYFQYGAAQAQSQIAKQTLQNSLKIQDAAEERQKKG
IATTVEVALARQQVAQSQLRRVVAKGTERDAYQALLGAMGVSPSLDIKAAYTEDRALPDGISAPTEKMIQLALSQRPDVL
ASYAAVEAAKAGIKATEADFLPKVYLAGAVAGGDGHFDIQGLPGISPQTSSSSILVGVSVPLYDGGIRAARVKEAESRAA
VAAEGFKKTQELAVREIVVAADTLRSALESNQAALNLVKTSFISYDAALESYRSGVGTITVANEAANGLLNAQQMSTDAH
AASLVAAANLAFVMGKMTNTSPPLELLH
>Mature_508_residues
MMTHAVLTARIAKISLTCSILSWSLLIVGCATDRLDLAPASYTEPWTPDGNARASMGGGNFSVPPNPIVAELAQPPTIKS
DHAYSLPELIDIAQRQNPDTRIAWQQARQAALAVGMGEAIFLPIISASVIGGYQRTTTPLPYAIGNEKDLKTTGSAVIPA
LALQWLIFDFGQRSALLDAAKQTSYAANVTFNGMHQKLIYDVTRTYFQYGAAQAQSQIAKQTLQNSLKIQDAAEERQKKG
IATTVEVALARQQVAQSQLRRVVAKGTERDAYQALLGAMGVSPSLDIKAAYTEDRALPDGISAPTEKMIQLALSQRPDVL
ASYAAVEAAKAGIKATEADFLPKVYLAGAVAGGDGHFDIQGLPGISPQTSSSSILVGVSVPLYDGGIRAARVKEAESRAA
VAAEGFKKTQELAVREIVVAADTLRSALESNQAALNLVKTSFISYDAALESYRSGVGTITVANEAANGLLNAQQMSTDAH
AASLVAAANLAFVMGKMTNTSPPLELLH

Specific function: The outer membrane component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline. Is not involved in organic solven

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=270, Percent_Identity=25.9259259259259, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 53710; Mature: 53710

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTHAVLTARIAKISLTCSILSWSLLIVGCATDRLDLAPASYTEPWTPDGNARASMGGGN
CCCHHHHHHHHHHHHHHHHHHHEEHHEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCC
FSVPPNPIVAELAQPPTIKSDHAYSLPELIDIAQRQNPDTRIAWQQARQAALAVGMGEAI
CCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHH
FLPIISASVIGGYQRTTTPLPYAIGNEKDLKTTGSAVIPALALQWLIFDFGQRSALLDAA
HHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
KQTSYAANVTFNGMHQKLIYDVTRTYFQYGAAQAQSQIAKQTLQNSLKIQDAAEERQKKG
HHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
IATTVEVALARQQVAQSQLRRVVAKGTERDAYQALLGAMGVSPSLDIKAAYTEDRALPDG
CHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCC
ISAPTEKMIQLALSQRPDVLASYAAVEAAKAGIKATEADFLPKVYLAGAVAGGDGHFDIQ
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHEEEECCCCCEEEC
GLPGISPQTSSSSILVGVSVPLYDGGIRAARVKEAESRAAVAAEGFKKTQELAVREIVVA
CCCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADTLRSALESNQAALNLVKTSFISYDAALESYRSGVGTITVANEAANGLLNAQQMSTDAH
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHCCCCCHHHHCCHHH
AASLVAAANLAFVMGKMTNTSPPLELLH
HHHHHHHHHHHHHHHHCCCCCCCHHHCC
>Mature Secondary Structure
MMTHAVLTARIAKISLTCSILSWSLLIVGCATDRLDLAPASYTEPWTPDGNARASMGGGN
CCCHHHHHHHHHHHHHHHHHHHEEHHEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCC
FSVPPNPIVAELAQPPTIKSDHAYSLPELIDIAQRQNPDTRIAWQQARQAALAVGMGEAI
CCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHH
FLPIISASVIGGYQRTTTPLPYAIGNEKDLKTTGSAVIPALALQWLIFDFGQRSALLDAA
HHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
KQTSYAANVTFNGMHQKLIYDVTRTYFQYGAAQAQSQIAKQTLQNSLKIQDAAEERQKKG
HHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
IATTVEVALARQQVAQSQLRRVVAKGTERDAYQALLGAMGVSPSLDIKAAYTEDRALPDG
CHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCC
ISAPTEKMIQLALSQRPDVLASYAAVEAAKAGIKATEADFLPKVYLAGAVAGGDGHFDIQ
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHEEEECCCCCEEEC
GLPGISPQTSSSSILVGVSVPLYDGGIRAARVKEAESRAAVAAEGFKKTQELAVREIVVA
CCCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADTLRSALESNQAALNLVKTSFISYDAALESYRSGVGTITVANEAANGLLNAQQMSTDAH
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHCCCCCHHHHCCHHH
AASLVAAANLAFVMGKMTNTSPPLELLH
HHHHHHHHHHHHHHHHCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11160799 [H]