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The map label for this gene is slyD [H]

Identifier: 220917839

GI number: 220917839

Start: 3022554

End: 3023045

Strand: Direct

Name: slyD [H]

Synonym: A2cp1_2740

Alternate gene names: 220917839

Gene position: 3022554-3023045 (Clockwise)

Preceding gene: 220917838

Following gene: 220917841

Centisome position: 60.1

GC content: 72.15

Gene sequence:

>492_bases
ATGAAGATCGCGAAGGGCAGCGTCGTCGGCCTCGATTACTCGCTGCACCTCGGAGACGGGAAGGTCGTGGACCAGTCCGA
GCCGGGCGAGCCGCTCACCTACCTCCACGGCGAGGGGCAGATCGTGCCGGGTCTGGAGTCGGCGCTCGAGGGCGTCGACG
TGGGCGAGTCGCGCAAGGTGGTGGTCGCGCCCTCCGACGGGTACGGCGAGCACGATCCGCGCGGCGTGCAGGAGGTGCCG
CGCAAGGCGTTCCCGCCCGGCTTCGACCCGCAGGTCGGGATGGAGCTGACCGCGGAGGGCGCCGACGGCGAGCCGGTGCC
GTTCGCGATCCGCGAGGTGAAGCCGGAGTCGGTGGTGATCGACCTCAACCACCCGCTCGCCGGCAAGACCCTGCACTTCG
AGGTGACGGTGCGCGACGTCCGCGCCGCGACCGCGGAGGAGCTGGAGCACGGTCACGCCCACGGCCCCGAGGGCCACGGG
CACGACCACTAG

Upstream 100 bases:

>100_bases
ACCCCCGGTCGTATTTCCTTGCCAGCCGGTCCCCGGCCGGGAAATACCGGCCGAAGGGAGGCGCACCGCCGTCCCGAGCT
CCACGGCCTCAGGAGGGCCC

Downstream 100 bases:

>100_bases
TCCCTCGGCTCCGCGCCGCCGTCGCGGCGCGACGCTCGGGACGAGCGGCGCGGTCGAAGGGCGCTACGGCGTCGGCGTCA
CCGCGTAGGTCCAGGTCTCG

Product: FKBP-type peptidylprolyl isomerase

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MKIAKGSVVGLDYSLHLGDGKVVDQSEPGEPLTYLHGEGQIVPGLESALEGVDVGESRKVVVAPSDGYGEHDPRGVQEVP
RKAFPPGFDPQVGMELTAEGADGEPVPFAIREVKPESVVIDLNHPLAGKTLHFEVTVRDVRAATAEELEHGHAHGPEGHG
HDH

Sequences:

>Translated_163_residues
MKIAKGSVVGLDYSLHLGDGKVVDQSEPGEPLTYLHGEGQIVPGLESALEGVDVGESRKVVVAPSDGYGEHDPRGVQEVP
RKAFPPGFDPQVGMELTAEGADGEPVPFAIREVKPESVVIDLNHPLAGKTLHFEVTVRDVRAATAEELEHGHAHGPEGHG
HDH
>Mature_163_residues
MKIAKGSVVGLDYSLHLGDGKVVDQSEPGEPLTYLHGEGQIVPGLESALEGVDVGESRKVVVAPSDGYGEHDPRGVQEVP
RKAFPPGFDPQVGMELTAEGADGEPVPFAIREVKPESVVIDLNHPLAGKTLHFEVTVRDVRAATAEELEHGHAHGPEGHG
HDH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=148, Percent_Identity=47.2972972972973, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI1786211, Length=143, Percent_Identity=30.0699300699301, Blast_Score=83, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 17294; Mature: 17294

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAKGSVVGLDYSLHLGDGKVVDQSEPGEPLTYLHGEGQIVPGLESALEGVDVGESRKV
CCCCCCCEEEEEEEEECCCCEEECCCCCCCCEEEECCCCCCCCCHHHHHCCCCCCCCCEE
VVAPSDGYGEHDPRGVQEVPRKAFPPGFDPQVGMELTAEGADGEPVPFAIREVKPESVVI
EEECCCCCCCCCCCCHHHCCHHHCCCCCCCCCCEEEEECCCCCCCCCEEEEECCCCEEEE
DLNHPLAGKTLHFEVTVRDVRAATAEELEHGHAHGPEGHGHDH
ECCCCCCCCEEEEEEEEEHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MKIAKGSVVGLDYSLHLGDGKVVDQSEPGEPLTYLHGEGQIVPGLESALEGVDVGESRKV
CCCCCCCEEEEEEEEECCCCEEECCCCCCCCEEEECCCCCCCCCHHHHHCCCCCCCCCEE
VVAPSDGYGEHDPRGVQEVPRKAFPPGFDPQVGMELTAEGADGEPVPFAIREVKPESVVI
EEECCCCCCCCCCCCHHHCCHHHCCCCCCCCCCEEEEECCCCCCCCCEEEEECCCCEEEE
DLNHPLAGKTLHFEVTVRDVRAATAEELEHGHAHGPEGHGHDH
ECCCCCCCCEEEEEEEEEHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]