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The map label for this gene is mdmB [H]

Identifier: 220918113

GI number: 220918113

Start: 3339266

End: 3340417

Strand: Direct

Name: mdmB [H]

Synonym: A2cp1_3016

Alternate gene names: 220918113

Gene position: 3339266-3340417 (Clockwise)

Preceding gene: 220918112

Following gene: 220918115

Centisome position: 66.4

GC content: 78.82

Gene sequence:

>1152_bases
GTGCCGTCCGCTCGCGACGACCGCCTGGCGCCGCTCACCGGCATCCGCTTCGCGGCCGCGCTCGGGATCCTGCTCTTCCA
CTACGGTGGCCCGCTGGTCGCGAGCGCCCCGGCGTGGGTGCGCACGCTGCAGACCGGCGGCCACGCCTGGGTGAGCCTGT
TCTACGTGCTGTCCGGGTTCGTCCTCGCCTGGGCCAACCCGCACCCGATGGACCGCGCCGAGCGGCGCGCGTTCCTCACG
GCGCGGCTCGCGCGGCTCTACCCGGCCTACCTGCTCGCGTTCGCGCTCTCGGCGCCGTTCGCCCTGTCGCGCTGGTCGGG
TGACGGCGCGGGCGGGCTGGCGAAGGCGGCCGTGGTGGCAGGCGCCTCCCTGCTGCTGGTGCACGCGTGGCTCCCTCCCA
TCTCGCGGCTGTGGAACGCGCCGGGCTGGTCCACCTCGGCGATCGCGACGTTCTACGCGCTCTTCCCGTTCGCGACCGCG
CGCCTCGCCCGGCTCTCGCGGCGCGGGCTCGCGGCGGCGCTCTGCGCCGCATGGGCGGCGTCCCTCGCGCTCCCGCTCGC
GTACCTCGCGCTGCGCCCGGACGGCCCGGGCGCGGAGCTGCTGCGGCACGAGCCGCGCTGGCTCGAGGCGCTGAAGTTCC
ACCCGGTGGCGCGCCTGGGGGAGTTCCTGGCCGGCGTGGCGCTGGGGCTGCTGCTCCGCCGCGGCGCCGCGCTGCCGCGC
CGCCTGGCCGCCCCGGCCGCGGCGCTCGCGCTCGCAGCGGCCGTCGCGGCGCTGGGCTGGGGCGGCTTCCCGTACGTGCT
CGTGCACAACGGGCTGCTCGTGCCGCTCTGGGCGCTGCTCGTCGCGGGGCTCGCGGGGGTGGCTGCGTCGGGCGGCGCGC
TGGGGCGCGCGCTGTCGGCGCGGCCGCTCCAGGCGCTCGGGGAGGCGAGCTTCGCGCTCTACGCGCTGCAGGACCCGCTG
TGGCGCTGGGCGGAGCTGCTGCTGCGCACGCCGGGGACGCCGGCGTCGCCTGCGTTCGTGCTCGGGTTCTCGGCGGTCGC
GGTCGCCATCTCGCTGGGCGTGTCGCGCTGGCTCGAGCGGCCCGCACGTCGCGCGCTGCGGGCGGCCCTGGGCCCGGCGC
CGTTCGCCGCCGCGCGCCCGCCCGCGCCGTAG

Upstream 100 bases:

>100_bases
TACTGAGACCGGCCCTTCCCGTTCGGAAGGCCCGCGCGTTCCCCCGCGCCTCCCGGGGCGCCCCGTACCCTTCCCCTCGC
CCCGCCCGCATGTTGCTGGG

Downstream 100 bases:

>100_bases
CGCCGGGTGCGGGTCCGGAGGCCGCGGCTCCCGGATCAGGAGGCCGGCTGCTCCGGCTGCCCGCCCGGCTTCCGCGGCCC
GGGGAGCCCGACGATCGCGC

Product: acyltransferase 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MPSARDDRLAPLTGIRFAAALGILLFHYGGPLVASAPAWVRTLQTGGHAWVSLFYVLSGFVLAWANPHPMDRAERRAFLT
ARLARLYPAYLLAFALSAPFALSRWSGDGAGGLAKAAVVAGASLLLVHAWLPPISRLWNAPGWSTSAIATFYALFPFATA
RLARLSRRGLAAALCAAWAASLALPLAYLALRPDGPGAELLRHEPRWLEALKFHPVARLGEFLAGVALGLLLRRGAALPR
RLAAPAAALALAAAVAALGWGGFPYVLVHNGLLVPLWALLVAGLAGVAASGGALGRALSARPLQALGEASFALYALQDPL
WRWAELLLRTPGTPASPAFVLGFSAVAVAISLGVSRWLERPARRALRAALGPAPFAAARPPAP

Sequences:

>Translated_383_residues
MPSARDDRLAPLTGIRFAAALGILLFHYGGPLVASAPAWVRTLQTGGHAWVSLFYVLSGFVLAWANPHPMDRAERRAFLT
ARLARLYPAYLLAFALSAPFALSRWSGDGAGGLAKAAVVAGASLLLVHAWLPPISRLWNAPGWSTSAIATFYALFPFATA
RLARLSRRGLAAALCAAWAASLALPLAYLALRPDGPGAELLRHEPRWLEALKFHPVARLGEFLAGVALGLLLRRGAALPR
RLAAPAAALALAAAVAALGWGGFPYVLVHNGLLVPLWALLVAGLAGVAASGGALGRALSARPLQALGEASFALYALQDPL
WRWAELLLRTPGTPASPAFVLGFSAVAVAISLGVSRWLERPARRALRAALGPAPFAAARPPAP
>Mature_382_residues
PSARDDRLAPLTGIRFAAALGILLFHYGGPLVASAPAWVRTLQTGGHAWVSLFYVLSGFVLAWANPHPMDRAERRAFLTA
RLARLYPAYLLAFALSAPFALSRWSGDGAGGLAKAAVVAGASLLLVHAWLPPISRLWNAPGWSTSAIATFYALFPFATAR
LARLSRRGLAAALCAAWAASLALPLAYLALRPDGPGAELLRHEPRWLEALKFHPVARLGEFLAGVALGLLLRRGAALPRR
LAAPAAALALAAAVAALGWGGFPYVLVHNGLLVPLWALLVAGLAGVAASGGALGRALSARPLQALGEASFALYALQDPLW
RWAELLLRTPGTPASPAFVLGFSAVAVAISLGVSRWLERPARRALRAALGPAPFAAARPPAP

Specific function: Catalyzes the acylation of the mycaminose sugar during midecamycin biosynthesis [H]

COG id: COG1835

COG function: function code I; Predicted acyltransferases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyltransferase 3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002656 [H]

Pfam domain/function: PF01757 Acyl_transf_3 [H]

EC number: NA

Molecular weight: Translated: 40114; Mature: 39982

Theoretical pI: Translated: 12.09; Mature: 12.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSARDDRLAPLTGIRFAAALGILLFHYGGPLVASAPAWVRTLQTGGHAWVSLFYVLSGF
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHCCCHHHHHHHHHHHHH
VLAWANPHPMDRAERRAFLTARLARLYPAYLLAFALSAPFALSRWSGDGAGGLAKAAVVA
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHH
GASLLLVHAWLPPISRLWNAPGWSTSAIATFYALFPFATARLARLSRRGLAAALCAAWAA
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLALPLAYLALRPDGPGAELLRHEPRWLEALKFHPVARLGEFLAGVALGLLLRRGAALPR
HHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHH
RLAAPAAALALAAAVAALGWGGFPYVLVHNGLLVPLWALLVAGLAGVAASGGALGRALSA
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
RPLQALGEASFALYALQDPLWRWAELLLRTPGTPASPAFVLGFSAVAVAISLGVSRWLER
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
PARRALRAALGPAPFAAARPPAP
HHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
PSARDDRLAPLTGIRFAAALGILLFHYGGPLVASAPAWVRTLQTGGHAWVSLFYVLSGF
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHCCCHHHHHHHHHHHHH
VLAWANPHPMDRAERRAFLTARLARLYPAYLLAFALSAPFALSRWSGDGAGGLAKAAVVA
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHH
GASLLLVHAWLPPISRLWNAPGWSTSAIATFYALFPFATARLARLSRRGLAAALCAAWAA
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLALPLAYLALRPDGPGAELLRHEPRWLEALKFHPVARLGEFLAGVALGLLLRRGAALPR
HHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHH
RLAAPAAALALAAAVAALGWGGFPYVLVHNGLLVPLWALLVAGLAGVAASGGALGRALSA
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
RPLQALGEASFALYALQDPLWRWAELLLRTPGTPASPAFVLGFSAVAVAISLGVSRWLER
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
PARRALRAALGPAPFAAARPPAP
HHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1629172 [H]