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The map label for this gene is 221230066

Identifier: 221230066

GI number: 221230066

Start: 1365591

End: 1366679

Strand: Direct

Name: 221230066

Synonym: MLBr_01167

Alternate gene names: NA

Gene position: 1365591-1366679 (Clockwise)

Preceding gene: 221230065

Following gene: 221230067

Centisome position: 41.79

GC content: 64.65

Gene sequence:

>1089_bases
ATGATCTTGATGGCAGCGCCGATGAACTCCATAACCGACATTTCGGGTATCCAGGTTGGCCACTACCACAGGCTTGATCC
TGATGCGTCCCTTGGTGCGGGTTGGGCGTGTGGTGTGACTGTTGTGCTGACACCGCCTGGGACGGTTGGCGCGGTCGATT
GCCGGGGTGGGGTGCCAGGCACCCGGGAGACCGATTTGCTTGATCCAGCCAACAGTGTGCGGTTCGTTGATGCGGTGTTG
CTCGCCGGCGGTAGCGCCTACGGTCTGGCAGCCGCCGATGGCGTCATGCGCTGGCTGGAGGAACACGAGCGCGGCGTGGT
GATGCTCGGCGGAGTGGTGCCCATCGTGCCGGGTGCGGTGATTTTCGATTTGTCAGTCGGTGACTTTCATTGCCGACCGA
CAGCGGAATTCGGCTATTTGGCTTGTCAAGCCGCTTACGATGCCGCTGTTGGTGGTCAAGATGCCACCGTGGCTGTCGGG
ACGGTGGGTGCCGGGGTGGGGGCCCGCGCTGGCGTGCTTAAGGGTGGTGTCGGCACCGCGTCGATCACACTGGAGTCGGG
GCCGACGGTGGGCGCGGTGGTCGTGGTGAACTCCGTGGGCGATGTCGTCGACCGCGCCACTGGTCTGCCCTGGATGACAG
ATCTGATCGACGAGTTCGCTCTGCGACCACCCTCGCCCGAGCAGATCGCCGGGTTTGCACAGCTAAAGTCCCCGTTGAGC
GCGCTGAACACGACGATCGGCGTGGTAGCGACCGATGCCACGCTGAGCCCGGCGGCGTGCCAGCGTGTCGCAATGGCCGC
TCAGGACGGCCTGGCCCGAACTATCCGTCCAGCGCACACTGCGCTGGACGGTGACACGGTGTTCGCACTGGCCACCGGAG
CGGTCGAAGCCACAGCGACGGCTGATGTACCCGTCGCGATGTCGCCGGAGACGGGCCTGATCACTGAGGTCGGTGCGGCT
GCGGACGACTGTTTGGCTCGTGCAGTGCTGGTTGCGGTGCTGGCTGCCGAGTCGGTCGCTGGAATACCGACTTACTGCGG
CATGTTTCCTGGAGCGTTCGGGACCACAATCGGAGGGGGCAACCGTTGA

Upstream 100 bases:

>100_bases
AACGGGTGCCGGCCGGTCATCCACTATCCGTGCACTTCGACGTCTACCAGTGGCTGACGGTGTTGCAGGAATACTTGGTT
TTGGCGCTGATGGCTACCTG

Downstream 100 bases:

>100_bases
CGTGGTGGTGATTCGTGCTGACTGGTGGAGGCGATAGTGTCCCACGCACGTCGCGACCACCCTGACGAAGCGTGTGGGGT
GCTGGTCGGTCTCGAGGGTT

Product: putative hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MILMAAPMNSITDISGIQVGHYHRLDPDASLGAGWACGVTVVLTPPGTVGAVDCRGGVPGTRETDLLDPANSVRFVDAVL
LAGGSAYGLAAADGVMRWLEEHERGVVMLGGVVPIVPGAVIFDLSVGDFHCRPTAEFGYLACQAAYDAAVGGQDATVAVG
TVGAGVGARAGVLKGGVGTASITLESGPTVGAVVVVNSVGDVVDRATGLPWMTDLIDEFALRPPSPEQIAGFAQLKSPLS
ALNTTIGVVATDATLSPAACQRVAMAAQDGLARTIRPAHTALDGDTVFALATGAVEATATADVPVAMSPETGLITEVGAA
ADDCLARAVLVAVLAAESVAGIPTYCGMFPGAFGTTIGGGNR

Sequences:

>Translated_362_residues
MILMAAPMNSITDISGIQVGHYHRLDPDASLGAGWACGVTVVLTPPGTVGAVDCRGGVPGTRETDLLDPANSVRFVDAVL
LAGGSAYGLAAADGVMRWLEEHERGVVMLGGVVPIVPGAVIFDLSVGDFHCRPTAEFGYLACQAAYDAAVGGQDATVAVG
TVGAGVGARAGVLKGGVGTASITLESGPTVGAVVVVNSVGDVVDRATGLPWMTDLIDEFALRPPSPEQIAGFAQLKSPLS
ALNTTIGVVATDATLSPAACQRVAMAAQDGLARTIRPAHTALDGDTVFALATGAVEATATADVPVAMSPETGLITEVGAA
ADDCLARAVLVAVLAAESVAGIPTYCGMFPGAFGTTIGGGNR
>Mature_362_residues
MILMAAPMNSITDISGIQVGHYHRLDPDASLGAGWACGVTVVLTPPGTVGAVDCRGGVPGTRETDLLDPANSVRFVDAVL
LAGGSAYGLAAADGVMRWLEEHERGVVMLGGVVPIVPGAVIFDLSVGDFHCRPTAEFGYLACQAAYDAAVGGQDATVAVG
TVGAGVGARAGVLKGGVGTASITLESGPTVGAVVVVNSVGDVVDRATGLPWMTDLIDEFALRPPSPEQIAGFAQLKSPLS
ALNTTIGVVATDATLSPAACQRVAMAAQDGLARTIRPAHTALDGDTVFALATGAVEATATADVPVAMSPETGLITEVGAA
ADDCLARAVLVAVLAAESVAGIPTYCGMFPGAFGTTIGGGNR

Specific function: Unknown

COG id: COG3191

COG function: function code EQ; L-aminopeptidase/D-esterase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis Rv1333

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1167_MYCLE (P53425)

Other databases:

- EMBL:   U00014
- EMBL:   AL583921
- PIR:   S72794
- RefSeq:   NP_301852.1
- ProteinModelPortal:   P53425
- SMR:   P53425
- EnsemblBacteria:   EBMYCT00000029014
- GeneID:   910265
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML1167
- NMPDR:   fig|272631.1.peg.724
- Leproma:   ML1167
- GeneTree:   EBGT00050000016187
- HOGENOM:   HBG759105
- OMA:   FDLLNGG
- ProtClustDB:   CLSK791103
- BioCyc:   MLEP272631:ML1167-MONOMER
- InterPro:   IPR016117
- InterPro:   IPR005321
- Gene3D:   G3DSA:3.60.70.12

Pfam domain/function: PF03576 Peptidase_S58; SSF56266 Pept_S58_DmpA/Arg_biosyn_ArgJ

EC number: NA

Molecular weight: Translated: 36105; Mature: 36105

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x29de88e4)-; HASH(0x29d2034c)-; HASH(0x29e48584)-; HASH(0x297c8c34)-; HASH(0x29ae619c)-; HASH(0x29c7aa58)-; HASH(0x29a51c54)-;

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILMAAPMNSITDISGIQVGHYHRLDPDASLGAGWACGVTVVLTPPGTVGAVDCRGGVPG
CEEEECCCCCCCCCCCEEECCEEECCCCCCCCCCEECCEEEEECCCCCEEEEECCCCCCC
TRETDLLDPANSVRFVDAVLLAGGSAYGLAAADGVMRWLEEHERGVVMLGGVVPIVPGAV
CCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCHHHCCCEE
IFDLSVGDFHCRPTAEFGYLACQAAYDAAVGGQDATVAVGTVGAGVGARAGVLKGGVGTA
EEEECCCCEECCCCCCCCCEEHHHHHHHHCCCCCCEEEEEECCCCCCCCCCEEECCCCEE
SITLESGPTVGAVVVVNSVGDVVDRATGLPWMTDLIDEFALRPPSPEQIAGFAQLKSPLS
EEEECCCCCEEEEEEECCHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ALNTTIGVVATDATLSPAACQRVAMAAQDGLARTIRPAHTALDGDTVFALATGAVEATAT
HHHCEEEEEEECCCCCHHHHHHHHHHHHCCHHHHCCHHHHHCCCCEEEEEEECCEEEEEC
ADVPVAMSPETGLITEVGAAADDCLARAVLVAVLAAESVAGIPTYCGMFPGAFGTTIGGG
CCCCEEECCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCC
NR
CH
>Mature Secondary Structure
MILMAAPMNSITDISGIQVGHYHRLDPDASLGAGWACGVTVVLTPPGTVGAVDCRGGVPG
CEEEECCCCCCCCCCCEEECCEEECCCCCCCCCCEECCEEEEECCCCCEEEEECCCCCCC
TRETDLLDPANSVRFVDAVLLAGGSAYGLAAADGVMRWLEEHERGVVMLGGVVPIVPGAV
CCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCHHHCCCEE
IFDLSVGDFHCRPTAEFGYLACQAAYDAAVGGQDATVAVGTVGAGVGARAGVLKGGVGTA
EEEECCCCEECCCCCCCCCEEHHHHHHHHCCCCCCEEEEEECCCCCCCCCCEEECCCCEE
SITLESGPTVGAVVVVNSVGDVVDRATGLPWMTDLIDEFALRPPSPEQIAGFAQLKSPLS
EEEECCCCCEEEEEEECCHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ALNTTIGVVATDATLSPAACQRVAMAAQDGLARTIRPAHTALDGDTVFALATGAVEATAT
HHHCEEEEEEECCCCCHHHHHHHHHHHHCCHHHHCCHHHHHCCCCEEEEEEECCEEEEEC
ADVPVAMSPETGLITEVGAAADDCLARAVLVAVLAAESVAGIPTYCGMFPGAFGTTIGGG
CCCCEEECCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCC
NR
CH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11234002