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The map label for this gene is amiC [H]

Identifier: 220918211

GI number: 220918211

Start: 3437207

End: 3438688

Strand: Direct

Name: amiC [H]

Synonym: A2cp1_3114

Alternate gene names: 220918211

Gene position: 3437207-3438688 (Clockwise)

Preceding gene: 220918210

Following gene: 220918212

Centisome position: 68.34

GC content: 78.61

Gene sequence:

>1482_bases
TTGGCCGCCCGATCCGACCTCCCCGCCCCGACCGATCCCTTCGCCGCGCTCGACGCCACCGCGCAGGCCGCGCTGGTGCG
CGAGGGCGACGCCACGCCGCTCGAGCTGGTGGACGCGGCGCTCGCCCGCCTCGACCGCCTCGGCGACCTCAACGTCGCCG
CCTCGGTCGATCCGGAGCGCGCCCGGCGGGCCGCCCGCGAGGTCCGCCGCGGCGCGCCGCTCGCCGGCGTGCCGTTCCTG
CTGAAGGACCTGCTCCCCTACCCTGGCCTGCCGCTCGGCTGCGGCTCGCGCCTCCTGGCCGGCCAGGCGTCGCCCCCGGC
GCCGGACCTCGCGCGCGCGTTCGACGACGCGGGGCTGGTCGTGCTGGGCAAGAGCACCACCTCCGAGTTCGGCCTGCTCG
GCACCACCGAGACCCTGGCGTGCGGCGCCACCCTCAACCCCTGGGATCCGGCGCGCTCGCCGGCCGGTTCGTCCGGCGGC
TCGGCCGCCGCGGTGGCGGCGGGCATCGTCCCGGTGGCGCACGCGTCCGACGGCGGCGGCTCGATCCGCATCCCGGCCTC
GGTGTGCGGCGTTGTGGGGCTGAAGCCCAGCCGCGGGCGGCAGCGCGACGTCGGCATGCCGCTCGACACGCCGCTCGCTG
CGCTGGTGGTGGATCACTGCGTGAGCCGCTCCGTCCGGGACAGCGCGGCGCTGCTCGGGCTGACGCAGCGGCGCGACGCC
ACCGCGCCGTGGCCCCCGCTCGGCCCCGAGGCGCTCTCGCCCTCGGCGCACCCGCGGCGGCTCCGGATCGGCGTGTACGC
GCGGACCGGCTTCGACCGCGCGCCCGCCCCCGAGATCCGCGCCGGCCTGGACGCGGCGCGCCGGCTGTGCGAGGGGCTCG
GCCACGAAACGATCGAGGTCGCCGGGCCACGCTTCGACGCGGCCGCCACCCGCGACGCGATCTTCCTCCTGTTCGGCGCG
ACGCTCGGCCCGCTGGTGGCGCAGGTCCGGGGCGCCGCGGGGGAGGCCGCGCTCCCCGCCCTGCTCGAGCCGTTCACGCT
CGAGCTGGTGGAGCGCGCGGAGGCCGCCGGTCCGGCGGCGCTCGCGGCGGCGAGAGCCGCGCTCGACGTCGCCGCCCGCG
AGGGCCTGGCCTTCCTCGACGGGCTCGACGCCGCGCTCAGCCCCACCACCGCCGTGCTCCCGTTCCCGCTCGATACGCTC
TCGCCGCGCCACCCCGTCGATCGGAACCTCGCCTTCACCGAGGACCTCGCCGGCTACACGGCCATCCACTCGATCACCGG
CGCGCCCGCGATGTCCGTCCCCCTGCACTGGACCGCCGGCGGCCTGCCGGTGGGGATGCAGCTCGTGGCACGCCCCGGGG
ACGAGGCCCTGCTGCTGCAGCTCGCGTATGCGCTGGAGGCGGCGGCGCCCTGGAAGGATCGGTGGCCGCCGCGCTCCGCC
GTGGCGGTCGCCGCCGGGGAGGGCCCGTGGCGCAGCGCCTGA

Upstream 100 bases:

>100_bases
GCGCTGGGCGTGCCCGAGCGGCGCTGAGCCGGCGGTTGCGCGGCGGCTGAAACGCGAATACGGTATTCGCGTTTCGGCAC
CCTGCCCCAGGAGCCCGCCC

Downstream 100 bases:

>100_bases
AGGAGGACGTGCGCGCCCGCCTGGTGGACGCGGCGCTGTCCGAGTTCGTCCGGCAGGGCTGGCGCGGGGCGCGGCTGGTG
GACATCGCCGCCGCGGCGGG

Product: Amidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 492

Protein sequence:

>493_residues
MAARSDLPAPTDPFAALDATAQAALVREGDATPLELVDAALARLDRLGDLNVAASVDPERARRAAREVRRGAPLAGVPFL
LKDLLPYPGLPLGCGSRLLAGQASPPAPDLARAFDDAGLVVLGKSTTSEFGLLGTTETLACGATLNPWDPARSPAGSSGG
SAAAVAAGIVPVAHASDGGGSIRIPASVCGVVGLKPSRGRQRDVGMPLDTPLAALVVDHCVSRSVRDSAALLGLTQRRDA
TAPWPPLGPEALSPSAHPRRLRIGVYARTGFDRAPAPEIRAGLDAARRLCEGLGHETIEVAGPRFDAAATRDAIFLLFGA
TLGPLVAQVRGAAGEAALPALLEPFTLELVERAEAAGPAALAAARAALDVAAREGLAFLDGLDAALSPTTAVLPFPLDTL
SPRHPVDRNLAFTEDLAGYTAIHSITGAPAMSVPLHWTAGGLPVGMQLVARPGDEALLLQLAYALEAAAPWKDRWPPRSA
VAVAAGEGPWRSA

Sequences:

>Translated_493_residues
MAARSDLPAPTDPFAALDATAQAALVREGDATPLELVDAALARLDRLGDLNVAASVDPERARRAAREVRRGAPLAGVPFL
LKDLLPYPGLPLGCGSRLLAGQASPPAPDLARAFDDAGLVVLGKSTTSEFGLLGTTETLACGATLNPWDPARSPAGSSGG
SAAAVAAGIVPVAHASDGGGSIRIPASVCGVVGLKPSRGRQRDVGMPLDTPLAALVVDHCVSRSVRDSAALLGLTQRRDA
TAPWPPLGPEALSPSAHPRRLRIGVYARTGFDRAPAPEIRAGLDAARRLCEGLGHETIEVAGPRFDAAATRDAIFLLFGA
TLGPLVAQVRGAAGEAALPALLEPFTLELVERAEAAGPAALAAARAALDVAAREGLAFLDGLDAALSPTTAVLPFPLDTL
SPRHPVDRNLAFTEDLAGYTAIHSITGAPAMSVPLHWTAGGLPVGMQLVARPGDEALLLQLAYALEAAAPWKDRWPPRSA
VAVAAGEGPWRSA
>Mature_492_residues
AARSDLPAPTDPFAALDATAQAALVREGDATPLELVDAALARLDRLGDLNVAASVDPERARRAAREVRRGAPLAGVPFLL
KDLLPYPGLPLGCGSRLLAGQASPPAPDLARAFDDAGLVVLGKSTTSEFGLLGTTETLACGATLNPWDPARSPAGSSGGS
AAAVAAGIVPVAHASDGGGSIRIPASVCGVVGLKPSRGRQRDVGMPLDTPLAALVVDHCVSRSVRDSAALLGLTQRRDAT
APWPPLGPEALSPSAHPRRLRIGVYARTGFDRAPAPEIRAGLDAARRLCEGLGHETIEVAGPRFDAAATRDAIFLLFGAT
LGPLVAQVRGAAGEAALPALLEPFTLELVERAEAAGPAALAAARAALDVAAREGLAFLDGLDAALSPTTAVLPFPLDTLS
PRHPVDRNLAFTEDLAGYTAIHSITGAPAMSVPLHWTAGGLPVGMQLVARPGDEALLLQLAYALEAAAPWKDRWPPRSAV
AVAAGEGPWRSA

Specific function: Unknown

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=502, Percent_Identity=25.4980079681275, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI195972892, Length=214, Percent_Identity=27.5700934579439, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17556264, Length=297, Percent_Identity=28.956228956229, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17537465, Length=206, Percent_Identity=28.1553398058252, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538252, Length=531, Percent_Identity=22.9755178907721, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71990152, Length=186, Percent_Identity=34.9462365591398, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17556276, Length=256, Percent_Identity=28.90625, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17556278, Length=256, Percent_Identity=28.90625, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6323950, Length=470, Percent_Identity=24.0425531914894, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21356731, Length=487, Percent_Identity=27.1047227926078, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24648113, Length=508, Percent_Identity=27.9527559055118, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24644968, Length=191, Percent_Identity=33.5078534031414, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI45550774, Length=509, Percent_Identity=24.75442043222, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24648435, Length=509, Percent_Identity=24.75442043222, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24648437, Length=509, Percent_Identity=24.75442043222, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI161078093, Length=431, Percent_Identity=25.0580046403712, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24648441, Length=426, Percent_Identity=25.1173708920188, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24648439, Length=426, Percent_Identity=25.1173708920188, Blast_Score=76, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: =3.5.1.4 [H]

Molecular weight: Translated: 50464; Mature: 50333

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARSDLPAPTDPFAALDATAQAALVREGDATPLELVDAALARLDRLGDLNVAASVDPER
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCHHH
ARRAAREVRRGAPLAGVPFLLKDLLPYPGLPLGCGSRLLAGQASPPAPDLARAFDDAGLV
HHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHCCCCEE
VLGKSTTSEFGLLGTTETLACGATLNPWDPARSPAGSSGGSAAAVAAGIVPVAHASDGGG
EEECCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCEEEEECCCCCC
SIRIPASVCGVVGLKPSRGRQRDVGMPLDTPLAALVVDHCVSRSVRDSAALLGLTQRRDA
EEEECHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCC
TAPWPPLGPEALSPSAHPRRLRIGVYARTGFDRAPAPEIRAGLDAARRLCEGLGHETIEV
CCCCCCCCHHHCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEE
AGPRFDAAATRDAIFLLFGATLGPLVAQVRGAAGEAALPALLEPFTLELVERAEAAGPAA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHH
LAAARAALDVAAREGLAFLDGLDAALSPTTAVLPFPLDTLSPRHPVDRNLAFTEDLAGYT
HHHHHHHHHHHHHCCHHHHHCCCHHCCCCCEEECCCHHCCCCCCCCCCCCCHHHHHHHHH
AIHSITGAPAMSVPLHWTAGGLPVGMQLVARPGDEALLLQLAYALEAAAPWKDRWPPRSA
HHHHHCCCCCEECCEEEECCCCCCCHHEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCE
VAVAAGEGPWRSA
EEEEECCCCCCCC
>Mature Secondary Structure 
AARSDLPAPTDPFAALDATAQAALVREGDATPLELVDAALARLDRLGDLNVAASVDPER
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCHHH
ARRAAREVRRGAPLAGVPFLLKDLLPYPGLPLGCGSRLLAGQASPPAPDLARAFDDAGLV
HHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHCCCCEE
VLGKSTTSEFGLLGTTETLACGATLNPWDPARSPAGSSGGSAAAVAAGIVPVAHASDGGG
EEECCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCEEEEECCCCCC
SIRIPASVCGVVGLKPSRGRQRDVGMPLDTPLAALVVDHCVSRSVRDSAALLGLTQRRDA
EEEECHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCC
TAPWPPLGPEALSPSAHPRRLRIGVYARTGFDRAPAPEIRAGLDAARRLCEGLGHETIEV
CCCCCCCCHHHCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEE
AGPRFDAAATRDAIFLLFGATLGPLVAQVRGAAGEAALPALLEPFTLELVERAEAAGPAA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHH
LAAARAALDVAAREGLAFLDGLDAALSPTTAVLPFPLDTLSPRHPVDRNLAFTEDLAGYT
HHHHHHHHHHHHHCCHHHHHCCCHHCCCCCEEECCCHHCCCCCCCCCCCCCHHHHHHHHH
AIHSITGAPAMSVPLHWTAGGLPVGMQLVARPGDEALLLQLAYALEAAAPWKDRWPPRSA
HHHHHCCCCCEECCEEEECCCCCCCHHEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCE
VAVAAGEGPWRSA
EEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]