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The map label for this gene is aroG [H]

Identifier: 220918246

GI number: 220918246

Start: 3479476

End: 3480570

Strand: Direct

Name: aroG [H]

Synonym: A2cp1_3149

Alternate gene names: 220918246

Gene position: 3479476-3480570 (Clockwise)

Preceding gene: 220918245

Following gene: 220918247

Centisome position: 69.18

GC content: 71.23

Gene sequence:

>1095_bases
ATGCCCTACAGAACGGACGACCTCCGCATCCGCGGGATCAAGGAGCTCGCCCCGCCGTCGCACCTGATCCGCGAGTTCCC
CTGCACCGAGAAGGCGTCGGCCGTCGTCCACGGCGCGCGCCAGGCCATCCACCGGATCCTCCACGGGATGGACGACCGCC
TGGTCGTGGTGGTGGGCCCCTGCTCGATCCACGACACGAAGGCGGCGAAGGAGTACGCCGCGCGGCTCCTGGACGAGCGC
GTGCGCCACGCGGAGGACCTCGAGGTCGTGATGCGCGTCTACTTCGAGAAGCCGCGCACCACGGTCGGCTGGAAGGGGCT
CATCAACGACCCGGGCCTCGACAAGACCTACGACATCAACCGCGGCCTGCGCGTCGCGCGCGAGCTCCTGCTGGACGTGG
GCGAGATCGGCGTGCCGGCCGGCTGCGAGTACCTCGACATGATCACGCCGCAGTACATCGCGGACCTGGTCTCCTGGGGC
GCGATCGGCGCGCGCACCACCGAGAGCCAGGTGCACCGCGAGCTCGCCTCCGGCCTCTCCTGCCCGGTCGGCTTCAAGAA
CGGCACCGACGGCAACGTCGCCATCGCGATCGACGCCATCAAGGCGGCGCAGCAGCCGCACCACTTCCTGTCGGTGACGA
AGGGCGGCCACTCGGCCATCGTCTCCACCAACGGGAACGAGGACTGCCACATCATCCTGCGCGGCGGGCGCGCCCCGAAC
TACGACGCCGCCAGCGTGGACGCCGCCTGCCAGGAGATCGGCAAGGCCGGCCTGGCGCAGCGGCTCATGATCGACGCGAG
CCACGCGAACAGCCAGAAGAAGCCGGAGAACCAGATCCCGGTCTGCGCGAACGTGGCGGCGCAGGTGGCCGGTGGGGAGG
TCCGCGTGGTGGGCGTCATGATCGAGAGCCACCTCGTGGCCGGGCGGCAGGACCTGAAGGTCGGCAAGCCGCTCACCTAC
GGGCAGAGCGTCACCGACGGCTGCCTGGGCTGGGAGGACACGGTGCGCGTGCTGGACGGCCTCGCGGCCGCGGTGCGCGA
CCGCCGGGTGAAGGAGGCGGGCTTCAACGGCGGCGCCGAGGCCGCGCCCGCCTGA

Upstream 100 bases:

>100_bases
CTTCTGACGGGGCTGCGCCCCGCGGGCGCGGCCGGCGCAGCCCGGGCGGCACACCCGCCCGGGCTGCGCTAGGATGTGCG
TTCCGGCCACCGAGGAACGC

Downstream 100 bases:

>100_bases
TCCCCCGCGCGGCGGAGGCGCGCGATCCTCCATGCGCGGCGACGGCCGAAAGGCTATGGTGCCGCGCTTGAGCCCGACCT
TTGCAGACCTGAACCTCTCC

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MPYRTDDLRIRGIKELAPPSHLIREFPCTEKASAVVHGARQAIHRILHGMDDRLVVVVGPCSIHDTKAAKEYAARLLDER
VRHAEDLEVVMRVYFEKPRTTVGWKGLINDPGLDKTYDINRGLRVARELLLDVGEIGVPAGCEYLDMITPQYIADLVSWG
AIGARTTESQVHRELASGLSCPVGFKNGTDGNVAIAIDAIKAAQQPHHFLSVTKGGHSAIVSTNGNEDCHIILRGGRAPN
YDAASVDAACQEIGKAGLAQRLMIDASHANSQKKPENQIPVCANVAAQVAGGEVRVVGVMIESHLVAGRQDLKVGKPLTY
GQSVTDGCLGWEDTVRVLDGLAAAVRDRRVKEAGFNGGAEAAPA

Sequences:

>Translated_364_residues
MPYRTDDLRIRGIKELAPPSHLIREFPCTEKASAVVHGARQAIHRILHGMDDRLVVVVGPCSIHDTKAAKEYAARLLDER
VRHAEDLEVVMRVYFEKPRTTVGWKGLINDPGLDKTYDINRGLRVARELLLDVGEIGVPAGCEYLDMITPQYIADLVSWG
AIGARTTESQVHRELASGLSCPVGFKNGTDGNVAIAIDAIKAAQQPHHFLSVTKGGHSAIVSTNGNEDCHIILRGGRAPN
YDAASVDAACQEIGKAGLAQRLMIDASHANSQKKPENQIPVCANVAAQVAGGEVRVVGVMIESHLVAGRQDLKVGKPLTY
GQSVTDGCLGWEDTVRVLDGLAAAVRDRRVKEAGFNGGAEAAPA
>Mature_363_residues
PYRTDDLRIRGIKELAPPSHLIREFPCTEKASAVVHGARQAIHRILHGMDDRLVVVVGPCSIHDTKAAKEYAARLLDERV
RHAEDLEVVMRVYFEKPRTTVGWKGLINDPGLDKTYDINRGLRVARELLLDVGEIGVPAGCEYLDMITPQYIADLVSWGA
IGARTTESQVHRELASGLSCPVGFKNGTDGNVAIAIDAIKAAQQPHHFLSVTKGGHSAIVSTNGNEDCHIILRGGRAPNY
DAASVDAACQEIGKAGLAQRLMIDASHANSQKKPENQIPVCANVAAQVAGGEVRVVGVMIESHLVAGRQDLKVGKPLTYG
QSVTDGCLGWEDTVRVLDGLAAAVRDRRVKEAGFNGGAEAAPA

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786969, Length=349, Percent_Identity=65.6160458452722, Blast_Score=478, Evalue=1e-136,
Organism=Escherichia coli, GI1787996, Length=345, Percent_Identity=53.9130434782609, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI1788953, Length=334, Percent_Identity=49.1017964071856, Blast_Score=330, Evalue=6e-92,
Organism=Saccharomyces cerevisiae, GI6320240, Length=354, Percent_Identity=52.2598870056497, Blast_Score=358, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6319726, Length=347, Percent_Identity=54.178674351585, Blast_Score=353, Evalue=3e-98,

Paralogues:

None

Copy number: 600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 39077; Mature: 38946

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYRTDDLRIRGIKELAPPSHLIREFPCTEKASAVVHGARQAIHRILHGMDDRLVVVVGP
CCCCCCCCEECCHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
CSIHDTKAAKEYAARLLDERVRHAEDLEVVMRVYFEKPRTTVGWKGLINDPGLDKTYDIN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEECH
RGLRVARELLLDVGEIGVPAGCEYLDMITPQYIADLVSWGAIGARTTESQVHRELASGLS
HHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCC
CPVGFKNGTDGNVAIAIDAIKAAQQPHHFLSVTKGGHSAIVSTNGNEDCHIILRGGRAPN
CCCCCCCCCCCCEEEEEEHHHHHCCCCCEEEEECCCCEEEEECCCCCCEEEEEECCCCCC
YDAASVDAACQEIGKAGLAQRLMIDASHANSQKKPENQIPVCANVAAQVAGGEVRVVGVM
CCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEE
IESHLVAGRQDLKVGKPLTYGQSVTDGCLGWEDTVRVLDGLAAAVRDRRVKEAGFNGGAE
EHHHHHCCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AAPA
CCCC
>Mature Secondary Structure 
PYRTDDLRIRGIKELAPPSHLIREFPCTEKASAVVHGARQAIHRILHGMDDRLVVVVGP
CCCCCCCEECCHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
CSIHDTKAAKEYAARLLDERVRHAEDLEVVMRVYFEKPRTTVGWKGLINDPGLDKTYDIN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEECH
RGLRVARELLLDVGEIGVPAGCEYLDMITPQYIADLVSWGAIGARTTESQVHRELASGLS
HHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCC
CPVGFKNGTDGNVAIAIDAIKAAQQPHHFLSVTKGGHSAIVSTNGNEDCHIILRGGRAPN
CCCCCCCCCCCCEEEEEEHHHHHCCCCCEEEEECCCCEEEEECCCCCCEEEEEECCCCCC
YDAASVDAACQEIGKAGLAQRLMIDASHANSQKKPENQIPVCANVAAQVAGGEVRVVGVM
CCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEE
IESHLVAGRQDLKVGKPLTYGQSVTDGCLGWEDTVRVLDGLAAAVRDRRVKEAGFNGGAE
EHHHHHCCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AAPA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]