| Definition | Mycobacterium leprae Br4923 chromosome, complete genome. |
|---|---|
| Accession | NC_011896 |
| Length | 3,268,071 |
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The map label for this gene is ppsA [H]
Identifier: 221230750
GI number: 221230750
Start: 2815992
End: 2821607
Strand: Reverse
Name: ppsA [H]
Synonym: MLBr_02357
Alternate gene names: 221230750
Gene position: 2821607-2815992 (Counterclockwise)
Preceding gene: 221230751
Following gene: 221230749
Centisome position: 86.34
GC content: 59.67
Gene sequence:
>5616_bases ATGACGGCGAGCATTGGTAGCGAAGCTGACCTTTGCCACTGGCTAGTCAACTACTTGGTGACTAATATCGGCTGCACACC GGATGAAGTCGATCTTAATCTATCGTTGACCGACTTGGGTATGAGCTCCCGTGATGCAGTTGTGCTCTCCGGGGAATTGA CCGATTTGTTGGGTAAGACCGTATCCCCGATTGACTTCTGGGAGCATCCGACGATCAACGCGCTGGCCGCCTATCTCATT GCTCCCGCACCTGACCCCGAATCAGAATCGGCGCCACGGCGCTCGGTCCAGGGTGCACTCGAGGAGCCGATCGCTGTCAT CGGGATGGGGTGTCGTTTCCCAGGGGGGATATCTGGTCCAGAAGCGTTGTGGCAGTTTCTGTGTGACCGTCGTTCCTCCA TCGGACAGGTTCCCAATGAACGGTGGGAGCTCTTCGACGACGGCTCGCCGGAAGTAAAAGCACTGCTCGCCCGTACTACG CGGTGGGGGTCATTCTTGGAGGATATTGACGCCTTTGACTCGGAATTTTTCGAGATCTCACCCAGCGAGGCTGACAAGAT GGATCCGCAGCAGCGCCTTCTGCTGGAAGTGGCTTGGGAGGCGTTGGAGCACGCGGGAATTTCGTCCAACTCGCTGCGTC GTTCGCAAACAGGAGTATTCGCCGGATCGTGCCTGAGCGAATATGGTGCTATCGCTTCCACCGATCTCTCCCAAGTGGAT GGCTGGAGCAACACGGGTGGCGCGATGAGCATCATAGCGAACCGCCTTTCGTATTTCCTCGACTTACGTGGTCCATCGGT GGCGGTTGATACGGCGTGCTCGTCGTCGTTGGTAGCGATCCACTTAGCCTGCCAAAGCCTGCGGACCGCGGATGCCAACC TGGCTATTGCGGCGGGCGTGAATTTGCTATTGTCTCCGGCCGTATTTCGTGGCTTCGACCAGGTCGGGGCGTTGTCGCCT ACCGGTTGTTGCCGCGCGTTCGATGCTGCGGCGGACGGGTTTGTGCGCGGTGAAGGTGCTGGCGTAGTGGTGCTTAAACG GTTGACCGATGCGCAGCGCGACGGTGATCGGGTGCTTGCCATTATCCGCGGTTCTGCTGTCAATCAGGATGGCCGCTCCA ACGGGCTGATGGCTCCTAACCCGGCGGCCCAAGTAGCGGTTCTGCGCACCGCGTATGCCAACGCAGCAATGCCACCGACT GCCATTGACTACGTCGAAACTCATGGGACCGGGACTCTGTTGGGAGATCCGATAGAAGCGCGCGCTTTGGGTGCGGTGCT GGGTCGGGGACGTGCCGAGGATTCTCCGCTACTGATCGGGGCTGTTAAGACTAACCTGGGTCACTTGGAGGCTGCTGCGG GCATCGCCGGCTTCATCAAGACAGTGTTGGCGGTGCAGCGTGGCCAGATTCCACCGAATCAGCGTTTTGAAAGCCCGAAC CTGCATATTCCTTTTGCTGAGTTGCGTATGAAAGTTGTTGATAAGCATATGGAATGGCCGGATACAGGGCATCTGCGGCG CGCGGCGGTGTCATCGTTTGGCTTCGGTGGGACGAACGCGCATGTTGTCATTGAGCAGGGTCCTGAGCTGACACCGGTCA CAGAATGCAGTTCCAACACTGCGGTGTCGACGTTGGTGGTGACGGGTAAGACGGCGTCGCGGGTGGCAGCGATGGCGGGG ATGCTGGCCGATTGGGTTGAGGGGCCCGGTGCTGAAGTGGCGTTGGCTGATGTGGCCCATACATTGAATCATCACCGGTC GCGGCACGCCAAGTTCGGCACCGTGGTTGCCCGTGATCGGATCCAGGCAGTGGCTGGATTGCGGGCGTTGGCCGCCGGCA AACAGGCGCCCGGTGTGGTCGGGCAGCAGGATGGCACACCTGGGTCAGGAACGGTGTTTGTGTACTCGGGACGTGGTTCG CAGTGGGCGGGGATGGGGCGTCAATTGCTGGCCGATGAACCGGCTTTCACGGCCGCGGTTGCCGAGTTGGAACCGGTGTT TGTTGTCCACGCCGGTTTCTCGTTGCACGATGTGCTCGCTAATGGCAAAGAACTGGTTGGTATCGAGCAGATCCAGCTGG GGTTAATCGGCATGCAACTGACGCTGACTGAGTTGTGGCGTTCCTATGGGGTGCAACCTGATTTGGTGATCGGGCATTCG CTGGGTGAGGTGGCCGCCGCCGTGGTGGCTGGGGCGCTTACCGCCGCTGAGGGGCTGCGGGTGACAGCCACTCGGTCGCG GCTGATGGCCCCGCTGTCTGGGCAGGGCGGTATGGCACTGCTCGAACTCGACGCGGTCGAGACGGAGGCGTTGATTGTCG ACTACTCGCAGGTGACATTGGCGATTTACAATTCGCCGCGCCAAACGGTGATTGCCGGGCCCACTGAACAGATCGATGAG TTGATTGACCGGGTGCGCGCGCAGAATCGGTTTGCCAGTCGGGTCAATATTGAAGTGGCCCCCCACAATCCGGCGATGGA TGCGCTGCAGCCGCAGATGCGTTCCGAGCTCGCCGATGTGGCCCCACGGACTCCGACGATTCCGATCCTTTCCACCACCT ATGCTGACCTTGGCTCGTGCCCGGTGTTCGATGCCCAGCACTGGGCCACCAACATGCGCAACCCAGTGCATTTCCAGCAG GCCATCATGACCGCTGGAACTGACCACCGCACTTTCATCGAAATCAGTGCACACCCGCTGCTGACCCAAGCCATTACTGA CACCCTGCACGGTACCCGGTGCATCAGCATTGGGACCCTGCAACGCGATGCCGACGACACCGTCACCTTTCACACCAACC TCAACAACGTCCACACCGTCCACCCACCACACACCCCTCATCCTGCGGAACCACACGTAACTATCCCCAGCACTCCCTGG CAGCACACCCGCCACTGGATCCCTCGGAAACGTTCGGTCAACTCTATTGGATTGGCACCCCAGGTGGGCACGCTACTTGG CCAACACACCGCGGTCTCAGGGATTCTTCCTATCCACTTGTGGCAGGCGCGGCTAGCGCCGCAGGCCAAGCCGTACAGGG GTTGGCATCGAGTCCACGGTGTCGAGGTGGTCCCTGCTTCTATTGTGCTGCGCACAATCCTTTGTGCTGCAGCAGAATTG GGTTATTCTACGCTATTCGAGATCCGATTCGAGCAACCCATTTTCGCTAATCTCCCCCGTTTGATCCAGGTCGTCGTCGA TAACCAATTGATCAGCCTGGCCTCAAGTCCGGCCACCGAAACTCCTCAGCACCGGTGGACGCGGCATGTGACCGCGCAGC TTTCCTCAGCATCGGCGCGTTCCGCGGTTCCATCGGACCACCCGGATCAGATTAATGGTCATCTTGAGGTGATTTCGGAC CCGATTCCCGACGTAGCTTCGCTGCTCGCGCTGTGTGGGGTTGACGGCCTGCCTTTCGAGTGGTCCGTCAAGTCATGGGC GAAAAAGACGCAGCAGTCAACCAGCCGCACGGTTGAGATCGAATTTCCCGATACCCTGCCCGACGGGGCGATCGCGCCGC TACTCGACGCCGCAATTCTTATCCCAGCGCTGGCGGACGTTACCGAAACGCAATTTTACGTGCCGGCAAGCATTAAGCAG GTGTGGTTAGGCGACACCGCTACAGGACCATGTGGTGCGGTGACGCTAAATCGCACTGCTTGCGACGACGACGGGATTAC CGTCGATGTCACCGTCGCCGACGGCAGCGGTGTGCCGTTGGCGTTGATGCGGTCACTTCGGTATCGAGCGTTAGACCTTG ACAACGCGCAACAGGACTATTCGACTGTTTTCGTTGAATCCCATGTGGATGCCCTTACAGATGCCAGGAATTTCGTGCAT GCGATCGATTGGCAACCGCGGACCGACCTGGATTGCTCCAACACCCCGGTAGCCAGTTCGGGGTCTGTCGCGGTAATCGG TGATGCTCGCGCTGGGTTTGGCTTGCTGCTCAAGGAGGCGGGCTATACGTTGGCTGCGCCTGCTGATGGGGTGTCTGAGG TACGTTACGTTGTTTATGTCGCGGATCCCCACCCGGCAACCACTGCCGAGACCGACGTCGACTTTGCCGTGCGAATCACT GCTGAGATCAGCGATTTGGTGAGGGCTTTGGCGAAGCGGGAGCCGGGCAAGCCTGTAGCACTGTGGATCGTCACACGCGG AGTTTACGAATCGGTGGCCTCGTCCGCGTTACGCCAGAGCTTCCTGTGGGGTTTTGGGGGCGTCATCGCCGCGGAGCATC CTGAGATGTGGGGTGGACTCGTCGATCTTGCGGCTAGTGCTCTTGGAGCCGATCGCGACGACATTCTCGACCAATTTGGG CCGACGCTTGCCAGTCTGCTTCAAACACCGACCAGGTCGATCGTGGTATTACGTGACGGCGTCGTGCTTGCCCCGACATT GGTGCCGATCCGAAGTGAGCCGGTGCGCAAATCTTTGCAATGCAAGTCCGATGGGGCCTACCTCATCACCGGCGGAATGG GTGCACTTGGTCTGCTGATGGCTGATTGGCTCGCTGACCGCGGCGCTCGTCGACTGGTGTTGATGGGCCGTACACCGTTA CCGCCAAGGCGGGACTGGGAACTCGACACTCTCGATGCCGGACTGCGTCAGAAGATCGATGCTATTTGCGCCCTTGAGAT GCGGGGAGTGACAGTCGAAGCCGTCGCGGTTGACGTCGGACACCACGACGATGTGCAGGCCTTGTTGGCCAAGCGTGACC GTGACGGCGCCGCGCCGATCCGGGGGATCATTCATGCGGCAGGCGTTACGAATGACCAACTAGTGACGAACATGACCGAC GATCCGGTTCGTCAAGTTATGTGGCCTAAGATCGCCGGCTGCCAGGTGCTGCACGAGGCCTTTCCACCTGGCAGTGTGGA CTTTTTCTACTTGACCTCCTCGGCCGCAGGAATATTCGGCATCCCGGGTCAGGGCTCTTACGCTGCCGCCAATTCCTACC TGGACGCGTTGGCGCGTACGCGTCGCCAGCAGGGCTGCCACACTATGAGCATCGACTGGGTAGCCTGGCGCGGGCTCGGA TTCGCCGCTAACGCGCAGATTGTCAGTGATGAGTTGCAGCGAATGGGGTCGCGTGATATCACGCCTTCGGAAGCGTTCAC CGCGTGGGAGTACGTCGATGCCTACGACGTTGCACAGGCGGTTGTATTGCCGGTCCCTAGGTCCTACGGGTCCGCCGGAT CGACTGCCGGGGATAGCTATCTAGTCCCGGCACGAAATTGGTCGCAGATGGAGGCCGCCGAGGTACGGAAGGAGCTTGAA AGTGGCTTACGGACCATCATCGCCGCAGAGCTCCGGGTGGCCGAGGCGGAGCTGGATACAGATCGACCATTCGCCGAACT TGGACTCAACTCCCTTATGGCAATGGCGATTCGGCGTGAAGCCGAGCAATTCATTGGTATAGAGCTGTCGGCAATCATGC TGTTCAACCATCCAACCGTTGCGTTACTAGCCGCGTATCTGACAAAAGTTGTCGCACCGCAGCACGATTCGCAAGGAGAC GAGATGGCCGCCTTATCCGCCTCGGCAGGAGGCGTATTAGATAGTCTCTTCGACCGCATCGAATCGACATCGACTGAGGC CGAAGGGTTGGTGTAA
Upstream 100 bases:
>100_bases CACCGGGCTCAATCCCGATCACCACAAGCGGCAAGGTCCGACGTTCGGCCTGTGTCGAACGTTATCGCAGTGACGGATTC AAACGACTGGACGTGACGGT
Downstream 100 bases:
>100_bases ATGCGGACCGCTTTCAGCCGGATTTCCGGCATGACCACGCAGCAGCGCGCGGCTCTTATCGAAGAATTCACCAAGCTCTC TCGGATTGCTGTGGCAGAGC
Product: polyketide synthase
Products: [acyl carrier protein]; acetoacetyl-ACP; CO2; [acyl carrier protein]; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 1871; Mature: 1870
Protein sequence:
>1871_residues MTASIGSEADLCHWLVNYLVTNIGCTPDEVDLNLSLTDLGMSSRDAVVLSGELTDLLGKTVSPIDFWEHPTINALAAYLI APAPDPESESAPRRSVQGALEEPIAVIGMGCRFPGGISGPEALWQFLCDRRSSIGQVPNERWELFDDGSPEVKALLARTT RWGSFLEDIDAFDSEFFEISPSEADKMDPQQRLLLEVAWEALEHAGISSNSLRRSQTGVFAGSCLSEYGAIASTDLSQVD GWSNTGGAMSIIANRLSYFLDLRGPSVAVDTACSSSLVAIHLACQSLRTADANLAIAAGVNLLLSPAVFRGFDQVGALSP TGCCRAFDAAADGFVRGEGAGVVVLKRLTDAQRDGDRVLAIIRGSAVNQDGRSNGLMAPNPAAQVAVLRTAYANAAMPPT AIDYVETHGTGTLLGDPIEARALGAVLGRGRAEDSPLLIGAVKTNLGHLEAAAGIAGFIKTVLAVQRGQIPPNQRFESPN LHIPFAELRMKVVDKHMEWPDTGHLRRAAVSSFGFGGTNAHVVIEQGPELTPVTECSSNTAVSTLVVTGKTASRVAAMAG MLADWVEGPGAEVALADVAHTLNHHRSRHAKFGTVVARDRIQAVAGLRALAAGKQAPGVVGQQDGTPGSGTVFVYSGRGS QWAGMGRQLLADEPAFTAAVAELEPVFVVHAGFSLHDVLANGKELVGIEQIQLGLIGMQLTLTELWRSYGVQPDLVIGHS LGEVAAAVVAGALTAAEGLRVTATRSRLMAPLSGQGGMALLELDAVETEALIVDYSQVTLAIYNSPRQTVIAGPTEQIDE LIDRVRAQNRFASRVNIEVAPHNPAMDALQPQMRSELADVAPRTPTIPILSTTYADLGSCPVFDAQHWATNMRNPVHFQQ AIMTAGTDHRTFIEISAHPLLTQAITDTLHGTRCISIGTLQRDADDTVTFHTNLNNVHTVHPPHTPHPAEPHVTIPSTPW QHTRHWIPRKRSVNSIGLAPQVGTLLGQHTAVSGILPIHLWQARLAPQAKPYRGWHRVHGVEVVPASIVLRTILCAAAEL GYSTLFEIRFEQPIFANLPRLIQVVVDNQLISLASSPATETPQHRWTRHVTAQLSSASARSAVPSDHPDQINGHLEVISD PIPDVASLLALCGVDGLPFEWSVKSWAKKTQQSTSRTVEIEFPDTLPDGAIAPLLDAAILIPALADVTETQFYVPASIKQ VWLGDTATGPCGAVTLNRTACDDDGITVDVTVADGSGVPLALMRSLRYRALDLDNAQQDYSTVFVESHVDALTDARNFVH AIDWQPRTDLDCSNTPVASSGSVAVIGDARAGFGLLLKEAGYTLAAPADGVSEVRYVVYVADPHPATTAETDVDFAVRIT AEISDLVRALAKREPGKPVALWIVTRGVYESVASSALRQSFLWGFGGVIAAEHPEMWGGLVDLAASALGADRDDILDQFG PTLASLLQTPTRSIVVLRDGVVLAPTLVPIRSEPVRKSLQCKSDGAYLITGGMGALGLLMADWLADRGARRLVLMGRTPL PPRRDWELDTLDAGLRQKIDAICALEMRGVTVEAVAVDVGHHDDVQALLAKRDRDGAAPIRGIIHAAGVTNDQLVTNMTD DPVRQVMWPKIAGCQVLHEAFPPGSVDFFYLTSSAAGIFGIPGQGSYAAANSYLDALARTRRQQGCHTMSIDWVAWRGLG FAANAQIVSDELQRMGSRDITPSEAFTAWEYVDAYDVAQAVVLPVPRSYGSAGSTAGDSYLVPARNWSQMEAAEVRKELE SGLRTIIAAELRVAEAELDTDRPFAELGLNSLMAMAIRREAEQFIGIELSAIMLFNHPTVALLAAYLTKVVAPQHDSQGD EMAALSASAGGVLDSLFDRIESTSTEAEGLV
Sequences:
>Translated_1871_residues MTASIGSEADLCHWLVNYLVTNIGCTPDEVDLNLSLTDLGMSSRDAVVLSGELTDLLGKTVSPIDFWEHPTINALAAYLI APAPDPESESAPRRSVQGALEEPIAVIGMGCRFPGGISGPEALWQFLCDRRSSIGQVPNERWELFDDGSPEVKALLARTT RWGSFLEDIDAFDSEFFEISPSEADKMDPQQRLLLEVAWEALEHAGISSNSLRRSQTGVFAGSCLSEYGAIASTDLSQVD GWSNTGGAMSIIANRLSYFLDLRGPSVAVDTACSSSLVAIHLACQSLRTADANLAIAAGVNLLLSPAVFRGFDQVGALSP TGCCRAFDAAADGFVRGEGAGVVVLKRLTDAQRDGDRVLAIIRGSAVNQDGRSNGLMAPNPAAQVAVLRTAYANAAMPPT AIDYVETHGTGTLLGDPIEARALGAVLGRGRAEDSPLLIGAVKTNLGHLEAAAGIAGFIKTVLAVQRGQIPPNQRFESPN LHIPFAELRMKVVDKHMEWPDTGHLRRAAVSSFGFGGTNAHVVIEQGPELTPVTECSSNTAVSTLVVTGKTASRVAAMAG MLADWVEGPGAEVALADVAHTLNHHRSRHAKFGTVVARDRIQAVAGLRALAAGKQAPGVVGQQDGTPGSGTVFVYSGRGS QWAGMGRQLLADEPAFTAAVAELEPVFVVHAGFSLHDVLANGKELVGIEQIQLGLIGMQLTLTELWRSYGVQPDLVIGHS LGEVAAAVVAGALTAAEGLRVTATRSRLMAPLSGQGGMALLELDAVETEALIVDYSQVTLAIYNSPRQTVIAGPTEQIDE LIDRVRAQNRFASRVNIEVAPHNPAMDALQPQMRSELADVAPRTPTIPILSTTYADLGSCPVFDAQHWATNMRNPVHFQQ AIMTAGTDHRTFIEISAHPLLTQAITDTLHGTRCISIGTLQRDADDTVTFHTNLNNVHTVHPPHTPHPAEPHVTIPSTPW QHTRHWIPRKRSVNSIGLAPQVGTLLGQHTAVSGILPIHLWQARLAPQAKPYRGWHRVHGVEVVPASIVLRTILCAAAEL GYSTLFEIRFEQPIFANLPRLIQVVVDNQLISLASSPATETPQHRWTRHVTAQLSSASARSAVPSDHPDQINGHLEVISD PIPDVASLLALCGVDGLPFEWSVKSWAKKTQQSTSRTVEIEFPDTLPDGAIAPLLDAAILIPALADVTETQFYVPASIKQ VWLGDTATGPCGAVTLNRTACDDDGITVDVTVADGSGVPLALMRSLRYRALDLDNAQQDYSTVFVESHVDALTDARNFVH AIDWQPRTDLDCSNTPVASSGSVAVIGDARAGFGLLLKEAGYTLAAPADGVSEVRYVVYVADPHPATTAETDVDFAVRIT AEISDLVRALAKREPGKPVALWIVTRGVYESVASSALRQSFLWGFGGVIAAEHPEMWGGLVDLAASALGADRDDILDQFG PTLASLLQTPTRSIVVLRDGVVLAPTLVPIRSEPVRKSLQCKSDGAYLITGGMGALGLLMADWLADRGARRLVLMGRTPL PPRRDWELDTLDAGLRQKIDAICALEMRGVTVEAVAVDVGHHDDVQALLAKRDRDGAAPIRGIIHAAGVTNDQLVTNMTD DPVRQVMWPKIAGCQVLHEAFPPGSVDFFYLTSSAAGIFGIPGQGSYAAANSYLDALARTRRQQGCHTMSIDWVAWRGLG FAANAQIVSDELQRMGSRDITPSEAFTAWEYVDAYDVAQAVVLPVPRSYGSAGSTAGDSYLVPARNWSQMEAAEVRKELE SGLRTIIAAELRVAEAELDTDRPFAELGLNSLMAMAIRREAEQFIGIELSAIMLFNHPTVALLAAYLTKVVAPQHDSQGD EMAALSASAGGVLDSLFDRIESTSTEAEGLV >Mature_1870_residues TASIGSEADLCHWLVNYLVTNIGCTPDEVDLNLSLTDLGMSSRDAVVLSGELTDLLGKTVSPIDFWEHPTINALAAYLIA PAPDPESESAPRRSVQGALEEPIAVIGMGCRFPGGISGPEALWQFLCDRRSSIGQVPNERWELFDDGSPEVKALLARTTR WGSFLEDIDAFDSEFFEISPSEADKMDPQQRLLLEVAWEALEHAGISSNSLRRSQTGVFAGSCLSEYGAIASTDLSQVDG WSNTGGAMSIIANRLSYFLDLRGPSVAVDTACSSSLVAIHLACQSLRTADANLAIAAGVNLLLSPAVFRGFDQVGALSPT GCCRAFDAAADGFVRGEGAGVVVLKRLTDAQRDGDRVLAIIRGSAVNQDGRSNGLMAPNPAAQVAVLRTAYANAAMPPTA IDYVETHGTGTLLGDPIEARALGAVLGRGRAEDSPLLIGAVKTNLGHLEAAAGIAGFIKTVLAVQRGQIPPNQRFESPNL HIPFAELRMKVVDKHMEWPDTGHLRRAAVSSFGFGGTNAHVVIEQGPELTPVTECSSNTAVSTLVVTGKTASRVAAMAGM LADWVEGPGAEVALADVAHTLNHHRSRHAKFGTVVARDRIQAVAGLRALAAGKQAPGVVGQQDGTPGSGTVFVYSGRGSQ WAGMGRQLLADEPAFTAAVAELEPVFVVHAGFSLHDVLANGKELVGIEQIQLGLIGMQLTLTELWRSYGVQPDLVIGHSL GEVAAAVVAGALTAAEGLRVTATRSRLMAPLSGQGGMALLELDAVETEALIVDYSQVTLAIYNSPRQTVIAGPTEQIDEL IDRVRAQNRFASRVNIEVAPHNPAMDALQPQMRSELADVAPRTPTIPILSTTYADLGSCPVFDAQHWATNMRNPVHFQQA IMTAGTDHRTFIEISAHPLLTQAITDTLHGTRCISIGTLQRDADDTVTFHTNLNNVHTVHPPHTPHPAEPHVTIPSTPWQ HTRHWIPRKRSVNSIGLAPQVGTLLGQHTAVSGILPIHLWQARLAPQAKPYRGWHRVHGVEVVPASIVLRTILCAAAELG YSTLFEIRFEQPIFANLPRLIQVVVDNQLISLASSPATETPQHRWTRHVTAQLSSASARSAVPSDHPDQINGHLEVISDP IPDVASLLALCGVDGLPFEWSVKSWAKKTQQSTSRTVEIEFPDTLPDGAIAPLLDAAILIPALADVTETQFYVPASIKQV WLGDTATGPCGAVTLNRTACDDDGITVDVTVADGSGVPLALMRSLRYRALDLDNAQQDYSTVFVESHVDALTDARNFVHA IDWQPRTDLDCSNTPVASSGSVAVIGDARAGFGLLLKEAGYTLAAPADGVSEVRYVVYVADPHPATTAETDVDFAVRITA EISDLVRALAKREPGKPVALWIVTRGVYESVASSALRQSFLWGFGGVIAAEHPEMWGGLVDLAASALGADRDDILDQFGP TLASLLQTPTRSIVVLRDGVVLAPTLVPIRSEPVRKSLQCKSDGAYLITGGMGALGLLMADWLADRGARRLVLMGRTPLP PRRDWELDTLDAGLRQKIDAICALEMRGVTVEAVAVDVGHHDDVQALLAKRDRDGAAPIRGIIHAAGVTNDQLVTNMTDD PVRQVMWPKIAGCQVLHEAFPPGSVDFFYLTSSAAGIFGIPGQGSYAAANSYLDALARTRRQQGCHTMSIDWVAWRGLGF AANAQIVSDELQRMGSRDITPSEAFTAWEYVDAYDVAQAVVLPVPRSYGSAGSTAGDSYLVPARNWSQMEAAEVRKELES GLRTIIAAELRVAEAELDTDRPFAELGLNSLMAMAIRREAEQFIGIELSAIMLFNHPTVALLAAYLTKVVAPQHDSQGDE MAALSASAGGVLDSLFDRIESTSTEAEGLV
Specific function: Polyketide synthase involved in phenolpthiocerol synthesis [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 acyl carrier domains [H]
Homologues:
Organism=Homo sapiens, GI41872631, Length=900, Percent_Identity=30.6666666666667, Blast_Score=345, Evalue=2e-94, Organism=Homo sapiens, GI8923559, Length=441, Percent_Identity=27.437641723356, Blast_Score=118, Evalue=4e-26, Organism=Escherichia coli, GI1787337, Length=285, Percent_Identity=29.8245614035088, Blast_Score=114, Evalue=5e-26, Organism=Escherichia coli, GI1788663, Length=273, Percent_Identity=29.3040293040293, Blast_Score=95, Evalue=3e-20, Organism=Escherichia coli, GI1787334, Length=295, Percent_Identity=27.4576271186441, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI212642053, Length=847, Percent_Identity=30.814639905549, Blast_Score=352, Evalue=1e-96, Organism=Caenorhabditis elegans, GI17550940, Length=523, Percent_Identity=34.225621414914, Blast_Score=240, Evalue=5e-63, Organism=Caenorhabditis elegans, GI71983541, Length=447, Percent_Identity=28.6353467561521, Blast_Score=135, Evalue=2e-31, Organism=Caenorhabditis elegans, GI71983535, Length=272, Percent_Identity=33.4558823529412, Blast_Score=127, Evalue=7e-29, Organism=Saccharomyces cerevisiae, GI6320904, Length=447, Percent_Identity=25.7270693512304, Blast_Score=121, Evalue=9e-28, Organism=Drosophila melanogaster, GI19920632, Length=1010, Percent_Identity=28.9108910891089, Blast_Score=343, Evalue=5e-94, Organism=Drosophila melanogaster, GI221330659, Length=1007, Percent_Identity=28.798411122145, Blast_Score=343, Evalue=6e-94, Organism=Drosophila melanogaster, GI24581345, Length=890, Percent_Identity=30.3370786516854, Blast_Score=332, Evalue=1e-90, Organism=Drosophila melanogaster, GI24644341, Length=444, Percent_Identity=28.3783783783784, Blast_Score=127, Evalue=7e-29,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001227 - InterPro: IPR009081 - InterPro: IPR014043 - InterPro: IPR016035 - InterPro: IPR000794 - InterPro: IPR002198 - InterPro: IPR018201 - InterPro: IPR014031 - InterPro: IPR014030 - InterPro: IPR016036 - InterPro: IPR016040 - InterPro: IPR006163 - InterPro: IPR020842 - InterPro: IPR020801 - InterPro: IPR020841 - InterPro: IPR020806 - InterPro: IPR006162 - InterPro: IPR016039 - InterPro: IPR016038 [H]
Pfam domain/function: PF00698 Acyl_transf_1; PF00106 adh_short; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF00550 PP-binding [H]
EC number: 2.3.1.41 [C]
Molecular weight: Translated: 199735; Mature: 199604
Theoretical pI: Translated: 4.97; Mature: 4.97
Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00606 B_KETOACYL_SYNTHASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTASIGSEADLCHWLVNYLVTNIGCTPDEVDLNLSLTDLGMSSRDAVVLSGELTDLLGKT CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCEEEEECCHHHHHCCC VSPIDFWEHPTINALAAYLIAPAPDPESESAPRRSVQGALEEPIAVIGMGCRFPGGISGP CCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCH EALWQFLCDRRSSIGQVPNERWELFDDGSPEVKALLARTTRWGSFLEDIDAFDSEFFEIS HHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEC PSEADKMDPQQRLLLEVAWEALEHAGISSNSLRRSQTGVFAGSCLSEYGAIASTDLSQVD CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHCCCCCCCCHHHCC GWSNTGGAMSIIANRLSYFLDLRGPSVAVDTACSSSLVAIHLACQSLRTADANLAIAAGV CCCCCCHHHHHHHHHHHHHEECCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEECCH NLLLSPAVFRGFDQVGALSPTGCCRAFDAAADGFVRGEGAGVVVLKRLTDAQRDGDRVLA HHHHCHHHHHCHHHHCCCCCCHHHHHHHHHCCCCEECCCCCEEEEEHHHHCCCCCCEEEE IIRGSAVNQDGRSNGLMAPNPAAQVAVLRTAYANAAMPPTAIDYVETHGTGTLLGDPIEA EEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHEEECCCCCCCCCCHHH RALGAVLGRGRAEDSPLLIGAVKTNLGHLEAAAGIAGFIKTVLAVQRGQIPPNQRFESPN HHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC LHIPFAELRMKVVDKHMEWPDTGHLRRAAVSSFGFGGTNAHVVIEQGPELTPVTECSSNT CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHCCCCCC AVSTLVVTGKTASRVAAMAGMLADWVEGPGAEVALADVAHTLNHHRSRHAKFGTVVARDR EEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH IQAVAGLRALAAGKQAPGVVGQQDGTPGSGTVFVYSGRGSQWAGMGRQLLADEPAFTAAV HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHCCHHHHCCCCHHHHHH AELEPVFVVHAGFSLHDVLANGKELVGIEQIQLGLIGMQLTLTELWRSYGVQPDLVIGHS HHCCEEEEEECCCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCC LGEVAAAVVAGALTAAEGLRVTATRSRLMAPLSGQGGMALLELDAVETEALIVDYSQVTL HHHHHHHHHHHHHHHHCCCEEEEEHHHHCCCCCCCCCEEEEEECCCCCEEEEEEECEEEE AIYNSPRQTVIAGPTEQIDELIDRVRAQNRFASRVNIEVAPHNPAMDALQPQMRSELADV EEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHC APRTPTIPILSTTYADLGSCPVFDAQHWATNMRNPVHFQQAIMTAGTDHRTFIEISAHPL CCCCCCCCEEECCHHCCCCCCCCCCHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEECCHH LTQAITDTLHGTRCISIGTLQRDADDTVTFHTNLNNVHTVHPPHTPHPAEPHVTIPSTPW HHHHHHHHHCCCEEEEEECCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCEEECCCCCH QHTRHWIPRKRSVNSIGLAPQVGTLLGQHTAVSGILPIHLWQARLAPQAKPYRGWHRVHG HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHCC VEVVPASIVLRTILCAAAELGYSTLFEIRFEQPIFANLPRLIQVVVDNQLISLASSPATE CEECHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCHHHHHCCCCCCC TPQHRWTRHVTAQLSSASARSAVPSDHPDQINGHLEVISDPIPDVASLLALCGVDGLPFE CCHHHHHHHHHHHHHHCHHHCCCCCCCCHHCCCEEEEECCCCHHHHHHHHHHCCCCCCCC WSVKSWAKKTQQSTSRTVEIEFPDTLPDGAIAPLLDAAILIPALADVTETQFYVPASIKQ CCHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCHHE VWLGDTATGPCGAVTLNRTACDDDGITVDVTVADGSGVPLALMRSLRYRALDLDNAQQDY EEECCCCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHH STVFVESHVDALTDARNFVHAIDWQPRTDLDCSNTPVASSGSVAVIGDARAGFGLLLKEA HEEEHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHC GYTLAAPADGVSEVRYVVYVADPHPATTAETDVDFAVRITAEISDLVRALAKREPGKPVA CCEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCEE LWIVTRGVYESVASSALRQSFLWGFGGVIAAEHPEMWGGLVDLAASALGADRDDILDQFG EEEEEHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHC PTLASLLQTPTRSIVVLRDGVVLAPTLVPIRSEPVRKSLQCKSDGAYLITGGMGALGLLM HHHHHHHCCCCCEEEEEECCEEEECEEECCCCCHHHHHHCCCCCCCEEEECCHHHHHHHH ADWLADRGARRLVLMGRTPLPPRRDWELDTLDAGLRQKIDAICALEMRGVTVEAVAVDVG HHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCEEEEEEEECC HHDDVQALLAKRDRDGAAPIRGIIHAAGVTNDQLVTNMTDDPVRQVMWPKIAGCQVLHEA CCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEECCCCHHHHHHHCCCHHHHHHHHHC FPPGSVDFFYLTSSAAGIFGIPGQGSYAAANSYLDALARTRRQQGCHTMSIDWVAWRGLG CCCCCEEEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECEEEECCCC FAANAQIVSDELQRMGSRDITPSEAFTAWEYVDAYDVAQAVVLPVPRSYGSAGSTAGDSY CCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCE LVPARNWSQMEAAEVRKELESGLRTIIAAELRVAEAELDTDRPFAELGLNSLMAMAIRRE EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH AEQFIGIELSAIMLFNHPTVALLAAYLTKVVAPQHDSQGDEMAALSASAGGVLDSLFDRI HHHHHCEEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHH ESTSTEAEGLV HCCCCCCCCCC >Mature Secondary Structure TASIGSEADLCHWLVNYLVTNIGCTPDEVDLNLSLTDLGMSSRDAVVLSGELTDLLGKT CCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCEEEEECCHHHHHCCC VSPIDFWEHPTINALAAYLIAPAPDPESESAPRRSVQGALEEPIAVIGMGCRFPGGISGP CCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCH EALWQFLCDRRSSIGQVPNERWELFDDGSPEVKALLARTTRWGSFLEDIDAFDSEFFEIS HHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEC PSEADKMDPQQRLLLEVAWEALEHAGISSNSLRRSQTGVFAGSCLSEYGAIASTDLSQVD CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHCCCCCCCCHHHCC GWSNTGGAMSIIANRLSYFLDLRGPSVAVDTACSSSLVAIHLACQSLRTADANLAIAAGV CCCCCCHHHHHHHHHHHHHEECCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEECCH NLLLSPAVFRGFDQVGALSPTGCCRAFDAAADGFVRGEGAGVVVLKRLTDAQRDGDRVLA HHHHCHHHHHCHHHHCCCCCCHHHHHHHHHCCCCEECCCCCEEEEEHHHHCCCCCCEEEE IIRGSAVNQDGRSNGLMAPNPAAQVAVLRTAYANAAMPPTAIDYVETHGTGTLLGDPIEA EEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHEEECCCCCCCCCCHHH RALGAVLGRGRAEDSPLLIGAVKTNLGHLEAAAGIAGFIKTVLAVQRGQIPPNQRFESPN HHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC LHIPFAELRMKVVDKHMEWPDTGHLRRAAVSSFGFGGTNAHVVIEQGPELTPVTECSSNT CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHCCCCCC AVSTLVVTGKTASRVAAMAGMLADWVEGPGAEVALADVAHTLNHHRSRHAKFGTVVARDR EEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH IQAVAGLRALAAGKQAPGVVGQQDGTPGSGTVFVYSGRGSQWAGMGRQLLADEPAFTAAV HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHCCHHHHCCCCHHHHHH AELEPVFVVHAGFSLHDVLANGKELVGIEQIQLGLIGMQLTLTELWRSYGVQPDLVIGHS HHCCEEEEEECCCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCC LGEVAAAVVAGALTAAEGLRVTATRSRLMAPLSGQGGMALLELDAVETEALIVDYSQVTL HHHHHHHHHHHHHHHHCCCEEEEEHHHHCCCCCCCCCEEEEEECCCCCEEEEEEECEEEE AIYNSPRQTVIAGPTEQIDELIDRVRAQNRFASRVNIEVAPHNPAMDALQPQMRSELADV EEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHC APRTPTIPILSTTYADLGSCPVFDAQHWATNMRNPVHFQQAIMTAGTDHRTFIEISAHPL CCCCCCCCEEECCHHCCCCCCCCCCHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEECCHH LTQAITDTLHGTRCISIGTLQRDADDTVTFHTNLNNVHTVHPPHTPHPAEPHVTIPSTPW HHHHHHHHHCCCEEEEEECCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCEEECCCCCH QHTRHWIPRKRSVNSIGLAPQVGTLLGQHTAVSGILPIHLWQARLAPQAKPYRGWHRVHG HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHCC VEVVPASIVLRTILCAAAELGYSTLFEIRFEQPIFANLPRLIQVVVDNQLISLASSPATE CEECHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCHHHHHCCCCCCC TPQHRWTRHVTAQLSSASARSAVPSDHPDQINGHLEVISDPIPDVASLLALCGVDGLPFE CCHHHHHHHHHHHHHHCHHHCCCCCCCCHHCCCEEEEECCCCHHHHHHHHHHCCCCCCCC WSVKSWAKKTQQSTSRTVEIEFPDTLPDGAIAPLLDAAILIPALADVTETQFYVPASIKQ CCHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCHHE VWLGDTATGPCGAVTLNRTACDDDGITVDVTVADGSGVPLALMRSLRYRALDLDNAQQDY EEECCCCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHH STVFVESHVDALTDARNFVHAIDWQPRTDLDCSNTPVASSGSVAVIGDARAGFGLLLKEA HEEEHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHC GYTLAAPADGVSEVRYVVYVADPHPATTAETDVDFAVRITAEISDLVRALAKREPGKPVA CCEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCEE LWIVTRGVYESVASSALRQSFLWGFGGVIAAEHPEMWGGLVDLAASALGADRDDILDQFG EEEEEHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHC PTLASLLQTPTRSIVVLRDGVVLAPTLVPIRSEPVRKSLQCKSDGAYLITGGMGALGLLM HHHHHHHCCCCCEEEEEECCEEEECEEECCCCCHHHHHHCCCCCCCEEEECCHHHHHHHH ADWLADRGARRLVLMGRTPLPPRRDWELDTLDAGLRQKIDAICALEMRGVTVEAVAVDVG HHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCEEEEEEEECC HHDDVQALLAKRDRDGAAPIRGIIHAAGVTNDQLVTNMTDDPVRQVMWPKIAGCQVLHEA CCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEECCCCHHHHHHHCCCHHHHHHHHHC FPPGSVDFFYLTSSAAGIFGIPGQGSYAAANSYLDALARTRRQQGCHTMSIDWVAWRGLG CCCCCEEEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECEEEECCCC FAANAQIVSDELQRMGSRDITPSEAFTAWEYVDAYDVAQAVVLPVPRSYGSAGSTAGDSY CCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCE LVPARNWSQMEAAEVRKELESGLRTIIAAELRVAEAELDTDRPFAELGLNSLMAMAIRRE EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH AEQFIGIELSAIMLFNHPTVALLAAYLTKVVAPQHDSQGDEMAALSASAGGVLDSLFDRI HHHHHCEEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHH ESTSTEAEGLV HCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: None [C]
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): 0.04 {acetyl-ACP}} 0.031 {acetyl-ACP}} 0.138 {cis-9-hexadecenoyl-ACP}} 0.017 {cis-9-hexadecenoyl-ACP}} 0.012 {cis-3-decenoyl-ACP}} [C]
Substrates: acetyl-ACP; malonyl-ACP; acyl-ACP [C]
Specific reaction: acetyl-ACP + malonyl-ACP = [acyl carrier protein] + acetoacetyl-ACP + CO2 acyl-ACP + malonyl-ACP = [acyl carrier protein] + beta-ketoacyl-ACP + CO2 [C]
General reaction: Acyl group transfer [C]
Inhibitor: Acetyl-CoA; Acyl-CoA; Iodoacetamide; N-Ethyl maleimide acyl -ACP-derivatives protect, malonyl-ACP-decarboxylation, Cerulenin [C]
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9634230; 12218036 [H]