Definition Streptococcus pneumoniae ATCC 700669, complete genome.
Accession NC_011900
Length 2,221,315

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The map label for this gene is argR

Identifier: 221232789

GI number: 221232789

Start: 2045038

End: 2045484

Strand: Reverse

Name: argR

Synonym: SPN23F_21020

Alternate gene names: 221232789

Gene position: 2045484-2045038 (Counterclockwise)

Preceding gene: 221232799

Following gene: 221232788

Centisome position: 92.08

GC content: 37.36

Gene sequence:

>447_bases
ATGAGAAAAAGAGATCGTCATCAGTTAATAAAAAAAATGATTACTGAGGAGAAATTAAGTACACAAAAAGAAATTCAAGA
TCGGTTGGAGGCGCACAATGTTTGTGTGACGCAGACAACCTTGTCTCGTGATTTGCGCGAAATCGGCTTGACCAAGGTCA
AGAAAAATGATATGGTGTATTATGTACTAGTAAATGAGACAGAAAAGATTGATTTGGTGGAATTTTTGTCTCATCATTTA
GAAGGTGTTGCAAGAGCAGAGTTTACCTTGGTGCTTCATACCAAATTGGGAGAAGCCTCTGTTTTGGCAAATATTGTAGA
TGTAAACAAGGATGAATGGATTTTAGGAACAGTTGCTGGTGCCAATACCTTATTGGTTATTTGTCGAGATCAGCACGTTG
CCAAACTCATGGAAGATCGTTTGCTAGATTTGATGAAAGATAAGTAA

Upstream 100 bases:

>100_bases
CACAATTTTAAAGAAAGAAGAAAAAATTTTTGAAATCTCCTGTTTTTTTGGTATAATATGGTTATAAATATAGTTATAAA
TATGCACGCAAGAGGATTTT

Downstream 100 bases:

>100_bases
GGTCTTGGGAGTTGCTCTCAAGACTTATTTTTGAAAAGGAGAGACAGAAAATGGCGATAGAAAAGCTATCACCCGGCATG
CAACAGTATGTGGATATTAA

Product: arginine repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRDLREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHL
EGVARAEFTLVLHTKLGEASVLANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK

Sequences:

>Translated_148_residues
MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRDLREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHL
EGVARAEFTLVLHTKLGEASVLANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK
>Mature_148_residues
MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRDLREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHL
EGVARAEFTLVLHTKLGEASVLANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK

Specific function: Regulates arginine biosynthesis genes

COG id: COG1438

COG function: function code K; Arginine repressor

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgR family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGR_STRPN (P0A2Y2)

Other databases:

- EMBL:   M18729
- EMBL:   AE005672
- PIR:   A95243
- PIR:   B28667
- RefSeq:   NP_346498.1
- ProteinModelPortal:   P0A2Y2
- SMR:   P0A2Y2
- EnsemblBacteria:   EBSTRT00000025753
- GeneID:   930261
- GenomeReviews:   AE005672_GR
- KEGG:   spn:SP_2077
- TIGR:   SP_2077
- GeneTree:   EBGT00050000027499
- HOGENOM:   HBG697909
- OMA:   IYVTQTT
- ProtClustDB:   CLSK884193
- BioCyc:   SPNE170187-1:SP_2077-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00173
- InterPro:   IPR001669
- InterPro:   IPR020899
- InterPro:   IPR020900
- InterPro:   IPR011991
- Gene3D:   G3DSA:3.30.1360.40
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR01467
- ProDom:   PD007402
- TIGRFAMs:   TIGR01529

Pfam domain/function: PF01316 Arg_repressor; PF02863 Arg_repressor_C; SSF55252 Arg_repress

EC number: NA

Molecular weight: Translated: 17063; Mature: 17063

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRDLREIGLTKVKKNDMVY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHCCCEEECCCEEE
YVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVLANIVDVNKDEWILGTVAG
EEEECCCCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECC
ANTLLVICRDQHVAKLMEDRLLDLMKDK
CCEEEEEECCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRDLREIGLTKVKKNDMVY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHCCCEEECCCEEE
YVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVLANIVDVNKDEWILGTVAG
EEEECCCCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECC
ANTLLVICRDQHVAKLMEDRLLDLMKDK
CCEEEEEECCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3275608; 11463916