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The map label for this gene is ybhR [H]

Identifier: 220918405

GI number: 220918405

Start: 3685005

End: 3686156

Strand: Direct

Name: ybhR [H]

Synonym: A2cp1_3309

Alternate gene names: 220918405

Gene position: 3685005-3686156 (Clockwise)

Preceding gene: 220918404

Following gene: 220918406

Centisome position: 73.27

GC content: 73.7

Gene sequence:

>1152_bases
GTGACCCCCCGACGCCCCAGGCCCTCGGCGCGCGTGCAGTTCCTGGCGGTGTTCCGCAAGGAGGTCCGCCAGACGGCGCG
CGACAAGCGCATGATGGCGGTGCTGGTGATCGCGCCGCTGCTGCAGACGGTGGTGTTCGGGTTCGCGGCGAACTTCGACG
TGGACCGGGTGCGCACGGTGGTGCTCGACCGCGACCGCACCGACGTGTCTCGCGAGCACGCGCGGCGCCTGCTCGCCGAC
GGGACGCTGATCCGCGCCGGCGACACCGCCTCGGCGGTCGAGGCCGAGCTGCGGGTGCACCGGGGCGAGGCCGCCGCGGC
GGTGATGTTCCCGGAGCGGCTCGCCGCCGACCTGGCCGCCGGCCGGCCGGCGGAGGTGCAGGTGCTCATCGACGGCGCCG
ACCCGAACCGCTCCACGGTGGCCGCCGACGCGGTGGCGCGCTACTTCGGCGGCGTGGGCGAGCGCCTGGCGCGGGAGGCG
CTCGCCGCGCGCGGCGCCACGCCGCCCGGCCAGCTCGCGCTCGTGCCGCGGCTCTTCTACAACCCCGGGCTCGACTCCCC
GCCCTACATGGTCCCCGGCATCGCGGCGCTGCTTCTGGTGGTGGTGACCACGATCGTGAGCGCGATGGGGCTCGCGCGCG
AGCGCGAGATGGGCACGCTGGAGCAGGTGCTGGTCACGCCCATCCGGCCCGCCGTGCTGCTCGCCGGCAAGATCGCGCCG
TACGTGATCATCGGGTTCGTGAACCTGGCGCTGCTGGTGGGGGTCGCCAGCCTGATCTTCGGGGTGCCCATCCGCGGACC
GCTCCCGGTCCTGGCGCTCGGCACGCTCCTCTACCTGCTCACCACCCTCGGCGTGGGGCTGTTCATCTCGACCATCTCGA
AGAACCAGCAGCAGTCGTTCCTGGGCGGCTTCCTGTTCCTGGTCCCGGCGCTGCTGCTGTCCGGCGTCATGACGCCGGTG
GCCGCGATGCCCGGCTGGCTCCGGGCCATCACCTTCGTGAACCCGGTGCGCCACTTCGCCACCGTGATGCGCGGCTCGCT
GCTGCGGGGCGCCGGCCTGGCCGACCTGGCGATCCCCCTCACGGCGCTCGCGGTCATCGGCTCGGCCATCTTCGTCCTCT
CCGCGCTCCGCTTCCGCAAGACCCTGAGCTGA

Upstream 100 bases:

>100_bases
GGAACGGCCTCGACGTGCTCTGGCCCGACCTGCTCGCGGTGGTGGCGTTCGCGCTCCTCGTGATCGCGCTCTCCACCGCG
CGCTTCAAGCGGAGGCTCGC

Downstream 100 bases:

>100_bases
CCCGGGGCGGCGGCCCGGCCTACCGCGCGGGGTGCGACCCGACTTCCGCTGACCGGGGGCGGGGCGAGGCGCAGTATGAC
GATCCGGCGGCGCGCCATGT

Product: ABC-2 type transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MTPRRPRPSARVQFLAVFRKEVRQTARDKRMMAVLVIAPLLQTVVFGFAANFDVDRVRTVVLDRDRTDVSREHARRLLAD
GTLIRAGDTASAVEAELRVHRGEAAAAVMFPERLAADLAAGRPAEVQVLIDGADPNRSTVAADAVARYFGGVGERLAREA
LAARGATPPGQLALVPRLFYNPGLDSPPYMVPGIAALLLVVVTTIVSAMGLAREREMGTLEQVLVTPIRPAVLLAGKIAP
YVIIGFVNLALLVGVASLIFGVPIRGPLPVLALGTLLYLLTTLGVGLFISTISKNQQQSFLGGFLFLVPALLLSGVMTPV
AAMPGWLRAITFVNPVRHFATVMRGSLLRGAGLADLAIPLTALAVIGSAIFVLSALRFRKTLS

Sequences:

>Translated_383_residues
MTPRRPRPSARVQFLAVFRKEVRQTARDKRMMAVLVIAPLLQTVVFGFAANFDVDRVRTVVLDRDRTDVSREHARRLLAD
GTLIRAGDTASAVEAELRVHRGEAAAAVMFPERLAADLAAGRPAEVQVLIDGADPNRSTVAADAVARYFGGVGERLAREA
LAARGATPPGQLALVPRLFYNPGLDSPPYMVPGIAALLLVVVTTIVSAMGLAREREMGTLEQVLVTPIRPAVLLAGKIAP
YVIIGFVNLALLVGVASLIFGVPIRGPLPVLALGTLLYLLTTLGVGLFISTISKNQQQSFLGGFLFLVPALLLSGVMTPV
AAMPGWLRAITFVNPVRHFATVMRGSLLRGAGLADLAIPLTALAVIGSAIFVLSALRFRKTLS
>Mature_382_residues
TPRRPRPSARVQFLAVFRKEVRQTARDKRMMAVLVIAPLLQTVVFGFAANFDVDRVRTVVLDRDRTDVSREHARRLLADG
TLIRAGDTASAVEAELRVHRGEAAAAVMFPERLAADLAAGRPAEVQVLIDGADPNRSTVAADAVARYFGGVGERLAREAL
AARGATPPGQLALVPRLFYNPGLDSPPYMVPGIAALLLVVVTTIVSAMGLAREREMGTLEQVLVTPIRPAVLLAGKIAPY
VIIGFVNLALLVGVASLIFGVPIRGPLPVLALGTLLYLLTTLGVGLFISTISKNQQQSFLGGFLFLVPALLLSGVMTPVA
AMPGWLRAITFVNPVRHFATVMRGSLLRGAGLADLAIPLTALAVIGSAIFVLSALRFRKTLS

Specific function: Unknown

COG id: COG0842

COG function: function code V; ABC-type multidrug transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1787010, Length=359, Percent_Identity=30.9192200557103, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI48994943, Length=369, Percent_Identity=33.0623306233062, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1787011, Length=345, Percent_Identity=31.0144927536232, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI226510979, Length=367, Percent_Identity=28.8828337874659, Blast_Score=121, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24650853, Length=416, Percent_Identity=23.7980769230769, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24650855, Length=418, Percent_Identity=23.6842105263158, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000412
- InterPro:   IPR013526
- InterPro:   IPR013525 [H]

Pfam domain/function: PF01061 ABC2_membrane [H]

EC number: NA

Molecular weight: Translated: 40801; Mature: 40670

Theoretical pI: Translated: 11.68; Mature: 11.68

Prosite motif: PS51012 ABC_TM2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPRRPRPSARVQFLAVFRKEVRQTARDKRMMAVLVIAPLLQTVVFGFAANFDVDRVRTV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
VLDRDRTDVSREHARRLLADGTLIRAGDTASAVEAELRVHRGEAAAAVMFPERLAADLAA
HHCCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
GRPAEVQVLIDGADPNRSTVAADAVARYFGGVGERLAREALAARGATPPGQLALVPRLFY
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHH
NPGLDSPPYMVPGIAALLLVVVTTIVSAMGLAREREMGTLEQVLVTPIRPAVLLAGKIAP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
YVIIGFVNLALLVGVASLIFGVPIRGPLPVLALGTLLYLLTTLGVGLFISTISKNQQQSF
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LGGFLFLVPALLLSGVMTPVAAMPGWLRAITFVNPVRHFATVMRGSLLRGAGLADLAIPL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
TALAVIGSAIFVLSALRFRKTLS
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPRRPRPSARVQFLAVFRKEVRQTARDKRMMAVLVIAPLLQTVVFGFAANFDVDRVRTV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
VLDRDRTDVSREHARRLLADGTLIRAGDTASAVEAELRVHRGEAAAAVMFPERLAADLAA
HHCCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
GRPAEVQVLIDGADPNRSTVAADAVARYFGGVGERLAREALAARGATPPGQLALVPRLFY
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHH
NPGLDSPPYMVPGIAALLLVVVTTIVSAMGLAREREMGTLEQVLVTPIRPAVLLAGKIAP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
YVIIGFVNLALLVGVASLIFGVPIRGPLPVLALGTLLYLLTTLGVGLFISTISKNQQQSF
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LGGFLFLVPALLLSGVMTPVAAMPGWLRAITFVNPVRHFATVMRGSLLRGAGLADLAIPL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
TALAVIGSAIFVLSALRFRKTLS
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]