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The map label for this gene is arlR [H]

Identifier: 220918203

GI number: 220918203

Start: 3431780

End: 3432484

Strand: Direct

Name: arlR [H]

Synonym: A2cp1_3106

Alternate gene names: 220918203

Gene position: 3431780-3432484 (Clockwise)

Preceding gene: 220918202

Following gene: 220918204

Centisome position: 68.24

GC content: 76.74

Gene sequence:

>705_bases
ATGACCGCCGCGACCCCGCTCCTGGCGCTGCTCGTCGAGGACGACCTCCGCCTGGCCGCGTTCACCCGCGAGTATCTCGA
GGGGCACGGCGTGGCGGTGGTCCACGCGACCGACGGGCGACGCGGCCTCGACGAGGCGCTCGGCGGCCGCTTCGACGTGG
TGCTGCTCGACCTCATGCTGCCGGGCAAGGACGGCCTGGAGGTCTGCCGCGAGCTCCGGTCGCGCTCCGACGTCCCCGTC
ATCGTCCTCACCGCGCGCGGCGAGGAGGCGGACCGCGTGATGGGCCTCGAGCTCGGCGCCGACGACTACCTGGCGAAGCC
GTTCTCGCCGCGCGAGCTGCTCGCGCGGATCCGCGCCGTGGTCCGGCGCGCCACCGGCCGCGCCGGGCCGCCGCGCGAGG
TGGTGCGGGTCGGCGGGCTGGTGGTGGACCCGGCGGCGCGCCGGGTGACGCTGGACGGGCGCGAGGTGGCGCTCACCGGG
TACGAGTTCGCGCTGCTGCACGCGCTGGCGCGCCGCGCGGGCCGGGTGCTCGCCCGGGAGCAGCTCATGGAGCTGGCCGG
CGGCAGCGCGGAGGAGGCGTTCGACCGCTCCGTGGACGTGCACGTCTCCCGGCTGCGGCAGAAGCTCGGCGACGATCCCC
GGCGGCCCCGCCTCATCAAGACGGTCCGCGGCGCCGGGTACCTGCTCGCCGGGGAACCGGGATGA

Upstream 100 bases:

>100_bases
GCGCGAGAAGCTCACGCGCAAGATCGAGCGCCTGCATCGCTAGCCCGTGCCCCGGAGCGGACCCGCGGTGACGGCGCGAG
CCCCACGCTATGATGCCCCG

Downstream 100 bases:

>100_bases
GCCGCCGCGCGCACGGGCCGCTCTTCTGGCGCGTCTACCTGCACGGCGTGCTCCTGCTGCTGGTGGTGGCGATCGCGGTC
GGCGCGGTCGGCTTCGCGCT

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MTAATPLLALLVEDDLRLAAFTREYLEGHGVAVVHATDGRRGLDEALGGRFDVVLLDLMLPGKDGLEVCRELRSRSDVPV
IVLTARGEEADRVMGLELGADDYLAKPFSPRELLARIRAVVRRATGRAGPPREVVRVGGLVVDPAARRVTLDGREVALTG
YEFALLHALARRAGRVLAREQLMELAGGSAEEAFDRSVDVHVSRLRQKLGDDPRRPRLIKTVRGAGYLLAGEPG

Sequences:

>Translated_234_residues
MTAATPLLALLVEDDLRLAAFTREYLEGHGVAVVHATDGRRGLDEALGGRFDVVLLDLMLPGKDGLEVCRELRSRSDVPV
IVLTARGEEADRVMGLELGADDYLAKPFSPRELLARIRAVVRRATGRAGPPREVVRVGGLVVDPAARRVTLDGREVALTG
YEFALLHALARRAGRVLAREQLMELAGGSAEEAFDRSVDVHVSRLRQKLGDDPRRPRLIKTVRGAGYLLAGEPG
>Mature_233_residues
TAATPLLALLVEDDLRLAAFTREYLEGHGVAVVHATDGRRGLDEALGGRFDVVLLDLMLPGKDGLEVCRELRSRSDVPVI
VLTARGEEADRVMGLELGADDYLAKPFSPRELLARIRAVVRRATGRAGPPREVVRVGGLVVDPAARRVTLDGREVALTGY
EFALLHALARRAGRVLAREQLMELAGGSAEEAFDRSVDVHVSRLRQKLGDDPRRPRLIKTVRGAGYLLAGEPG

Specific function: Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion, autolysis, multidrug resistance and virulence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=45.575221238938, Blast_Score=181, Evalue=4e-47,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=43.2314410480349, Blast_Score=167, Evalue=4e-43,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=42.8571428571429, Blast_Score=162, Evalue=1e-41,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=41.9642857142857, Blast_Score=157, Evalue=5e-40,
Organism=Escherichia coli, GI1786911, Length=218, Percent_Identity=43.5779816513761, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=38.4615384615385, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=43.4389140271493, Blast_Score=153, Evalue=8e-39,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=40.3669724770642, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=40.7239819004525, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=36.9565217391304, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=35.3191489361702, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=37.5, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=34.6153846153846, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=34.5291479820628, Blast_Score=119, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25398; Mature: 25267

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAATPLLALLVEDDLRLAAFTREYLEGHGVAVVHATDGRRGLDEALGGRFDVVLLDLML
CCCHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHCCCHHEEEEEECC
PGKDGLEVCRELRSRSDVPVIVLTARGEEADRVMGLELGADDYLAKPFSPRELLARIRAV
CCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHEEEEEECCCHHHCCCCCHHHHHHHHHHH
VRRATGRAGPPREVVRVGGLVVDPAARRVTLDGREVALTGYEFALLHALARRAGRVLARE
HHHHCCCCCCHHHHHHHCCEEECCCCCEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHH
QLMELAGGSAEEAFDRSVDVHVSRLRQKLGDDPRRPRLIKTVRGAGYLLAGEPG
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEECCCC
>Mature Secondary Structure 
TAATPLLALLVEDDLRLAAFTREYLEGHGVAVVHATDGRRGLDEALGGRFDVVLLDLML
CCHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHCCCHHEEEEEECC
PGKDGLEVCRELRSRSDVPVIVLTARGEEADRVMGLELGADDYLAKPFSPRELLARIRAV
CCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHEEEEEECCCHHHCCCCCHHHHHHHHHHH
VRRATGRAGPPREVVRVGGLVVDPAARRVTLDGREVALTGYEFALLHALARRAGRVLARE
HHHHCCCCCCHHHHHHHCCEEECCCCCEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHH
QLMELAGGSAEEAFDRSVDVHVSRLRQKLGDDPRRPRLIKTVRGAGYLLAGEPG
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA