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The map label for this gene is secA

Identifier: 221232436

GI number: 221232436

Start: 1644728

End: 1647241

Strand: Reverse

Name: secA

Synonym: SPN23F_17010

Alternate gene names: 221232436

Gene position: 1647241-1644728 (Counterclockwise)

Preceding gene: 221232437

Following gene: 221232435

Centisome position: 74.16

GC content: 43.24

Gene sequence:

>2514_bases
ATGGCTAATATTTTAAAAACAATTATCGAAAATGATAAAGGAGAAATCCGTCGTCTGGAAAAGATGGCTGACAAGGTTTT
CAAATACGAAGACCAAATGGCTGCTTTGACTGACGACCAACTAAAAGCAAAAACAGTTGAATTTAAGGAACGTTATCAAA
ATGGAGAATCACTGGATTCATTGCTTTACGAAGCATTTGCGGTTGTCCGTGAAGGTGCCAAACGTGTCCTAGGTCTCTTC
CCTTATAAGGTTCAGGTCATGGGGGGGATTGTTCTTCACCATGGTGACGTGCCAGAGATGCGTACAGGGGAAGGGAAAAC
CTTAACTGCGACCATGCCGGTATACCTCAATGCCCTTTCAGGTAAAGGGGTTCACGTAGTTACGGTTAATGAATACCTGT
CAGAACGTGACGCGACTGAGATGGGTGAATTGTACTCTTGGCTTGGTTTGTCAGTAGGGATTAACTTGGCTACCAAATCT
CCAATGGAGAAAAAAGAAGCCTATGAGTGTGATATTACTTACTCAACTAACTCAGAAATCGGATTTGACTACCTTCGTGA
CAACATGGTCGTTCGCGCTGAAAACATGGTACAACGTCCGCTTAACTATGCCTTGGTCGATGAGGTTGACTCTATCTTGA
TTGACGAGGCTCGTACACCTTTGATTGTATCAGGTGCCAATGCGGTTGAAACCAGTCAGTTGTATCACATGGCAGACCAC
TATGTAAAATCTTTGAACAAAGATGACTACATCATCGATGTGCAGTCTAAGACTATTGGTTTGTCTGATTCAGGGATTGA
CAGGGCTGAAAGCTACTTCAAACTTGAAAACCTCTATGACATCGAAAACGTGGCTTTGACCCACTTTATCGATAACGCCC
TTCGTGCCAACTACATCATGCTTCTCGATATTGACTATGTGGTGAGCGAAGAGCAAGAAATCTTGATTGTCGACCAATTT
ACAGGTCGTACCATGGAAGGTCGTCGTTATTCTGATGGATTGCACCAAGCTATTGAAGCCAAAGAAGGTGTGCCAATCCA
GGATGAAACCAAGACATCTGCCTCAATCACGTACCAAAACCTTTTCCGTATGTACAAAAAATTGTCTGGTATGACGGGTA
CAGGTAAGACTGAGGAAGAAGAATTTCGTGAAATCTACAACATTCGTGTTATTCCAATCCCAACAAACCGTCCTGTTCAA
CGTATTGACCACTCAGACCTTCTTTATGCAAGTATCGAATCTAAGTTTAAAGCGGTTGTCGAAGACGTTAAGGCTCGTTA
CCAAAAGGGTCAACCTGTCTTGGTTGGTACAGTAGCGGTTGAAACTAGTGACTACATTTCTAAGAAATTGGTTGCAGCTG
GTGTTCCTCACGAAGTCTTGAATGCCAAAAACCACTATAGAGAAGCCCAAATCATCATGAATGCTGGTCAACGTGGTGCC
GTTACCATCGCAACCAACATGGCGGGTCGTGGTACCGACATCAAGCTTGGTGAAGGTGTTCGTGAACTTGGAGGACTTTG
TGTTATTGGTACAGAACGTCATGAAAGTCGTCGTATCGATAACCAGCTTCGTGGACGTTCAGGTCGTCAAGGAGATCCAG
GTGAGTCACAATTCTACCTATCTCTTGAAGATGATTTGATGAAACGTTTTGGTTCTGAACGCTTGAAGGGAATCTTTGAA
CGTCTCAACATGTCTGAAGAGGCCATTGAGTCTCGCATGTTGACGCGTCAGGTTGAAGCAGCTCAGAAACGTGTCGAAGG
AAATAACTACGATACCCGTAAACAAGTCCTTCAATACGATGATGTCATGCGTGAACAACGTGAGATTATCTATGCTCAAC
GTTACGATGTCATCACTGCAGATCGTGACTTGGCACCTGAAATTCAGTCTATGATCAAACGCACGATTGAACGTGTCGTT
GATGGTCATGCGCGTGCCAAACAAGATGAAAAACTAGAGGCAATTTTGAACTTTGCTAAGTACAACTTGCTTCCTGAAGA
TTCTATTACGATGGAAGACTTGTCAGGCTTGTCTGATAAGGCCATCAAGGAAGAGCTTTTCCAACGTTCCTTGAAGGTTT
ACGATAGTCAGGTTTCAAAACTACGCGATGAAGAAGCAGTTAAAGAATTCCAAAAAGTTTTGATTCTACGAGTGGTGGAT
AACAAGTGGACAGATCATATCGATGCCCTTGATCAATTGCGTAACGCGGTTGGACTTCGTGGCTATGCTCAGAACAACCC
TGTTGTTGAGTATCAGGCAGAAGGTTTCCGTATGTTTAATGATATGATTGGTTCGATTGAGTTTGATGTGACACGCTTGA
TGATGAAAGCACAAATTCATGAACAAGAAAGACCACAGGCAGAACGTCATATCAGTACAACAGCGACTCGCAATATCGCT
GCTCACCAAGCAAGTATGCCAGAAGATTTGGATTTGAGCCAGATTGGACGCAATGAACTTTGCCCATGTGGTTCTGGTAA
GAAATTTAAAAACTGTCACGGTAAAAGACAATAA

Upstream 100 bases:

>100_bases
TTCCTTTTCAAAATGGGGATTCTTCCTTGAAAATAATCAGTAATTGTGCTAAAATTAAAGGAACATTCTAAAATATTCGG
AATTTAAAGTAAGGAAAAAC

Downstream 100 bases:

>100_bases
AATGAGATAGTTTAGAGGCGGATATCTTGTGAAAAGTAAATTTTTACTGGGTATCCGTTTGCTTTATAAGGAGATGAGTT
ATGGTATTTACAGCAAAAAG

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 837; Mature: 836

Protein sequence:

>837_residues
MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAKTVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLF
PYKVQVMGGIVLHHGDVPEMRTGEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEARTPLIVSGANAVETSQLYHMADH
YVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLENLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQF
TGRTMEGRRYSDGLHQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIPIPTNRPVQ
RIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKLVAAGVPHEVLNAKNHYREAQIIMNAGQRGA
VTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFE
RLNMSEEAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDLAPEIQSMIKRTIERVV
DGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAIKEELFQRSLKVYDSQVSKLRDEEAVKEFQKVLILRVVD
NKWTDHIDALDQLRNAVGLRGYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRNIA
AHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ

Sequences:

>Translated_837_residues
MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAKTVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLF
PYKVQVMGGIVLHHGDVPEMRTGEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEARTPLIVSGANAVETSQLYHMADH
YVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLENLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQF
TGRTMEGRRYSDGLHQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIPIPTNRPVQ
RIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKLVAAGVPHEVLNAKNHYREAQIIMNAGQRGA
VTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFE
RLNMSEEAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDLAPEIQSMIKRTIERVV
DGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAIKEELFQRSLKVYDSQVSKLRDEEAVKEFQKVLILRVVD
NKWTDHIDALDQLRNAVGLRGYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRNIA
AHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ
>Mature_836_residues
ANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAKTVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFP
YKVQVMGGIVLHHGDVPEMRTGEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKSP
MEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEARTPLIVSGANAVETSQLYHMADHY
VKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLENLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFT
GRTMEGRRYSDGLHQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIPIPTNRPVQR
IDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKLVAAGVPHEVLNAKNHYREAQIIMNAGQRGAV
TIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFER
LNMSEEAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDLAPEIQSMIKRTIERVVD
GHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAIKEELFQRSLKVYDSQVSKLRDEEAVKEFQKVLILRVVDN
KWTDHIDALDQLRNAVGLRGYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRNIAA
HQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=893, Percent_Identity=44.568868980963, Blast_Score=732, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA1_STRPN (Q97PD6)

Other databases:

- EMBL:   AE005672
- PIR:   C95198
- RefSeq:   NP_346140.1
- HSSP:   P43803
- ProteinModelPortal:   Q97PD6
- SMR:   Q97PD6
- EnsemblBacteria:   EBSTRT00000026672
- GeneID:   931130
- GenomeReviews:   AE005672_GR
- KEGG:   spn:SP_1702
- TIGR:   SP_1702
- GeneTree:   EBGT00050000027662
- HOGENOM:   HBG284200
- OMA:   GGMVLHD
- ProtClustDB:   PRK12904
- BioCyc:   SPNE170187-1:SP_1702-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR004027
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116
- Gene3D:   G3DSA:1.10.3060.10
- PRINTS:   PR00906
- SMART:   SM00957
- SMART:   SM00958
- TIGRFAMs:   TIGR00963

Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW; SSF81767 SecA_PP_bd; SSF81886 SecA_SW

EC number: NA

Molecular weight: Translated: 95047; Mature: 94916

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAKTVEFKERYQNGESLDS
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHH
LLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRTGEGKTLTATMPVYLNALS
HHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEECCCCCCCCCCCCCEEEEECCCHHECCC
GKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKSPMEKKEAYECDITYSTNSEI
CCCEEEEEHHHHHHHCCHHHHHHHHHHHHHHHCEEECCCCCCHHHCCEEEEEEECCCCCC
GFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEARTPLIVSGANAVETSQLYHMADH
CHHHHHCCEEEEHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHH
YVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLENLYDIENVALTHFIDNALRANYIM
HHHHCCCCCEEEEECCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
LLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGLHQAIEAKEGVPIQDETKTSASITYQN
EEEEHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
LFRMYKKLSGMTGTGKTEEEEFREIYNIRVIPIPTNRPVQRIDHSDLLYASIESKFKAVV
HHHHHHHHCCCCCCCCCCHHHHHHHHCCEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHH
EDVKARYQKGQPVLVGTVAVETSDYISKKLVAAGVPHEVLNAKNHYREAQIIMNAGQRGA
HHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCCCCCE
VTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYL
EEEEECCCCCCCCCCCCCCHHHHCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEE
SLEDDLMKRFGSERLKGIFERLNMSEEAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYD
EEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
DVMREQREIIYAQRYDVITADRDLAPEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAK
HHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHH
YNLLPEDSITMEDLSGLSDKAIKEELFQRSLKVYDSQVSKLRDEEAVKEFQKVLILRVVD
HCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NKWTDHIDALDQLRNAVGLRGYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIH
CCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EQERPQAERHISTTATRNIAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ
HHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCHHCCCCCCC
>Mature Secondary Structure 
ANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAKTVEFKERYQNGESLDS
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHH
LLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRTGEGKTLTATMPVYLNALS
HHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEECCCCCCCCCCCCCEEEEECCCHHECCC
GKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKSPMEKKEAYECDITYSTNSEI
CCCEEEEEHHHHHHHCCHHHHHHHHHHHHHHHCEEECCCCCCHHHCCEEEEEEECCCCCC
GFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEARTPLIVSGANAVETSQLYHMADH
CHHHHHCCEEEEHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHH
YVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLENLYDIENVALTHFIDNALRANYIM
HHHHCCCCCEEEEECCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
LLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGLHQAIEAKEGVPIQDETKTSASITYQN
EEEEHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
LFRMYKKLSGMTGTGKTEEEEFREIYNIRVIPIPTNRPVQRIDHSDLLYASIESKFKAVV
HHHHHHHHCCCCCCCCCCHHHHHHHHCCEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHH
EDVKARYQKGQPVLVGTVAVETSDYISKKLVAAGVPHEVLNAKNHYREAQIIMNAGQRGA
HHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCCCCCE
VTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYL
EEEEECCCCCCCCCCCCCCHHHHCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEE
SLEDDLMKRFGSERLKGIFERLNMSEEAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYD
EEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
DVMREQREIIYAQRYDVITADRDLAPEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAK
HHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHH
YNLLPEDSITMEDLSGLSDKAIKEELFQRSLKVYDSQVSKLRDEEAVKEFQKVLILRVVD
HCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NKWTDHIDALDQLRNAVGLRGYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIH
CCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EQERPQAERHISTTATRNIAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ
HHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11463916