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The map label for this gene is fepB [H]

Identifier: 22127351

GI number: 22127351

Start: 3859173

End: 3860252

Strand: Direct

Name: fepB [H]

Synonym: y3477

Alternate gene names: 22127351

Gene position: 3859173-3860252 (Clockwise)

Preceding gene: 22127349

Following gene: 22127356

Centisome position: 83.88

GC content: 46.39

Gene sequence:

>1080_bases
ATGTTCCTTTATATGACCTATATTGAGCGTAAAATACGCCACTCTCTGTTTATTAGTCTCGGCTGTTTGGGTCTTATTTT
ATCTCTTTCCGGCTGCGAACCCGCAGAGGAAACCAACTTCCATCCATTCCCTATCGATGAGAATCACAGTACATCATCGC
CGTGGTCCCGTACCGTAGACACAGTGAAAGGCCCGGTGACACTCACCCATAAGCCAGCCCGTATCGTCTCCACCAGCATC
ACCATTACGGGTACCTTGCTGGCAATAAATGCACCTATCATTGCCAGTAGTGCTACCGAACCCAATACGACGCTAGCCGA
TAATAAAGGATTCTTTACTCAATGGTCGGATATTGCACGGGCCCGTCACTTAATCCCGATGTACCAGACCGAACCCAATA
TTAAAGCTGTCGCTAAGATGCGGCCAGACTTAATTATTATTTCCGCCACTGGTGACGATTCCACATTGGAATTGTACGAT
CAACTGTCGGCCATCGCCCCGACATTGGTGATTAATTACGATGATAAGAGTTGGCAAGAACTGACACTACAATTAGGCCA
GGCGACGGGCCATGAAGGGGATGCCGAACAGGTGATTGATAAATTTGCCCGCCGACTCAATGAAGTAAAACAGAAAATAA
CCCTACCACCGCAACCCGTTTCAGCATTTGTCTATCAGGAGGTGAGTGGTAGCGCCAAACTGTGGACGGAAAATTCCGCA
CAGGGAAGATTGTTATTGGAGCTGGGTTTCACGCTGGCCAATGTGCCAGACACGCTGAAGGACAACACCCATACAGAGCA
CCGTAAAGATATCATTCAGTTAGGTGGAGATGAGCTAGCACAGGGCCTGAACGGTAAGACTATTTTACTCTTTTCTGGCG
TTCATTCTGCAATTGACGCATTGAAAAGTAATAAGTTTTTAACCAATCTTCCAGCGATTCAGCACGATAACGTTTATGCG
GCAGGTTATGATACTTTCCGGTTAGATTACTACAGTGCGAATAATTTGTTGACGCGAATTGAGTCAATGTTTAAGGGAAA
AAAGGACAGCGAACCCACCTATCATGAGAGCAGAACCTAA

Upstream 100 bases:

>100_bases
ACATTGTCATATTATCATTCGATACAAATATCATTATTGGTAAATTTTATTGATATATTTGCTGATTTACCCTCACCAAA
GAGAAGGATAAAACACCGCT

Downstream 100 bases:

>100_bases
CGGCATAAAAAGCGACACTTATTGGTCGCTTGAGGTTATTGACAACGCTATTCTTAGCCTCGTGAGTGAAGGGTTGACCG
CACCTAGGGGCACTTCGGTG

Product: iron-enterobactin transporter periplasmic binding protein

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MFLYMTYIERKIRHSLFISLGCLGLILSLSGCEPAEETNFHPFPIDENHSTSSPWSRTVDTVKGPVTLTHKPARIVSTSI
TITGTLLAINAPIIASSATEPNTTLADNKGFFTQWSDIARARHLIPMYQTEPNIKAVAKMRPDLIIISATGDDSTLELYD
QLSAIAPTLVINYDDKSWQELTLQLGQATGHEGDAEQVIDKFARRLNEVKQKITLPPQPVSAFVYQEVSGSAKLWTENSA
QGRLLLELGFTLANVPDTLKDNTHTEHRKDIIQLGGDELAQGLNGKTILLFSGVHSAIDALKSNKFLTNLPAIQHDNVYA
AGYDTFRLDYYSANNLLTRIESMFKGKKDSEPTYHESRT

Sequences:

>Translated_359_residues
MFLYMTYIERKIRHSLFISLGCLGLILSLSGCEPAEETNFHPFPIDENHSTSSPWSRTVDTVKGPVTLTHKPARIVSTSI
TITGTLLAINAPIIASSATEPNTTLADNKGFFTQWSDIARARHLIPMYQTEPNIKAVAKMRPDLIIISATGDDSTLELYD
QLSAIAPTLVINYDDKSWQELTLQLGQATGHEGDAEQVIDKFARRLNEVKQKITLPPQPVSAFVYQEVSGSAKLWTENSA
QGRLLLELGFTLANVPDTLKDNTHTEHRKDIIQLGGDELAQGLNGKTILLFSGVHSAIDALKSNKFLTNLPAIQHDNVYA
AGYDTFRLDYYSANNLLTRIESMFKGKKDSEPTYHESRT
>Mature_359_residues
MFLYMTYIERKIRHSLFISLGCLGLILSLSGCEPAEETNFHPFPIDENHSTSSPWSRTVDTVKGPVTLTHKPARIVSTSI
TITGTLLAINAPIIASSATEPNTTLADNKGFFTQWSDIARARHLIPMYQTEPNIKAVAKMRPDLIIISATGDDSTLELYD
QLSAIAPTLVINYDDKSWQELTLQLGQATGHEGDAEQVIDKFARRLNEVKQKITLPPQPVSAFVYQEVSGSAKLWTENSA
QGRLLLELGFTLANVPDTLKDNTHTEHRKDIIQLGGDELAQGLNGKTILLFSGVHSAIDALKSNKFLTNLPAIQHDNVYA
AGYDTFRLDYYSANNLLTRIESMFKGKKDSEPTYHESRT

Specific function: Binds ferrienterobactin; part of the binding-protein- dependent transport system for uptake of ferrienterobactin [H]

COG id: COG4592

COG function: function code P; ABC-type Fe2+-enterobactin transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe/B12 periplasmic-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786807, Length=293, Percent_Identity=53.9249146757679, Blast_Score=325, Evalue=2e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002491 [H]

Pfam domain/function: PF01497 Peripla_BP_2 [H]

EC number: NA

Molecular weight: Translated: 39821; Mature: 39821

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS50983 FE_B12_PBP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLYMTYIERKIRHSLFISLGCLGLILSLSGCEPAEETNFHPFPIDENHSTSSPWSRTVD
CEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHH
TVKGPVTLTHKPARIVSTSITITGTLLAINAPIIASSATEPNTTLADNKGFFTQWSDIAR
HCCCCEEEECCCCEEEEEEEEEEEEEEEEECCEEECCCCCCCCEECCCCCCCHHHHHHHH
ARHLIPMYQTEPNIKAVAKMRPDLIIISATGDDSTLELYDQLSAIAPTLVINYDDKSWQE
HHHCCCCCCCCCCHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCHHH
LTLQLGQATGHEGDAEQVIDKFARRLNEVKQKITLPPQPVSAFVYQEVSGSAKLWTENSA
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCCC
QGRLLLELGFTLANVPDTLKDNTHTEHRKDIIQLGGDELAQGLNGKTILLFSGVHSAIDA
CCEEEEEECCHHHCCCCHHCCCCCHHHHHHHHHCCCHHHHCCCCCCEEEEECCHHHHHHH
LKSNKFLTNLPAIQHDNVYAAGYDTFRLDYYSANNLLTRIESMFKGKKDSEPTYHESRT
HHCCCEEECCCCEECCCEEEECCCEEEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFLYMTYIERKIRHSLFISLGCLGLILSLSGCEPAEETNFHPFPIDENHSTSSPWSRTVD
CEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHH
TVKGPVTLTHKPARIVSTSITITGTLLAINAPIIASSATEPNTTLADNKGFFTQWSDIAR
HCCCCEEEECCCCEEEEEEEEEEEEEEEEECCEEECCCCCCCCEECCCCCCCHHHHHHHH
ARHLIPMYQTEPNIKAVAKMRPDLIIISATGDDSTLELYDQLSAIAPTLVINYDDKSWQE
HHHCCCCCCCCCCHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCHHH
LTLQLGQATGHEGDAEQVIDKFARRLNEVKQKITLPPQPVSAFVYQEVSGSAKLWTENSA
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCCC
QGRLLLELGFTLANVPDTLKDNTHTEHRKDIIQLGGDELAQGLNGKTILLFSGVHSAIDA
CCEEEEEECCHHHCCCCHHCCCCCHHHHHHHHHCCCHHHHCCCCCCEEEEECCHHHHHHH
LKSNKFLTNLPAIQHDNVYAAGYDTFRLDYYSANNLLTRIESMFKGKKDSEPTYHESRT
HHCCCEEECCCCEECCCEEEECCCEEEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]