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The map label for this gene is add [H]

Identifier: 220917808

GI number: 220917808

Start: 2989214

End: 2990215

Strand: Reverse

Name: add [H]

Synonym: A2cp1_2709

Alternate gene names: 220917808

Gene position: 2990215-2989214 (Counterclockwise)

Preceding gene: 220917809

Following gene: 220917807

Centisome position: 59.46

GC content: 70.76

Gene sequence:

>1002_bases
ATGGCACGCGAGCTCTCGGACCTGCACATCCACGTCGGCGGCGCGGTGGCGCCGCACATCCTGTGGTCCATCGCCCACGA
CCAGGGCTTCAAGCTGCCGGTCGCGAGCTACTGGGAGTTCAAGGAGCTGATCTCGGCGCGCCCGGGGAAGGTGCGGTCGC
TGGACGAGTACCTGGCGGTGATGCACGAGTGGACCGAGAAGATCCAGTCGTCCCCGCAGGCGATGGAGCGCAGCGTCTAC
GAGGTCATCGGCAAGGAGTACCGCTCGTCGCGGGTCTCGCTCATCGAGCTGCGCTTCAACCCGATGAAGCGCAACGTCGG
CGGCGAGCGCGACCTCGACCACATCATCCACGCCGCGCTGCGCGGGATGGACCGGGCCGTCCTCGAGTACGGCGTGCAGG
CCGGGCTCATCTTCTGCCTGGCGCGCGAGTTCCCCGCGCACCTGAACGAGATCCTGGTCGAGAAGGCCATCAAGTACCGG
CGGCGCGGCGTGGTCGGCATCGACCTGGCGGGCACCGAGCGCCACGCGCTCGAGCTGATGCCGGAGGAGGTCGGGCGGTA
CCGCGAGCTGTACGCGCGGGCGCGGCGCGCCGGGCTGAAGACGACCGTGCACACCGGCGAGACCGCCACCACCGGCGCCG
AGGGGGTCCGGGCGGTGGTGGAGCAGCTCGAGCCGCACCGCATCGGCCATGGCATCTGCGCGGCGCGGGACGAGAAGGTC
ATGGACCTGCTCCGCGAGCGCGGCGTGGTGCTGGAGATCTGCCCCAGCTCGAACCTCGCCACGCGGGCGGTGGGGTCGAT
CGAGGAGCTGGGGCAGGTGCTCGCGCGCTTCTGGGATCGCGGCGTGCGGTTCACCATCAACACCGACGGCCCGTACCTGC
TCGACACGAACATGCGCGCCGAGGTGCGCCTGCTGCGCGAGTCCGGCGTGCTCGCGGAGGAGCAGATCGACCAGGCCCTG
CGGTGGGCCCGGGAGGCCACCTTCATCGGCGAGCTGCCCTGA

Upstream 100 bases:

>100_bases
CTCGGGCTCGGCGCGCCCGGCGAGTCGGCGCCGGACGAGAACGGGTAGCCGCGTCGGAGAAGCGCTGGCGTGCCTCGCGC
CGCGGCGGTATCTCGGGCCG

Downstream 100 bases:

>100_bases
CGAGGCGCGCGTTGAATACGGCCGGGAGCGCGCGCGTACGTCCTCGCAGCGGGTGCGCGCGGATCGACCGCGGCCCCGCG
CCGGAGGTACCCCAAATGAA

Product: Adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MARELSDLHIHVGGAVAPHILWSIAHDQGFKLPVASYWEFKELISARPGKVRSLDEYLAVMHEWTEKIQSSPQAMERSVY
EVIGKEYRSSRVSLIELRFNPMKRNVGGERDLDHIIHAALRGMDRAVLEYGVQAGLIFCLAREFPAHLNEILVEKAIKYR
RRGVVGIDLAGTERHALELMPEEVGRYRELYARARRAGLKTTVHTGETATTGAEGVRAVVEQLEPHRIGHGICAARDEKV
MDLLRERGVVLEICPSSNLATRAVGSIEELGQVLARFWDRGVRFTINTDGPYLLDTNMRAEVRLLRESGVLAEEQIDQAL
RWAREATFIGELP

Sequences:

>Translated_333_residues
MARELSDLHIHVGGAVAPHILWSIAHDQGFKLPVASYWEFKELISARPGKVRSLDEYLAVMHEWTEKIQSSPQAMERSVY
EVIGKEYRSSRVSLIELRFNPMKRNVGGERDLDHIIHAALRGMDRAVLEYGVQAGLIFCLAREFPAHLNEILVEKAIKYR
RRGVVGIDLAGTERHALELMPEEVGRYRELYARARRAGLKTTVHTGETATTGAEGVRAVVEQLEPHRIGHGICAARDEKV
MDLLRERGVVLEICPSSNLATRAVGSIEELGQVLARFWDRGVRFTINTDGPYLLDTNMRAEVRLLRESGVLAEEQIDQAL
RWAREATFIGELP
>Mature_332_residues
ARELSDLHIHVGGAVAPHILWSIAHDQGFKLPVASYWEFKELISARPGKVRSLDEYLAVMHEWTEKIQSSPQAMERSVYE
VIGKEYRSSRVSLIELRFNPMKRNVGGERDLDHIIHAALRGMDRAVLEYGVQAGLIFCLAREFPAHLNEILVEKAIKYRR
RGVVGIDLAGTERHALELMPEEVGRYRELYARARRAGLKTTVHTGETATTGAEGVRAVVEQLEPHRIGHGICAARDEKVM
DLLRERGVVLEICPSSNLATRAVGSIEELGQVLARFWDRGVRFTINTDGPYLLDTNMRAEVRLLRESGVLAEEQIDQALR
WAREATFIGELP

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=337, Percent_Identity=25.5192878338279, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI1787910, Length=328, Percent_Identity=28.3536585365854, Blast_Score=117, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI32565969, Length=332, Percent_Identity=28.6144578313253, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17538512, Length=332, Percent_Identity=28.6144578313253, Blast_Score=107, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6324188, Length=295, Percent_Identity=27.4576271186441, Blast_Score=96, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24645260, Length=326, Percent_Identity=25.7668711656442, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 37549; Mature: 37417

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARELSDLHIHVGGAVAPHILWSIAHDQGFKLPVASYWEFKELISARPGKVRSLDEYLAV
CCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHH
MHEWTEKIQSSPQAMERSVYEVIGKEYRSSRVSLIELRFNPMKRNVGGERDLDHIIHAAL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHCCCCCCCHHHHHHHHH
RGMDRAVLEYGVQAGLIFCLAREFPAHLNEILVEKAIKYRRRGVVGIDLAGTERHALELM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHC
PEEVGRYRELYARARRAGLKTTVHTGETATTGAEGVRAVVEQLEPHRIGHGICAARDEKV
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHCCCHHCCCCHHHCCHHHH
MDLLRERGVVLEICPSSNLATRAVGSIEELGQVLARFWDRGVRFTINTDGPYLLDTNMRA
HHHHHHCCCEEEECCCCCCHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCHH
EVRLLRESGVLAEEQIDQALRWAREATFIGELP
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ARELSDLHIHVGGAVAPHILWSIAHDQGFKLPVASYWEFKELISARPGKVRSLDEYLAV
CCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHH
MHEWTEKIQSSPQAMERSVYEVIGKEYRSSRVSLIELRFNPMKRNVGGERDLDHIIHAAL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHCCCCCCCHHHHHHHHH
RGMDRAVLEYGVQAGLIFCLAREFPAHLNEILVEKAIKYRRRGVVGIDLAGTERHALELM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHC
PEEVGRYRELYARARRAGLKTTVHTGETATTGAEGVRAVVEQLEPHRIGHGICAARDEKV
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHCCCHHCCCCHHHCCHHHH
MDLLRERGVVLEICPSSNLATRAVGSIEELGQVLARFWDRGVRFTINTDGPYLLDTNMRA
HHHHHHCCCEEEECCCCCCHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCHH
EVRLLRESGVLAEEQIDQALRWAREATFIGELP
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA