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The map label for this gene is mycA [H]

Identifier: 22127281

GI number: 22127281

Start: 3770663

End: 3774076

Strand: Direct

Name: mycA [H]

Synonym: y3406

Alternate gene names: 22127281

Gene position: 3770663-3774076 (Clockwise)

Preceding gene: 22127280

Following gene: 22127283

Centisome position: 81.96

GC content: 46.34

Gene sequence:

>3414_bases
ATGAATTTATTAAATAATGAAACTCGTTGGGTGAGGGAGGCGTTATTTGAACAGGCAACAAAGTCCAAATATGATGTCGC
ATTGCGTTATTGTGATAAAGATGATGTAGATTCTTACTCTTATAGCCAACTGATATCACTGGGCTATTCGTTAGCTACAC
AGATTGAAATAGAAAACAATCCGCCTGGGCCTGCTATTCTGCTCATGCCAGGAGGCTCGCTTTTTGTCATAAGCTTTATC
GCTTGTATTATTAGGGGGGTGCCGGCTGTCCCTGTGCATCTAACCAATCATTTTAAATTGGGTCGCAGTATTGATACCTT
GTCCCATATTTTGGCTGATAGCCATGGTGAATATATATTCACCTTAAGTTCGTTATCCGACGAAATTAAAAAACAAGGTT
GGCATCGTACACATCAGATTGTTTTTGTTGATCAACAACTCACCGGTAGTCGTCGCTATTTCCCCACGAAAAAAAATTAT
GATGCACTTTATTATCCCAGTCATTTACCTGTGTATCTGCAATATTCTTCTGGTTCCACAGCAAAGCCAAAAGCGGTATG
TAATTACGATCATAATATGCGGGTGCAACATCATATCTTGCTTGAATTACATCTGCATTGTCAGCCAAAAATCATCACCG
CGAACTGGCTGCCTTTTTATCATGATTTAGGCATGTTCAGCGGTTTGTTATTGCCATTGTTATCCGGTGGTTGCTGTAAT
TTCATGCCTTCTGTGCACTTTATTACAGAGCCATTTCGTTGGCTGAAAATGATTAATGATTATCAGGCTAACTCCGGGGC
TGCCCCCGATTTTGCGTGGGATTTGTGTACCACAATGGTGACGGACGAACACATTTGCCAGTTGGATCTCTCCTCCATCA
AGATGGCAATGAATGGGGCTGAACCCATTCGCCCAGAGACAATGGCAAATTTTGCGGCCCGTTTTGCATCCACAGGTTTT
GATGCCCACAGTTTCACGCCCGGTTATGGGATGGCCGAAGCAACTCTGACCGTAAGCCATAAGCCTATCGATACTGATTA
CTGCTGTTTGGCATTTAACCCAATGGCATTAGCGGCAGGTAAAGCCATTTTAGATCCGCAAGGGTGTCGGTTGGTAAGCT
CAGGGCATGTGGTTAGAGCATGGCAATTGCAGATTGTTGATCCCCAGACATGTCAGCCCTTGCCTGAGGCGAACATTGGG
GAAGTCTGGGTTCGAGGCGGTTCTGTGGCGGGGGGGTATTGGCAGCAGCCCGAACTCACAAAAGCCACTTTCCACAATAC
ACTGGCAGGTAACTCTCACCATGATTATTTACGTACGGGGGATCTTGCCTTTGTGTATCAAGGGGAACTCTTTATTTGTG
GGCGATTAAAAGATCTCATTATTGTGGCTGGGCAAAATTATATGCCCAAGGATATTGAAACAGCAATTGAGTACGCCTGC
GATGATATCCACACGGGGGGAGTGTGTGTGTGTCAGCATTTTGACAGCGGCGAATTTATTGTGATGGCCGAGGTCTATCG
TCATTTAACATCAACGGCACTTCAGCGTATTGCTCAGCAGATTGTGGCGACTGTAGCCCGCCATTTTCAACTGAAATCTG
ACAAGGTCATCTTACTCGCCCGTGGAAAGCTCTTAAAAACATCGAGTGGCAAGATCCGCCGCAGTCATATGCTTTCTCTC
TATTTCACGCAACAATTGAGCGCGCTTTATGTACAGGAGTCACAGAGAAAGACTCAAGATGAAATGTTATTTGATCAAGA
AAGCGTGTTATTTGAGCAAGAGGCCATACTGTTTGATTGGCTCCATAAAACAGGGTGTGAATTACTCGGTTGCGAGGCGA
TCAATCCTGATAGTGGGCTACATCAGGCAGGGTTAACCAGTTTGTTAGCGATACAATTTTGTCAGAGTATTAATCATTTT
CTGGGCTGTCATCTCAATGTCGCAGATCTCTTCGCCTATCCTACATTACGGCAACTGACCTTATTTTTATCTCAGCACCA
AGAAGATATCGCCTCCTCAAGTTCAACGGAAGCAGGAGATGATCGGGATGTCGCGATTGTGGCTATCAGTTGTCGCTTAC
CGGGGCAGGTGGGGGTGAGCTGGGCGGACTATTGCACAGAATTATCCGCAGGTAACAGCGCGGTACGTCATGAAAAAAAT
CGACTGCGACACTGTGTTTTACCGATAGGCGCATTAGAAGATATTGATCAGTTCGACGCTGCTTTCTTTAATATCAGCGA
ACGAGAAGCCATCTTACTCGATCCACAACAGCGTCATATTTTAGAGCTGAGTTGGCACCTGTTTGAGCAGGCGGGTTGGC
AACCTGAACAATTGAAACAAGGCGATATTGGTTTTTACATTGGTCAAAGTGGCAGCGAATATGGGCAAATGTTGTTACAG
AAAAATGACCCCGATTATGCCAAAAGTTATCTGGCGACGGGGATTTGTAGCAGTGCGACATCTGGGCGGTTGGCGAAATT
CTATGGCACTCGTGGCCCGGCATTAACCATTGATACCGCTTGTTCTTCTTCGCTGGTCGCACTGGATAGCGCGATGTTGT
CACTACAGCAAAAACAGTGCAGCGCGGCTGTCGTGGGGGGCGTGAATTTACTCCTATCGGCACAAATAGAACAAACTCTT
ATCAATGCGGGTATGTTATCACCCAAGGGGCACTGTGCTACGTTCAGTGATGATGCTGATGGCTATGCCCGAGGAGAAGG
GGCGGTATTATTCCTGTTAAAACCTTATCGTCAGGCCGTGATAGATGGCGATCCTGTCTTAGCGATCATTGAGGGCAGTG
TCGTTGCGCAGGATGGTGAGAGCAGCAGCCTGACGGCACCGAATCCACACGCTCAAGCGGCTATGATGTCGCAGCTTTTA
CAGCGAGCATCATTGGCTCCCGATGATATCTCGTTATTGGAAACCCATGGAACGGGTACTTCGTTAGGGGATCCCGTTGA
GCTAAGCGCCATTGATCGTGTCTATGGTCAACGAAAAACGCCATTACGTTTAGGGGCGAGTAAAAGTCAGGTTGGGCACT
TGGAGGCCGCTGCGGGGGGATTTGCATTAGCCAGGGCTGTCGCGCAGATACAACAACAGAAGGCCTTTGGTCACCCCACG
CTAAATAGCTATAACCCACTGATAGCAGAAAAATTATCACGTTATTATTTCGATAAAGATACCTGCCCTTGGGTAATCAA
ACGTGTCGCCATCAATGCTTTTAGCTTTACCGGAACGATGGCTGCGGCCGTGTTGAGAAAGCCTACGGCAGTTGCTAGAT
CAATAAAGTCAATTACATCAATAAAGTCAGCCACATCAATAAAATCAGTTACATCAATAAATGTAACGAACGGTGCAATA
GTGATCCACACCCAACGCCTGAAATCAGATCCAGGGGGTAATCTGCTCTCCTGA

Upstream 100 bases:

>100_bases
AATTTTGGTGTAAAAGAGCTATGTCCTGTGGGCACTTTATGTTTATGCATAGAGTCGTTGATTTATCAAAAGTGATCTAT
ATGCAACTACAGGTAATGGT

Downstream 100 bases:

>100_bases
TTCAGGAGAGTTTATGGTCACTTTTGAGACAGTTATGGAAATTAAAATCCTGCACAAGCAGGGAATGAGTAGCCGGGCGA
TTGCCAGAGAACTGGGGATC

Product: nonribosomal peptide synthetase/polyketide synthase

Products: AMP; diphosphate +an acyl-CoA [C]

Alternate protein names: Glutamate-1-semialdehyde aminotransferase; GSA-AT; ATP-dependent asparagine adenylase 1; AsnA 1; Asparagine activase 1 [H]

Number of amino acids: Translated: 1137; Mature: 1137

Protein sequence:

>1137_residues
MNLLNNETRWVREALFEQATKSKYDVALRYCDKDDVDSYSYSQLISLGYSLATQIEIENNPPGPAILLMPGGSLFVISFI
ACIIRGVPAVPVHLTNHFKLGRSIDTLSHILADSHGEYIFTLSSLSDEIKKQGWHRTHQIVFVDQQLTGSRRYFPTKKNY
DALYYPSHLPVYLQYSSGSTAKPKAVCNYDHNMRVQHHILLELHLHCQPKIITANWLPFYHDLGMFSGLLLPLLSGGCCN
FMPSVHFITEPFRWLKMINDYQANSGAAPDFAWDLCTTMVTDEHICQLDLSSIKMAMNGAEPIRPETMANFAARFASTGF
DAHSFTPGYGMAEATLTVSHKPIDTDYCCLAFNPMALAAGKAILDPQGCRLVSSGHVVRAWQLQIVDPQTCQPLPEANIG
EVWVRGGSVAGGYWQQPELTKATFHNTLAGNSHHDYLRTGDLAFVYQGELFICGRLKDLIIVAGQNYMPKDIETAIEYAC
DDIHTGGVCVCQHFDSGEFIVMAEVYRHLTSTALQRIAQQIVATVARHFQLKSDKVILLARGKLLKTSSGKIRRSHMLSL
YFTQQLSALYVQESQRKTQDEMLFDQESVLFEQEAILFDWLHKTGCELLGCEAINPDSGLHQAGLTSLLAIQFCQSINHF
LGCHLNVADLFAYPTLRQLTLFLSQHQEDIASSSSTEAGDDRDVAIVAISCRLPGQVGVSWADYCTELSAGNSAVRHEKN
RLRHCVLPIGALEDIDQFDAAFFNISEREAILLDPQQRHILELSWHLFEQAGWQPEQLKQGDIGFYIGQSGSEYGQMLLQ
KNDPDYAKSYLATGICSSATSGRLAKFYGTRGPALTIDTACSSSLVALDSAMLSLQQKQCSAAVVGGVNLLLSAQIEQTL
INAGMLSPKGHCATFSDDADGYARGEGAVLFLLKPYRQAVIDGDPVLAIIEGSVVAQDGESSSLTAPNPHAQAAMMSQLL
QRASLAPDDISLLETHGTGTSLGDPVELSAIDRVYGQRKTPLRLGASKSQVGHLEAAAGGFALARAVAQIQQQKAFGHPT
LNSYNPLIAEKLSRYYFDKDTCPWVIKRVAINAFSFTGTMAAAVLRKPTAVARSIKSITSIKSATSIKSVTSINVTNGAI
VIHTQRLKSDPGGNLLS

Sequences:

>Translated_1137_residues
MNLLNNETRWVREALFEQATKSKYDVALRYCDKDDVDSYSYSQLISLGYSLATQIEIENNPPGPAILLMPGGSLFVISFI
ACIIRGVPAVPVHLTNHFKLGRSIDTLSHILADSHGEYIFTLSSLSDEIKKQGWHRTHQIVFVDQQLTGSRRYFPTKKNY
DALYYPSHLPVYLQYSSGSTAKPKAVCNYDHNMRVQHHILLELHLHCQPKIITANWLPFYHDLGMFSGLLLPLLSGGCCN
FMPSVHFITEPFRWLKMINDYQANSGAAPDFAWDLCTTMVTDEHICQLDLSSIKMAMNGAEPIRPETMANFAARFASTGF
DAHSFTPGYGMAEATLTVSHKPIDTDYCCLAFNPMALAAGKAILDPQGCRLVSSGHVVRAWQLQIVDPQTCQPLPEANIG
EVWVRGGSVAGGYWQQPELTKATFHNTLAGNSHHDYLRTGDLAFVYQGELFICGRLKDLIIVAGQNYMPKDIETAIEYAC
DDIHTGGVCVCQHFDSGEFIVMAEVYRHLTSTALQRIAQQIVATVARHFQLKSDKVILLARGKLLKTSSGKIRRSHMLSL
YFTQQLSALYVQESQRKTQDEMLFDQESVLFEQEAILFDWLHKTGCELLGCEAINPDSGLHQAGLTSLLAIQFCQSINHF
LGCHLNVADLFAYPTLRQLTLFLSQHQEDIASSSSTEAGDDRDVAIVAISCRLPGQVGVSWADYCTELSAGNSAVRHEKN
RLRHCVLPIGALEDIDQFDAAFFNISEREAILLDPQQRHILELSWHLFEQAGWQPEQLKQGDIGFYIGQSGSEYGQMLLQ
KNDPDYAKSYLATGICSSATSGRLAKFYGTRGPALTIDTACSSSLVALDSAMLSLQQKQCSAAVVGGVNLLLSAQIEQTL
INAGMLSPKGHCATFSDDADGYARGEGAVLFLLKPYRQAVIDGDPVLAIIEGSVVAQDGESSSLTAPNPHAQAAMMSQLL
QRASLAPDDISLLETHGTGTSLGDPVELSAIDRVYGQRKTPLRLGASKSQVGHLEAAAGGFALARAVAQIQQQKAFGHPT
LNSYNPLIAEKLSRYYFDKDTCPWVIKRVAINAFSFTGTMAAAVLRKPTAVARSIKSITSIKSATSIKSVTSINVTNGAI
VIHTQRLKSDPGGNLLS
>Mature_1137_residues
MNLLNNETRWVREALFEQATKSKYDVALRYCDKDDVDSYSYSQLISLGYSLATQIEIENNPPGPAILLMPGGSLFVISFI
ACIIRGVPAVPVHLTNHFKLGRSIDTLSHILADSHGEYIFTLSSLSDEIKKQGWHRTHQIVFVDQQLTGSRRYFPTKKNY
DALYYPSHLPVYLQYSSGSTAKPKAVCNYDHNMRVQHHILLELHLHCQPKIITANWLPFYHDLGMFSGLLLPLLSGGCCN
FMPSVHFITEPFRWLKMINDYQANSGAAPDFAWDLCTTMVTDEHICQLDLSSIKMAMNGAEPIRPETMANFAARFASTGF
DAHSFTPGYGMAEATLTVSHKPIDTDYCCLAFNPMALAAGKAILDPQGCRLVSSGHVVRAWQLQIVDPQTCQPLPEANIG
EVWVRGGSVAGGYWQQPELTKATFHNTLAGNSHHDYLRTGDLAFVYQGELFICGRLKDLIIVAGQNYMPKDIETAIEYAC
DDIHTGGVCVCQHFDSGEFIVMAEVYRHLTSTALQRIAQQIVATVARHFQLKSDKVILLARGKLLKTSSGKIRRSHMLSL
YFTQQLSALYVQESQRKTQDEMLFDQESVLFEQEAILFDWLHKTGCELLGCEAINPDSGLHQAGLTSLLAIQFCQSINHF
LGCHLNVADLFAYPTLRQLTLFLSQHQEDIASSSSTEAGDDRDVAIVAISCRLPGQVGVSWADYCTELSAGNSAVRHEKN
RLRHCVLPIGALEDIDQFDAAFFNISEREAILLDPQQRHILELSWHLFEQAGWQPEQLKQGDIGFYIGQSGSEYGQMLLQ
KNDPDYAKSYLATGICSSATSGRLAKFYGTRGPALTIDTACSSSLVALDSAMLSLQQKQCSAAVVGGVNLLLSAQIEQTL
INAGMLSPKGHCATFSDDADGYARGEGAVLFLLKPYRQAVIDGDPVLAIIEGSVVAQDGESSSLTAPNPHAQAAMMSQLL
QRASLAPDDISLLETHGTGTSLGDPVELSAIDRVYGQRKTPLRLGASKSQVGHLEAAAGGFALARAVAQIQQQKAFGHPT
LNSYNPLIAEKLSRYYFDKDTCPWVIKRVAINAFSFTGTMAAAVLRKPTAVARSIKSITSIKSATSIKSVTSINVTNGAI
VIHTQRLKSDPGGNLLS

Specific function: This protein is a multifunctional enzyme, able to activate a long chain fatty acid and link it with the amino acid Asn as part of the synthesis of mycosubtilin. The activation sites consist of individual domains [H]

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Partially Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI41872631, Length=414, Percent_Identity=33.8164251207729, Blast_Score=212, Evalue=2e-54,
Organism=Homo sapiens, GI8923559, Length=335, Percent_Identity=26.865671641791, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI55749758, Length=546, Percent_Identity=22.3443223443223, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI225735629, Length=540, Percent_Identity=21.2962962962963, Blast_Score=73, Evalue=2e-12,
Organism=Homo sapiens, GI45827692, Length=540, Percent_Identity=21.2962962962963, Blast_Score=73, Evalue=2e-12,
Organism=Homo sapiens, GI44888818, Length=536, Percent_Identity=21.455223880597, Blast_Score=72, Evalue=4e-12,
Organism=Escherichia coli, GI1788107, Length=394, Percent_Identity=25.6345177664975, Blast_Score=78, Evalue=4e-15,
Organism=Escherichia coli, GI1787337, Length=306, Percent_Identity=23.8562091503268, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI212642053, Length=422, Percent_Identity=32.2274881516588, Blast_Score=211, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17550940, Length=531, Percent_Identity=29.9435028248588, Blast_Score=187, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI17531443, Length=427, Percent_Identity=23.6533957845433, Blast_Score=91, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17559526, Length=403, Percent_Identity=26.302729528536, Blast_Score=89, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320904, Length=315, Percent_Identity=23.8095238095238, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581345, Length=455, Percent_Identity=30.3296703296703, Blast_Score=189, Evalue=9e-48,
Organism=Drosophila melanogaster, GI221330659, Length=421, Percent_Identity=31.353919239905, Blast_Score=183, Evalue=5e-46,
Organism=Drosophila melanogaster, GI19920632, Length=421, Percent_Identity=31.353919239905, Blast_Score=183, Evalue=6e-46,
Organism=Drosophila melanogaster, GI24644341, Length=286, Percent_Identity=27.6223776223776, Blast_Score=89, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR005814
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00202 Aminotran_3; PF00501 AMP-binding; PF00668 Condensation; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF00550 PP-binding [H]

EC number: 6.2.1.3 [C]

Molecular weight: Translated: 124823; Mature: 124823

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS50075 ACP_DOMAIN ; PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLNNETRWVREALFEQATKSKYDVALRYCDKDDVDSYSYSQLISLGYSLATQIEIENN
CCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHCCCEEEEEEECCC
PPGPAILLMPGGSLFVISFIACIIRGVPAVPVHLTNHFKLGRSIDTLSHILADSHGEYIF
CCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEECCCEECCCHHHHHHHHHHCCCCCEEE
TLSSLSDEIKKQGWHRTHQIVFVDQQLTGSRRYFPTKKNYDALYYPSHLPVYLQYSSGST
EHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCCC
AKPKAVCNYDHNMRVQHHILLELHLHCQPKIITANWLPFYHDLGMFSGLLLPLLSGGCCN
CCCCEEECCCCCCEEEEEEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHH
FMPSVHFITEPFRWLKMINDYQANSGAAPDFAWDLCTTMVTDEHICQLDLSSIKMAMNGA
HCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
EPIRPETMANFAARFASTGFDAHSFTPGYGMAEATLTVSHKPIDTDYCCLAFNPMALAAG
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEECCHHHHCC
KAILDPQGCRLVSSGHVVRAWQLQIVDPQTCQPLPEANIGEVWVRGGSVAGGYWQQPELT
CEEECCCCCEEECCCCEEEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCH
KATFHNTLAGNSHHDYLRTGDLAFVYQGELFICGRLKDLIIVAGQNYMPKDIETAIEYAC
HHHHHHHCCCCCCCCCEEECCEEEEEECCEEEEECCCEEEEECCCCCCCHHHHHHHHHHH
DDIHTGGVCVCQHFDSGEFIVMAEVYRHLTSTALQRIAQQIVATVARHFQLKSDKVILLA
HCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
RGKLLKTSSGKIRRSHMLSLYFTQQLSALYVQESQRKTQDEMLFDQESVLFEQEAILFDW
CCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
LHKTGCELLGCEAINPDSGLHQAGLTSLLAIQFCQSINHFLGCHLNVADLFAYPTLRQLT
HHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHH
LFLSQHQEDIASSSSTEAGDDRDVAIVAISCRLPGQVGVSWADYCTELSAGNSAVRHEKN
HHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHH
RLRHCVLPIGALEDIDQFDAAFFNISEREAILLDPQQRHILELSWHLFEQAGWQPEQLKQ
HHHEEEECCCCHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCHHHHCC
GDIGFYIGQSGSEYGQMLLQKNDPDYAKSYLATGICSSATSGRLAKFYGTRGPALTIDTA
CCCEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEEECC
CSSSLVALDSAMLSLQQKQCSAAVVGGVNLLLSAQIEQTLINAGMLSPKGHCATFSDDAD
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCC
GYARGEGAVLFLLKPYRQAVIDGDPVLAIIEGSVVAQDGESSSLTAPNPHAQAAMMSQLL
CCCCCCCEEEEEEEHHHHHHCCCCCEEEEEECCEEECCCCCCCCCCCCCHHHHHHHHHHH
QRASLAPDDISLLETHGTGTSLGDPVELSAIDRVYGQRKTPLRLGASKSQVGHLEAAAGG
HHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHCCH
FALARAVAQIQQQKAFGHPTLNSYNPLIAEKLSRYYFDKDTCPWVIKRVAINAFSFTGTM
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
AAAVLRKPTAVARSIKSITSIKSATSIKSVTSINVTNGAIVIHTQRLKSDPGGNLLS
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEEHHHCCCCCCCCCC
>Mature Secondary Structure
MNLLNNETRWVREALFEQATKSKYDVALRYCDKDDVDSYSYSQLISLGYSLATQIEIENN
CCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHCCCEEEEEEECCC
PPGPAILLMPGGSLFVISFIACIIRGVPAVPVHLTNHFKLGRSIDTLSHILADSHGEYIF
CCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEECCCEECCCHHHHHHHHHHCCCCCEEE
TLSSLSDEIKKQGWHRTHQIVFVDQQLTGSRRYFPTKKNYDALYYPSHLPVYLQYSSGST
EHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCCC
AKPKAVCNYDHNMRVQHHILLELHLHCQPKIITANWLPFYHDLGMFSGLLLPLLSGGCCN
CCCCEEECCCCCCEEEEEEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHH
FMPSVHFITEPFRWLKMINDYQANSGAAPDFAWDLCTTMVTDEHICQLDLSSIKMAMNGA
HCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
EPIRPETMANFAARFASTGFDAHSFTPGYGMAEATLTVSHKPIDTDYCCLAFNPMALAAG
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEECCHHHHCC
KAILDPQGCRLVSSGHVVRAWQLQIVDPQTCQPLPEANIGEVWVRGGSVAGGYWQQPELT
CEEECCCCCEEECCCCEEEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCH
KATFHNTLAGNSHHDYLRTGDLAFVYQGELFICGRLKDLIIVAGQNYMPKDIETAIEYAC
HHHHHHHCCCCCCCCCEEECCEEEEEECCEEEEECCCEEEEECCCCCCCHHHHHHHHHHH
DDIHTGGVCVCQHFDSGEFIVMAEVYRHLTSTALQRIAQQIVATVARHFQLKSDKVILLA
HCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
RGKLLKTSSGKIRRSHMLSLYFTQQLSALYVQESQRKTQDEMLFDQESVLFEQEAILFDW
CCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
LHKTGCELLGCEAINPDSGLHQAGLTSLLAIQFCQSINHFLGCHLNVADLFAYPTLRQLT
HHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHH
LFLSQHQEDIASSSSTEAGDDRDVAIVAISCRLPGQVGVSWADYCTELSAGNSAVRHEKN
HHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHH
RLRHCVLPIGALEDIDQFDAAFFNISEREAILLDPQQRHILELSWHLFEQAGWQPEQLKQ
HHHEEEECCCCHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCHHHHCC
GDIGFYIGQSGSEYGQMLLQKNDPDYAKSYLATGICSSATSGRLAKFYGTRGPALTIDTA
CCCEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEEECC
CSSSLVALDSAMLSLQQKQCSAAVVGGVNLLLSAQIEQTLINAGMLSPKGHCATFSDDAD
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCC
GYARGEGAVLFLLKPYRQAVIDGDPVLAIIEGSVVAQDGESSSLTAPNPHAQAAMMSQLL
CCCCCCCEEEEEEEHHHHHHCCCCCEEEEEECCEEECCCCCCCCCCCCCHHHHHHHHHHH
QRASLAPDDISLLETHGTGTSLGDPVELSAIDRVYGQRKTPLRLGASKSQVGHLEAAAGG
HHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHCCH
FALARAVAQIQQQKAFGHPTLNSYNPLIAEKLSRYYFDKDTCPWVIKRVAINAFSFTGTM
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
AAAVLRKPTAVARSIKSITSIKSATSIKSVTSINVTNGAIVIHTQRLKSDPGGNLLS
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEEHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Salts [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.0408 {octanoate}} 0.0125 {octanoate}} 0.0059 {octanoate}} 0.00072 {octanoate}} 0.0013 {undecanoate}} 0.0022 {pentadecanoate}} 0.053 {CoA}} 0.035 {CoA}} 0.034 {CoA}} 0.0034 {tridecanoate}} 0.002 {laurate}} 0.0019 {laurate}} 0.0

Substrates: ATP; a long-chain carboxylic acid; CoA [C]

Specific reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate +an acyl-CoA [C]

General reaction: Acid-thiol ligation; Phosphorylation [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10557314 [H]