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The map label for this gene is cusC [C]

Identifier: 220917879

GI number: 220917879

Start: 3067284

End: 3068717

Strand: Direct

Name: cusC [C]

Synonym: A2cp1_2780

Alternate gene names: 220917879

Gene position: 3067284-3068717 (Clockwise)

Preceding gene: 220917878

Following gene: 220917880

Centisome position: 60.99

GC content: 77.82

Gene sequence:

>1434_bases
ATGATCCCTTCCGCCCTGCTCGCCCTCGCGCTCGCCGCGGCCGCGGAGGCCGGCGCCCCCGGCGCGGCCGACCCCGGCAC
CGCACCGCCGGTGCTCACCCTCGACGCCGCGTTCCGTCGCGCCCGCGAGGCCAGCCTCGAGCTGCGCATCGCCGACGAGC
GGCTCGCCCAGGCGCGCACCCTCGCGCGCAAGGCGTGGAGCCACTACCTGCCCCAGGTGACCGCGGGCGCCTCGTACGCC
TGGAACTCCGAGGACGTGGTGCTGGACCTGCCCACCAGCTTCGCGATCCGCGACCTGGGCAGGCCGACCAGCGCGCCGCG
CGCGGCGCTCCCCCCGTACGATCCCGGCCGCCCGTTCTCGCCCGGCAACCTGCCGGGCGAGGCGACCACGCTCGCGCTCA
TCCCGACCTCGATGGAGGAGCTGGAGCTGCAGCGGAAGACGCAGTACGGGGCGCAGGCCGAGGTGAAGCAGGCGCTCCTC
GCGCCGCGGCTCTGGCCTGCCATCCGCAACGCCTACCTTGCCGAGGACGTCGCGAGCGCGCAGGTCGCCGACACGCGCCA
GAAGCTGCTCTTCGGCGTGGCACAGCTCTACTACGGCGCGGCCACCCTCCGCGAAGCGGTCGCGGTGCAGGAGCGGACGC
TCGAGACCTGGCGGCAGCACGAGACGGACGCCGAGCACCTCGCCGCACAGGGCGCCGCGCCGCGCCTGGCGCTGCTGAAG
GCGCGCACCGATCGCGCGCGCGCCGAGCAGGACCTGATCCGGGCGCACAACGCGTACGCGGCGGCCCGGCTCGCCCTCGC
CACGCTGCTGGATCGCGACGCGGACTTCGAGGTGGAGCGACCGCCGGAGCCCCCGCCGCCGTCGGCCGACGCCCAGGCGC
AGGAGGAGCGCGCCGCCCGCCGGCCGGACGTGGAGGCCGCCCGCGCGCGGCTGGCGCTGGCCCAGGGGCAGCGCCGCGAG
GCGGTCGCCGCGTACCTCCCCACGCTGGGCGTGAGCGGGACCTGGCGCTGGGCCAGCATCACCGGCTTCACCGGCGAGCA
CGCCGGCTGGACCGTCCTGCTCGGCCTCCAGTGGACCCTGTTCGACGGCGGCCGGCGCGAGGCCGACCTCGCCGAGGCGG
GCCACCGCGCGGCCGAGGCCGACGCGGCCCTCGCGCTCGCCTCGAACAAGGCGCGCGACGAGGTCCGGCGCGCCCGGCTG
GACCTCGACAGCGCGTCGGCCGCCGCGCGCAAGGCCGAGGAGCAGGCGTCGCTGGCACGCGAGGCGCTGGAGCAGGCCCA
GCGGGCCCACGCCGCCGGCGCCGCCACCTACCTCGAGGTCGCGGACGCCACCAGCGCCGCGTCCTCCGCCGAGCTCGGCC
TGGTCGCGGCCACGCTCGACGCCCGGCTGGCGCGGCTCGCCCTGGCGCGCGCGGCCGGCACGTTCGATCCATGA

Upstream 100 bases:

>100_bases
CGCTGGCGGCGCTCGTGGTCCGCCGGGCCGCCGTGGCGCGCCGCCTGGCCGCGCTCCGGCGCGGGGCCGAGCCGCCCTCC
CCTGCCTCGAGGAGCACCCC

Downstream 100 bases:

>100_bases
CGCCGCCGCGGGCCCCCGCGGACGGCGGCGCCGCCGGTCCGCCCGGGTTGGCCCGCAATTCCTGACCCGTCGGTCAGCTT
CGGTTGCGCCGGCGCGCGCG

Product: outer membrane efflux protein

Products: NA

Alternate protein names: Outer Membrane Efflux Protein Domain-Containing Protein; Outer Membrane Efflux Protein Domain Protein

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MIPSALLALALAAAAEAGAPGAADPGTAPPVLTLDAAFRRAREASLELRIADERLAQARTLARKAWSHYLPQVTAGASYA
WNSEDVVLDLPTSFAIRDLGRPTSAPRAALPPYDPGRPFSPGNLPGEATTLALIPTSMEELELQRKTQYGAQAEVKQALL
APRLWPAIRNAYLAEDVASAQVADTRQKLLFGVAQLYYGAATLREAVAVQERTLETWRQHETDAEHLAAQGAAPRLALLK
ARTDRARAEQDLIRAHNAYAAARLALATLLDRDADFEVERPPEPPPPSADAQAQEERAARRPDVEAARARLALAQGQRRE
AVAAYLPTLGVSGTWRWASITGFTGEHAGWTVLLGLQWTLFDGGRREADLAEAGHRAAEADAALALASNKARDEVRRARL
DLDSASAAARKAEEQASLAREALEQAQRAHAAGAATYLEVADATSAASSAELGLVAATLDARLARLALARAAGTFDP

Sequences:

>Translated_477_residues
MIPSALLALALAAAAEAGAPGAADPGTAPPVLTLDAAFRRAREASLELRIADERLAQARTLARKAWSHYLPQVTAGASYA
WNSEDVVLDLPTSFAIRDLGRPTSAPRAALPPYDPGRPFSPGNLPGEATTLALIPTSMEELELQRKTQYGAQAEVKQALL
APRLWPAIRNAYLAEDVASAQVADTRQKLLFGVAQLYYGAATLREAVAVQERTLETWRQHETDAEHLAAQGAAPRLALLK
ARTDRARAEQDLIRAHNAYAAARLALATLLDRDADFEVERPPEPPPPSADAQAQEERAARRPDVEAARARLALAQGQRRE
AVAAYLPTLGVSGTWRWASITGFTGEHAGWTVLLGLQWTLFDGGRREADLAEAGHRAAEADAALALASNKARDEVRRARL
DLDSASAAARKAEEQASLAREALEQAQRAHAAGAATYLEVADATSAASSAELGLVAATLDARLARLALARAAGTFDP
>Mature_477_residues
MIPSALLALALAAAAEAGAPGAADPGTAPPVLTLDAAFRRAREASLELRIADERLAQARTLARKAWSHYLPQVTAGASYA
WNSEDVVLDLPTSFAIRDLGRPTSAPRAALPPYDPGRPFSPGNLPGEATTLALIPTSMEELELQRKTQYGAQAEVKQALL
APRLWPAIRNAYLAEDVASAQVADTRQKLLFGVAQLYYGAATLREAVAVQERTLETWRQHETDAEHLAAQGAAPRLALLK
ARTDRARAEQDLIRAHNAYAAARLALATLLDRDADFEVERPPEPPPPSADAQAQEERAARRPDVEAARARLALAQGQRRE
AVAAYLPTLGVSGTWRWASITGFTGEHAGWTVLLGLQWTLFDGGRREADLAEAGHRAAEADAALALASNKARDEVRRARL
DLDSASAAARKAEEQASLAREALEQAQRAHAAGAATYLEVADATSAASSAELGLVAATLDARLARLALARAAGTFDP

Specific function: In Pathogenic Strains It Allows The Bacteria To Invade Brain Microvascular Endothelial Cells (Bmec) Thus Allowing It To Cross The Blood-Brain Barrier And Cause Neonatal Meningitis. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Attached To The Outer Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 50778; Mature: 50778

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPSALLALALAAAAEAGAPGAADPGTAPPVLTLDAAFRRAREASLELRIADERLAQART
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHCCEEEEEHHHHHHHHHH
LARKAWSHYLPQVTAGASYAWNSEDVVLDLPTSFAIRDLGRPTSAPRAALPPYDPGRPFS
HHHHHHHHHCCCHHCCCCCCCCCCCEEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PGNLPGEATTLALIPTSMEELELQRKTQYGAQAEVKQALLAPRLWPAIRNAYLAEDVASA
CCCCCCCCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVADTRQKLLFGVAQLYYGAATLREAVAVQERTLETWRQHETDAEHLAAQGAAPRLALLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHH
ARTDRARAEQDLIRAHNAYAAARLALATLLDRDADFEVERPPEPPPPSADAQAQEERAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHC
RPDVEAARARLALAQGQRREAVAAYLPTLGVSGTWRWASITGFTGEHAGWTVLLGLQWTL
CCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEEEEEEE
FDGGRREADLAEAGHRAAEADAALALASNKARDEVRRARLDLDSASAAARKAEEQASLAR
ECCCCCCHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
EALEQAQRAHAAGAATYLEVADATSAASSAELGLVAATLDARLARLALARAAGTFDP
HHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIPSALLALALAAAAEAGAPGAADPGTAPPVLTLDAAFRRAREASLELRIADERLAQART
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHCCEEEEEHHHHHHHHHH
LARKAWSHYLPQVTAGASYAWNSEDVVLDLPTSFAIRDLGRPTSAPRAALPPYDPGRPFS
HHHHHHHHHCCCHHCCCCCCCCCCCEEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PGNLPGEATTLALIPTSMEELELQRKTQYGAQAEVKQALLAPRLWPAIRNAYLAEDVASA
CCCCCCCCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVADTRQKLLFGVAQLYYGAATLREAVAVQERTLETWRQHETDAEHLAAQGAAPRLALLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHH
ARTDRARAEQDLIRAHNAYAAARLALATLLDRDADFEVERPPEPPPPSADAQAQEERAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHC
RPDVEAARARLALAQGQRREAVAAYLPTLGVSGTWRWASITGFTGEHAGWTVLLGLQWTL
CCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEEEEEEE
FDGGRREADLAEAGHRAAEADAALALASNKARDEVRRARLDLDSASAAARKAEEQASLAR
ECCCCCCHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
EALEQAQRAHAAGAATYLEVADATSAASSAELGLVAATLDARLARLALARAAGTFDP
HHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA