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The map label for this gene is 221230904

Identifier: 221230904

GI number: 221230904

Start: 3158924

End: 3159856

Strand: Reverse

Name: 221230904

Synonym: MLBr_02640

Alternate gene names: NA

Gene position: 3159856-3158924 (Counterclockwise)

Preceding gene: 221230906

Following gene: 221230903

Centisome position: 96.69

GC content: 60.88

Gene sequence:

>933_bases
ATGCGAACCCACGACGACACCTGGGATATAAAGACCAGCGTCGGCACTACCGCGGTGATGGTGGCTGCTGCCCGAGCCGC
CGAAACCGATCGGCCTGACGCGCTGATTCGTGACCCCTATGCCAAACTGTTGGTGACCAACACCGGTGCCGGCGCCTTAT
GGGAAGCTATGCTTGACCCGTCGATGGTGGCCAAGGTGGAAGCCATCGACGCCGAAGCCGCAGCCATGGTCGAGCACATG
CGTAGCTACCAAGCAGTTCGGACGAATTTCTTCGACACCTACTTTAACAACGCTGTCATCGATGGAATCCGCCAGTTCGT
GATCTTGGCGTCGGGACTGGATTCCCGCGCTTACAGGCTGGATTGGCCGACTGGGACCACTGTATACGAGATCGATCAGC
CTAAGGTGTTGGCTTATAAGTCCACGACGTTGGCCGAACACGGCGTGACACCCACGGCCGATCGTCGTGAGGTGCCCATC
GACTTGCGTCAGGACTGGCCGCCGGCGCTGCGATCCGCGGGCTTTGACCCGTCAGCTCGAACGGCTTGGTTGGCCGAGGG
GTTGCTGATGTACTTGCCTGCCACTGCCCAGGACGGGTTGTTTACCGAGATCGGTGGGCTGAGCGCGGTCGGCAGTCGAA
TTGCGGTCGAAACCTCGCCTCTACACGGCGATGAGTGGCGCGAACAAATGCAGCTGCGGTTCAGAAGGGTGTCCGATGCG
CTTGGTTTCGAACAGGCTGTCGACGTGCAGGAGCTAATCTACCACGACGAAAATCGGGCGGTTGTTGCCGACTGGCTCAA
CCGCCACGGTTGGCGGGCTACTGCTCAAAGTGCTCCGGACGAGATGCGCCGGGTGGGCCGCTGGGGCGATGGTGTGCCGA
TGGCCGACGACAAGGATGCGTTCGCCGAGTTTGTGACCGCTCACCGGTTGTAA

Upstream 100 bases:

>100_bases
TTGGCCCGGCTTGGTTGGGGGTCCGATACCGGAAGACCTAGCCGGCGAGTCAGAATGTACCAAGACCTTTATAGTAGAGC
GGGAGCACGTAATGAGCACA

Downstream 100 bases:

>100_bases
TGACGCCCATCGCGGATGATTCCTGGGACATTGCAACCAGTGTCCAGGGACGTTCGCAGCACAAGTCTTGACCCGCTTAT
CCGAGACTTTTGCTGCGCGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MRTHDDTWDIKTSVGTTAVMVAAARAAETDRPDALIRDPYAKLLVTNTGAGALWEAMLDPSMVAKVEAIDAEAAAMVEHM
RSYQAVRTNFFDTYFNNAVIDGIRQFVILASGLDSRAYRLDWPTGTTVYEIDQPKVLAYKSTTLAEHGVTPTADRREVPI
DLRQDWPPALRSAGFDPSARTAWLAEGLLMYLPATAQDGLFTEIGGLSAVGSRIAVETSPLHGDEWREQMQLRFRRVSDA
LGFEQAVDVQELIYHDENRAVVADWLNRHGWRATAQSAPDEMRRVGRWGDGVPMADDKDAFAEFVTAHRL

Sequences:

>Translated_310_residues
MRTHDDTWDIKTSVGTTAVMVAAARAAETDRPDALIRDPYAKLLVTNTGAGALWEAMLDPSMVAKVEAIDAEAAAMVEHM
RSYQAVRTNFFDTYFNNAVIDGIRQFVILASGLDSRAYRLDWPTGTTVYEIDQPKVLAYKSTTLAEHGVTPTADRREVPI
DLRQDWPPALRSAGFDPSARTAWLAEGLLMYLPATAQDGLFTEIGGLSAVGSRIAVETSPLHGDEWREQMQLRFRRVSDA
LGFEQAVDVQELIYHDENRAVVADWLNRHGWRATAQSAPDEMRRVGRWGDGVPMADDKDAFAEFVTAHRL
>Mature_310_residues
MRTHDDTWDIKTSVGTTAVMVAAARAAETDRPDALIRDPYAKLLVTNTGAGALWEAMLDPSMVAKVEAIDAEAAAMVEHM
RSYQAVRTNFFDTYFNNAVIDGIRQFVILASGLDSRAYRLDWPTGTTVYEIDQPKVLAYKSTTLAEHGVTPTADRREVPI
DLRQDWPPALRSAGFDPSARTAWLAEGLLMYLPATAQDGLFTEIGGLSAVGSRIAVETSPLHGDEWREQMQLRFRRVSDA
LGFEQAVDVQELIYHDENRAVVADWLNRHGWRATAQSAPDEMRRVGRWGDGVPMADDKDAFAEFVTAHRL

Specific function: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity (Probable)

COG id: COG3315

COG function: function code Q; O-Methyltransferase involved in polyketide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0677 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2640_MYCLE (Q9CCZ4)

Other databases:

- EMBL:   AL583926
- PIR:   F87239
- RefSeq:   NP_302690.1
- PDB:   2CKD
- PDB:   2UYO
- PDB:   2UYQ
- PDBsum:   2CKD
- PDBsum:   2UYO
- PDBsum:   2UYQ
- ProteinModelPortal:   Q9CCZ4
- SMR:   Q9CCZ4
- EnsemblBacteria:   EBMYCT00000028855
- GeneID:   910852
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML2640
- NMPDR:   fig|272631.1.peg.1562
- Leproma:   ML2640
- GeneTree:   EBGT00050000015698
- HOGENOM:   HBG570783
- OMA:   LAYKSAT
- ProtClustDB:   CLSK790300
- BioCyc:   MLEP272631:ML2640-MONOMER
- InterPro:   IPR011610
- InterPro:   IPR007213
- TIGRFAMs:   TIGR00027

Pfam domain/function: PF04072 LCM

EC number: NA

Molecular weight: Translated: 34454; Mature: 34454

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: BINDING 132-132

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTHDDTWDIKTSVGTTAVMVAAARAAETDRPDALIRDPYAKLLVTNTGAGALWEAMLDP
CCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCHHHHCCCEEEEEECCCCHHHHHHHHCH
SMVAKVEAIDAEAAAMVEHMRSYQAVRTNFFDTYFNNAVIDGIRQFVILASGLDSRAYRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
DWPTGTTVYEIDQPKVLAYKSTTLAEHGVTPTADRREVPIDLRQDWPPALRSAGFDPSAR
ECCCCCEEEEECCCEEEEEECCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHH
TAWLAEGLLMYLPATAQDGLFTEIGGLSAVGSRIAVETSPLHGDEWREQMQLRFRRVSDA
HHHHHCCHHHEECCCCCCCCHHHHCCHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
LGFEQAVDVQELIYHDENRAVVADWLNRHGWRATAQSAPDEMRRVGRWGDGVPMADDKDA
HCHHHHCCHHHHHHCCCCCEEHHHHHHCCCCCCHHHCCHHHHHHHCCCCCCCCCCCCHHH
FAEFVTAHRL
HHHHHHHHCC
>Mature Secondary Structure
MRTHDDTWDIKTSVGTTAVMVAAARAAETDRPDALIRDPYAKLLVTNTGAGALWEAMLDP
CCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCHHHHCCCEEEEEECCCCHHHHHHHHCH
SMVAKVEAIDAEAAAMVEHMRSYQAVRTNFFDTYFNNAVIDGIRQFVILASGLDSRAYRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
DWPTGTTVYEIDQPKVLAYKSTTLAEHGVTPTADRREVPIDLRQDWPPALRSAGFDPSAR
ECCCCCEEEEECCCEEEEEECCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHH
TAWLAEGLLMYLPATAQDGLFTEIGGLSAVGSRIAVETSPLHGDEWREQMQLRFRRVSDA
HHHHHCCHHHEECCCCCCCCHHHHCCHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
LGFEQAVDVQELIYHDENRAVVADWLNRHGWRATAQSAPDEMRRVGRWGDGVPMADDKDA
HCHHHHCCHHHHHHCCCCCEEHHHHHHCCCCCCHHHCCHHHHHHHCCCCCCCCCCCCHHH
FAEFVTAHRL
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002