Click here to switch to the map view.

The map label for this gene is yiaY [H]

Identifier: 221232862

GI number: 221232862

Start: 2132860

End: 2134011

Strand: Reverse

Name: yiaY [H]

Synonym: SPN23F_21890

Alternate gene names: 221232862

Gene position: 2134011-2132860 (Counterclockwise)

Preceding gene: 221232863

Following gene: 221232861

Centisome position: 96.07

GC content: 41.41

Gene sequence:

>1152_bases
ATGGCTACATTTTATGTTCCGGCAGTCAACCTTATTGGTAAAGGTGTTGTAAATGAAGTGGGTCCTTATATCAAGGAACT
TGGCTATAAAAAGGCACTTTTGGTGACAGATAAGTACATCGAAGGCAGTGATATTTTACCTAAGACTTTAAAACCACTGG
ATACAGAAGGAATCGAATATGTCATCTTTAGCGATGTAGAGCCAAACCCTACTTGTAAAAATGTCACAGATGGGGTAGCT
GCTTTGCAAGAACATGGCTGTGACTTTATCATCAGTCTTGGCGGGGGTTCTCCACAGGATGCAGCTAGTTGTATTTCTAT
CATGGCTACAAATGGTGGAAGACCACAGGATTATGAAGGGCTTCATAAGTCTGCTAAAAAAGGCTTGCCAGTTGTGGCGA
TCAATACAACGGCAGGTACATCAGCAGAAATTACCATTAACTATGTGATTACTGATGAAGAACGCAAGGTTAAGATGGTA
ATGGTTGACAAGAATAGCCTTGCTCTTATCTCTGTTAATGACCCGGAACTCATGCTTTCCAAACCTAAAGGCCTGACTGC
TGCTACTGGTATGGATGCTCTGACTCACGCTGTTGAAGCTTTGGTAACACCTGGTGCTTATGATGTAACCAAGAAACTGT
CTATTGGTGCTATTGAGCTTATCAAGGAATATCTTCCTCGTGCTGTAGAAAATGGACATGATATTGAAGCGCGTGAAGGT
ATGGTCAATGCCATCTTCCTTGGTGGTATGAGCTTTAATAATGCTGGTCTTGGCTATGTTCACTCAATGGCTCACCAACT
CGGTGCAGTATATAATTTGCCACATGGTGTTTGCTGTGCCATGTTGCTACCAGTTATAGAACGTGAAAATGCTAAACGTG
TACCAGAAGCTTTCCGCAATGTTGCCAAAGCCTTGGGACTTCATGTAGAAGGTAAATCAGATCAAGAATGTGCCGATTAT
GCGATTGCTGAGATTGAGAAGCTTTCTGAGACAGTAGGTATTCCTAAGAAACTGACTGAACTTGGTATTGAAGAAAAAGA
TTTCGACTTTGAATACCTTTCTAAGAATGCCTTGATTGATGCCTGCGCACCAGGAAATCCATTTATGCCAACCTTAGAAG
AAACGATTGCCTTTTATAAAGAGTTATTTTAG

Upstream 100 bases:

>100_bases
AAAAATATTTGTTAAACAATTCACAAATAATTGAAAACGAATACAAAAAGTAATATAATGATGTTAAATAGATAGCGCAA
AGGCGCAGGAGGAAAATTAT

Downstream 100 bases:

>100_bases
CAAGAGATTGGACGACAATAGGACAATTCACCTCTAATTATTGACATTTCAGGAAAAATCGCAGTAAAAACGGCACAGCC
TTCTTTAAATGTGCTATAAT

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSDILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVA
ALQEHGCDFIISLGGGSPQDAASCISIMATNGGRPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAIELIKEYLPRAVENGHDIEAREG
MVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHGVCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADY
AIAEIEKLSETVGIPKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF

Sequences:

>Translated_383_residues
MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSDILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVA
ALQEHGCDFIISLGGGSPQDAASCISIMATNGGRPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAIELIKEYLPRAVENGHDIEAREG
MVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHGVCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADY
AIAEIEKLSETVGIPKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF
>Mature_382_residues
ATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSDILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAA
LQEHGCDFIISLGGGSPQDAASCISIMATNGGRPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMVM
VDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAIELIKEYLPRAVENGHDIEAREGM
VNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHGVCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYA
IAEIEKLSETVGIPKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=375, Percent_Identity=24.8, Blast_Score=98, Evalue=2e-20,
Organism=Escherichia coli, GI48994951, Length=379, Percent_Identity=47.7572559366755, Blast_Score=356, Evalue=1e-99,
Organism=Escherichia coli, GI1789163, Length=375, Percent_Identity=41.3333333333333, Blast_Score=286, Evalue=1e-78,
Organism=Escherichia coli, GI87082107, Length=377, Percent_Identity=35.8090185676393, Blast_Score=214, Evalue=9e-57,
Organism=Escherichia coli, GI1787493, Length=379, Percent_Identity=32.7176781002639, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1789386, Length=353, Percent_Identity=23.5127478753541, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17537053, Length=381, Percent_Identity=26.246719160105, Blast_Score=115, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6321181, Length=380, Percent_Identity=42.1052631578947, Blast_Score=308, Evalue=1e-84,
Organism=Drosophila melanogaster, GI24657991, Length=375, Percent_Identity=24.8, Blast_Score=88, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 41241; Mature: 41110

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSDILPKTLKPLDTEGIEY
CCEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHCCCCCCCCEEE
VIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAASCISIMATNGGRPQDYEG
EEEECCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCHHH
LHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMVMVDKNSLALISVNDPELMLS
HHHHHHCCCCEEEEECCCCCCEEEEEEEEEECCCCEEEEEEEECCCEEEEEECCCCEEEE
KPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAIELIKEYLPRAVENGHDIEAREG
CCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHCC
MVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHGVCCAMLLPVIERENAKRVPEAFRN
CEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
VAKALGLHVEGKSDQECADYAIAEIEKLSETVGIPKKLTELGIEEKDFDFEYLSKNALID
HHHHHCEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHCCCCEEE
ACAPGNPFMPTLEETIAFYKELF
ECCCCCCCCCHHHHHHHHHHHHC
>Mature Secondary Structure 
ATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSDILPKTLKPLDTEGIEY
CEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHCCCCCCCCEEE
VIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAASCISIMATNGGRPQDYEG
EEEECCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCHHH
LHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMVMVDKNSLALISVNDPELMLS
HHHHHHCCCCEEEEECCCCCCEEEEEEEEEECCCCEEEEEEEECCCEEEEEECCCCEEEE
KPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAIELIKEYLPRAVENGHDIEAREG
CCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHCC
MVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHGVCCAMLLPVIERENAKRVPEAFRN
CEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
VAKALGLHVEGKSDQECADYAIAEIEKLSETVGIPKKLTELGIEEKDFDFEYLSKNALID
HHHHHCEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHCCCCEEE
ACAPGNPFMPTLEETIAFYKELF
ECCCCCCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]