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The map label for this gene is cph2 [H]

Identifier: 220917989

GI number: 220917989

Start: 3193111

End: 3194595

Strand: Direct

Name: cph2 [H]

Synonym: A2cp1_2890

Alternate gene names: 220917989

Gene position: 3193111-3194595 (Clockwise)

Preceding gene: 220917983

Following gene: 220917991

Centisome position: 63.49

GC content: 75.42

Gene sequence:

>1485_bases
ATGCTCCGCTCGATCCGACGCTCCCTCGGCCGCAAGCTGCTCGTCGCGGTGGGGCTCCCCTCGCTGGCGTTCACGCTGGC
CCTCGTGCTCTGGCTGCGGCACCGGACCCGCTTCGCCGCGCCCGACCTCGAGCCGGTCTACGGCATCGCGGTGATCGCGA
TCCTGCTGTTCGGCGCGCTGATGGGGGTGACGTTCGCGCTGGCCATGCGCTGGGTGATCGAGCAGCCGCTCCAGCGGCTG
GCCGCCGGCCTGCGCCACGTGCGCGAGGGCGACTATCTCTACCGCCTGCCGGTGGAGGGGCCGGACGAGCTGGGGATGGT
GGCGGAGACGTTCAACACCACCCTGGCGGCGCTCACCGATCTGCACGCCCGGCGCATCGAGGACGAGCGCGAGCGCGTCC
TCACGGCGCAGCTGGAGGCGCGCGTGAAGGAGCTGACGCTCCTGTTCGACCTGGCGCGCCGGCTCGGCGGCACGCTCGAG
CTGGACCGGCTGGTGGCGACGCTGACCGAGCTGGTGGGCCGGGGGCTCGGCGACCACGCGTTCGCGCTGCTCCTCGCCGA
GGAGGGCACCGGCGACCTGGTGGTCCGGAGCGTGTCCGGGCTGCCCGAGTCCGCGAACGGCGTCCGCATCCGGGCGGGCG
AGGGCCCGGCCGGCTGGGCGGTGCGCGAGCGCGCGACCGTCCTCGTGAAGGACACCGGCGCCGACCCGCGCCGGCCGGTG
CTGGCCTGGCAGGGCGAGGCGCAGGGCTCGATCCTGGCCGTCCCCATGATCCACCGCGAGGACTGCGCCGGCGTGCTCGC
GTTCTTCCGGCCCGCCACCGACGCGTTCCCGCCCGACGAGGTCCGGCTGCTCGAGTCGGTCGCGGGCCAGGCCGCGCTCG
CCATCGAGAACGCCCGGCTGCACCAGAAGATGGTCCGGCTCTCGCAAAGCGACGCGCTCACCGGCGTCCACAACCGGCGC
AGCCTGTTCGCGCGACTCGACATGGAGCGGGAGCGCTGCGAGCGGTTCGACCACACCATGGCGCTGGCCCTGGTGGACGT
GGACCGCTTCAAGCAGTTCAACGAGGCGTTCGGGCACGCGGCCGGCGATGGCATCCTTCGCCGCGTCGCGGAGCTGCTCG
CGGGGGCGGTGCGCAAGGTGGACCTGGTGGCCCGCTACGGCGGCGAGGAGTTCGCGGTGATCTTCCCGCGCGCCGACCGC
GCGGCGGCGCTGCTCGCGGCCGAGAAGCTGCGGCAGGCGGTGGAGGCCGCGGCCCTCCCGCACGACGCCTCGGAGCGCGG
CCGCGTGACCATCTCGGTGGGCGTGGCGGTGTGGCCCGACGACGCCCGGGACCTGGGCGCGCTCATCGACGCCGCCGACG
CCGCGCTGTACGCGGCGAAGCGCGCCGGGCGCGACGCCGTCCGCGCCCACGAGGCGGGGATGCGCGTCCACCCCGGCCGG
CGCCGCGACGTGCGGACGACCGCCGACGCCGAGGCGGACGCCTAG

Upstream 100 bases:

>100_bases
CACGAGGTCCATCCCGCTCTCATACCAGAGGGCGCCGGGCCGGGGGTGAGGGGGTCCTTGATCGCCTCCCGCGCGGGCAC
TACGCTTGCCGGTCCTGCCC

Downstream 100 bases:

>100_bases
AGCGGCGCTGCGCCCCGCCCCGCCCTGCTCGCCGGTCCCCTGCGCCGCCGCGGGCGGCTGCGCCGCGCGCGCGCCGGCGC
CCGGCGGCTCGCTCCGCTCG

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 494; Mature: 494

Protein sequence:

>494_residues
MLRSIRRSLGRKLLVAVGLPSLAFTLALVLWLRHRTRFAAPDLEPVYGIAVIAILLFGALMGVTFALAMRWVIEQPLQRL
AAGLRHVREGDYLYRLPVEGPDELGMVAETFNTTLAALTDLHARRIEDERERVLTAQLEARVKELTLLFDLARRLGGTLE
LDRLVATLTELVGRGLGDHAFALLLAEEGTGDLVVRSVSGLPESANGVRIRAGEGPAGWAVRERATVLVKDTGADPRRPV
LAWQGEAQGSILAVPMIHREDCAGVLAFFRPATDAFPPDEVRLLESVAGQAALAIENARLHQKMVRLSQSDALTGVHNRR
SLFARLDMERERCERFDHTMALALVDVDRFKQFNEAFGHAAGDGILRRVAELLAGAVRKVDLVARYGGEEFAVIFPRADR
AAALLAAEKLRQAVEAAALPHDASERGRVTISVGVAVWPDDARDLGALIDAADAALYAAKRAGRDAVRAHEAGMRVHPGR
RRDVRTTADAEADA

Sequences:

>Translated_494_residues
MLRSIRRSLGRKLLVAVGLPSLAFTLALVLWLRHRTRFAAPDLEPVYGIAVIAILLFGALMGVTFALAMRWVIEQPLQRL
AAGLRHVREGDYLYRLPVEGPDELGMVAETFNTTLAALTDLHARRIEDERERVLTAQLEARVKELTLLFDLARRLGGTLE
LDRLVATLTELVGRGLGDHAFALLLAEEGTGDLVVRSVSGLPESANGVRIRAGEGPAGWAVRERATVLVKDTGADPRRPV
LAWQGEAQGSILAVPMIHREDCAGVLAFFRPATDAFPPDEVRLLESVAGQAALAIENARLHQKMVRLSQSDALTGVHNRR
SLFARLDMERERCERFDHTMALALVDVDRFKQFNEAFGHAAGDGILRRVAELLAGAVRKVDLVARYGGEEFAVIFPRADR
AAALLAAEKLRQAVEAAALPHDASERGRVTISVGVAVWPDDARDLGALIDAADAALYAAKRAGRDAVRAHEAGMRVHPGR
RRDVRTTADAEADA
>Mature_494_residues
MLRSIRRSLGRKLLVAVGLPSLAFTLALVLWLRHRTRFAAPDLEPVYGIAVIAILLFGALMGVTFALAMRWVIEQPLQRL
AAGLRHVREGDYLYRLPVEGPDELGMVAETFNTTLAALTDLHARRIEDERERVLTAQLEARVKELTLLFDLARRLGGTLE
LDRLVATLTELVGRGLGDHAFALLLAEEGTGDLVVRSVSGLPESANGVRIRAGEGPAGWAVRERATVLVKDTGADPRRPV
LAWQGEAQGSILAVPMIHREDCAGVLAFFRPATDAFPPDEVRLLESVAGQAALAIENARLHQKMVRLSQSDALTGVHNRR
SLFARLDMERERCERFDHTMALALVDVDRFKQFNEAFGHAAGDGILRRVAELLAGAVRKVDLVARYGGEEFAVIFPRADR
AAALLAAEKLRQAVEAAALPHDASERGRVTISVGVAVWPDDARDLGALIDAADAALYAAKRAGRDAVRAHEAGMRVHPGR
RRDVRTTADAEADA

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI145693134, Length=167, Percent_Identity=37.125748502994, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI87081881, Length=174, Percent_Identity=35.632183908046, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1787262, Length=165, Percent_Identity=33.3333333333333, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786584, Length=159, Percent_Identity=33.9622641509434, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1788381, Length=185, Percent_Identity=33.5135135135135, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87082007, Length=160, Percent_Identity=36.25, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787816, Length=173, Percent_Identity=34.1040462427746, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1788085, Length=171, Percent_Identity=30.9941520467836, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787802, Length=190, Percent_Identity=32.6315789473684, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787541, Length=170, Percent_Identity=28.8235294117647, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081977, Length=158, Percent_Identity=28.4810126582279, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081974, Length=163, Percent_Identity=27.6073619631902, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 53853; Mature: 53853

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS50885 HAMP ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRSIRRSLGRKLLVAVGLPSLAFTLALVLWLRHRTRFAAPDLEPVYGIAVIAILLFGAL
CCHHHHHHHCHHEEHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
MGVTFALAMRWVIEQPLQRLAAGLRHVREGDYLYRLPVEGPDELGMVAETFNTTLAALTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
LHARRIEDERERVLTAQLEARVKELTLLFDLARRLGGTLELDRLVATLTELVGRGLGDHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCE
FALLLAEEGTGDLVVRSVSGLPESANGVRIRAGEGPAGWAVRERATVLVKDTGADPRRPV
EEEEEECCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCEECCCCEEEEEECCCCCCCCE
LAWQGEAQGSILAVPMIHREDCAGVLAFFRPATDAFPPDEVRLLESVAGQAALAIENARL
EEECCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHH
HQKMVRLSQSDALTGVHNRRSLFARLDMERERCERFDHTMALALVDVDRFKQFNEAFGHA
HHHHHHHHHCCCHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AGDGILRRVAELLAGAVRKVDLVARYGGEEFAVIFPRADRAAALLAAEKLRQAVEAAALP
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
HDASERGRVTISVGVAVWPDDARDLGALIDAADAALYAAKRAGRDAVRAHEAGMRVHPGR
CCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCC
RRDVRTTADAEADA
CCCCCCCCCCCCCC
>Mature Secondary Structure
MLRSIRRSLGRKLLVAVGLPSLAFTLALVLWLRHRTRFAAPDLEPVYGIAVIAILLFGAL
CCHHHHHHHCHHEEHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
MGVTFALAMRWVIEQPLQRLAAGLRHVREGDYLYRLPVEGPDELGMVAETFNTTLAALTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
LHARRIEDERERVLTAQLEARVKELTLLFDLARRLGGTLELDRLVATLTELVGRGLGDHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCE
FALLLAEEGTGDLVVRSVSGLPESANGVRIRAGEGPAGWAVRERATVLVKDTGADPRRPV
EEEEEECCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCEECCCCEEEEEECCCCCCCCE
LAWQGEAQGSILAVPMIHREDCAGVLAFFRPATDAFPPDEVRLLESVAGQAALAIENARL
EEECCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHH
HQKMVRLSQSDALTGVHNRRSLFARLDMERERCERFDHTMALALVDVDRFKQFNEAFGHA
HHHHHHHHHCCCHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AGDGILRRVAELLAGAVRKVDLVARYGGEEFAVIFPRADRAAALLAAEKLRQAVEAAALP
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
HDASERGRVTISVGVAVWPDDARDLGALIDAADAALYAAKRAGRDAVRAHEAGMRVHPGR
CCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCC
RRDVRTTADAEADA
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]