Definition | Halothermothrix orenii H 168 chromosome, complete genome. |
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Accession | NC_011899 |
Length | 2,578,146 |
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The map label for this gene is rnjA [H]
Identifier: 220932388
GI number: 220932388
Start: 1662349
End: 1664019
Strand: Direct
Name: rnjA [H]
Synonym: Hore_15520
Alternate gene names: 220932388
Gene position: 1662349-1664019 (Clockwise)
Preceding gene: 220932363
Following gene: 220932398
Centisome position: 64.48
GC content: 44.05
Gene sequence:
>1671_bases ATGCCACAGAAAATTTCTATAATTCCTCTGGGTGGTTGTCGGGAAATAGGAAATAATATGATAGTTATTGAATCTAAAAA AGACATCATAATCCTGGATTCAGGGGTGTTATTTCCCGAGGATGATGACTTCGGGTATGAACTTATAATTCCTGATATAT CCTACCTGGTTGAAAGAAAAAAGAAAATACGGGGTATAATCTTCTCACATGGCCATGAAGACCACATTGGGGCTGTCCCG TTTCTCCTGGAGAGAATCAATCCTCCTTTGTTTGGCACTGACCTGACGATGGGATTGATAAAAAGCAAGCTGGAAGACGC CGGCCTTATAGACAGGGCCAGGCTAAAAACTGTCAATCACAGGAGCAAATTAATCCTGGGGGATTTTGAACTGGACTTTT GCCATGTCAACCACAGTATCCCGGGGGCAGTGGCCACCAGGATTAAAACCCCGGTAGGTTATATTGTTTACACCGGTGAT TATAAATTTGATCAGACCCCTGTCAACACCGGACAGACCGATTATCAGAAACTATCTGACTGGGGAAAAGAGGGAATCAG GGTCCTGCTGGGGGATAGTACCAATGCTGAACGGGAAGGGCACAGCCTTTCAGAACGGGTTGTGGCTCAAAACATCGAAG AAGGATTTAAGCTTATAAACGGGAGAATTATTGTAGCTACCTTCTCAACCAATATCCACCGCATCCAGCACATCATATCA GCCGCCCGGAAGACCGGCCGAAAGGTTGCAGTGGCCGGAAGGAGTATGTTCAATACTATTCAGGTAGCTGCTGACCTTGG TTATCTGGATATTCCACCAGGACTGTTAATAACCCTGGATGAAGCCAATAAAATGGAACCTGGTAATATAGTCCTCCTGA TGACCGGGAGCCAGGGTGAATATGGAGCAGCCCTGACCAGGCTGTCCCGTGGAGACCACCGTGATATGGAAATCAAACCC GGGGACACGGTTTTTATGTCAGCCAGTCCCATTCCGGGTAATGAAAAAGCCATCGGAAATACCATTAACAGGCTTTATAG CCTGGGGGCAGAGGTTATCTATAATGGAATGCTGGATATTCATGCCTCCGGTCATGCCTGCCAGGAAGAAATAAAACTTA TGATAAATCTGACAGGACCTGATTACCTGGTCCCGGTCCATGGTGAATTCCGCCATCTATTTCACCATGCCCAGCTGGCA CGACAGGCCGGGGTTCCCGTCCAAAATATTTTAATCCCGGACAATGGCCAGAAGATTGATGTTTTTCCTAAAAGGGTAAA AATGGGAAATAAAATTGAGGTTAATAAAACCCTTATTGAGGGTTATCGGGTCTGTGACAATGGAAAGGAAATACTGGGAG AAAGAAAAAAAATGGCAAGACAGGGGTATATAAATATCCTTATGTTTGTCAATAAAAACGGTGAATTAAAAAATAAACCG GTTATTATTTCCCGGGGCTTTACCAGCAATCGTGACTCCCGGGAACTCTTAAAAAAGGTTAAAGAAAAAGTCCAGAAACT TATTGAAGAATTTCAAAATAACAGGCACGGTGACCCAGCTGACCTGAAATCAAGGGTCAACTATGAAGTCAATAACCTGA TATATGATAAATTAAAGAGGGCCCCCCTGATTACACCGTTTATTATCCAGGTTAATCAGGATAGACGTTAA
Upstream 100 bases:
>100_bases TATATTTCTTGCCCCGGGCACCCTTTTCCTGCCTCAACAATATAATTAAATATATCTAAAATGAATATAATAATAATCAG ACTATAAGGGGGTTTTAGAT
Downstream 100 bases:
>100_bases ATAATAGACCTTAAATATAGAGGTCGAGTAAAAGACCCCTGATCTCATCTATTTTTTGAACTATTTTTAAGACATCGGCC TGCTCCTCCATGAACATCTC
Product: beta-lactamase domain-containing protein
Products: NA
Alternate protein names: RNase J1 [H]
Number of amino acids: Translated: 556; Mature: 555
Protein sequence:
>556_residues MPQKISIIPLGGCREIGNNMIVIESKKDIIILDSGVLFPEDDDFGYELIIPDISYLVERKKKIRGIIFSHGHEDHIGAVP FLLERINPPLFGTDLTMGLIKSKLEDAGLIDRARLKTVNHRSKLILGDFELDFCHVNHSIPGAVATRIKTPVGYIVYTGD YKFDQTPVNTGQTDYQKLSDWGKEGIRVLLGDSTNAEREGHSLSERVVAQNIEEGFKLINGRIIVATFSTNIHRIQHIIS AARKTGRKVAVAGRSMFNTIQVAADLGYLDIPPGLLITLDEANKMEPGNIVLLMTGSQGEYGAALTRLSRGDHRDMEIKP GDTVFMSASPIPGNEKAIGNTINRLYSLGAEVIYNGMLDIHASGHACQEEIKLMINLTGPDYLVPVHGEFRHLFHHAQLA RQAGVPVQNILIPDNGQKIDVFPKRVKMGNKIEVNKTLIEGYRVCDNGKEILGERKKMARQGYINILMFVNKNGELKNKP VIISRGFTSNRDSRELLKKVKEKVQKLIEEFQNNRHGDPADLKSRVNYEVNNLIYDKLKRAPLITPFIIQVNQDRR
Sequences:
>Translated_556_residues MPQKISIIPLGGCREIGNNMIVIESKKDIIILDSGVLFPEDDDFGYELIIPDISYLVERKKKIRGIIFSHGHEDHIGAVP FLLERINPPLFGTDLTMGLIKSKLEDAGLIDRARLKTVNHRSKLILGDFELDFCHVNHSIPGAVATRIKTPVGYIVYTGD YKFDQTPVNTGQTDYQKLSDWGKEGIRVLLGDSTNAEREGHSLSERVVAQNIEEGFKLINGRIIVATFSTNIHRIQHIIS AARKTGRKVAVAGRSMFNTIQVAADLGYLDIPPGLLITLDEANKMEPGNIVLLMTGSQGEYGAALTRLSRGDHRDMEIKP GDTVFMSASPIPGNEKAIGNTINRLYSLGAEVIYNGMLDIHASGHACQEEIKLMINLTGPDYLVPVHGEFRHLFHHAQLA RQAGVPVQNILIPDNGQKIDVFPKRVKMGNKIEVNKTLIEGYRVCDNGKEILGERKKMARQGYINILMFVNKNGELKNKP VIISRGFTSNRDSRELLKKVKEKVQKLIEEFQNNRHGDPADLKSRVNYEVNNLIYDKLKRAPLITPFIIQVNQDRR >Mature_555_residues PQKISIIPLGGCREIGNNMIVIESKKDIIILDSGVLFPEDDDFGYELIIPDISYLVERKKKIRGIIFSHGHEDHIGAVPF LLERINPPLFGTDLTMGLIKSKLEDAGLIDRARLKTVNHRSKLILGDFELDFCHVNHSIPGAVATRIKTPVGYIVYTGDY KFDQTPVNTGQTDYQKLSDWGKEGIRVLLGDSTNAEREGHSLSERVVAQNIEEGFKLINGRIIVATFSTNIHRIQHIISA ARKTGRKVAVAGRSMFNTIQVAADLGYLDIPPGLLITLDEANKMEPGNIVLLMTGSQGEYGAALTRLSRGDHRDMEIKPG DTVFMSASPIPGNEKAIGNTINRLYSLGAEVIYNGMLDIHASGHACQEEIKLMINLTGPDYLVPVHGEFRHLFHHAQLAR QAGVPVQNILIPDNGQKIDVFPKRVKMGNKIEVNKTLIEGYRVCDNGKEILGERKKMARQGYINILMFVNKNGELKNKPV IISRGFTSNRDSRELLKKVKEKVQKLIEEFQNNRHGDPADLKSRVNYEVNNLIYDKLKRAPLITPFIIQVNQDRR
Specific function: Cleaves the 5'-leader sequence of certain mRNAs. May play a role in maturation and stability of specific mRNAs. Is also required for the maturation of the 16S rRNA. Acts preferentially on 16S rRNA precursors after association of the 30S and 50S ribosomal
COG id: COG0595
COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001279 - InterPro: IPR011108 - InterPro: IPR004613 - InterPro: IPR001587 [H]
Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]
EC number: NA
Molecular weight: Translated: 62230; Mature: 62099
Theoretical pI: Translated: 9.23; Mature: 9.23
Prosite motif: PS01292 UPF0036
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPQKISIIPLGGCREIGNNMIVIESKKDIIILDSGVLFPEDDDFGYELIIPDISYLVERK CCCEEEEEECCCHHHHCCCEEEEECCCCEEEEECCEECCCCCCCCEEEECCCHHHHHHHH KKIRGIIFSHGHEDHIGAVPFLLERINPPLFGTDLTMGLIKSKLEDAGLIDRARLKTVNH HHHCEEEEECCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCC RSKLILGDFELDFCHVNHSIPGAVATRIKTPVGYIVYTGDYKFDQTPVNTGQTDYQKLSD CCEEEEEECEEEEEEECCCCCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHH WGKEGIRVLLGDSTNAEREGHSLSERVVAQNIEEGFKLINGRIIVATFSTNIHRIQHIIS HCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHH AARKTGRKVAVAGRSMFNTIQVAADLGYLDIPPGLLITLDEANKMEPGNIVLLMTGSQGE HHHHCCCEEEEECHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCCCEEEEEECCCCC YGAALTRLSRGDHRDMEIKPGDTVFMSASPIPGNEKAIGNTINRLYSLGAEVIYNGMLDI HHHHHHHHCCCCCCCEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHCHHHHHCCCEEE HASGHACQEEIKLMINLTGPDYLVPVHGEFRHLFHHAQLARQAGVPVQNILIPDNGQKID ECCCCHHHCEEEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHCCCHHEEEECCCCCEEE VFPKRVKMGNKIEVNKTLIEGYRVCDNGKEILGERKKMARQGYINILMFVNKNGELKNKP CCHHHHCCCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCC VIISRGFTSNRDSRELLKKVKEKVQKLIEEFQNNRHGDPADLKSRVNYEVNNLIYDKLKR EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHC APLITPFIIQVNQDRR CCCCCEEEEEECCCCC >Mature Secondary Structure PQKISIIPLGGCREIGNNMIVIESKKDIIILDSGVLFPEDDDFGYELIIPDISYLVERK CCEEEEEECCCHHHHCCCEEEEECCCCEEEEECCEECCCCCCCCEEEECCCHHHHHHHH KKIRGIIFSHGHEDHIGAVPFLLERINPPLFGTDLTMGLIKSKLEDAGLIDRARLKTVNH HHHCEEEEECCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCC RSKLILGDFELDFCHVNHSIPGAVATRIKTPVGYIVYTGDYKFDQTPVNTGQTDYQKLSD CCEEEEEECEEEEEEECCCCCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHH WGKEGIRVLLGDSTNAEREGHSLSERVVAQNIEEGFKLINGRIIVATFSTNIHRIQHIIS HCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHH AARKTGRKVAVAGRSMFNTIQVAADLGYLDIPPGLLITLDEANKMEPGNIVLLMTGSQGE HHHHCCCEEEEECHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCCCEEEEEECCCCC YGAALTRLSRGDHRDMEIKPGDTVFMSASPIPGNEKAIGNTINRLYSLGAEVIYNGMLDI HHHHHHHHCCCCCCCEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHCHHHHHCCCEEE HASGHACQEEIKLMINLTGPDYLVPVHGEFRHLFHHAQLARQAGVPVQNILIPDNGQKID ECCCCHHHCEEEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHCCCHHEEEECCCCCEEE VFPKRVKMGNKIEVNKTLIEGYRVCDNGKEILGERKKMARQGYINILMFVNKNGELKNKP CCHHHHCCCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCC VIISRGFTSNRDSRELLKKVKEKVQKLIEEFQNNRHGDPADLKSRVNYEVNNLIYDKLKR EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHC APLITPFIIQVNQDRR CCCCCEEEEEECCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8969500; 9384377 [H]