Click here to switch to the map view.

The map label for this gene is uppP

Identifier: 221230145

GI number: 221230145

Start: 1546139

End: 1546987

Strand: Direct

Name: uppP

Synonym: MLBr_01297

Alternate gene names: 221230145

Gene position: 1546139-1546987 (Clockwise)

Preceding gene: 221230144

Following gene: 221230146

Centisome position: 47.31

GC content: 59.84

Gene sequence:

>849_bases
GTGACTGCGGTTTCGGCGATGTCCTGGTGGCAAGTCATCGTTTTGGCCGTGGTGCAAGGTCTCACGGAGTTCCTGCCGGT
GTCATCCTCGGGTCACCTGGCGATTGTGTCGCGGATCTTGTTCACTGGCGATGCTGGCGCCTCATTCACCGCGGTCAGCC
AACTGGGCACTGAGGTCGCGGTGCTGGTGTACTTCGGACGCGACATCGTACGCATTCTCCATGCCTGGTGTAGAGGCCTG
ACCGTCACGTTGCACCGCACCGCGGACTATTGGTTGGGCTGGTATGTGATCATCGGGACCATCCCAATCTGCATCCTGGG
CCTGGTGTGCAAGGACGAGATCCGCTCGGGAATTCGTCCTCTGTGGGTCGTAGCGACCGCGTTGGTGGCGTTTTCGGGGG
TAATCGCCTTCGCTGAGTATGTCGGGCGTCAGAATCGTTGTATCGAGCAGCTGAACTGGCGTGACGCTCTGGTGGTAGGA
GTGGCCCAAACGCTTGCGTTGATTCCTGGTGTCTCACGATCCGGCTCGACTATCAGCGCTGGGCTGTTTCTCGGACTAGA
TCGTGAATTGGCCGCCCGATTCGGCTTCCTCCTGGCCATACCCGCTGTGTTCGCGTCCGGGTTGTTCTCGATACCGGACG
CCTTCCATCCTATCACTGAGGGTATGAGTGCCACCGGCGCGCAGCTGCTGGTGGCCACTGTGATCGCATTTGTCGTCGGT
TTGGTTGCGGTGTCCTGGTTGCTGCGGTTTCTGGTGCAGCACAACCTGTACTGGTTCGTCGGCTACCGGATAGTCGTCGG
CGTGGGTGTACTGATCCTGCTGGCGGTCAAGACGGTAGCTGCGACATGA

Upstream 100 bases:

>100_bases
CGCAGCCTGGCTGCGGCGGTGCGAGATTTGGTCGCACGCACGTTAACGGTCTCAGGTTAGTCGCATCAGGTACCGGCTGC
CACCAGGTACGGTCGTCGTC

Downstream 100 bases:

>100_bases
CGGTCATTTTGTTGCGGCACGGGCGGTCCACATCGAATACCGCAGGTGTTTTAGCTGGTCGGGCCGATGGGGTCGACCTC
GACGACAGGGGCCGCGAGCA

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MTAVSAMSWWQVIVLAVVQGLTEFLPVSSSGHLAIVSRILFTGDAGASFTAVSQLGTEVAVLVYFGRDIVRILHAWCRGL
TVTLHRTADYWLGWYVIIGTIPICILGLVCKDEIRSGIRPLWVVATALVAFSGVIAFAEYVGRQNRCIEQLNWRDALVVG
VAQTLALIPGVSRSGSTISAGLFLGLDRELAARFGFLLAIPAVFASGLFSIPDAFHPITEGMSATGAQLLVATVIAFVVG
LVAVSWLLRFLVQHNLYWFVGYRIVVGVGVLILLAVKTVAAT

Sequences:

>Translated_282_residues
MTAVSAMSWWQVIVLAVVQGLTEFLPVSSSGHLAIVSRILFTGDAGASFTAVSQLGTEVAVLVYFGRDIVRILHAWCRGL
TVTLHRTADYWLGWYVIIGTIPICILGLVCKDEIRSGIRPLWVVATALVAFSGVIAFAEYVGRQNRCIEQLNWRDALVVG
VAQTLALIPGVSRSGSTISAGLFLGLDRELAARFGFLLAIPAVFASGLFSIPDAFHPITEGMSATGAQLLVATVIAFVVG
LVAVSWLLRFLVQHNLYWFVGYRIVVGVGVLILLAVKTVAAT
>Mature_281_residues
TAVSAMSWWQVIVLAVVQGLTEFLPVSSSGHLAIVSRILFTGDAGASFTAVSQLGTEVAVLVYFGRDIVRILHAWCRGLT
VTLHRTADYWLGWYVIIGTIPICILGLVCKDEIRSGIRPLWVVATALVAFSGVIAFAEYVGRQNRCIEQLNWRDALVVGV
AQTLALIPGVSRSGSTISAGLFLGLDRELAARFGFLLAIPAVFASGLFSIPDAFHPITEGMSATGAQLLVATVIAFVVGL
VAVSWLLRFLVQHNLYWFVGYRIVVGVGVLILLAVKTVAAT

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=263, Percent_Identity=34.6007604562738, Blast_Score=127, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_MYCLB (B8ZRD4)

Other databases:

- EMBL:   FM211192
- RefSeq:   YP_002503561.1
- EnsemblBacteria:   EBMYCT00000085167
- GeneID:   7326451
- GenomeReviews:   FM211192_GR
- GeneTree:   EBGT00050000016010
- HOGENOM:   HBG391969
- OMA:   YEASSIR
- ProtClustDB:   PRK00281
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30273; Mature: 30142

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x29cb31a0)-; HASH(0x2a0f0810)-; HASH(0x2a0ef9ac)-; HASH(0x2a0f21fc)-; HASH(0x29f99a48)-; HASH(0x2a0eef68)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
TAVSAMSWWQVIVLAVVQGLTEFLPVSSSGHLAIVSRILFTGDAGASFTAVSQLGTEVA
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCHHHH
VLVYFGRDIVRILHAWCRGLTVTLHRTADYWLGWYVIIGTIPICILGLVCKDEIRSGIRP
HHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
LWVVATALVAFSGVIAFAEYVGRQNRCIEQLNWRDALVVGVAQTLALIPGVSRSGSTISA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCEEH
GLFLGLDRELAARFGFLLAIPAVFASGLFSIPDAFHPITEGMSATGAQLLVATVIAFVVG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LVAVSWLLRFLVQHNLYWFVGYRIVVGVGVLILLAVKTVAAT
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA