Click here to switch to the map view.

The map label for this gene is ftsA [H]

Identifier: 221232404

GI number: 221232404

Start: 1606161

End: 1607534

Strand: Reverse

Name: ftsA [H]

Synonym: SPN23F_16680

Alternate gene names: 221232404

Gene position: 1607534-1606161 (Counterclockwise)

Preceding gene: 221232405

Following gene: 221232403

Centisome position: 72.37

GC content: 43.09

Gene sequence:

>1374_bases
ATGGCTAGAGAAGGCTTTTTTACAGGTCTAGATATTGGAACAAGCTCTGTCAAGGTGCTTGTGGCCGAGCAGAGAAATGG
TGAATTAAATGTAATTGGCGTGAGTAATGCCAAAAGTAAAGGTGTAAAGGATGGAATTATTGTTGATATTGATGCAGCAG
CAACTGCTATCAAGTCAGCCATTTCCCAAGCGGAAGAAAAGGCAGGCATTTCGATTAAATCAGTGAATGTCGGCTTGCCT
GGTAATCTTTTGCAGGTAGAACCAACTCAGGGGATGATTCCAGTAACATCTGATACTAAGGAAATTACGGATCAAGATGT
TGAAAATGTTGTCAAATCAGCTTTGACAAAGAGTATGACACCTGACCGTGAAGTCATTACCTTTATTCCTGAAGAATTTA
TTGTGGATGGTTTCCAAGGGATTCGTGACCCACGTGGCATGATGGGGGTTCGCCTTGAAATGCGTGGTTTGCTTTATACA
GGACCTCGTACTATCTTGCACAATTTGCGTAAGACGGTTGAGCGTGCAGGTGTTCAGGTTGAAAATGTTATCATTTCACC
ACTAGCAATGGTTCAGTCTGTTTTGAACGAAGGGGAACGTGAATTTGGTGCTACAGTGATTGATATGGGGGCAGGTCAAA
CGACTGTCGCTACAATCCGTAATCAAGAACTCCAGTTCACACATATTCTCCAAGAAGGTGGAGATTATGTAACTAAAGAT
ATCTCCAAGGTTTTGAAAACCTCTCGCAAATTAGCGGAAGGCTTAAAACTGAATTACGGGGAAGCCTATCCGCCTCTTGC
AAGCAAAGAAACCTTCCAAGTAGAGGTTATTGGAGAAGTAGAAGCAGTCGAAGTGACGGAAGCCTACTTGTCAGAAATTA
TTTCTGCACGAATCAAGCACATCCTTGAACAAATCAAGCAAGAATTAGATAGAAGGCGTCTATTGGACCTCCCTGGTGGT
ATTGTCTTAATCGGTGGGAATGCCATTTTACCAGGTATGGTTGAGCTTGCTCAGGAAGTCTTTGGCGTCCGTGTCAAGCT
TTATGTTCCAAATCAAGTTGGTATCCGTAATCCAGCCTTTGCGCATGTGATTAGTTTATCAGAATTTGCGGGTCAATTAA
CAGAAGTTAATCTTTTGGCTCAGGGAGCGATAAAAGGTGAGAATGACTTAAGTCATCAGCCAATTAGTTTTGGTGGGATG
CTGCAAAAAACAGCTCAGTTTGTACAATCAACGCCTGTTCAACCAGCTCCTGCTCCAGAAGTAGAGCCGGTGGCGCCTAC
AGAACCAATGGCGGATTTCCAACAAGCTTCACAAAATAAACCGAAATTAGCAGATCGTTTCCGTGGCTTGATCGGAAGCA
TGTTTGACGAATAA

Upstream 100 bases:

>100_bases
AAATTTTTTGTGTTATAATATTTTGTGAATAGCTATGCCTATGTTTAGCTATGGAATAATACGAAGTGCGAAACTTGGAA
GATAGAGAGGAAGCGATGTA

Downstream 100 bases:

>100_bases
AGAGGAAAAATAAATTATGACATTTTCATTTGATACAGCTGCTGCTCAAGGGGCAGTGATTAAAGTAATTGGTGTCGGTG
GAGGTGGTGGCAATGCCATC

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKDGIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLP
GNLLQVEPTQGMIPVTSDTKEITDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVATIRNQELQFTHILQEGGDYVTKD
ISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEVIGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGG
IVLIGGNAILPGMVELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSHQPISFGGM
LQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGLIGSMFDE

Sequences:

>Translated_457_residues
MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKDGIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLP
GNLLQVEPTQGMIPVTSDTKEITDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVATIRNQELQFTHILQEGGDYVTKD
ISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEVIGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGG
IVLIGGNAILPGMVELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSHQPISFGGM
LQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGLIGSMFDE
>Mature_456_residues
AREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKDGIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPG
NLLQVEPTQGMIPVTSDTKEITDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYTG
PRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVATIRNQELQFTHILQEGGDYVTKDI
SKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEVIGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGI
VLIGGNAILPGMVELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSHQPISFGGML
QKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGLIGSMFDE

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=387, Percent_Identity=31.7829457364341, Blast_Score=185, Evalue=5e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494
- InterPro:   IPR021873 [H]

Pfam domain/function: PF11983 DUF3484; PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 49476; Mature: 49344

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKDGIIVDIDAAATAIKSA
CCCCCCEEECCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHH
ISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEITDQDVENVVKSALTKSMT
HHHHHHHHCCEEEEEECCCCCCEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCC
PDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYTGPRTILHNLRKTVERAGVQV
CCCHHEEECCHHHHHHHHHHCCCCCCHHEEEEEECCEEEECHHHHHHHHHHHHHHHCCEE
ENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVATIRNQELQFTHILQEGGDYVTKD
HHHHHHHHHHHHHHHHCCHHHHCCEEEECCCCCEEEEECCCCCHHHHHHHHCCCCHHHHH
ISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEVIGEVEAVEVTEAYLSEIISARIKH
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
ILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMVELAQEVFGVRVKLYVPNQVGIRNPAF
HHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHCEEEEEEECCCCCCCCCHH
AHVISLSEFAGQLTEVNLLAQGAIKGENDLSHQPISFGGMLQKTAQFVQSTPVQPAPAPE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
VEPVAPTEPMADFQQASQNKPKLADRFRGLIGSMFDE
CCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKDGIIVDIDAAATAIKSA
CCCCCEEECCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHH
ISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEITDQDVENVVKSALTKSMT
HHHHHHHHCCEEEEEECCCCCCEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCC
PDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYTGPRTILHNLRKTVERAGVQV
CCCHHEEECCHHHHHHHHHHCCCCCCHHEEEEEECCEEEECHHHHHHHHHHHHHHHCCEE
ENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVATIRNQELQFTHILQEGGDYVTKD
HHHHHHHHHHHHHHHHCCHHHHCCEEEECCCCCEEEEECCCCCHHHHHHHHCCCCHHHHH
ISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEVIGEVEAVEVTEAYLSEIISARIKH
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
ILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMVELAQEVFGVRVKLYVPNQVGIRNPAF
HHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHCEEEEEEECCCCCCCCCHH
AHVISLSEFAGQLTEVNLLAQGAIKGENDLSHQPISFGGMLQKTAQFVQSTPVQPAPAPE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
VEPVAPTEPMADFQQASQNKPKLADRFRGLIGSMFDE
CCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10520745 [H]