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The map label for this gene is tlyA [H]

Identifier: 221230182

GI number: 221230182

Start: 1618042

End: 1618851

Strand: Direct

Name: tlyA [H]

Synonym: MLBr_01358

Alternate gene names: 221230182

Gene position: 1618042-1618851 (Clockwise)

Preceding gene: 221230181

Following gene: 221230183

Centisome position: 49.51

GC content: 63.58

Gene sequence:

>810_bases
GTGGCCCGACGTGTCCGCGTTGATGTTGAGCTGGTCCGACGTGGCCTTGCGCGGTCCCGTCAACAGGCCGCGAAATTGAT
AAGCGCCGGTAAGGTTAGCATCGACGGTTTGCCGGCGGTCAAGCCGAGCACCGCCGTGGCCATAACCACGGTCTTGACCG
TCGCGGACGATGGTGAGCGTAGTTGGGTGTCGCGCGGAGCGCACAAACTTATGGGTGCGCTTGACACTTTCGGGATCCCG
GTCGCGGGGCGTTGCTGCCTTGACGCTGGCGCGTCCACGGGTGGATTTACTGAAGTTCTGCTGGATCGCGGGGCCGCCGA
GGTGGTAGCTGTGGATGTGGGGTACGGTCAGCTGGCCTGGTCGGTGCGCTGCGATCCGCGCGTGATCGTTGTCGAACGGA
CCAATGTGCACGACTTGTCACCCGAGCTGATCGGCGGGCCGGTTGATTTGGTGGTGGCTGACCTGTCGTTCATTTCATTA
GCCACCGTCTTGTCGGCGCTGGCTGGCTGCGCATTACCGAGCGCGGATATCGTTCCCATGGTGAAGCCGCAGTTTGAGGT
GGGCAAGGGTCAGGTGGGTCCCGGCGGGGTGGTTCGCGACCTGCGGCTTCGAGCAGATTCGGTTCTGGCCGTCGCGCGTC
GTGCGACAGAGCTCGGATGGCGCACCATGGATGTGACTGCCAGCTCGCTACCGGGTCTGTCAGGCAACGTCGAATACTTC
CTGTGGCTACGCGCTCAGACCGATCTGGAGCTCTCGACCGATGGGCTGGAGGCAGCCGTGCAACGTGCCATCGCAGAAGG
CCCGCAGTGA

Upstream 100 bases:

>100_bases
CTATCTCTTGCCCAGCTCGAAGAGGTAGCGCTCCGTTTTTCCGAGGTGCATTCCGTGCTGTTGCAGGCTCTAGAGTCAGC
GGAGAAGGGTTGACTGCATC

Downstream 100 bases:

>100_bases
CTCCTCGCAAGGCGGCGCAACGGACTGTGTTGCTGGTCGTCCACACCGGACGTGACGAAGCAACCGAGACGGCTCGTCGT
GTAAAGAAAATTGTGGGCGA

Product: cytotoxin/hemolysin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MARRVRVDVELVRRGLARSRQQAAKLISAGKVSIDGLPAVKPSTAVAITTVLTVADDGERSWVSRGAHKLMGALDTFGIP
VAGRCCLDAGASTGGFTEVLLDRGAAEVVAVDVGYGQLAWSVRCDPRVIVVERTNVHDLSPELIGGPVDLVVADLSFISL
ATVLSALAGCALPSADIVPMVKPQFEVGKGQVGPGGVVRDLRLRADSVLAVARRATELGWRTMDVTASSLPGLSGNVEYF
LWLRAQTDLELSTDGLEAAVQRAIAEGPQ

Sequences:

>Translated_269_residues
MARRVRVDVELVRRGLARSRQQAAKLISAGKVSIDGLPAVKPSTAVAITTVLTVADDGERSWVSRGAHKLMGALDTFGIP
VAGRCCLDAGASTGGFTEVLLDRGAAEVVAVDVGYGQLAWSVRCDPRVIVVERTNVHDLSPELIGGPVDLVVADLSFISL
ATVLSALAGCALPSADIVPMVKPQFEVGKGQVGPGGVVRDLRLRADSVLAVARRATELGWRTMDVTASSLPGLSGNVEYF
LWLRAQTDLELSTDGLEAAVQRAIAEGPQ
>Mature_268_residues
ARRVRVDVELVRRGLARSRQQAAKLISAGKVSIDGLPAVKPSTAVAITTVLTVADDGERSWVSRGAHKLMGALDTFGIPV
AGRCCLDAGASTGGFTEVLLDRGAAEVVAVDVGYGQLAWSVRCDPRVIVVERTNVHDLSPELIGGPVDLVVADLSFISLA
TVLSALAGCALPSADIVPMVKPQFEVGKGQVGPGGVVRDLRLRADSVLAVARRATELGWRTMDVTASSLPGLSGNVEYFL
WLRAQTDLELSTDGLEAAVQRAIAEGPQ

Specific function: Unknown

COG id: COG1189

COG function: function code J; Predicted rRNA methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004538
- InterPro:   IPR002877
- InterPro:   IPR002942 [H]

Pfam domain/function: PF01728 FtsJ; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 28204; Mature: 28073

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS50889 S4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARRVRVDVELVRRGLARSRQQAAKLISAGKVSIDGLPAVKPSTAVAITTVLTVADDGER
CCCEEEECHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCEEEEEEEEECCCCCH
SWVSRGAHKLMGALDTFGIPVAGRCCLDAGASTGGFTEVLLDRGAAEVVAVDVGYGQLAW
HHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCHHHHHHCCCCCEEEEEECCCCEEEE
SVRCDPRVIVVERTNVHDLSPELIGGPVDLVVADLSFISLATVLSALAGCALPSADIVPM
EEECCCEEEEEEECCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VKPQFEVGKGQVGPGGVVRDLRLRADSVLAVARRATELGWRTMDVTASSLPGLSGNVEYF
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHCCCCCCCEEEE
LWLRAQTDLELSTDGLEAAVQRAIAEGPQ
EEEEECCCCEECCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ARRVRVDVELVRRGLARSRQQAAKLISAGKVSIDGLPAVKPSTAVAITTVLTVADDGER
CCEEEECHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCEEEEEEEEECCCCCH
SWVSRGAHKLMGALDTFGIPVAGRCCLDAGASTGGFTEVLLDRGAAEVVAVDVGYGQLAW
HHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCHHHHHHCCCCCEEEEEECCCCEEEE
SVRCDPRVIVVERTNVHDLSPELIGGPVDLVVADLSFISLATVLSALAGCALPSADIVPM
EEECCCEEEEEEECCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VKPQFEVGKGQVGPGGVVRDLRLRADSVLAVARRATELGWRTMDVTASSLPGLSGNVEYF
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHCCCCCCCEEEE
LWLRAQTDLELSTDGLEAAVQRAIAEGPQ
EEEEECCCCEECCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 2507400 [H]