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The map label for this gene is murA [H]

Identifier: 221230058

GI number: 221230058

Start: 1339620

End: 1340876

Strand: Direct

Name: murA [H]

Synonym: MLBr_01150

Alternate gene names: 221230058

Gene position: 1339620-1340876 (Clockwise)

Preceding gene: 221230055

Following gene: 221230060

Centisome position: 40.99

GC content: 59.98

Gene sequence:

>1257_bases
GTGGCAGAGCGATTCGTGGTGACCGGCGGCAACCGGTTGTCAGGCGAAGTCACCGTCGGAGGTGCCAAGAACAGCGTCCT
CAAGCTTATGGCCGCGACTTTGTTGGCCGAAGGCACCAGCACGATCACCAATTGCCCCGACATCCTCGATGTGCCACTGA
TGGCGGAGGTGCTGCGGGGTCTAGGCGCCACTGTCGAACTCTATGGTGACGTTGCCAGAATCACTTCGCCTGACGAACCG
AAGTACGATGCTGACTTCGCTGCCGTGCGGCAGTTCCGGGCTTCGGTCTGTGTGCTGGGGCCGCTGGTCGGCCGGTGCAA
ACAAGCCAGGGTCGCGCTTCCGGGCGGTGACGCTATCGGATCGCGTCCGCTAGATATGCATCAGGCTGGTCTACGGCAGC
TGGGAGCACGCTGCAATATCGAGCACGGATGCGTGGTGGCTTCCGCAGAAACATTGCGCGGCGCTGAGATTCAGTTGGAG
TTTCCTTCAGTGGGCGCTACCGAGAACATCCTGATGGCAGCTGTTGTGGCTGAGGGTGTGACCACAATTCACAATGCAGC
CCGGGAACCCGACGTGGTTGACCTGTGCACGATGTTGAACCAGATGGGTGCACAGGTCGAAGGCGTGGGTTCGCCGACCA
TGACGATCACCGGCGTCCCGCGGCTCTACCCGACCGAACACCGCGTCATCGGAGACCGGATTGTAGCCGCTACGTGGGGC
ATTGCTGCTGCCATGACCCGCGGCGACATAGCTGTGACTGGCGTTGATCCTGCTCACCTTCAGCTAGTGTTGCATAAGTT
GCATGACGCGGGTGCTACCGTAACCCAGACGGACGACAGCTTTCGCGTGGCCCAGTACGAGCGCCCGAAGGCCGTCAATG
TGGCGACCTTGCCATTTCCCGGTTTTCCGACCGATTTGCAGCCAATGGCGATCGCTTTGACTTCGATCGCTGATGGCACG
TCGATGATTACGGAGAATGTGTTTGAGGCACGATTCCGCTTTGTCGAAGAGATGATCCGGCTGGGTGCCGATGCCCGCAC
GGATGGGCACCATGCCGTTGTGCGGGGTCTTCCACAACTCTCGAGCGCGCCGGTCTGGTGTTCGGATATCCGTGCTGGTG
CCGGTTTGGTACTCGCGGGACTTGTCGCTGATGGAGACACCGAGGTCTACGACGTTTTCCACATCGATCGCGGGTATCCA
TTGTTCGTGGAGAACCTGGCGAATTTAGGAGCCGAGATCGAGCGAGTATGCTTGTAG

Upstream 100 bases:

>100_bases
AAGTCAACTAGCTTGGCTTCTCCTCACTCCGCTCAGCGGAGTGAGGAGAAGCCAAGCTAGTTGACTGACAAGCCGATACC
GCTTCACTAGACTGACCCGG

Downstream 100 bases:

>100_bases
GTACTGCTCGTATAGTACCGCTGACACTGTCACCAGGCATTAAGATGTTATAGTCAACCCGGGACTTGACTCCTCTGCTG
GATCTGTATTAATCTGGCTG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MAERFVVTGGNRLSGEVTVGGAKNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELYGDVARITSPDEP
KYDADFAAVRQFRASVCVLGPLVGRCKQARVALPGGDAIGSRPLDMHQAGLRQLGARCNIEHGCVVASAETLRGAEIQLE
FPSVGATENILMAAVVAEGVTTIHNAAREPDVVDLCTMLNQMGAQVEGVGSPTMTITGVPRLYPTEHRVIGDRIVAATWG
IAAAMTRGDIAVTGVDPAHLQLVLHKLHDAGATVTQTDDSFRVAQYERPKAVNVATLPFPGFPTDLQPMAIALTSIADGT
SMITENVFEARFRFVEEMIRLGADARTDGHHAVVRGLPQLSSAPVWCSDIRAGAGLVLAGLVADGDTEVYDVFHIDRGYP
LFVENLANLGAEIERVCL

Sequences:

>Translated_418_residues
MAERFVVTGGNRLSGEVTVGGAKNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELYGDVARITSPDEP
KYDADFAAVRQFRASVCVLGPLVGRCKQARVALPGGDAIGSRPLDMHQAGLRQLGARCNIEHGCVVASAETLRGAEIQLE
FPSVGATENILMAAVVAEGVTTIHNAAREPDVVDLCTMLNQMGAQVEGVGSPTMTITGVPRLYPTEHRVIGDRIVAATWG
IAAAMTRGDIAVTGVDPAHLQLVLHKLHDAGATVTQTDDSFRVAQYERPKAVNVATLPFPGFPTDLQPMAIALTSIADGT
SMITENVFEARFRFVEEMIRLGADARTDGHHAVVRGLPQLSSAPVWCSDIRAGAGLVLAGLVADGDTEVYDVFHIDRGYP
LFVENLANLGAEIERVCL
>Mature_417_residues
AERFVVTGGNRLSGEVTVGGAKNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELYGDVARITSPDEPK
YDADFAAVRQFRASVCVLGPLVGRCKQARVALPGGDAIGSRPLDMHQAGLRQLGARCNIEHGCVVASAETLRGAEIQLEF
PSVGATENILMAAVVAEGVTTIHNAAREPDVVDLCTMLNQMGAQVEGVGSPTMTITGVPRLYPTEHRVIGDRIVAATWGI
AAAMTRGDIAVTGVDPAHLQLVLHKLHDAGATVTQTDDSFRVAQYERPKAVNVATLPFPGFPTDLQPMAIALTSIADGTS
MITENVFEARFRFVEEMIRLGADARTDGHHAVVRGLPQLSSAPVWCSDIRAGAGLVLAGLVADGDTEVYDVFHIDRGYPL
FVENLANLGAEIERVCL

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=416, Percent_Identity=45.6730769230769, Blast_Score=325, Evalue=3e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 44227; Mature: 44096

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERFVVTGGNRLSGEVTVGGAKNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRG
CCCEEEEECCCEECCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHCHHHHHHHHHH
LGATVELYGDVARITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCKQARVALPGGDAIG
CCCEEEECCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCC
SRPLDMHQAGLRQLGARCNIEHGCVVASAETLRGAEIQLEFPSVGATENILMAAVVAEGV
CCCCHHHHHHHHHHCCCCCCCCCEEEEEHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHH
TTIHNAAREPDVVDLCTMLNQMGAQVEGVGSPTMTITGVPRLYPTEHRVIGDRIVAATWG
HHHHHHCCCCCHHHHHHHHHHHCCEEECCCCCEEEEECCCCCCCCCHHHHHCCHHHHHHH
IAAAMTRGDIAVTGVDPAHLQLVLHKLHDAGATVTQTDDSFRVAQYERPKAVNVATLPFP
HHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCCCEEEEECCCC
GFPTDLQPMAIALTSIADGTSMITENVFEARFRFVEEMIRLGADARTDGHHAVVRGLPQL
CCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCC
SSAPVWCSDIRAGAGLVLAGLVADGDTEVYDVFHIDRGYPLFVENLANLGAEIERVCL
CCCCCCHHHHCCCCCEEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHCHHHHHHCC
>Mature Secondary Structure 
AERFVVTGGNRLSGEVTVGGAKNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRG
CCEEEEECCCEECCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHCHHHHHHHHHH
LGATVELYGDVARITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCKQARVALPGGDAIG
CCCEEEECCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCC
SRPLDMHQAGLRQLGARCNIEHGCVVASAETLRGAEIQLEFPSVGATENILMAAVVAEGV
CCCCHHHHHHHHHHCCCCCCCCCEEEEEHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHH
TTIHNAAREPDVVDLCTMLNQMGAQVEGVGSPTMTITGVPRLYPTEHRVIGDRIVAATWG
HHHHHHCCCCCHHHHHHHHHHHCCEEECCCCCEEEEECCCCCCCCCHHHHHCCHHHHHHH
IAAAMTRGDIAVTGVDPAHLQLVLHKLHDAGATVTQTDDSFRVAQYERPKAVNVATLPFP
HHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCCCEEEEECCCC
GFPTDLQPMAIALTSIADGTSMITENVFEARFRFVEEMIRLGADARTDGHHAVVRGLPQL
CCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCC
SSAPVWCSDIRAGAGLVLAGLVADGDTEVYDVFHIDRGYPLFVENLANLGAEIERVCL
CCCCCCHHHHCCCCCEEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]