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The map label for this gene is htpX [H]

Identifier: 220918122

GI number: 220918122

Start: 3350166

End: 3351089

Strand: Direct

Name: htpX [H]

Synonym: A2cp1_3025

Alternate gene names: 220918122

Gene position: 3350166-3351089 (Clockwise)

Preceding gene: 220918118

Following gene: 220918126

Centisome position: 66.61

GC content: 73.16

Gene sequence:

>924_bases
ATGTCCTGGAGCGAGGCGGCCCAGCCGCGCGGCATGTCCCCGAAGGCCGGCGTGGGCCGGAACTACGCCAAGACCGCCAT
GCTGATGGCGCTGCTCATCGCGCTGCTCGCGATCGGCGGCAACGTGGTCGGCGGCATGCAGGGGATGCTACTCTTCGGCG
GGCTCGGGCTCGTCTTCAACTTCGTCTCCTACTGGTTCTCCGACCGGCTCGCGCTCATGGCGCACCGCGCGCGGCCGGTG
ACCCGCGAGGAGCTGCCGCAGGTGTACGAGATCGTCGAGCGGCTCACCCGCCGCGCCGGCATGCCCATGCCGCGCGTCTA
CGTCATTCCCTCCGAGACGCCGAACGCCTTCGCCACGGGCAGGAACCCGTCGCACGCGGCGGTCGCCGTCACCGAGGGGA
TCCTCCGCATCCTCGACCGGCGCCAGCTCGAGGGCGTGCTCGCGCACGAGCTCGCCCACGTGCGCAACCGCGACATCCTC
ATCTCCACCGTCGCCGCGGCGGTGGCCGGCCTCATCTCCACGCTCGGCTACGTGGTCCGCTGGGGCGCGCTGCTCGGCGG
CATGCGTCGCGAGGACGACCGCGGCGGCTCCGCGCTCGAGCTGCTGGCCTGGGCCATCCTGGCGCCGCTCGTGGCGCTCG
TGATCCAGCTCGCCGTGTCCCGCTCGCGCGAGTACGGCGCGGACGCGTCCGGCGCCGAGCTGGTGGGCGACCCGGAGCCG
CTCGCCGAGGCGCTGCTCGCGCTGGAGCGCGGCAACGAGGCCATCCCGTACCAGTACGGCGGCCCTGCCACCGCGCACCT
GTTCATCGTGAACCCGTTCCACGGGGCGGGCGCGAAGATGATGAGCCTGTTCTCGACCCACCCGCCGGTCGAGGAGCGCG
TGCGCCGGCTCCGCGAGATGCGGCGCGGCGTGCGGTACGCGTAG

Upstream 100 bases:

>100_bases
GGGATCCCGCGCGAGATCGCGGCGCCGCGTGCGCGCGAGCGCGCAGCCGGGCGGGCGGCCGGCGGATTGACGCGGCCCCT
CCGATGGTTACTCAAGCAGC

Downstream 100 bases:

>100_bases
GCGTCAGTAGGCGCAGGCGACCGCGCCGGTGCCCACGTCGAGCTGCCCCTGCAGCGTGCCGCCCTGGCCGTTCGAGACGA
TGAGGGTGTAGGTGCCGGGG

Product: peptidase M48 Ste24p

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSWSEAAQPRGMSPKAGVGRNYAKTAMLMALLIALLAIGGNVVGGMQGMLLFGGLGLVFNFVSYWFSDRLALMAHRARPV
TREELPQVYEIVERLTRRAGMPMPRVYVIPSETPNAFATGRNPSHAAVAVTEGILRILDRRQLEGVLAHELAHVRNRDIL
ISTVAAAVAGLISTLGYVVRWGALLGGMRREDDRGGSALELLAWAILAPLVALVIQLAVSRSREYGADASGAELVGDPEP
LAEALLALERGNEAIPYQYGGPATAHLFIVNPFHGAGAKMMSLFSTHPPVEERVRRLREMRRGVRYA

Sequences:

>Translated_307_residues
MSWSEAAQPRGMSPKAGVGRNYAKTAMLMALLIALLAIGGNVVGGMQGMLLFGGLGLVFNFVSYWFSDRLALMAHRARPV
TREELPQVYEIVERLTRRAGMPMPRVYVIPSETPNAFATGRNPSHAAVAVTEGILRILDRRQLEGVLAHELAHVRNRDIL
ISTVAAAVAGLISTLGYVVRWGALLGGMRREDDRGGSALELLAWAILAPLVALVIQLAVSRSREYGADASGAELVGDPEP
LAEALLALERGNEAIPYQYGGPATAHLFIVNPFHGAGAKMMSLFSTHPPVEERVRRLREMRRGVRYA
>Mature_306_residues
SWSEAAQPRGMSPKAGVGRNYAKTAMLMALLIALLAIGGNVVGGMQGMLLFGGLGLVFNFVSYWFSDRLALMAHRARPVT
REELPQVYEIVERLTRRAGMPMPRVYVIPSETPNAFATGRNPSHAAVAVTEGILRILDRRQLEGVLAHELAHVRNRDILI
STVAAAVAGLISTLGYVVRWGALLGGMRREDDRGGSALELLAWAILAPLVALVIQLAVSRSREYGADASGAELVGDPEPL
AEALLALERGNEAIPYQYGGPATAHLFIVNPFHGAGAKMMSLFSTHPPVEERVRRLREMRRGVRYA

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=291, Percent_Identity=30.2405498281787, Blast_Score=98, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 33285; Mature: 33154

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWSEAAQPRGMSPKAGVGRNYAKTAMLMALLIALLAIGGNVVGGMQGMLLFGGLGLVFN
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
FVSYWFSDRLALMAHRARPVTREELPQVYEIVERLTRRAGMPMPRVYVIPSETPNAFATG
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCC
RNPSHAAVAVTEGILRILDRRQLEGVLAHELAHVRNRDILISTVAAAVAGLISTLGYVVR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
WGALLGGMRREDDRGGSALELLAWAILAPLVALVIQLAVSRSREYGADASGAELVGDPEP
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
LAEALLALERGNEAIPYQYGGPATAHLFIVNPFHGAGAKMMSLFSTHPPVEERVRRLREM
HHHHHHHHHCCCCCCCEECCCCCEEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHH
RRGVRYA
HHCCCCC
>Mature Secondary Structure 
SWSEAAQPRGMSPKAGVGRNYAKTAMLMALLIALLAIGGNVVGGMQGMLLFGGLGLVFN
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
FVSYWFSDRLALMAHRARPVTREELPQVYEIVERLTRRAGMPMPRVYVIPSETPNAFATG
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCC
RNPSHAAVAVTEGILRILDRRQLEGVLAHELAHVRNRDILISTVAAAVAGLISTLGYVVR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
WGALLGGMRREDDRGGSALELLAWAILAPLVALVIQLAVSRSREYGADASGAELVGDPEP
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
LAEALLALERGNEAIPYQYGGPATAHLFIVNPFHGAGAKMMSLFSTHPPVEERVRRLREM
HHHHHHHHHCCCCCCCEECCCCCEEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHH
RRGVRYA
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA