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The map label for this gene is yabD [H]

Identifier: 221232716

GI number: 221232716

Start: 1952453

End: 1953226

Strand: Reverse

Name: yabD [H]

Synonym: SPN23F_20120

Alternate gene names: 221232716

Gene position: 1953226-1952453 (Counterclockwise)

Preceding gene: 221232717

Following gene: 221232715

Centisome position: 87.93

GC content: 45.22

Gene sequence:

>774_bases
ATGATTTTTGATACACATACACACTTGAATGTAGAAGAATTTGCAGGTCGTGAGGCAGAAGAAATTGCCTTGGCTGCTGA
GATGGGTGTGATACAGATGAATATTGTTGGTTTTGATAAACCGACGATTGAGCGTGCCTTGGAGTTGGTAGATGAGTATG
AGCAGCTCTATGCGACTATTGGTTGGCATCCTACAGAAGCTGGTACTTATACAGAGGAAGTTGAGGCTTACTTGTTGGAT
AAGTTAAAACATCCCAAGGTTGTGGCTCTAGGTGAAATTGGCTTAGACTACCATTGGATGACAGCGCCCAAAGAGGTGCA
GGAGCAGGTTTTTCGTCGTCAGATTCAGCTATCTAAGGACTTGGATTTGCCTTTTGTTGTCCATACCCGTGATGCGCTGG
AAGATACCTATGAGATTATCAAGAGTGAGGGCGTTGGTCCTCGTGGTGGTATCATGCATTCATTTTCAGGGACGCTTGAG
TGGGCAGAGAAGTTTGTGGATCTTGGTATGACCATTTCCTTCTCAGGAGTGGTGACTTTCAAGAAGGCAACTGACCTCCA
AGAAGCAGCTAAAGAGTTACCTTTGGACAAGATTTTGGTGGAAACAGATGCGCCTTACTTAGCACCTGTACCCAAGCGTG
GTCGTGAAAATAAAACAGCCTATACTCGCTATGTGGTCGACTTTATCGCTGACTTGCGTGGTATGACGACAGAAGAGCTG
GCGGTAGAAACGACTGCAAATGCAGAACGAATTTTTGGATTGGACAGCAAGTAA

Upstream 100 bases:

>100_bases
GCAGAATAGCTCTCTATTGAAGAGAGGAGGGGAAACCGAAAAATTAGGTGCTCCTCCTCTTTTTTGGTATAATAGAAGAT
AGAAAACGAGGTTAGAAGAG

Downstream 100 bases:

>100_bases
TGAAAGAGAAAATTTCTCAAGTTATCGTGGTTGAAGGTCGCGATGATACGGTCAATCTCAAGCGTTATTTCGATGTGGAG
ACCTATGAGACACGAGGTTC

Product: TatD related DNase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MIFDTHTHLNVEEFAGREAEEIALAAEMGVIQMNIVGFDKPTIERALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLD
KLKHPKVVALGEIGLDYHWMTAPKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKILVETDAPYLAPVPKRGRENKTAYTRYVVDFIADLRGMTTEEL
AVETTANAERIFGLDSK

Sequences:

>Translated_257_residues
MIFDTHTHLNVEEFAGREAEEIALAAEMGVIQMNIVGFDKPTIERALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLD
KLKHPKVVALGEIGLDYHWMTAPKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKILVETDAPYLAPVPKRGRENKTAYTRYVVDFIADLRGMTTEEL
AVETTANAERIFGLDSK
>Mature_257_residues
MIFDTHTHLNVEEFAGREAEEIALAAEMGVIQMNIVGFDKPTIERALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLD
KLKHPKVVALGEIGLDYHWMTAPKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKILVETDAPYLAPVPKRGRENKTAYTRYVVDFIADLRGMTTEEL
AVETTANAERIFGLDSK

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI225903424, Length=226, Percent_Identity=38.0530973451327, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI14042943, Length=194, Percent_Identity=33.5051546391753, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI225903439, Length=181, Percent_Identity=33.1491712707182, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI110349730, Length=266, Percent_Identity=27.8195488721804, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI110349734, Length=266, Percent_Identity=27.8195488721804, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI226061853, Length=271, Percent_Identity=27.6752767527675, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI226061614, Length=257, Percent_Identity=27.2373540856031, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI226061595, Length=228, Percent_Identity=28.0701754385965, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI1787342, Length=264, Percent_Identity=39.0151515151515, Blast_Score=179, Evalue=1e-46,
Organism=Escherichia coli, GI48994985, Length=258, Percent_Identity=31.3953488372093, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI87082439, Length=255, Percent_Identity=31.7647058823529, Blast_Score=134, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17559024, Length=258, Percent_Identity=27.5193798449612, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI71980746, Length=264, Percent_Identity=27.2727272727273, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17543026, Length=218, Percent_Identity=27.9816513761468, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17565396, Length=179, Percent_Identity=30.7262569832402, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24586117, Length=181, Percent_Identity=35.9116022099448, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI221330018, Length=181, Percent_Identity=35.9116022099448, Blast_Score=103, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24648690, Length=287, Percent_Identity=29.2682926829268, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28956; Mature: 28956

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFDTHTHLNVEEFAGREAEEIALAAEMGVIQMNIVGFDKPTIERALELVDEYEQLYATI
CEECCCCCCCHHHHCCCCHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
GWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTAPKEVQEQVFRRQIQLSKD
CCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHCC
LDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLEWAEKFVDLGMTISFSGVVTF
CCCCEEEECHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHCCCEEEECCEEEE
KKATDLQEAAKELPLDKILVETDAPYLAPVPKRGRENKTAYTRYVVDFIADLRGMTTEEL
HHHCCHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHH
AVETTANAERIFGLDSK
EEECCCCHHHEECCCCC
>Mature Secondary Structure
MIFDTHTHLNVEEFAGREAEEIALAAEMGVIQMNIVGFDKPTIERALELVDEYEQLYATI
CEECCCCCCCHHHHCCCCHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
GWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTAPKEVQEQVFRRQIQLSKD
CCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHCC
LDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLEWAEKFVDLGMTISFSGVVTF
CCCCEEEECHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHCCCEEEECCEEEE
KKATDLQEAAKELPLDKILVETDAPYLAPVPKRGRENKTAYTRYVVDFIADLRGMTTEEL
HHHCCHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHH
AVETTANAERIFGLDSK
EEECCCCHHHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]