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The map label for this gene is fabD [H]

Identifier: 220931871

GI number: 220931871

Start: 1117664

End: 1118593

Strand: Direct

Name: fabD [H]

Synonym: Hore_10280

Alternate gene names: 220931871

Gene position: 1117664-1118593 (Clockwise)

Preceding gene: 220931870

Following gene: 220931872

Centisome position: 43.35

GC content: 38.6

Gene sequence:

>930_bases
ATGAGTAACAAAATAGCCTTTTTATTCCCCGGTCAGGGTTCACAATATGTTGGTATGGGTCAGGAATTAATTGAACATTA
CCCTGGAACTGATGATTTTTTTAAAAAGGCAAATCATATTCTTGGTTATGATCTTAAAGAGTTATGTTTTAATGGCCCTG
AATCTAAATTAAATAATACTAAATACACTCAACCTGCCATTTTTACAGTAAGTATGATTATCTACAGTATATTGAATAGT
AATAATATATACCCTGATGTTGTAGCCGGACATAGCCTTGGTGAGTATAGTGCCCTGGCAGCGGCGGGTGTTTTTACCTT
CGAAGATGGTCTTAAACTTGTACACAGGAGAGGTAATTTAATGGATGAAGCCCTGCCGGAAGGTCAGGGGACTATGGCTG
CCATAATAGGGCTTGAAAAGAAACAGGTTTTATCTATCTGTCAGCAGGTGGATGGGGTATGTGAAGTGGCTAATTACAAT
TCACCTTCCCAGTTAGTTATAACCGGGGAAACCCCGGCGGTTCAAGAAGCTATGAAACTGGCTGAGCAAGAAGGGGCTAA
AAAAGTAGTTGGTCTTGATGTTAGTGGGCCTTTCCATTCTTCTTTAATGAAACCGGCCCGGGATAAACTTTCAAATTATA
TTAATGAAATTAATTTTAATGACCCGCAGGTACCTGTTGTAGCCAATGTAACCGGTGATTATGTTAAGGATAGTGCAGGT
ATCAAAAAGCTTTTAATAAACCAGTTGACCGGTAGTGTGCGCTGGGTGGAAAGCATGAACAGGTTATTGGAAGATGGTGT
GGATATTTTTATTGAGGTTGGTCCTGGAAGGGTATTAAAAGGATTAATGAGGAGGATCAACCGGAAGGCAAGGGTATATA
ATATAGAGAATATAAAGACCCTTAATAAATTACTAGATATATTAAAGTAA

Upstream 100 bases:

>100_bases
ATAAATGATATAAAACCGGTAGAAGATGTACTCCAGTCAATTGTCAGGGATGCCGAGAATATAATAAATAAACAATTTAA
TTTAATCGGGGTGGATAAAG

Downstream 100 bases:

>100_bases
ATAATTATTATTTTTATTGACAAAAGGTATGTTAATAATTAAAATGGGGGTTGAGATATGAATTTAAAGGGTAAAGTTGC
AGTAATTACAGGAAGCTCAA

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSNKIAFLFPGQGSQYVGMGQELIEHYPGTDDFFKKANHILGYDLKELCFNGPESKLNNTKYTQPAIFTVSMIIYSILNS
NNIYPDVVAGHSLGEYSALAAAGVFTFEDGLKLVHRRGNLMDEALPEGQGTMAAIIGLEKKQVLSICQQVDGVCEVANYN
SPSQLVITGETPAVQEAMKLAEQEGAKKVVGLDVSGPFHSSLMKPARDKLSNYINEINFNDPQVPVVANVTGDYVKDSAG
IKKLLINQLTGSVRWVESMNRLLEDGVDIFIEVGPGRVLKGLMRRINRKARVYNIENIKTLNKLLDILK

Sequences:

>Translated_309_residues
MSNKIAFLFPGQGSQYVGMGQELIEHYPGTDDFFKKANHILGYDLKELCFNGPESKLNNTKYTQPAIFTVSMIIYSILNS
NNIYPDVVAGHSLGEYSALAAAGVFTFEDGLKLVHRRGNLMDEALPEGQGTMAAIIGLEKKQVLSICQQVDGVCEVANYN
SPSQLVITGETPAVQEAMKLAEQEGAKKVVGLDVSGPFHSSLMKPARDKLSNYINEINFNDPQVPVVANVTGDYVKDSAG
IKKLLINQLTGSVRWVESMNRLLEDGVDIFIEVGPGRVLKGLMRRINRKARVYNIENIKTLNKLLDILK
>Mature_308_residues
SNKIAFLFPGQGSQYVGMGQELIEHYPGTDDFFKKANHILGYDLKELCFNGPESKLNNTKYTQPAIFTVSMIIYSILNSN
NIYPDVVAGHSLGEYSALAAAGVFTFEDGLKLVHRRGNLMDEALPEGQGTMAAIIGLEKKQVLSICQQVDGVCEVANYNS
PSQLVITGETPAVQEAMKLAEQEGAKKVVGLDVSGPFHSSLMKPARDKLSNYINEINFNDPQVPVVANVTGDYVKDSAGI
KKLLINQLTGSVRWVESMNRLLEDGVDIFIEVGPGRVLKGLMRRINRKARVYNIENIKTLNKLLDILK

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=308, Percent_Identity=34.4155844155844, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI27477045, Length=110, Percent_Identity=42.7272727272727, Blast_Score=89, Evalue=4e-18,
Organism=Escherichia coli, GI1787334, Length=287, Percent_Identity=44.9477351916376, Blast_Score=234, Evalue=6e-63,
Organism=Caenorhabditis elegans, GI71984332, Length=295, Percent_Identity=29.8305084745763, Blast_Score=136, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17550940, Length=293, Percent_Identity=29.3515358361775, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI212642053, Length=321, Percent_Identity=27.1028037383178, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24665753, Length=304, Percent_Identity=31.25, Blast_Score=151, Evalue=6e-37,
Organism=Drosophila melanogaster, GI19920632, Length=302, Percent_Identity=24.5033112582781, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221330659, Length=302, Percent_Identity=24.5033112582781, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24581345, Length=299, Percent_Identity=22.742474916388, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 34011; Mature: 33879

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKIAFLFPGQGSQYVGMGQELIEHYPGTDDFFKKANHILGYDLKELCFNGPESKLNNT
CCCCEEEEECCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHCCCCHHHCCCC
KYTQPAIFTVSMIIYSILNSNNIYPDVVAGHSLGEYSALAAAGVFTFEDGLKLVHRRGNL
CCCCHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
MDEALPEGQGTMAAIIGLEKKQVLSICQQVDGVCEVANYNSPSQLVITGETPAVQEAMKL
HHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHH
AEQEGAKKVVGLDVSGPFHSSLMKPARDKLSNYINEINFNDPQVPVVANVTGDYVKDSAG
HHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHH
IKKLLINQLTGSVRWVESMNRLLEDGVDIFIEVGPGRVLKGLMRRINRKARVYNIENIKT
HHHHHHHHHHCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCHHHEEEHHHHHH
LNKLLDILK
HHHHHHHHC
>Mature Secondary Structure 
SNKIAFLFPGQGSQYVGMGQELIEHYPGTDDFFKKANHILGYDLKELCFNGPESKLNNT
CCCEEEEECCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHCCCCHHHCCCC
KYTQPAIFTVSMIIYSILNSNNIYPDVVAGHSLGEYSALAAAGVFTFEDGLKLVHRRGNL
CCCCHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
MDEALPEGQGTMAAIIGLEKKQVLSICQQVDGVCEVANYNSPSQLVITGETPAVQEAMKL
HHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHH
AEQEGAKKVVGLDVSGPFHSSLMKPARDKLSNYINEINFNDPQVPVVANVTGDYVKDSAG
HHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHH
IKKLLINQLTGSVRWVESMNRLLEDGVDIFIEVGPGRVLKGLMRRINRKARVYNIENIKT
HHHHHHHHHHCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCHHHEEEHHHHHH
LNKLLDILK
HHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]