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The map label for this gene is sir1 [H]

Identifier: 220918442

GI number: 220918442

Start: 3723826

End: 3725643

Strand: Direct

Name: sir1 [H]

Synonym: A2cp1_3346

Alternate gene names: 220918442

Gene position: 3723826-3725643 (Clockwise)

Preceding gene: 220918441

Following gene: 220918448

Centisome position: 74.04

GC content: 77.83

Gene sequence:

>1818_bases
ATGACCGCCACGCCCGCCACCCCGCGCGACCGCGCCTCCTTCGCGGACGACGCCGAGATCTCCGCCTTCGTCGACACGCT
GGGCCGCTTCGAGCGCGGCGAGCTCGACGCCGAGGCCTGGCGCGCGTACCGCGTTCCCCGCGGCGTCTACGGCCAGCGCC
AGGACGGCGTCCACATGCTGCGCATCAAGCTGCCGCAGGGCGCCGTGACCGGCGCGCAGCTCCGGGCGATCGCCGACGTC
GCCACCCGCTGCTCGCGCGGCTTCGGGCACGTCACCACGCGCCAGAACTTCCAGCTCAACTACGTCCGCCCCGCCGACCT
CGAGCCCGCCATGCGGCGGCTCGCCGAGGCCGGCATCACCACCTCGGGCGCGTGCGGCAACACGGTGCGCAACGTGCTCG
CCTGCCCGCGCGCCGGCGTCTCGCCGGACGAGGTCTTCGACGTGACCCCGTACGCGGAGGCGTTCACCCGTCACTTCCTG
CGCCACCCGCTCGGCCACGCGCTTCCCCGCAAGTTCAAGGTGGCGTTCGAGGGCTGCGCCCGCGACCACGTGGCGACCGC
CATCCAGGACCTCGGCTTCCGCGCCCGCCTGCGCGACGGCGCGCGGGGGTTCGCGGTGACGGTGGCCGGCGGGACCTCGT
CGCTGTGCACCGTCGGCGCGCTCCTGGTGGACTTCCTGCCGGCCGCGGACGTCCTCGCGCTGGGCGAGGCGGTGGTCCGG
GTGTTCCACGCGCGCGGCGATCGCGTGAACCGGCACCGCAACCGGCTCAAGTTCCTGGTCCGCGCGCTCGGCTTCGAGCC
GTTCCGCGCGCTCGTCCTGGCGGAGCTGGCGCAGGTGCGGGCCGAGGGCGCCCCGGCGCTGCCGTTCGACCCCGAGCGCC
CGCCGGTCGAGGCTCCGCCCGCCACCGCGCGCCCGCCCGCGCCCTCGGTCGCCGACCTCGCCGCGCGGGTTCGCGGCGCC
CGGCTCCGCGGGCCGGGCGAGCCGCCGCCGCTCCGGATCGTCACCGAGCCCGCGCCGGCCGCGCTGGCGGCGTTCCGCGC
CACCAACGTGCTCCCGCAGCGGCAGGCCGGCCACGCCATCGTGGCGGTGTCGCTCGCCCAGGGCGACGCGACCGCGGCCC
AGCTCGAGGCGCTCGCGACGCTGGCCGAGGCCTACGGGGACGGCGCGGTGCGGTTCACCAGCGGCGGCCACGTGCTCCTG
CGCTGGGTCCGCGAGGAGGACGTGCCGGCGCTCCACGCGCGGCTCTCGGCCGCCGGCCTCGGGCGCGACGGCGCCGGGAC
CGCGGCAGACGTGGTCGCGTGCCCGGGCGCGGACGTGTGCCGCCTGGCGGTGACGCGCACCCGCGCGCTCGCGCGCCTGG
TCGAGGACGAGGTGCGGCACGCCGTTTCGGGCGCCGGCACGGCGGCGCTGCCCGTCGCCATGTCCGGGTGCCCGAACGGC
TGCAGCCAGCACCACCTCGCCGCCATCGGGCTGCAGGGCAGCGCGCGCAAGCTGGGCGGCCGCGCCGTGCCGCAGTACTT
CGTGCTGCTCGGCGGCCACGTGGACGCGGGGGGCGCCACGTTCGGCCGGCTCGCCGCCAAGGTGCCGGCGCGGCGCATCC
CCGAGGCGGTGGCGCGGCTGACGTCGCTCTACCTCGCCGAGCGCCACGCCGGCGAGGCCGCCGGGCCGTTCTTTGCGCGC
GCCCTCGACCGCGCGAAGACGATCCTGGCGGACTACGAGCAGCTGCGGCTCGAGGACACCCGGCCCGAGGACTTCGTCGA
GCCGGGCGCCACCGAGGACTTCCGCCCCGGCGCGGACGCCGGGGAACGCGCCGCGTAG

Upstream 100 bases:

>100_bases
CGTGGTCGGGGCCGTCGCCGCCCTCTCCCTCCGCTCCCCGCACTCCACCGAAGCGCAGCCCGCCGCCCGCGCCGACGCCC
GGCCGACCTGAAAGGACCCC

Downstream 100 bases:

>100_bases
CGCTCCCGCGCATCACGCGGGACGTGCGCGGTCGTGCGATCGCCCCGGCGCCGCGCGACGGTCAGGAGCCGTGCTGCGCG
GGGTCCATCATCGGGCAGCC

Product: nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 605; Mature: 604

Protein sequence:

>605_residues
MTATPATPRDRASFADDAEISAFVDTLGRFERGELDAEAWRAYRVPRGVYGQRQDGVHMLRIKLPQGAVTGAQLRAIADV
ATRCSRGFGHVTTRQNFQLNYVRPADLEPAMRRLAEAGITTSGACGNTVRNVLACPRAGVSPDEVFDVTPYAEAFTRHFL
RHPLGHALPRKFKVAFEGCARDHVATAIQDLGFRARLRDGARGFAVTVAGGTSSLCTVGALLVDFLPAADVLALGEAVVR
VFHARGDRVNRHRNRLKFLVRALGFEPFRALVLAELAQVRAEGAPALPFDPERPPVEAPPATARPPAPSVADLAARVRGA
RLRGPGEPPPLRIVTEPAPAALAAFRATNVLPQRQAGHAIVAVSLAQGDATAAQLEALATLAEAYGDGAVRFTSGGHVLL
RWVREEDVPALHARLSAAGLGRDGAGTAADVVACPGADVCRLAVTRTRALARLVEDEVRHAVSGAGTAALPVAMSGCPNG
CSQHHLAAIGLQGSARKLGGRAVPQYFVLLGGHVDAGGATFGRLAAKVPARRIPEAVARLTSLYLAERHAGEAAGPFFAR
ALDRAKTILADYEQLRLEDTRPEDFVEPGATEDFRPGADAGERAA

Sequences:

>Translated_605_residues
MTATPATPRDRASFADDAEISAFVDTLGRFERGELDAEAWRAYRVPRGVYGQRQDGVHMLRIKLPQGAVTGAQLRAIADV
ATRCSRGFGHVTTRQNFQLNYVRPADLEPAMRRLAEAGITTSGACGNTVRNVLACPRAGVSPDEVFDVTPYAEAFTRHFL
RHPLGHALPRKFKVAFEGCARDHVATAIQDLGFRARLRDGARGFAVTVAGGTSSLCTVGALLVDFLPAADVLALGEAVVR
VFHARGDRVNRHRNRLKFLVRALGFEPFRALVLAELAQVRAEGAPALPFDPERPPVEAPPATARPPAPSVADLAARVRGA
RLRGPGEPPPLRIVTEPAPAALAAFRATNVLPQRQAGHAIVAVSLAQGDATAAQLEALATLAEAYGDGAVRFTSGGHVLL
RWVREEDVPALHARLSAAGLGRDGAGTAADVVACPGADVCRLAVTRTRALARLVEDEVRHAVSGAGTAALPVAMSGCPNG
CSQHHLAAIGLQGSARKLGGRAVPQYFVLLGGHVDAGGATFGRLAAKVPARRIPEAVARLTSLYLAERHAGEAAGPFFAR
ALDRAKTILADYEQLRLEDTRPEDFVEPGATEDFRPGADAGERAA
>Mature_604_residues
TATPATPRDRASFADDAEISAFVDTLGRFERGELDAEAWRAYRVPRGVYGQRQDGVHMLRIKLPQGAVTGAQLRAIADVA
TRCSRGFGHVTTRQNFQLNYVRPADLEPAMRRLAEAGITTSGACGNTVRNVLACPRAGVSPDEVFDVTPYAEAFTRHFLR
HPLGHALPRKFKVAFEGCARDHVATAIQDLGFRARLRDGARGFAVTVAGGTSSLCTVGALLVDFLPAADVLALGEAVVRV
FHARGDRVNRHRNRLKFLVRALGFEPFRALVLAELAQVRAEGAPALPFDPERPPVEAPPATARPPAPSVADLAARVRGAR
LRGPGEPPPLRIVTEPAPAALAAFRATNVLPQRQAGHAIVAVSLAQGDATAAQLEALATLAEAYGDGAVRFTSGGHVLLR
WVREEDVPALHARLSAAGLGRDGAGTAADVVACPGADVCRLAVTRTRALARLVEDEVRHAVSGAGTAALPVAMSGCPNGC
SQHHLAAIGLQGSARKLGGRAVPQYFVLLGGHVDAGGATFGRLAAKVPARRIPEAVARLTSLYLAERHAGEAAGPFFARA
LDRAKTILADYEQLRLEDTRPEDFVEPGATEDFRPGADAGERAA

Specific function: This Enzyme Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. [C]

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

Organism=Escherichia coli, GI1789122, Length=266, Percent_Identity=25.187969924812, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005117
- InterPro:   IPR006067
- InterPro:   IPR006066 [H]

Pfam domain/function: PF01077 NIR_SIR; PF03460 NIR_SIR_ferr [H]

EC number: =1.8.7.1 [H]

Molecular weight: Translated: 63982; Mature: 63851

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATPATPRDRASFADDAEISAFVDTLGRFERGELDAEAWRAYRVPRGVYGQRQDGVHML
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEE
RIKLPQGAVTGAQLRAIADVATRCSRGFGHVTTRQNFQLNYVRPADLEPAMRRLAEAGIT
EEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHCCCC
TSGACGNTVRNVLACPRAGVSPDEVFDVTPYAEAFTRHFLRHPLGHALPRKFKVAFEGCA
CCCCCHHHHHHHHHCCCCCCCHHHEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
RDHVATAIQDLGFRARLRDGARGFAVTVAGGTSSLCTVGALLVDFLPAADVLALGEAVVR
HHHHHHHHHHCCCHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHHHH
VFHARGDRVNRHRNRLKFLVRALGFEPFRALVLAELAQVRAEGAPALPFDPERPPVEAPP
HHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
ATARPPAPSVADLAARVRGARLRGPGEPPPLRIVTEPAPAALAAFRATNVLPQRQAGHAI
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCEE
VAVSLAQGDATAAQLEALATLAEAYGDGAVRFTSGGHVLLRWVREEDVPALHARLSAAGL
EEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEHHHCCCHHHHHHHHHHCC
GRDGAGTAADVVACPGADVCRLAVTRTRALARLVEDEVRHAVSGAGTAALPVAMSGCPNG
CCCCCCCCHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCC
CSQHHLAAIGLQGSARKLGGRAVPQYFVLLGGHVDAGGATFGRLAAKVPARRIPEAVARL
CCCCCEEEEECCCCHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHH
TSLYLAERHAGEAAGPFFARALDRAKTILADYEQLRLEDTRPEDFVEPGATEDFRPGADA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCC
GERAA
CCCCC
>Mature Secondary Structure 
TATPATPRDRASFADDAEISAFVDTLGRFERGELDAEAWRAYRVPRGVYGQRQDGVHML
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEE
RIKLPQGAVTGAQLRAIADVATRCSRGFGHVTTRQNFQLNYVRPADLEPAMRRLAEAGIT
EEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHCCCC
TSGACGNTVRNVLACPRAGVSPDEVFDVTPYAEAFTRHFLRHPLGHALPRKFKVAFEGCA
CCCCCHHHHHHHHHCCCCCCCHHHEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
RDHVATAIQDLGFRARLRDGARGFAVTVAGGTSSLCTVGALLVDFLPAADVLALGEAVVR
HHHHHHHHHHCCCHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHHHH
VFHARGDRVNRHRNRLKFLVRALGFEPFRALVLAELAQVRAEGAPALPFDPERPPVEAPP
HHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
ATARPPAPSVADLAARVRGARLRGPGEPPPLRIVTEPAPAALAAFRATNVLPQRQAGHAI
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCEE
VAVSLAQGDATAAQLEALATLAEAYGDGAVRFTSGGHVLLRWVREEDVPALHARLSAAGL
EEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEHHHCCCHHHHHHHHHHCC
GRDGAGTAADVVACPGADVCRLAVTRTRALARLVEDEVRHAVSGAGTAALPVAMSGCPNG
CCCCCCCCHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCC
CSQHHLAAIGLQGSARKLGGRAVPQYFVLLGGHVDAGGATFGRLAAKVPARRIPEAVARL
CCCCCEEEEECCCCHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHH
TSLYLAERHAGEAAGPFFARALDRAKTILADYEQLRLEDTRPEDFVEPGATEDFRPGADA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCC
GERAA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA