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The map label for this gene is rnc [H]

Identifier: 220931875

GI number: 220931875

Start: 1121055

End: 1121765

Strand: Direct

Name: rnc [H]

Synonym: Hore_10320

Alternate gene names: 220931875

Gene position: 1121055-1121765 (Clockwise)

Preceding gene: 220931874

Following gene: 220931876

Centisome position: 43.48

GC content: 33.76

Gene sequence:

>711_bases
ATGATAAGAATTTATAATAAAAAGCTTTTAAAAAAACTGGAAGAAAAATTAAATATCAGATTTAATGATATATCCCTGTT
GCAAAAGGCTGTTACCCATAAATCCTTTGTCCACGAAAAGTCTGATCCGGACCTGGAGGATAATGAAAGGCTTGAATTTC
TGGGTGATTCAGTTTTAAGTATTGTTATAAGTACTTATTTGTATAAAAATTTCCCTGAATATAATGAAGGGGAATTGGCA
AAAATGAGGGCCTATATTGTCAGTTCTTCCCATCTTGCCTGCAAGGCCAGGGAGTTAGGTCTTGGTAAATATATTTTAAT
GGGCAAGGGGGAAGAACTGAATGGTGGTAGAGAAAGAGAATCTATTCTGGCTGACACACTGGAAGCAGTAATTGGAGCCA
TATATCTAGATCAGGGTTTTAATACTATAACCGATTTATTAATAAATTTTTTTAAAGATGATGTTAAAAAATTAGACCAG
GGGAATATTATCAGGGATTACAAAACCTATTTACAGGAATTTATTCAGAAGGATGGTAGTTGTGAAATAAAATACAATAT
TATTAATGAATATGGCCCCGATCATAATAAGAAATTTGAGGTTGGGGTTAAAGTTAATGGAAAAGAACTGGGCCGGGGGA
CCGGTTTTAGTAAAAAAGAAGCAGAACAAAAAGCGGCTAAAGATGCTCTGAGTAATTTAGGAGAAATATAA

Upstream 100 bases:

>100_bases
ATTAAAAACAGTTATGACCAATTCTTTTGGATTTGGGGGTCAGAATGCCTGTCTGGTACTTCGGAAAATTGATGAATAAG
GAACCAGGGGAGTAATTTTA

Downstream 100 bases:

>100_bases
TTATTATGAAAAATAAATTAAATATTAAACTTAACCTCCCGGGATATTTCCGGAGTTAACTACATAAGGATGTATTAAAA
AGAGTTACTCCCTGGGAGGT

Product: Ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III; RNase III [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MIRIYNKKLLKKLEEKLNIRFNDISLLQKAVTHKSFVHEKSDPDLEDNERLEFLGDSVLSIVISTYLYKNFPEYNEGELA
KMRAYIVSSSHLACKARELGLGKYILMGKGEELNGGRERESILADTLEAVIGAIYLDQGFNTITDLLINFFKDDVKKLDQ
GNIIRDYKTYLQEFIQKDGSCEIKYNIINEYGPDHNKKFEVGVKVNGKELGRGTGFSKKEAEQKAAKDALSNLGEI

Sequences:

>Translated_236_residues
MIRIYNKKLLKKLEEKLNIRFNDISLLQKAVTHKSFVHEKSDPDLEDNERLEFLGDSVLSIVISTYLYKNFPEYNEGELA
KMRAYIVSSSHLACKARELGLGKYILMGKGEELNGGRERESILADTLEAVIGAIYLDQGFNTITDLLINFFKDDVKKLDQ
GNIIRDYKTYLQEFIQKDGSCEIKYNIINEYGPDHNKKFEVGVKVNGKELGRGTGFSKKEAEQKAAKDALSNLGEI
>Mature_236_residues
MIRIYNKKLLKKLEEKLNIRFNDISLLQKAVTHKSFVHEKSDPDLEDNERLEFLGDSVLSIVISTYLYKNFPEYNEGELA
KMRAYIVSSSHLACKARELGLGKYILMGKGEELNGGRERESILADTLEAVIGAIYLDQGFNTITDLLINFFKDDVKKLDQ
GNIIRDYKTYLQEFIQKDGSCEIKYNIINEYGPDHNKKFEVGVKVNGKELGRGTGFSKKEAEQKAAKDALSNLGEI

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs [H]

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain [H]

Homologues:

Organism=Homo sapiens, GI155030234, Length=228, Percent_Identity=31.140350877193, Blast_Score=101, Evalue=5e-22,
Organism=Homo sapiens, GI155030236, Length=228, Percent_Identity=31.140350877193, Blast_Score=101, Evalue=7e-22,
Organism=Escherichia coli, GI1788920, Length=215, Percent_Identity=39.5348837209302, Blast_Score=155, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17506883, Length=229, Percent_Identity=32.3144104803493, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI193202651, Length=229, Percent_Identity=32.3144104803493, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17137682, Length=233, Percent_Identity=32.618025751073, Blast_Score=107, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907 [H]

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3 [H]

EC number: =3.1.26.3 [H]

Molecular weight: Translated: 26854; Mature: 26854

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS50137 DS_RBD ; PS00517 RNASE_3_1 ; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRIYNKKLLKKLEEKLNIRFNDISLLQKAVTHKSFVHEKSDPDLEDNERLEFLGDSVLS
CEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
IVISTYLYKNFPEYNEGELAKMRAYIVSSSHLACKARELGLGKYILMGKGEELNGGRERE
HHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCCCCCCCHHHH
SILADTLEAVIGAIYLDQGFNTITDLLINFFKDDVKKLDQGNIIRDYKTYLQEFIQKDGS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
CEIKYNIINEYGPDHNKKFEVGVKVNGKELGRGTGFSKKEAEQKAAKDALSNLGEI
CEEEEEEECCCCCCCCCEEEEEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIRIYNKKLLKKLEEKLNIRFNDISLLQKAVTHKSFVHEKSDPDLEDNERLEFLGDSVLS
CEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
IVISTYLYKNFPEYNEGELAKMRAYIVSSSHLACKARELGLGKYILMGKGEELNGGRERE
HHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCCCCCCCHHHH
SILADTLEAVIGAIYLDQGFNTITDLLINFFKDDVKKLDQGNIIRDYKTYLQEFIQKDGS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
CEIKYNIINEYGPDHNKKFEVGVKVNGKELGRGTGFSKKEAEQKAAKDALSNLGEI
CEEEEEEECCCCCCCCCEEEEEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA