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The map label for this gene is radA [H]

Identifier: 220918698

GI number: 220918698

Start: 4026366

End: 4027754

Strand: Direct

Name: radA [H]

Synonym: A2cp1_3606

Alternate gene names: 220918698

Gene position: 4026366-4027754 (Clockwise)

Preceding gene: 220918696

Following gene: 220918699

Centisome position: 80.06

GC content: 75.81

Gene sequence:

>1389_bases
ATGTCGCGCGCCGCCCCGAGGGTCCGCACCGTGTTCGCCTGCGCCGAGTGCGGGCAGCAGAGCCCGAAGTGGCTCGGCCA
GTGCCCCGCCTGCAAGCAGTGGAACACGCTGCAGGAGGAGATCGCCGCCCCGGAGCCGAAGGTCGGCGCCGCGCCGCGCG
GCTGGGGCACGCACGCCGCGGCGAAGCCGCTGCCGCTGCGCGAGGTGGAGGCGCGCGAGGAGCAGCGGCAGCGCACCGGG
ATCGGCGAGCTGGACCGGGTGCTGGGCGGGGGCGTGGTGCCCGGCGCGCTCGTGCTCCTCGGCGGTGACCCCGGCATCGG
CAAGTCCACGCTGGTCCTGGCCGCGCTCGACCGCGTGGCCCGGGCGAACCCCGACCGCCCGGTGCTGTACGTCTCCGGCG
AGGAGTCGGCGCGGCAGGTGAAGCTCCGGGCCGACCGGCTCGGCGTCGCCGCCCGGAACCTCCAGGTGCTCGCCGAGACC
GACGCGCTCAAGGTGCTCCAGGCCGCCGAGGCGCTCGCCCCGGCCGCCGTGGCGGTGGACTCGATCCAGACGCAGTACCT
GCCCGAACTGCAGAGCGCGCCCGGCACCGTCACGCAGATCCGCGAGGTGACCGCGCGGCTCATGGCGCTCGCCAAGACCA
CCGAGACGCCGATCTTCCTCATCGGGCACGTCACCAAGGACGGCAGCATCGCCGGGCCGCGCGTGCTCGAGCACATGGTG
GACACGGTCCTCTACTTCGAGGGCGGCGGCGCCCACCCGTACCGCGTGCTCCGCGCGCACAAGAACCGCTTCGGCTCGGC
CAGCGAGATCGGCGTCTTCGAGATGAAGGCGGGCGGGCTCGCGGAGGTGGCGAACCCGTCGGCGCTGTTCCTGGCCGAGC
GCCCGGAGGACGCGCCCGGGAGCGCCGTGACGGCGGTGCTGAACGGCACGCGCACGGTGCTGGTCGAGGTGCAGGCGCTG
GTGGCGCCCACCGGCTACGGCACCCCGCGGCGGACCGCGCTGGGCGTGGACGGCAACCGCGTGGCGCTGCTCGCGGCGGT
GCTCGAGAAGAAGGTCGGGCTGGAGATCCTGCCCTGCGACCTGTTCGTCAACGTGGCCGGCGGGCTGTCGGTGGACGATC
CCGCCGCCGACCTCGCCGTGGTCGCCGCCCTCGCCTCGAGCTTCCGGGAGCGCGCCCTGCCGGCGCGGACGCTGGTGCTG
GGCGAGGTGGGCCTGGCGGGCGAGGTCCGGGCGGTGTCGCAGCCCGGGATCCGCCTGGCGGAGGCGGCGCGCCTCGGCTT
CCAGCGCGCGATCGTCCCCGCCGCCAGCCTCCGGCACGCCGACGCGCCCGACGGGATCGAGCTGGTGGGCGTCACGACCG
TCGCCGACGCCCTCGACCGGCTCGCGTAG

Upstream 100 bases:

>100_bases
GCGTCGAGCGGCGCGGAGGATCGTGCATCGCGGGCCGCATCGGCAAGAGACGGAGCGGCGGGCGCCGACATGTCGGACGT
GCGTGCTAACGCCTGCTTCC

Downstream 100 bases:

>100_bases
CCCACACCCGCCCCCACGGGAACGGGTCGCCGGGTTGCGCCGGTGCGATCCCTCTCGCAAGATGATCCTGCGATGAGCCA
CGTCGTCCGCCGCCTCCGCC

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MSRAAPRVRTVFACAECGQQSPKWLGQCPACKQWNTLQEEIAAPEPKVGAAPRGWGTHAAAKPLPLREVEAREEQRQRTG
IGELDRVLGGGVVPGALVLLGGDPGIGKSTLVLAALDRVARANPDRPVLYVSGEESARQVKLRADRLGVAARNLQVLAET
DALKVLQAAEALAPAAVAVDSIQTQYLPELQSAPGTVTQIREVTARLMALAKTTETPIFLIGHVTKDGSIAGPRVLEHMV
DTVLYFEGGGAHPYRVLRAHKNRFGSASEIGVFEMKAGGLAEVANPSALFLAERPEDAPGSAVTAVLNGTRTVLVEVQAL
VAPTGYGTPRRTALGVDGNRVALLAAVLEKKVGLEILPCDLFVNVAGGLSVDDPAADLAVVAALASSFRERALPARTLVL
GEVGLAGEVRAVSQPGIRLAEAARLGFQRAIVPAASLRHADAPDGIELVGVTTVADALDRLA

Sequences:

>Translated_462_residues
MSRAAPRVRTVFACAECGQQSPKWLGQCPACKQWNTLQEEIAAPEPKVGAAPRGWGTHAAAKPLPLREVEAREEQRQRTG
IGELDRVLGGGVVPGALVLLGGDPGIGKSTLVLAALDRVARANPDRPVLYVSGEESARQVKLRADRLGVAARNLQVLAET
DALKVLQAAEALAPAAVAVDSIQTQYLPELQSAPGTVTQIREVTARLMALAKTTETPIFLIGHVTKDGSIAGPRVLEHMV
DTVLYFEGGGAHPYRVLRAHKNRFGSASEIGVFEMKAGGLAEVANPSALFLAERPEDAPGSAVTAVLNGTRTVLVEVQAL
VAPTGYGTPRRTALGVDGNRVALLAAVLEKKVGLEILPCDLFVNVAGGLSVDDPAADLAVVAALASSFRERALPARTLVL
GEVGLAGEVRAVSQPGIRLAEAARLGFQRAIVPAASLRHADAPDGIELVGVTTVADALDRLA
>Mature_461_residues
SRAAPRVRTVFACAECGQQSPKWLGQCPACKQWNTLQEEIAAPEPKVGAAPRGWGTHAAAKPLPLREVEAREEQRQRTGI
GELDRVLGGGVVPGALVLLGGDPGIGKSTLVLAALDRVARANPDRPVLYVSGEESARQVKLRADRLGVAARNLQVLAETD
ALKVLQAAEALAPAAVAVDSIQTQYLPELQSAPGTVTQIREVTARLMALAKTTETPIFLIGHVTKDGSIAGPRVLEHMVD
TVLYFEGGGAHPYRVLRAHKNRFGSASEIGVFEMKAGGLAEVANPSALFLAERPEDAPGSAVTAVLNGTRTVLVEVQALV
APTGYGTPRRTALGVDGNRVALLAAVLEKKVGLEILPCDLFVNVAGGLSVDDPAADLAVVAALASSFRERALPARTLVLG
EVGLAGEVRAVSQPGIRLAEAARLGFQRAIVPAASLRHADAPDGIELVGVTTVADALDRLA

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=461, Percent_Identity=47.2885032537961, Blast_Score=408, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 48253; Mature: 48122

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRAAPRVRTVFACAECGQQSPKWLGQCPACKQWNTLQEEIAAPEPKVGAAPRGWGTHAA
CCCCCCHHHHHHHHHHHCCCCCHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCC
AKPLPLREVEAREEQRQRTGIGELDRVLGGGVVPGALVLLGGDPGIGKSTLVLAALDRVA
CCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
RANPDRPVLYVSGEESARQVKLRADRLGVAARNLQVLAETDALKVLQAAEALAPAAVAVD
HCCCCCCEEEECCCCCHHHHHHHHHHHCHHHHCEEEEEHHHHHHHHHHHHHHHHHHHHHH
SIQTQYLPELQSAPGTVTQIREVTARLMALAKTTETPIFLIGHVTKDGSIAGPRVLEHMV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHH
DTVLYFEGGGAHPYRVLRAHKNRFGSASEIGVFEMKAGGLAEVANPSALFLAERPEDAPG
HHEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHCCCCEEEEEECCCCCCC
SAVTAVLNGTRTVLVEVQALVAPTGYGTPRRTALGVDGNRVALLAAVLEKKVGLEILPCD
CEEEEECCCCEEEEEEEEHHHCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCEEEEHE
LFVNVAGGLSVDDPAADLAVVAALASSFRERALPARTLVLGEVGLAGEVRAVSQPGIRLA
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCCCCEEECCCCCCHHH
EAARLGFQRAIVPAASLRHADAPDGIELVGVTTVADALDRLA
HHHHHHHHHHHCCHHHHCCCCCCCCEEEEEHHHHHHHHHHCC
>Mature Secondary Structure 
SRAAPRVRTVFACAECGQQSPKWLGQCPACKQWNTLQEEIAAPEPKVGAAPRGWGTHAA
CCCCCHHHHHHHHHHHCCCCCHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCC
AKPLPLREVEAREEQRQRTGIGELDRVLGGGVVPGALVLLGGDPGIGKSTLVLAALDRVA
CCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
RANPDRPVLYVSGEESARQVKLRADRLGVAARNLQVLAETDALKVLQAAEALAPAAVAVD
HCCCCCCEEEECCCCCHHHHHHHHHHHCHHHHCEEEEEHHHHHHHHHHHHHHHHHHHHHH
SIQTQYLPELQSAPGTVTQIREVTARLMALAKTTETPIFLIGHVTKDGSIAGPRVLEHMV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHH
DTVLYFEGGGAHPYRVLRAHKNRFGSASEIGVFEMKAGGLAEVANPSALFLAERPEDAPG
HHEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHCCCCEEEEEECCCCCCC
SAVTAVLNGTRTVLVEVQALVAPTGYGTPRRTALGVDGNRVALLAAVLEKKVGLEILPCD
CEEEEECCCCEEEEEEEEHHHCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCEEEEHE
LFVNVAGGLSVDDPAADLAVVAALASSFRERALPARTLVLGEVGLAGEVRAVSQPGIRLA
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCCCCEEECCCCCCHHH
EAARLGFQRAIVPAASLRHADAPDGIELVGVTTVADALDRLA
HHHHHHHHHHHCCHHHHCCCCCCCCEEEEEHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 8016066 [H]