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The map label for this gene is iucD [H]

Identifier: 22127260

GI number: 22127260

Start: 3730087

End: 3731415

Strand: Direct

Name: iucD [H]

Synonym: y3384

Alternate gene names: 22127260

Gene position: 3730087-3731415 (Clockwise)

Preceding gene: 22127259

Following gene: 22127261

Centisome position: 81.08

GC content: 53.57

Gene sequence:

>1329_bases
ATGAATCAGCCTCTGGATTTCATCGGCATTGGCATCGGCCCATTTAACCTCAGTATTGCCGCACTTGGCAGTGAAGTTTC
TGGCTTTAACAGTAAATTTCTCGAACGTAAACCGCACTTTTCCTGGCACCCTGGCATGATGGTGCCGGACTGCCATATGC
AGACCTGCTTCCTGAAAGACTTGGTCAGCACAGTCTCCCCGACTAACACGTACAGCTTTCTTAACTATCTGGTGCAGCAT
AAGAAATTCTACCGTTTTCTGACCACCGAGCACCGGACCGTTTCCCGTGAGGAGTTTGCGGACTACCTCCGTTGGGCCGC
CAGTGGCATGAGTTCGCTCGAGTTTAGCCAAGATATTCAGAGCGTGGACTTTGACGACCAGCAGCGCCATTTTGTCGTTA
CCACCCCGCGTAATGTCTACCACGCGCGCCACGTTTGCCTGGGGATAGGCAAACGCATCAAATTGCCAGACTGCGTGACC
GAGCAAAATGACCGCTGCTTCCATGCCAGCGAAATGGCACTGCGTAATCCAGATCTGACCGGTAAACGCGTCACCATTGT
GGGCGGCGGCCAGAGCGGGGCGGACCTGTTCCTGAACATCTTTCTCGCTGCATGGGGGCAGCCAAAGCAGCTGAACTGGA
TTTCACGCCGTAACAACTACAACGCGCTGGATGAAGCCGCTTTTGCCAATGAGTACTTCATGCCGGAATACGTTGAGAGT
TTCTACACCCTGAACGACAGCGCCAAACAGCATATGCTGGCAGAACAGAGAATGACCTCTGACGGCATTACCAGTGAATC
ACTACTGGCGATTTACCGTGCTATGTACCACCAATTTGAAGTGTTACATGAAAAACCGTGGGCGCGCCTGCTCCCCAGCC
GCTCACTGACCAATATGCATACGCGCGGCAACGGTTACCAATTACTCACCCATCACCATCTCGATCAAGGCACAGAAACT
TTTGATACCGATGTGGTAATCTTCGCCACGGGTTATCAGCAGGATCGACCGGCGTTTCTCGATCCATTAGCTGATCGTCT
GCAAACCACCGCCGATTGCCAGTACCAAGTGGCTCCAGATTTTGTCCTCGACTGGCAAGGCCCGCGTGAAAACTGCTTGT
TCGCCGTGAATGCCGGTATGCATAGCCACGGCATTGCCGAACCTCAGCTCAGCCTGATGGCTTGGCGATCAGCACATATT
CTCAACCGGGCTTTAGGGCGCACTCAGTTCGATTTAACTTCCACCCCGGCGGTGATCCAATGGCGCAGCCAACAGTCGGG
TGTCCCTGCCCACCCGGAACATCCCGTGCTCAACTGCATCGACATTTAA

Upstream 100 bases:

>100_bases
AACTCACCTACTCAGAGCAGGACGGCGGCAGCCGCATGTTGCCTGATTATTTGCAGGATCTGGATAACCCCCTTTATTTG
GTCACCAAGGAGCTAGCCCA

Downstream 100 bases:

>100_bases
ATACGGCACCAAGCGTCAAAATATAACAGGCGAATTTTAACGCCATAGACCAATATTGGGAGAAAGTCACAATGAAACAC
AAACACCTCTGGGTATTAAA

Product: lysine: N6-hydroxylase

Products: NA

Alternate protein names: Lysine 6-N-hydroxylase; Lysine N(6)-hydroxylase; Lysine-N-oxygenase [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MNQPLDFIGIGIGPFNLSIAALGSEVSGFNSKFLERKPHFSWHPGMMVPDCHMQTCFLKDLVSTVSPTNTYSFLNYLVQH
KKFYRFLTTEHRTVSREEFADYLRWAASGMSSLEFSQDIQSVDFDDQQRHFVVTTPRNVYHARHVCLGIGKRIKLPDCVT
EQNDRCFHASEMALRNPDLTGKRVTIVGGGQSGADLFLNIFLAAWGQPKQLNWISRRNNYNALDEAAFANEYFMPEYVES
FYTLNDSAKQHMLAEQRMTSDGITSESLLAIYRAMYHQFEVLHEKPWARLLPSRSLTNMHTRGNGYQLLTHHHLDQGTET
FDTDVVIFATGYQQDRPAFLDPLADRLQTTADCQYQVAPDFVLDWQGPRENCLFAVNAGMHSHGIAEPQLSLMAWRSAHI
LNRALGRTQFDLTSTPAVIQWRSQQSGVPAHPEHPVLNCIDI

Sequences:

>Translated_442_residues
MNQPLDFIGIGIGPFNLSIAALGSEVSGFNSKFLERKPHFSWHPGMMVPDCHMQTCFLKDLVSTVSPTNTYSFLNYLVQH
KKFYRFLTTEHRTVSREEFADYLRWAASGMSSLEFSQDIQSVDFDDQQRHFVVTTPRNVYHARHVCLGIGKRIKLPDCVT
EQNDRCFHASEMALRNPDLTGKRVTIVGGGQSGADLFLNIFLAAWGQPKQLNWISRRNNYNALDEAAFANEYFMPEYVES
FYTLNDSAKQHMLAEQRMTSDGITSESLLAIYRAMYHQFEVLHEKPWARLLPSRSLTNMHTRGNGYQLLTHHHLDQGTET
FDTDVVIFATGYQQDRPAFLDPLADRLQTTADCQYQVAPDFVLDWQGPRENCLFAVNAGMHSHGIAEPQLSLMAWRSAHI
LNRALGRTQFDLTSTPAVIQWRSQQSGVPAHPEHPVLNCIDI
>Mature_442_residues
MNQPLDFIGIGIGPFNLSIAALGSEVSGFNSKFLERKPHFSWHPGMMVPDCHMQTCFLKDLVSTVSPTNTYSFLNYLVQH
KKFYRFLTTEHRTVSREEFADYLRWAASGMSSLEFSQDIQSVDFDDQQRHFVVTTPRNVYHARHVCLGIGKRIKLPDCVT
EQNDRCFHASEMALRNPDLTGKRVTIVGGGQSGADLFLNIFLAAWGQPKQLNWISRRNNYNALDEAAFANEYFMPEYVES
FYTLNDSAKQHMLAEQRMTSDGITSESLLAIYRAMYHQFEVLHEKPWARLLPSRSLTNMHTRGNGYQLLTHHHLDQGTET
FDTDVVIFATGYQQDRPAFLDPLADRLQTTADCQYQVAPDFVLDWQGPRENCLFAVNAGMHSHGIAEPQLSLMAWRSAHI
LNRALGRTQFDLTSTPAVIQWRSQQSGVPAHPEHPVLNCIDI

Specific function: This is one of the proteins involved in the biosynthesis of siderophores (such as the dihydroxamate siderophore, aerobactin), which are chelators that mediate the high-affinity iron transport systems induced by the organism under iron-stressed conditions

COG id: COG3486

COG function: function code Q; Lysine/ornithine N-monooxygenase

Gene ontology:

Cell location: Cytoplasm. Cell membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: =1.14.13.59 [H]

Molecular weight: Translated: 50350; Mature: 50350

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQPLDFIGIGIGPFNLSIAALGSEVSGFNSKFLERKPHFSWHPGMMVPDCHMQTCFLKD
CCCCCCEEEEEECCCCEEEEECCCHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
LVSTVSPTNTYSFLNYLVQHKKFYRFLTTEHRTVSREEFADYLRWAASGMSSLEFSQDIQ
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
SVDFDDQQRHFVVTTPRNVYHARHVCLGIGKRIKLPDCVTEQNDRCFHASEMALRNPDLT
CCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHHHCCCCCC
GKRVTIVGGGQSGADLFLNIFLAAWGQPKQLNWISRRNNYNALDEAAFANEYFMPEYVES
CCEEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHCCCCCHHHHHH
FYTLNDSAKQHMLAEQRMTSDGITSESLLAIYRAMYHQFEVLHEKPWARLLPSRSLTNMH
HHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCE
TRGNGYQLLTHHHLDQGTETFDTDVVIFATGYQQDRPAFLDPLADRLQTTADCQYQVAPD
ECCCCEEEEEEHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEECCC
FVLDWQGPRENCLFAVNAGMHSHGIAEPQLSLMAWRSAHILNRALGRTQFDLTSTPAVIQ
EEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEECCCCCCCEEE
WRSQQSGVPAHPEHPVLNCIDI
ECCCCCCCCCCCCCCCCEEECC
>Mature Secondary Structure
MNQPLDFIGIGIGPFNLSIAALGSEVSGFNSKFLERKPHFSWHPGMMVPDCHMQTCFLKD
CCCCCCEEEEEECCCCEEEEECCCHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
LVSTVSPTNTYSFLNYLVQHKKFYRFLTTEHRTVSREEFADYLRWAASGMSSLEFSQDIQ
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
SVDFDDQQRHFVVTTPRNVYHARHVCLGIGKRIKLPDCVTEQNDRCFHASEMALRNPDLT
CCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHHHCCCCCC
GKRVTIVGGGQSGADLFLNIFLAAWGQPKQLNWISRRNNYNALDEAAFANEYFMPEYVES
CCEEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHCCCCCHHHHHH
FYTLNDSAKQHMLAEQRMTSDGITSESLLAIYRAMYHQFEVLHEKPWARLLPSRSLTNMH
HHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCE
TRGNGYQLLTHHHLDQGTETFDTDVVIFATGYQQDRPAFLDPLADRLQTTADCQYQVAPD
ECCCCEEEEEEHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEECCC
FVLDWQGPRENCLFAVNAGMHSHGIAEPQLSLMAWRSAHILNRALGRTQFDLTSTPAVIQ
EEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEECCCCCCCEEE
WRSQQSGVPAHPEHPVLNCIDI
ECCCCCCCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3275632; 10064136 [H]