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The map label for this gene is fabD [H]

Identifier: 220918032

GI number: 220918032

Start: 3245555

End: 3246496

Strand: Reverse

Name: fabD [H]

Synonym: A2cp1_2933

Alternate gene names: 220918032

Gene position: 3246496-3245555 (Counterclockwise)

Preceding gene: 220918033

Following gene: 220918031

Centisome position: 64.55

GC content: 74.84

Gene sequence:

>942_bases
ATGGGCAAGCTGGCGTTCGTCTTCCCGGGGCAGGGCTCGCAGGCGGTCGGCATGGGCAAGGAGCTCCACGACGCCTTCCC
GGAGGCGCGGGAGATCTTCCAGGAGGTGGACGAGGCGCTGGGCGAGAAGCTCTCGGCCCTGTGCTTCGGCGGCCCCGAGG
ACCAGCTCAAGCTCACCGCCAACACGCAGCCCTCGATCCTGACCGTCTCGTCCGCGGCGGCGGCGGTGCTCGCGAACCAG
GGGCTGGTCCCGGACTACGTGGCCGGCCACTCGCTGGGCGAGTACTCGGCGCTGGTGGCGGTGGGCGCGTGCGGCGCCGC
CGAGGCGGCGCGCGCGGTGCGGGCGCGCGGCACGTTCATGCAGGAGGCGGTGCCGGCGGGGCAGGGCGCCATGAGCGCGG
TGCTCGGGCTCGATCCGGCGCGCGTCCGCGAGATCTGCGCCGCGGTGGCGGCGGAGACCGGGCAGGTGGTCTCGCCCGCG
AACTACAACGAGCCCGCCCAGACGGTGATCGCGGGCGCGGCCGGCGCCGTGGAGCAGGCCGGCGCGCGGCTCAAGGAGGC
CGGCGCGAAGCGCGTGCTGCCGCTGCCGGTGTCCGCCCCCTTCCACTCGGCGCTCATGGCGCCGGTGAAGGCCCGGCTCG
AGCCGGTGCTGCGCGCGATGCCCTGGAGGGCGCCGCTGCGGCCGGTGGTGACGAACGTCGAGGCGAAGCCGAACCAGGAC
GCGTCGCGGGTGGTCCCGCTGCTCGTCGAGCAGGTGACCGCGCCGGTGCGCTGGATCGAGTGCGTCGAGGAGCTGGTCCG
GCTGGGCGTGACCCGGGTGGTCGAGGTCGGCCCGGGCAAGGTGCTCTCGGGGCTGCTGCGCCGCATCGACCGCTCGGTCG
AGGCGTTCAACGTCGAGGATCGCGCGTCGCTGGAGAAGACGCTCGCCGCGCTGAAGGGCTAG

Upstream 100 bases:

>100_bases
CGGCTGGCTGAAGCCCGGCGACACCGTCCTGATGATGGCGATCGGCGGCGGCATGGCCTGGGGCGCCAGCGTGGTGCGCT
GGTAGGCGGGGAGACCGGAC

Downstream 100 bases:

>100_bases
AGGACCGAGATGACCTTCGACTTCACCGGGAAGACCGCGCTCGTCACCGGCGCCTCGCGCGGCATCGGCCGCGCGGTGGC
GGTGGCGCTGGCGCGCGGCG

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MGKLAFVFPGQGSQAVGMGKELHDAFPEAREIFQEVDEALGEKLSALCFGGPEDQLKLTANTQPSILTVSSAAAAVLANQ
GLVPDYVAGHSLGEYSALVAVGACGAAEAARAVRARGTFMQEAVPAGQGAMSAVLGLDPARVREICAAVAAETGQVVSPA
NYNEPAQTVIAGAAGAVEQAGARLKEAGAKRVLPLPVSAPFHSALMAPVKARLEPVLRAMPWRAPLRPVVTNVEAKPNQD
ASRVVPLLVEQVTAPVRWIECVEELVRLGVTRVVEVGPGKVLSGLLRRIDRSVEAFNVEDRASLEKTLAALKG

Sequences:

>Translated_313_residues
MGKLAFVFPGQGSQAVGMGKELHDAFPEAREIFQEVDEALGEKLSALCFGGPEDQLKLTANTQPSILTVSSAAAAVLANQ
GLVPDYVAGHSLGEYSALVAVGACGAAEAARAVRARGTFMQEAVPAGQGAMSAVLGLDPARVREICAAVAAETGQVVSPA
NYNEPAQTVIAGAAGAVEQAGARLKEAGAKRVLPLPVSAPFHSALMAPVKARLEPVLRAMPWRAPLRPVVTNVEAKPNQD
ASRVVPLLVEQVTAPVRWIECVEELVRLGVTRVVEVGPGKVLSGLLRRIDRSVEAFNVEDRASLEKTLAALKG
>Mature_312_residues
GKLAFVFPGQGSQAVGMGKELHDAFPEAREIFQEVDEALGEKLSALCFGGPEDQLKLTANTQPSILTVSSAAAAVLANQG
LVPDYVAGHSLGEYSALVAVGACGAAEAARAVRARGTFMQEAVPAGQGAMSAVLGLDPARVREICAAVAAETGQVVSPAN
YNEPAQTVIAGAAGAVEQAGARLKEAGAKRVLPLPVSAPFHSALMAPVKARLEPVLRAMPWRAPLRPVVTNVEAKPNQDA
SRVVPLLVEQVTAPVRWIECVEELVRLGVTRVVEVGPGKVLSGLLRRIDRSVEAFNVEDRASLEKTLAALKG

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=302, Percent_Identity=33.4437086092715, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI27477045, Length=111, Percent_Identity=39.6396396396396, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1787334, Length=296, Percent_Identity=49.6621621621622, Blast_Score=239, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI17550940, Length=300, Percent_Identity=30.6666666666667, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71984332, Length=295, Percent_Identity=28.8135593220339, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI212642053, Length=313, Percent_Identity=26.1980830670927, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24665753, Length=312, Percent_Identity=33.0128205128205, Blast_Score=131, Evalue=5e-31,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32604; Mature: 32473

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKLAFVFPGQGSQAVGMGKELHDAFPEAREIFQEVDEALGEKLSALCFGGPEDQLKLTA
CCCEEEEECCCCCCHHCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
NTQPSILTVSSAAAAVLANQGLVPDYVAGHSLGEYSALVAVGACGAAEAARAVRARGTFM
CCCCCEEEEHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
QEAVPAGQGAMSAVLGLDPARVREICAAVAAETGQVVSPANYNEPAQTVIAGAAGAVEQA
HHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHH
GARLKEAGAKRVLPLPVSAPFHSALMAPVKARLEPVLRAMPWRAPLRPVVTNVEAKPNQD
HHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCC
ASRVVPLLVEQVTAPVRWIECVEELVRLGVTRVVEVGPGKVLSGLLRRIDRSVEAFNVED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHH
RASLEKTLAALKG
HHHHHHHHHHHCC
>Mature Secondary Structure 
GKLAFVFPGQGSQAVGMGKELHDAFPEAREIFQEVDEALGEKLSALCFGGPEDQLKLTA
CCEEEEECCCCCCHHCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
NTQPSILTVSSAAAAVLANQGLVPDYVAGHSLGEYSALVAVGACGAAEAARAVRARGTFM
CCCCCEEEEHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
QEAVPAGQGAMSAVLGLDPARVREICAAVAAETGQVVSPANYNEPAQTVIAGAAGAVEQA
HHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHH
GARLKEAGAKRVLPLPVSAPFHSALMAPVKARLEPVLRAMPWRAPLRPVVTNVEAKPNQD
HHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCC
ASRVVPLLVEQVTAPVRWIECVEELVRLGVTRVVEVGPGKVLSGLLRRIDRSVEAFNVED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHH
RASLEKTLAALKG
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]