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The map label for this gene is hsaD [H]

Identifier: 220918229

GI number: 220918229

Start: 3460015

End: 3461049

Strand: Direct

Name: hsaD [H]

Synonym: A2cp1_3132

Alternate gene names: 220918229

Gene position: 3460015-3461049 (Clockwise)

Preceding gene: 220918226

Following gene: 220918230

Centisome position: 68.8

GC content: 74.11

Gene sequence:

>1035_bases
ATGCCCTCGCCACGCCGCAAGACCCTCCGCTGCCTCCTGGCGCCGCTCGCCGCGCTCGCCCTCGCCTGCGCCGGGGCGCC
GGCCCGCGCGCCCGCCGCGCAGGTCCCGCCCGGCGCCATCGACCCGGAGGCGACCGGGTTCGAGTACCCGCTCCCGGTCT
CGTACTTCGAGCTCGACAGCCAGCGCCAGCCGCTGCGCATGGCGTACGTCGACGCGCCCGCCGCCGCGCCGAACGGCCGG
ACGGTGCTGCTCCTCCACGGCAAGAACTTCCACGCCGGCACCTGGGCCGACACCATCGCCGCGCTGAACCGGGCCGGGTT
CCGCGTGATCGCGCCCGACCAGATCGGCTTCGGCAAGTCCAGCAAGCCGGAGCGCTACCAGTTCTCGTTCGTGCAGCTCG
CCGCCAACACCCGGGCGCTGCTCGCCTCCCTCGGCATCGCGCGCACCGCCGTGGTCGGGCACTCGATGGGAGGGATGCTC
GCGGTGCGCTACGCGCTCGAGTACCCGGACGCCACCGAGCGCCTCCTGCTCGTGAACCCGATCGGCCTCGAGGACTACGC
CGCGTTCCTGCCGCCGCGCACGGTGGACCAGTGGTACGCGCAGGAGCTGAAGCAGACGCCGGACTCGGTCCGGGAGTACC
AGCGGAAGGCGTACTACGACGGCGCCTGGAGGCCGGAGTACGAGGCCCACACGCGGCTGCTCGCGGGGTGGACGCTGCAC
CCGGGCTGGCCGCGGATCGCGTGGGACAGCGCGCTCACCTACGACATGATCGTCACGCAGCCGGTGGTGCACGAGCTGGA
GCGCCTGGCGGTGCCCACGCGCCTCGTGATCGGCCTTCGCGACCGCACCGCCATCGGCCGGCCGCTCGCGCCCGCCGGCG
TGCGCGAGTCGATGGGGGACTACACGCGCCTCGGGAAGGCGGCGCAGCGGCGGATCCCCGGCGCCGACCTGGTGGAGCTC
CCCGGCATCGGCCACGTGCCCCAGGTCGAGGCCTTCCCGGCCTTCGAGAAGGCGCTGCTCGACTTCCTCCGCTGA

Upstream 100 bases:

>100_bases
TCCCGCGTCCGCGGGCGGTCCACCGTGCGCGACCGCGGCAGCGCCCTTACACCCCTGCCCGCGCCGCGGGCCGCGGCGCC
CCACCCCGGAGCCCGCACCC

Downstream 100 bases:

>100_bases
GACCGAGCCGGGCCGATCCCCGGGCGCCGCGCCGTCCACCGGGCACACCGCCGGGGCCGGCGCCGGAAGCGCTGCGCGCG
AAGGACGTCGGTCCTGCGCG

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; HOPDA hydrolase; Meta-cleavage product hydrolase; MCP hydrolase [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MPSPRRKTLRCLLAPLAALALACAGAPARAPAAQVPPGAIDPEATGFEYPLPVSYFELDSQRQPLRMAYVDAPAAAPNGR
TVLLLHGKNFHAGTWADTIAALNRAGFRVIAPDQIGFGKSSKPERYQFSFVQLAANTRALLASLGIARTAVVGHSMGGML
AVRYALEYPDATERLLLVNPIGLEDYAAFLPPRTVDQWYAQELKQTPDSVREYQRKAYYDGAWRPEYEAHTRLLAGWTLH
PGWPRIAWDSALTYDMIVTQPVVHELERLAVPTRLVIGLRDRTAIGRPLAPAGVRESMGDYTRLGKAAQRRIPGADLVEL
PGIGHVPQVEAFPAFEKALLDFLR

Sequences:

>Translated_344_residues
MPSPRRKTLRCLLAPLAALALACAGAPARAPAAQVPPGAIDPEATGFEYPLPVSYFELDSQRQPLRMAYVDAPAAAPNGR
TVLLLHGKNFHAGTWADTIAALNRAGFRVIAPDQIGFGKSSKPERYQFSFVQLAANTRALLASLGIARTAVVGHSMGGML
AVRYALEYPDATERLLLVNPIGLEDYAAFLPPRTVDQWYAQELKQTPDSVREYQRKAYYDGAWRPEYEAHTRLLAGWTLH
PGWPRIAWDSALTYDMIVTQPVVHELERLAVPTRLVIGLRDRTAIGRPLAPAGVRESMGDYTRLGKAAQRRIPGADLVEL
PGIGHVPQVEAFPAFEKALLDFLR
>Mature_343_residues
PSPRRKTLRCLLAPLAALALACAGAPARAPAAQVPPGAIDPEATGFEYPLPVSYFELDSQRQPLRMAYVDAPAAAPNGRT
VLLLHGKNFHAGTWADTIAALNRAGFRVIAPDQIGFGKSSKPERYQFSFVQLAANTRALLASLGIARTAVVGHSMGGMLA
VRYALEYPDATERLLLVNPIGLEDYAAFLPPRTVDQWYAQELKQTPDSVREYQRKAYYDGAWRPEYEAHTRLLAGWTLHP
GWPRIAWDSALTYDMIVTQPVVHELERLAVPTRLVIGLRDRTAIGRPLAPAGVRESMGDYTRLGKAAQRRIPGADLVELP
GIGHVPQVEAFPAFEKALLDFLR

Specific function: Catalyzes the hydrolysis of a carbon-carbon bond in 4,5- 9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oic acid (4,9-DSHA) to yield 9,17-dioxo-1,2,3,4,10,19- hexanorandrostan-5-oic acid (DOHNAA) and 2-hydroxy-hexa-2,4- dienoic acid (HHD). Is

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HsaD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.7.1.8 [H]

Molecular weight: Translated: 37752; Mature: 37621

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSPRRKTLRCLLAPLAALALACAGAPARAPAAQVPPGAIDPEATGFEYPLPVSYFELDS
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEECCC
QRQPLRMAYVDAPAAAPNGRTVLLLHGKNFHAGTWADTIAALNRAGFRVIAPDQIGFGKS
CCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCC
SKPERYQFSFVQLAANTRALLASLGIARTAVVGHSMGGMLAVRYALEYPDATERLLLVNP
CCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCCCCCEEEECC
IGLEDYAAFLPPRTVDQWYAQELKQTPDSVREYQRKAYYDGAWRPEYEAHTRLLAGWTLH
CCHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHEEEECCEEC
PGWPRIAWDSALTYDMIVTQPVVHELERLAVPTRLVIGLRDRTAIGRPLAPAGVRESMGD
CCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCHHEEEECCCCCCCCCCCCCCHHHHHHHH
YTRLGKAAQRRIPGADLVELPGIGHVPQVEAFPAFEKALLDFLR
HHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHC
>Mature Secondary Structure 
PSPRRKTLRCLLAPLAALALACAGAPARAPAAQVPPGAIDPEATGFEYPLPVSYFELDS
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEECCC
QRQPLRMAYVDAPAAAPNGRTVLLLHGKNFHAGTWADTIAALNRAGFRVIAPDQIGFGKS
CCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCC
SKPERYQFSFVQLAANTRALLASLGIARTAVVGHSMGGMLAVRYALEYPDATERLLLVNP
CCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCCCCCEEEECC
IGLEDYAAFLPPRTVDQWYAQELKQTPDSVREYQRKAYYDGAWRPEYEAHTRLLAGWTLH
CCHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHEEEECCEEC
PGWPRIAWDSALTYDMIVTQPVVHELERLAVPTRLVIGLRDRTAIGRPLAPAGVRESMGD
CCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCHHEEEECCCCCCCCCCCCCCHHHHHHHH
YTRLGKAAQRRIPGADLVELPGIGHVPQVEAFPAFEKALLDFLR
HHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]