Click here to switch to the map view.

The map label for this gene is cspA [H]

Identifier: 220917823

GI number: 220917823

Start: 3004061

End: 3004261

Strand: Reverse

Name: cspA [H]

Synonym: A2cp1_2724

Alternate gene names: 220917823

Gene position: 3004261-3004061 (Counterclockwise)

Preceding gene: 220917824

Following gene: 220917822

Centisome position: 59.73

GC content: 63.68

Gene sequence:

>201_bases
ATGGCACTTGGTACCGTGAAGTGGTTCAACGACGCGAAGGGCTACGGTTTCATCTCCCAGGAGGGCGGGGAGGACGTCTT
CGTTCACCACACGGCCATTCAGATGGATGGCTTCCGCACCCTGAAGGAGGGGGAGCGGGTGGAGTTCGACGTCACCCAGG
GCCCCAAGGGGCTTCAGGCGGCGAACGTCCGCCGTCCGTAG

Upstream 100 bases:

>100_bases
TGTAGGTTTCGGGGATATTTCGCGGCCGAGTCGAGGGTCCGTGCCCCACGACTCCGCGGGCCGGCGGTCGGCCCGGGACA
CACGAAGGAAGCGTGAAGCG

Downstream 100 bases:

>100_bases
AGCATCCGGTCCGCTGGGTGACGAGCGGCCTCGGGTGACCGAGGCCGCTCGCGCTTCTGAGCCTGCTACACGATAGCCTG
GGAGCGTGCGGAGAGGTTCG

Product: cold-shock DNA-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 66; Mature: 65

Protein sequence:

>66_residues
MALGTVKWFNDAKGYGFISQEGGEDVFVHHTAIQMDGFRTLKEGERVEFDVTQGPKGLQAANVRRP

Sequences:

>Translated_66_residues
MALGTVKWFNDAKGYGFISQEGGEDVFVHHTAIQMDGFRTLKEGERVEFDVTQGPKGLQAANVRRP
>Mature_65_residues
ALGTVKWFNDAKGYGFISQEGGEDVFVHHTAIQMDGFRTLKEGERVEFDVTQGPKGLQAANVRRP

Specific function: Inhibits DNA Replication At Both Initiation And Elongation Steps, Most Probably By Binding To The Opened, Single- Stranded Regions At Replication Forks. Plays A Regulatory Role In Chromosomal Replication In Nutrient-Depleted Cells. [C]

COG id: COG1278

COG function: function code K; Cold shock proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CSD (cold-shock) domain [H]

Homologues:

Organism=Homo sapiens, GI224586884, Length=69, Percent_Identity=55.0724637681159, Blast_Score=71, Evalue=2e-13,
Organism=Homo sapiens, GI34098946, Length=69, Percent_Identity=55.0724637681159, Blast_Score=70, Evalue=2e-13,
Organism=Homo sapiens, GI224586882, Length=69, Percent_Identity=55.0724637681159, Blast_Score=70, Evalue=3e-13,
Organism=Homo sapiens, GI156415990, Length=66, Percent_Identity=54.5454545454545, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787107, Length=64, Percent_Identity=64.0625, Blast_Score=88, Evalue=8e-20,
Organism=Escherichia coli, GI1786841, Length=61, Percent_Identity=63.9344262295082, Blast_Score=84, Evalue=2e-18,
Organism=Escherichia coli, GI2367114, Length=61, Percent_Identity=59.0163934426229, Blast_Score=74, Evalue=2e-15,
Organism=Escherichia coli, GI1788126, Length=61, Percent_Identity=57.3770491803279, Blast_Score=74, Evalue=3e-15,
Organism=Escherichia coli, GI1787839, Length=61, Percent_Identity=59.0163934426229, Blast_Score=72, Evalue=5e-15,
Organism=Escherichia coli, GI1789979, Length=61, Percent_Identity=54.0983606557377, Blast_Score=70, Evalue=2e-14,
Organism=Escherichia coli, GI1787834, Length=61, Percent_Identity=54.0983606557377, Blast_Score=69, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17533635, Length=68, Percent_Identity=50, Blast_Score=65, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24658520, Length=62, Percent_Identity=53.2258064516129, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019844
- InterPro:   IPR012156
- InterPro:   IPR011129
- InterPro:   IPR002059
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00313 CSD [H]

EC number: NA

Molecular weight: Translated: 7339; Mature: 7208

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00352 COLD_SHOCK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALGTVKWFNDAKGYGFISQEGGEDVFVHHTAIQMDGFRTLKEGERVEFDVTQGPKGLQA
CCCCCCEECCCCCCCEEEECCCCCEEEEEEEEEEECCCCCCCCCCEEEEECCCCCCCCCC
ANVRRP
CCCCCC
>Mature Secondary Structure 
ALGTVKWFNDAKGYGFISQEGGEDVFVHHTAIQMDGFRTLKEGERVEFDVTQGPKGLQA
CCCCCEECCCCCCCEEEECCCCCEEEEEEEEEEECCCCCCCCCCEEEEECCCCCCCCCC
ANVRRP
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA