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The map label for this gene is insF1 [C]

Identifier: 220932213

GI number: 220932213

Start: 1467207

End: 1468040

Strand: Direct

Name: insF1 [C]

Synonym: Hore_13740

Alternate gene names: 220932213

Gene position: 1467207-1468040 (Clockwise)

Preceding gene: 220932212

Following gene: 220932220

Centisome position: 56.91

GC content: 35.25

Gene sequence:

>834_bases
GTGGAAAGGATGTGCCAGGTTTTAAATGTATCCCGGTCAGGATATTACAGCTGGTTAAGTAGAAAACCTGGTAAAAGACA
GCTTACAAATGAAAAATTAAAGTTAAAGATTGATAAAATATACTGGCAGAACAGGGGAAGATATGGTAGTCCCCGGATAC
ATAAACAGCTTAAAAAAGATGGTTATTATTACAATATTAAGCGTATTGAACGGCTAATGAGAGTAATGGGATTAAAAGCA
ATACAGAAAAGAAAGTTTAAAAGGACAACTAATTCTGACCATAATCTCCCTTCAAAAAATAATCTTCTCAAACGTAATTT
TAGTGTTACCCAACCTAATAAAGTCTGGGTATCAGACATAACATATATTCCAACAAAAGAAGGCTGGCTTTATCTTTCAG
TAGTGATTGACCTTTACTCTCGCAAGGTAGTAGGTTGGTCAATGGACAAGCATATGACAAAAAGGTTAGTGATTGATGCA
TTGGAAATGGCCGTACTAAATCGTAATCCCTCCAGGGGATTAATTTTTCATTCTGACAGAGGTAGTCAGTATGTCAGCCA
TGATTTTCAAAAAACACTGTGGAAATACGGTATTATTTCATCAATGAGCCGCAAAGGTGATTGCTGGGACAATGCAGTAG
CTGAAAGTTTTTTTGCAACACTAAAAACAGAATTGATTTTCCACAACAAGTATCAGAGCAGGGCTCAGGCAAAACGTGAT
ATATTTGAGTATATAGAGATTTTTTATAATAGGATTCGATTACATTCTTCACTAGATTATAAAAGCCCGGAAGATTACGA
GAAAGAAAGAAAAACGTCTAAACTATGTGTCTAA

Upstream 100 bases:

>100_bases
TAAAAATAGAGCGTGATATATTAAAAAAAGCAGTGCGCATCTTCTCAAAGGAACCGAAATAATATATGGTTTCATCCGGG
ATCACAGTGATGAATTTACT

Downstream 100 bases:

>100_bases
TTTATTGGGGGAACCCCAAAAATATTGAATGAATTACATAATAATTTTTTACACTTGCATATCCCTTTAAAAAACTTAAA
ATATATACAGTAATGCTTAA

Product: integrase catalytic subunit

Products: NA

Alternate protein names: ISO-S3 31 kDa protein [H]

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MERMCQVLNVSRSGYYSWLSRKPGKRQLTNEKLKLKIDKIYWQNRGRYGSPRIHKQLKKDGYYYNIKRIERLMRVMGLKA
IQKRKFKRTTNSDHNLPSKNNLLKRNFSVTQPNKVWVSDITYIPTKEGWLYLSVVIDLYSRKVVGWSMDKHMTKRLVIDA
LEMAVLNRNPSRGLIFHSDRGSQYVSHDFQKTLWKYGIISSMSRKGDCWDNAVAESFFATLKTELIFHNKYQSRAQAKRD
IFEYIEIFYNRIRLHSSLDYKSPEDYEKERKTSKLCV

Sequences:

>Translated_277_residues
MERMCQVLNVSRSGYYSWLSRKPGKRQLTNEKLKLKIDKIYWQNRGRYGSPRIHKQLKKDGYYYNIKRIERLMRVMGLKA
IQKRKFKRTTNSDHNLPSKNNLLKRNFSVTQPNKVWVSDITYIPTKEGWLYLSVVIDLYSRKVVGWSMDKHMTKRLVIDA
LEMAVLNRNPSRGLIFHSDRGSQYVSHDFQKTLWKYGIISSMSRKGDCWDNAVAESFFATLKTELIFHNKYQSRAQAKRD
IFEYIEIFYNRIRLHSSLDYKSPEDYEKERKTSKLCV
>Mature_277_residues
MERMCQVLNVSRSGYYSWLSRKPGKRQLTNEKLKLKIDKIYWQNRGRYGSPRIHKQLKKDGYYYNIKRIERLMRVMGLKA
IQKRKFKRTTNSDHNLPSKNNLLKRNFSVTQPNKVWVSDITYIPTKEGWLYLSVVIDLYSRKVVGWSMDKHMTKRLVIDA
LEMAVLNRNPSRGLIFHSDRGSQYVSHDFQKTLWKYGIISSMSRKGDCWDNAVAESFFATLKTELIFHNKYQSRAQAKRD
IFEYIEIFYNRIRLHSSLDYKSPEDYEKERKTSKLCV

Specific function: Involved in the transposition of the insertion sequence is3 [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=246, Percent_Identity=36.1788617886179, Blast_Score=164, Evalue=9e-41,
Organism=Escherichia coli, GI1788405, Length=271, Percent_Identity=43.5424354243542, Blast_Score=238, Evalue=2e-64,
Organism=Escherichia coli, GI1787263, Length=271, Percent_Identity=43.5424354243542, Blast_Score=238, Evalue=2e-64,
Organism=Escherichia coli, GI1786753, Length=271, Percent_Identity=43.5424354243542, Blast_Score=238, Evalue=2e-64,
Organism=Escherichia coli, GI1786570, Length=271, Percent_Identity=43.5424354243542, Blast_Score=238, Evalue=2e-64,
Organism=Escherichia coli, GI1786490, Length=271, Percent_Identity=43.5424354243542, Blast_Score=238, Evalue=2e-64,
Organism=Escherichia coli, GI1789981, Length=268, Percent_Identity=35.8208955223881, Blast_Score=159, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 33077; Mature: 33077

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERMCQVLNVSRSGYYSWLSRKPGKRQLTNEKLKLKIDKIYWQNRGRYGSPRIHKQLKKD
CHHHHHHHHCCCCHHHHHHHCCCCCHHHCCCHHEEEEEHHHHHCCCCCCCHHHHHHHHHC
GYYYNIKRIERLMRVMGLKAIQKRKFKRTTNSDHNLPSKNNLLKRNFSVTQPNKVWVSDI
CCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCEEEEECE
TYIPTKEGWLYLSVVIDLYSRKVVGWSMDKHMTKRLVIDALEMAVLNRNPSRGLIFHSDR
EECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCC
GSQYVSHDFQKTLWKYGIISSMSRKGDCWDNAVAESFFATLKTELIFHNKYQSRAQAKRD
CCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFEYIEIFYNRIRLHSSLDYKSPEDYEKERKTSKLCV
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2824781 [H]