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The map label for this gene is fabH [H]

Identifier: 220931869

GI number: 220931869

Start: 1115713

End: 1116708

Strand: Direct

Name: fabH [H]

Synonym: Hore_10260

Alternate gene names: 220931869

Gene position: 1115713-1116708 (Clockwise)

Preceding gene: 220931868

Following gene: 220931870

Centisome position: 43.28

GC content: 42.97

Gene sequence:

>996_bases
ATGGGAAGGAGAGCAACGGTAACAGGAGTGGGTATGTATGTTCCTCCAAAGATTTTAACAAATAAAGATTTAGAGAAGAT
GGTTGATACCAGTGATGAGTGGATAACTACCAGGACCGGTATTAAAGAAAGAAGAATTGCTGCTGATGATGTGCCGACCT
CAGAACTGGCTTTAAAGGCAGCCCGGAAAGCGCTGGCTGATGCCGATTTGAAGGCAGAAGAGCTTGATTTAATTATGGTG
GCAACAGTAACCCCGGATATGTCTTTTCCATCAACTGCCTGTATTTTACAGGAAAAACTGGGGGCTGATAAGGCTGCTGC
CTTTGATATGGAGGCCGGTTGCTCAGGGTTTGTCTATGCAATGAGTGTAGCCAGTCAGTTTATAGAAACAGGTATGTACG
ATAATATCTTAATTATAGGTGCTGAAACCCTTTCCAAGATAACAGACTGGGAAGATAGAAGTACCTGTGTTCTGTTTGGA
GATGGGGCCGGTGCTGCTGTATTACAGCCAACTGAAAATGGAGGTATACTGGCCACTGAACTGGGGGCAGATGGTACCGG
TGGCAAGAGCCTGTTTATGCCAGCCGGTGGTTCCCTGAATCCAGCTGATAAAACGACAGTTGAAGAGAAAATGCATTATA
TAAAAATGGAAGGAAATCAGGTCTTTAAATTTGCTGTTAAAAAAATGGGGCAGGCTTCCCTGGATGTTATTAAAAAGGCT
GGTTTAAATCCCGATGATGTTGATTTATTTGTTCCCCACCAGGCAAATATTAGAATTATAGATGCTGCCGCCAAAAGATT
GAATTTAACCAAAGACAGGGTTTTTGTCAATTTACCTAAGTATGGAAATACTTCAGCTGCCTCTGTGCCCATTGCCCTGG
CTGAAGCTAAAGAAGAAGGTTTAATTAATAATGGTGATATAATTGTACTTGTTGCCTTTGGGGCTGGCCTGACCTGGGCA
TCTGCAATAATTAAATGGGATGAGGGGGAGAACTAA

Upstream 100 bases:

>100_bases
CTACCGCTATTAAAAATGCAATAAAAGTGGCCAAAGAGACTGTTAATAAAAATGTGGTAGGATTAATTAAACAAGAAATT
AATAAGGATGGTGAGTAAGT

Downstream 100 bases:

>100_bases
ATGGGATTGAAAACAGAATTATGTTCACTCCTTGATATAAAATATCCAATTTTACAGGGGGGTATGGCCTGGGTAGCTAC
CGGTGAGCTGGCAGCAGCTG

Product: 3-oxoacyl-(acyl-carrier-protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MGRRATVTGVGMYVPPKILTNKDLEKMVDTSDEWITTRTGIKERRIAADDVPTSELALKAARKALADADLKAEELDLIMV
ATVTPDMSFPSTACILQEKLGADKAAAFDMEAGCSGFVYAMSVASQFIETGMYDNILIIGAETLSKITDWEDRSTCVLFG
DGAGAAVLQPTENGGILATELGADGTGGKSLFMPAGGSLNPADKTTVEEKMHYIKMEGNQVFKFAVKKMGQASLDVIKKA
GLNPDDVDLFVPHQANIRIIDAAAKRLNLTKDRVFVNLPKYGNTSAASVPIALAEAKEEGLINNGDIIVLVAFGAGLTWA
SAIIKWDEGEN

Sequences:

>Translated_331_residues
MGRRATVTGVGMYVPPKILTNKDLEKMVDTSDEWITTRTGIKERRIAADDVPTSELALKAARKALADADLKAEELDLIMV
ATVTPDMSFPSTACILQEKLGADKAAAFDMEAGCSGFVYAMSVASQFIETGMYDNILIIGAETLSKITDWEDRSTCVLFG
DGAGAAVLQPTENGGILATELGADGTGGKSLFMPAGGSLNPADKTTVEEKMHYIKMEGNQVFKFAVKKMGQASLDVIKKA
GLNPDDVDLFVPHQANIRIIDAAAKRLNLTKDRVFVNLPKYGNTSAASVPIALAEAKEEGLINNGDIIVLVAFGAGLTWA
SAIIKWDEGEN
>Mature_330_residues
GRRATVTGVGMYVPPKILTNKDLEKMVDTSDEWITTRTGIKERRIAADDVPTSELALKAARKALADADLKAEELDLIMVA
TVTPDMSFPSTACILQEKLGADKAAAFDMEAGCSGFVYAMSVASQFIETGMYDNILIIGAETLSKITDWEDRSTCVLFGD
GAGAAVLQPTENGGILATELGADGTGGKSLFMPAGGSLNPADKTTVEEKMHYIKMEGNQVFKFAVKKMGQASLDVIKKAG
LNPDDVDLFVPHQANIRIIDAAAKRLNLTKDRVFVNLPKYGNTSAASVPIALAEAKEEGLINNGDIIVLVAFGAGLTWAS
AIIKWDEGEN

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=320, Percent_Identity=45.3125, Blast_Score=291, Evalue=3e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 35295; Mature: 35164

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRRATVTGVGMYVPPKILTNKDLEKMVDTSDEWITTRTGIKERRIAADDVPTSELALKA
CCCEEEEEEECEECCCHHHCCCHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHH
ARKALADADLKAEELDLIMVATVTPDMSFPSTACILQEKLGADKAAAFDMEAGCSGFVYA
HHHHHHCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHCCCHHEEEECCCCCCHHHHH
MSVASQFIETGMYDNILIIGAETLSKITDWEDRSTCVLFGDGAGAAVLQPTENGGILATE
HHHHHHHHHCCCCCCEEEEEHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCCEEEEE
LGADGTGGKSLFMPAGGSLNPADKTTVEEKMHYIKMEGNQVFKFAVKKMGQASLDVIKKA
CCCCCCCCCEEEEECCCCCCCCCHHHHHHHHEEEEECCCHHHHHHHHHCCHHHHHHHHHC
GLNPDDVDLFVPHQANIRIIDAAAKRLNLTKDRVFVNLPKYGNTSAASVPIALAEAKEEG
CCCCCCEEEEECCCCCEEEEECHHHHCCCCCCEEEEECCCCCCCCCCCCEEEEECHHHCC
LINNGDIIVLVAFGAGLTWASAIIKWDEGEN
CCCCCCEEEEEEECCCHHEEHHEEEECCCCC
>Mature Secondary Structure 
GRRATVTGVGMYVPPKILTNKDLEKMVDTSDEWITTRTGIKERRIAADDVPTSELALKA
CCEEEEEEECEECCCHHHCCCHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHH
ARKALADADLKAEELDLIMVATVTPDMSFPSTACILQEKLGADKAAAFDMEAGCSGFVYA
HHHHHHCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHCCCHHEEEECCCCCCHHHHH
MSVASQFIETGMYDNILIIGAETLSKITDWEDRSTCVLFGDGAGAAVLQPTENGGILATE
HHHHHHHHHCCCCCCEEEEEHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCCEEEEE
LGADGTGGKSLFMPAGGSLNPADKTTVEEKMHYIKMEGNQVFKFAVKKMGQASLDVIKKA
CCCCCCCCCEEEEECCCCCCCCCHHHHHHHHEEEEECCCHHHHHHHHHCCHHHHHHHHHC
GLNPDDVDLFVPHQANIRIIDAAAKRLNLTKDRVFVNLPKYGNTSAASVPIALAEAKEEG
CCCCCCEEEEECCCCCEEEEECHHHHCCCCCCEEEEECCCCCCCCCCCCEEEEECHHHCC
LINNGDIIVLVAFGAGLTWASAIIKWDEGEN
CCCCCCEEEEEEECCCHHEEHHEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]