| Definition | Streptococcus pneumoniae ATCC 700669, complete genome. |
|---|---|
| Accession | NC_011900 |
| Length | 2,221,315 |
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The map label for this gene is dnaC [H]
Identifier: 221232904
GI number: 221232904
Start: 2183553
End: 2184905
Strand: Reverse
Name: dnaC [H]
Synonym: SPN23F_22360
Alternate gene names: 221232904
Gene position: 2184905-2183553 (Counterclockwise)
Preceding gene: 221232905
Following gene: 221232903
Centisome position: 98.36
GC content: 41.46
Gene sequence:
>1353_bases ATGGCAGAAGTAGAAGAGTTACGAGTACAACCTCAAGATATCTTAGCTGAGCAATCCGTTTTAGGGGCTATCTTTATTGA TGAGAGTAAACTTGTTTTTGTGCGAGAATACATTGAGTCTCGGGACTTTTTTAAGTATGCCCATCGTTTGATTTTCCAAG CCATGGTCGATTTATCCGATCGTGGTGATGCCATAGATGCAACAACGGTTCGTACTATCCTTGATAATCAAGGTGATTTG CAGAATATTGGTGGCTTGTCTTACTTGGTTGAGATTGTCAATTCTGTGCCAACTTCTGCTAATGCGGAGTATTATGCTAA GATTGTTGCAGAAAAAGCAATGCTACGTCGTTTAATTGCCAAGTTGACAGAGTCTGTCAACCAAGCTTACGAAGCGTCAC AACCAGCTGATGAAATTATTGCTCAGGCAGAAAAAGGGTTGATTGATGTCAGTGAAAATGCAAATCGAAGCGGGTTTAAG AACATTCGAGATGTGTTGAATCTCAACTTTGGAAATCTGGAAGCTCGCTCGCAACAAACGACCGATATTACAGGTATTGC GACAGGTTATCGTGATTTGGATCATATGACAACAGGACTTCATGAGGAGGAGTTGATTATCTTAGCAGCTCGTCCAGCAG TTGGTAAGACAGCATTTGCCTTGAATATCGCTCAGAACATTGGGACTAAGTTGGATAAAACGGTTGCTATTTTTTCACTC GAAATGGGTGCGGAAAGCTTGGTAGATCGTATGTTAGCTGCAGAAGGCTTAGTGGAGTCACATTCTATCCGTACAGGGCA ATTGACAGATGAGGAGTGGCAAAAATATACTATTGCTCAGGGTAATCTAGCTAACGCCAGTATCTATATCGATGATACGC CAGGTATTCGGATTACAGAGATTCGTTCTCGTTCTCGTAAATTGGCTCAAGAAACTGGAAATCTTGGTTTGATTTTGATA GACTATTTGCAACTTATCACGGGAACTGGTCGAGAAAATCGTCAACAAGAAGTTTCTGAAATTTCTCGTCAGTTGAAAAT ACTAGCCAAGGAATTGAAGGTTCCAGTAATCGCTCTGAGTCAGCTTTCTCGTGGTGTAGAACAACGTCAGGACAAGAGAC CGGTCTTGTCTGATATTCGTGAATCTGGGTCTATTGAGCAGGACGCTGATATCGTAGCTTTTCTCTATCGCGATGACTAC TATGAACGTGGTGGTGAAGAAGAGGAGGGTATCCCAAATAATAAGGTGGAAGTTATTATCGAGAAAAACCGTAGTGGAGC TCGTGGAACAGTGGAATTGATTTTCCAAAAAGAATACAATAAATTTTCAAGTATCTCAAAGAGGGAGGCATAA
Upstream 100 bases:
>100_bases GTGAAAATCTATCAAGATATCACAAGTGTAATCAATCTTCGTGTGAAAGAAGGATAAGTTTACACCTTCTTGACAAGATT GTAAAAGGAAGGGAAGTCTG
Downstream 100 bases:
>100_bases GATGTCAGATGCATTTACAGATGTAGCCAAGATGAAAAAAATCAAAGAAGAAATCAAGGCACATGAGGGACAAGTCGTAG AAATGACTTTGGAGAATGGT
Product: replicative DNA helicase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 450; Mature: 449
Protein sequence:
>450_residues MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFFKYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDL QNIGGLSYLVEIVNSVPTSANAEYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTAFALNIAQNIGTKLDKTVAIFSL EMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKYTIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILI DYLQLITGTGRENRQQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDY YERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
Sequences:
>Translated_450_residues MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFFKYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDL QNIGGLSYLVEIVNSVPTSANAEYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTAFALNIAQNIGTKLDKTVAIFSL EMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKYTIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILI DYLQLITGTGRENRQQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDY YERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA >Mature_449_residues AEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFFKYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQ NIGGLSYLVEIVNSVPTSANAEYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFKN IRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTAFALNIAQNIGTKLDKTVAIFSLE MGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKYTIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILID YLQLITGTGRENRQQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYY ERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.
COG id: COG0305
COG function: function code L; Replicative DNA helicase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 SF4 helicase domain [H]
Homologues:
Organism=Escherichia coli, GI1790486, Length=447, Percent_Identity=44.7427293064877, Blast_Score=357, Evalue=1e-100,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR007692 - InterPro: IPR007694 - InterPro: IPR007693 - InterPro: IPR016136 [H]
Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]
EC number: =3.6.4.12 [H]
Molecular weight: Translated: 50204; Mature: 50073
Theoretical pI: Translated: 4.60; Mature: 4.60
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 1.3 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 1.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFFKYAHRLIFQAMVDLSD CCCHHHHHCCHHHHHHHHHHHEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC RGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANAEYYAKIVAEKAMLRRLIA CCCCCHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH KLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFKNIRDVLNLNFGNLEARSQQT HHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCC TDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTAFALNIAQNIGTKLDKTVAIFSL CCHHHHHHCHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHEEEEEEE EMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKYTIAQGNLANASIYIDDTPGIRITE CCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHEEEEECCCCCCEEEEEECCCCEEEHH IRSRSRKLAQETGNLGLILIDYLQLITGTGRENRQQEVSEISRQLKILAKELKVPVIALS HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHH QLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYYERGGEEEEGIPNNKVEVII HHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEEEHHHHHHCCCCCCCCCCCCCEEEEE EKNRSGARGTVELIFQKEYNKFSSISKREA ECCCCCCCCCEEEEEHHHHHHHHHHHHCCC >Mature Secondary Structure AEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFFKYAHRLIFQAMVDLSD CCHHHHHCCHHHHHHHHHHHEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC RGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANAEYYAKIVAEKAMLRRLIA CCCCCHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH KLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFKNIRDVLNLNFGNLEARSQQT HHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCC TDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTAFALNIAQNIGTKLDKTVAIFSL CCHHHHHHCHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHEEEEEEE EMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKYTIAQGNLANASIYIDDTPGIRITE CCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHEEEEECCCCCCEEEEEECCCCEEEHH IRSRSRKLAQETGNLGLILIDYLQLITGTGRENRQQEVSEISRQLKILAKELKVPVIALS HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHH QLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYYERGGEEEEGIPNNKVEVII HHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEEEHHHHHHCCCCCCCCCCCCCEEEEE EKNRSGARGTVELIFQKEYNKFSSISKREA ECCCCCCCCCEEEEEHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7584024; 9384377; 1312531 [H]