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The map label for this gene is tpiA [H]

Identifier: 221232335

GI number: 221232335

Start: 1535392

End: 1536150

Strand: Reverse

Name: tpiA [H]

Synonym: SPN23F_15910

Alternate gene names: 221232335

Gene position: 1536150-1535392 (Counterclockwise)

Preceding gene: 221232336

Following gene: 221232334

Centisome position: 69.15

GC content: 42.69

Gene sequence:

>759_bases
ATGTCACGTAAACCATTTATCGCTGGTAACTGGAAAATGAACAAAAATCCAGAAGAAGCTAAAGCATTCGTTGAAGCAGT
TGCATCAAAACTTCCTTCATCAGATCTTGTTGAAGCAGGTATCGCTGCTCCAGCTCTTGATTTGACAACTGTTCTTGCTG
TTGCAAAAGGCTCAAACCTTAAAGTTGCTGCTCAAAACTGCTACTTTGAAAATGCAGGTGCTTTCACTGGTGAAACTAGC
CCACAAGTTTTGAAAGAAATCGGTACTGACTACGTTGTTATCGGTCACTCAGAACGCCGTGACTACTTCCATGAAACTGA
CGAAGATATCAACAAAAAAGCAAAAGCAATCTTTGCGAACGGTATGCTTCCAATCATCTGTTGTGGTGAATCACTTGAAA
CTTACGAAGCTGGTAAAGCTGCTGAATTCGTAGGTGCTCAAGTATCTGCTGCATTGGCTGGATTGACTGCTGAACAAGTT
GCTGCCTCAGTTATCGCTTATGAGCCAATCTGGGCTATCGGTACTGGTAAATCAGCTTCACAAGACGATGCACAAAAAAT
GTGTAAAGTTGTTCGTGACGTTGTAGCTGCTGACTTTGGTCAAGAAGTCGCAGACAAAGTTCGTGTTCAATACGGTGGTT
CTGTTAAACCTGAAAATGTTGCTTCATACATGGCTTGCCCAGACGTTGACGGTGCCCTTGTAGGTGGTGCGTCACTTGAA
GCTGAAAGCTTCTTAGCTTTGCTTGACTTTGTAAAATAA

Upstream 100 bases:

>100_bases
TAATCCATGCAAGTAGGCTTGAAATCCGAGTAAGATTTGCAAGCTGTGTATAATTGTGATAGAATAAATAGAAAATAAAT
TGAAAAAAGAGGTATGTGAA

Downstream 100 bases:

>100_bases
TCAGTAAGTAGCAAAAGCTAGGTGGAACAGCATTCAGATGTCTGTTACATTTTTTATAGGAGAGCAAAGATTGAAAACAA
AAATTGGATTAGCAAGTATC

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAPALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETS
PQVLKEIGTDYVVIGHSERRDYFHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPENVASYMACPDVDGALVGGASLE
AESFLALLDFVK

Sequences:

>Translated_252_residues
MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAPALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETS
PQVLKEIGTDYVVIGHSERRDYFHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPENVASYMACPDVDGALVGGASLE
AESFLALLDFVK
>Mature_251_residues
SRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAPALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSP
QVLKEIGTDYVVIGHSERRDYFHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQVA
ASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPENVASYMACPDVDGALVGGASLEA
ESFLALLDFVK

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI226529917, Length=242, Percent_Identity=39.6694214876033, Blast_Score=160, Evalue=8e-40,
Organism=Homo sapiens, GI4507645, Length=249, Percent_Identity=38.9558232931727, Blast_Score=160, Evalue=9e-40,
Organism=Escherichia coli, GI1790353, Length=246, Percent_Identity=42.6829268292683, Blast_Score=197, Evalue=7e-52,
Organism=Caenorhabditis elegans, GI17536593, Length=257, Percent_Identity=42.4124513618677, Blast_Score=171, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6320255, Length=243, Percent_Identity=40.3292181069959, Blast_Score=179, Evalue=3e-46,
Organism=Drosophila melanogaster, GI28572008, Length=244, Percent_Identity=41.8032786885246, Blast_Score=175, Evalue=2e-44,
Organism=Drosophila melanogaster, GI28572006, Length=244, Percent_Identity=41.8032786885246, Blast_Score=175, Evalue=2e-44,
Organism=Drosophila melanogaster, GI28572004, Length=244, Percent_Identity=41.8032786885246, Blast_Score=175, Evalue=3e-44,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 26550; Mature: 26419

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAPALDLTTVLAVAKGSNL
CCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHCCCCE
KVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDYFHETDEDINKKAKAIFAN
EEEECCCEECCCCCCCCCCCHHHHHHHCCCEEEECCCHHHHHHCCCHHHHHHHHHHHHHC
GMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQVAASVIAYEPIWAIGTGKSAS
CCEEEEECCCCHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEECCCCCC
QDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPENVASYMACPDVDGALVGGASLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCEECCCCCC
AESFLALLDFVK
HHHHHHHHHHCC
>Mature Secondary Structure 
SRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAPALDLTTVLAVAKGSNL
CCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHCCCCE
KVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDYFHETDEDINKKAKAIFAN
EEEECCCEECCCCCCCCCCCHHHHHHHCCCEEEECCCHHHHHHCCCHHHHHHHHHHHHHC
GMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQVAASVIAYEPIWAIGTGKSAS
CCEEEEECCCCHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEECCCCCC
QDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPENVASYMACPDVDGALVGGASLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCEECCCCCC
AESFLALLDFVK
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA