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The map label for this gene is insK [H]

Identifier: 221232351

GI number: 221232351

Start: 1551391

End: 1552224

Strand: Reverse

Name: insK [H]

Synonym: SPN23F_16080

Alternate gene names: 221232351

Gene position: 1552224-1551391 (Counterclockwise)

Preceding gene: 221232352

Following gene: 221232345

Centisome position: 69.88

GC content: 36.09

Gene sequence:

>834_bases
ATGACTGAGTTTTCGTTAGATCTTCTTCTAAAAGCCATTAAACTAGCTCGTTCGACCTACTACTATCACTTGAAACAGCT
AGACAAAACAGATAAGGACCAAGAGCTTAAAGCTGAAATTCAATCCATTTTTATCGAACACAAGGGAAATTATGCTTATC
GTCGAATTCATTTAGAACTAAGAAATCGTGGTTATCTGGTAAATCATAAAAGAGTTCAAGGCTTGATGAAAGTACTCAAT
TTACAAGCTAAAATGCGACAGAAACGAAAATATTCTTCTCATAAAGGAGACGTTGGTAAGAAAGCAGAGAATCTCATTCA
AGGCCAATTTGAAGGCTCTAAAACAATGGAACAGTGCTACACAGATGTGACTGAATTTGCCATTCCAGCAAGTACTCAAA
AGCTTTACTTATCACCAGTTTTAGATGGCTTTAATAGCGAAATTATCGCCTATAATCTTTCAACTTCACCCAACTTAGAA
CAAGTACAAACAATGTTGGAACAGGCATTCACAGAGAAGCACTACGAGAATACGATTCTCCATAGTGACCAAGGCTGGCA
ATATCAACACGATTCTTATCATCGGTTCCTAGAGAGTAAGGGAATTCAAGCATCTATGTCACGCAAGGGAAACAGCCAAG
ACAACGGTATGATGGAATCTTTCTTTGGCATTTTAAAATCCGAAATGTTTTATGGCTATGAGAAAACATTTAAATCACTT
AACCAATTGGAACAAGCTATTGTAGACTATATTGATTACTACAACAATAAACGAATTAAGGTAAAACTAAAAGGACTTAG
TCCTGTGCAATACAGAACTAAATCCTTCGGATAA

Upstream 100 bases:

>100_bases
GAAAATGAGTACCTGAGAGCGGAGAATGCCATCCTAAAAAAGTTAAGAGAACTCCGATTGAAGGAGGAAAAAGAGAAAGA
CAGAAATTGTTTAAGAATTA

Downstream 100 bases:

>100_bases
ATTATTTGTCTAACTGTTTGGGGGCAGTACATTTTAACACTTGATACTATGCGTTTTATTGTGGGAAGATTTTCCTCATT
TTCTAGTGAAATTGAACTTT

Product: IS3-Spn1 orf B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MTEFSLDLLLKAIKLARSTYYYHLKQLDKTDKDQELKAEIQSIFIEHKGNYAYRRIHLELRNRGYLVNHKRVQGLMKVLN
LQAKMRQKRKYSSHKGDVGKKAENLIQGQFEGSKTMEQCYTDVTEFAIPASTQKLYLSPVLDGFNSEIIAYNLSTSPNLE
QVQTMLEQAFTEKHYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNSQDNGMMESFFGILKSEMFYGYEKTFKSL
NQLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG

Sequences:

>Translated_277_residues
MTEFSLDLLLKAIKLARSTYYYHLKQLDKTDKDQELKAEIQSIFIEHKGNYAYRRIHLELRNRGYLVNHKRVQGLMKVLN
LQAKMRQKRKYSSHKGDVGKKAENLIQGQFEGSKTMEQCYTDVTEFAIPASTQKLYLSPVLDGFNSEIIAYNLSTSPNLE
QVQTMLEQAFTEKHYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNSQDNGMMESFFGILKSEMFYGYEKTFKSL
NQLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG
>Mature_276_residues
TEFSLDLLLKAIKLARSTYYYHLKQLDKTDKDQELKAEIQSIFIEHKGNYAYRRIHLELRNRGYLVNHKRVQGLMKVLNL
QAKMRQKRKYSSHKGDVGKKAENLIQGQFEGSKTMEQCYTDVTEFAIPASTQKLYLSPVLDGFNSEIIAYNLSTSPNLEQ
VQTMLEQAFTEKHYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNSQDNGMMESFFGILKSEMFYGYEKTFKSLN
QLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: COG2801

COG function: function code L; Transposase and inactivated derivatives

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=255, Percent_Identity=29.0196078431373, Blast_Score=105, Evalue=4e-23,
Organism=Escherichia coli, GI1789981, Length=274, Percent_Identity=48.1751824817518, Blast_Score=268, Evalue=4e-73,
Organism=Escherichia coli, GI1788405, Length=282, Percent_Identity=28.3687943262411, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787263, Length=282, Percent_Identity=28.3687943262411, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786753, Length=282, Percent_Identity=28.3687943262411, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786570, Length=282, Percent_Identity=28.3687943262411, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786490, Length=282, Percent_Identity=28.3687943262411, Blast_Score=112, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 32416; Mature: 32285

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFSLDLLLKAIKLARSTYYYHLKQLDKTDKDQELKAEIQSIFIEHKGNYAYRRIHLEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEE
RNRGYLVNHKRVQGLMKVLNLQAKMRQKRKYSSHKGDVGKKAENLIQGQFEGSKTMEQCY
CCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHH
TDVTEFAIPASTQKLYLSPVLDGFNSEIIAYNLSTSPNLEQVQTMLEQAFTEKHYENTIL
HHHHHHCCCCCCHHEEHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEE
HSDQGWQYQHDSYHRFLESKGIQASMSRKGNSQDNGMMESFFGILKSEMFYGYEKTFKSL
ECCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
NQLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG
HHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCCC
>Mature Secondary Structure 
TEFSLDLLLKAIKLARSTYYYHLKQLDKTDKDQELKAEIQSIFIEHKGNYAYRRIHLEL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEE
RNRGYLVNHKRVQGLMKVLNLQAKMRQKRKYSSHKGDVGKKAENLIQGQFEGSKTMEQCY
CCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHH
TDVTEFAIPASTQKLYLSPVLDGFNSEIIAYNLSTSPNLEQVQTMLEQAFTEKHYENTIL
HHHHHHCCCCCCHHEEHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEE
HSDQGWQYQHDSYHRFLESKGIQASMSRKGNSQDNGMMESFFGILKSEMFYGYEKTFKSL
ECCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
NQLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG
HHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]