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The map label for this gene is suhB

Identifier: 221229971

GI number: 221229971

Start: 1191883

End: 1192758

Strand: Direct

Name: suhB

Synonym: MLBr_01024

Alternate gene names: 221229971

Gene position: 1191883-1192758 (Clockwise)

Preceding gene: 221229966

Following gene: 221229973

Centisome position: 36.47

GC content: 64.73

Gene sequence:

>876_bases
GTGACAGTACCTGACAACGATCCCGAGCAGCTGCGCTGCGTAGCCGAATCACTGGCCACTGAGGCCGCCGCGTTCGTGCG
ATGTCGCCGAGCTGAGGTGTTTGGTACTGACCTGGGCGCCGCAGGCGGCGGCGCGGTACGGGCGAAGAGTACCCCGACCG
ATCCGGTGACTGTCGTTGACACCGAGACAGAACGCTTGTTGCGTGATCGGCTCGCTCAACTACGGCCCGGTGACTCGATC
CTTGGGGAGGAGGGGGGTGGGCCCGCCGATCTGACCGCCACGCCTGCAGACACGGTAACCTGGGTGCTTGACCCCATCGA
TGGCACGGTGAACTTTGTCTACGGCATCCCGGCTTACGCGGTGTCGGTCGCAGCTCAGGTTGATGGCGTGTCAGTGGCCG
GCGCGGTTGCTGAAGTTGTTGCCGGTCGGGTGCACTCGGCGGCGAGCGGCCTCGGCGCGCATGTCACCGACGAGTATGGT
GTACAGGTACTGAGATGCAGCGCAGTCGATGACTTGTCGATGGCGCTGCTAGGTACTGGCTTTGCCTATTCGGTAGTGCG
CCGCGCCGCCCAGGCGGCGCTGTTGGCCCAGATGCTGCCGGTGGTACGTGATGTACGTCGCATCGGTTCGGCCGCGTTAG
ACCTTTGCATGGTTGCGGCGGGCCAGTTGGATGCTTATTACGAGCATGAGGTGCAGGTGTGGGATTGCGCGGCTGGCGCG
TTGATCGCGGCGGAAGCGGGGGCCTGTGTGCAGTTGCCTAAGCGGAACGGGCCCGTGGGCGGTGCCGGATTGGTGGTAGC
TGCCGCGCCTGGAATCGCCGACGCATTGTTGGCTGCCTTGCAGCGATTCAACGGCCTGGCGCCGATCCTGGACTAA

Upstream 100 bases:

>100_bases
GCAATCTCCTTGGCGAGACTTGGTTGTTCGCTTACTTTAGCCTGGCGATGATGCGGGCTGACTGTCTGGCATCTGCCGGC
GACTGTGATGCGATAGGCCA

Downstream 100 bases:

>100_bases
GGATCAGCAGCTGTTGGCGTGGATCTTTTGCAGCAGTGCAGGATCTGACGGCTCGGTGGCGCCGGGACGCAGGCTGGCCA
GCACAGCGTCGATGTCGTCG

Product: putative inositol monophosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MTVPDNDPEQLRCVAESLATEAAAFVRCRRAEVFGTDLGAAGGGAVRAKSTPTDPVTVVDTETERLLRDRLAQLRPGDSI
LGEEGGGPADLTATPADTVTWVLDPIDGTVNFVYGIPAYAVSVAAQVDGVSVAGAVAEVVAGRVHSAASGLGAHVTDEYG
VQVLRCSAVDDLSMALLGTGFAYSVVRRAAQAALLAQMLPVVRDVRRIGSAALDLCMVAAGQLDAYYEHEVQVWDCAAGA
LIAAEAGACVQLPKRNGPVGGAGLVVAAAPGIADALLAALQRFNGLAPILD

Sequences:

>Translated_291_residues
MTVPDNDPEQLRCVAESLATEAAAFVRCRRAEVFGTDLGAAGGGAVRAKSTPTDPVTVVDTETERLLRDRLAQLRPGDSI
LGEEGGGPADLTATPADTVTWVLDPIDGTVNFVYGIPAYAVSVAAQVDGVSVAGAVAEVVAGRVHSAASGLGAHVTDEYG
VQVLRCSAVDDLSMALLGTGFAYSVVRRAAQAALLAQMLPVVRDVRRIGSAALDLCMVAAGQLDAYYEHEVQVWDCAAGA
LIAAEAGACVQLPKRNGPVGGAGLVVAAAPGIADALLAALQRFNGLAPILD
>Mature_290_residues
TVPDNDPEQLRCVAESLATEAAAFVRCRRAEVFGTDLGAAGGGAVRAKSTPTDPVTVVDTETERLLRDRLAQLRPGDSIL
GEEGGGPADLTATPADTVTWVLDPIDGTVNFVYGIPAYAVSVAAQVDGVSVAGAVAEVVAGRVHSAASGLGAHVTDEYGV
QVLRCSAVDDLSMALLGTGFAYSVVRRAAQAALLAQMLPVVRDVRRIGSAALDLCMVAAGQLDAYYEHEVQVWDCAAGAL
IAAEAGACVQLPKRNGPVGGAGLVVAAAPGIADALLAALQRFNGLAPILD

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family

Homologues:

Organism=Homo sapiens, GI5031789, Length=208, Percent_Identity=35.0961538461538, Blast_Score=121, Evalue=9e-28,
Organism=Homo sapiens, GI221625487, Length=208, Percent_Identity=35.0961538461538, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI7657236, Length=250, Percent_Identity=34, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI221625507, Length=111, Percent_Identity=38.7387387387387, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1788882, Length=235, Percent_Identity=34.0425531914894, Blast_Score=122, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI193202570, Length=218, Percent_Identity=34.4036697247706, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI193202572, Length=216, Percent_Identity=32.4074074074074, Blast_Score=98, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6320493, Length=208, Percent_Identity=30.7692307692308, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6321836, Length=234, Percent_Identity=27.3504273504274, Blast_Score=79, Evalue=6e-16,
Organism=Drosophila melanogaster, GI21357329, Length=248, Percent_Identity=32.6612903225806, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24664922, Length=241, Percent_Identity=32.3651452282158, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24664926, Length=201, Percent_Identity=35.3233830845771, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24664918, Length=202, Percent_Identity=33.1683168316832, Blast_Score=104, Evalue=8e-23,
Organism=Drosophila melanogaster, GI21357957, Length=217, Percent_Identity=31.3364055299539, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI21357303, Length=208, Percent_Identity=31.7307692307692, Blast_Score=99, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SUHB_MYCLE (P46813)

Other databases:

- EMBL:   U15181
- EMBL:   AL583920
- PIR:   B87037
- RefSeq:   NP_301757.1
- ProteinModelPortal:   P46813
- SMR:   P46813
- EnsemblBacteria:   EBMYCT00000029171
- GeneID:   910084
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML1024
- NMPDR:   fig|272631.1.peg.629
- Leproma:   ML1024
- GeneTree:   EBGT00050000015694
- HOGENOM:   HBG730251
- OMA:   VNFIVQK
- ProtClustDB:   CLSK792016
- BioCyc:   MLEP272631:ML1024-MONOMER
- BRENDA:   3.1.3.25
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550
- PANTHER:   PTHR20854
- PRINTS:   PR00377

Pfam domain/function: PF00459 Inositol_P

EC number: =3.1.3.25

Molecular weight: Translated: 29687; Mature: 29556

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS00629 IMP_1; PS00630 IMP_2

Important sites: BINDING 83-83 BINDING 206-206 BINDING 235-235

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVPDNDPEQLRCVAESLATEAAAFVRCRRAEVFGTDLGAAGGGAVRAKSTPTDPVTVVD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEE
TETERLLRDRLAQLRPGDSILGEEGGGPADLTATPADTVTWVLDPIDGTVNFVYGIPAYA
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEECCHHHH
VSVAAQVDGVSVAGAVAEVVAGRVHSAASGLGAHVTDEYGVQVLRCSAVDDLSMALLGTG
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCEEEEECCCCHHHHHHHHCC
FAYSVVRRAAQAALLAQMLPVVRDVRRIGSAALDLCMVAAGQLDAYYEHEVQVWDCAAGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEEECCCCC
LIAAEAGACVQLPKRNGPVGGAGLVVAAAPGIADALLAALQRFNGLAPILD
EEEECCCCEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TVPDNDPEQLRCVAESLATEAAAFVRCRRAEVFGTDLGAAGGGAVRAKSTPTDPVTVVD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEE
TETERLLRDRLAQLRPGDSILGEEGGGPADLTATPADTVTWVLDPIDGTVNFVYGIPAYA
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEECCHHHH
VSVAAQVDGVSVAGAVAEVVAGRVHSAASGLGAHVTDEYGVQVLRCSAVDDLSMALLGTG
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCEEEEECCCCHHHHHHHHCC
FAYSVVRRAAQAALLAQMLPVVRDVRRIGSAALDLCMVAAGQLDAYYEHEVQVWDCAAGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEEECCCCC
LIAAEAGACVQLPKRNGPVGGAGLVVAAAPGIADALLAALQRFNGLAPILD
EEEECCCCEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002