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The map label for this gene is cspA [H]

Identifier: 220917780

GI number: 220917780

Start: 2960184

End: 2960387

Strand: Direct

Name: cspA [H]

Synonym: A2cp1_2681

Alternate gene names: 220917780

Gene position: 2960184-2960387 (Clockwise)

Preceding gene: 220917779

Following gene: 220917781

Centisome position: 58.86

GC content: 66.18

Gene sequence:

>204_bases
ATGGCGAGTGGTACTGTGAAGTGGTTCAATGACGCGAAGGGCTTCGGCTTCATCTCCCAGGACGGTGGCGGCGAGGACGT
GTTCGTCCACCACACCGCGATCGTCGCCGAGGGCTTCCGCAGCCTGCAGGAAGGGCAGCGGGTGGAGTTCGAGGTGAAGA
AGGGCCCCAAGGGGCTGCAGGCCGCGAACGTCCGGGGGGCGTAG

Upstream 100 bases:

>100_bases
TTCACCACCCTGCGGCTACGTTACAGGCGTCCCACGCCTCTGGCGCGGCTCGGGGCCGACGGGAAGTGTATCCCGGACGA
ACACGGAAAGAAGTGTGCAG

Downstream 100 bases:

>100_bases
CCGCCGGTCGGAGTCGCACGTGTCGTGGGGGCCCGGCCGCTCGGCCGGGCCTTCGCGCTTTAGGCCCCCAACCTCGAAGG
AGCGCACACCATGGCCTTCC

Product: cold-shock DNA-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 67; Mature: 66

Protein sequence:

>67_residues
MASGTVKWFNDAKGFGFISQDGGGEDVFVHHTAIVAEGFRSLQEGQRVEFEVKKGPKGLQAANVRGA

Sequences:

>Translated_67_residues
MASGTVKWFNDAKGFGFISQDGGGEDVFVHHTAIVAEGFRSLQEGQRVEFEVKKGPKGLQAANVRGA
>Mature_66_residues
ASGTVKWFNDAKGFGFISQDGGGEDVFVHHTAIVAEGFRSLQEGQRVEFEVKKGPKGLQAANVRGA

Specific function: Inhibits DNA Replication At Both Initiation And Elongation Steps, Most Probably By Binding To The Opened, Single- Stranded Regions At Replication Forks. Plays A Regulatory Role In Chromosomal Replication In Nutrient-Depleted Cells. [C]

COG id: COG1278

COG function: function code K; Cold shock proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CSD (cold-shock) domain [H]

Homologues:

Organism=Homo sapiens, GI224586884, Length=68, Percent_Identity=51.4705882352941, Blast_Score=66, Evalue=5e-12,
Organism=Homo sapiens, GI224586882, Length=68, Percent_Identity=51.4705882352941, Blast_Score=66, Evalue=5e-12,
Organism=Homo sapiens, GI34098946, Length=68, Percent_Identity=51.4705882352941, Blast_Score=66, Evalue=6e-12,
Organism=Homo sapiens, GI156415990, Length=68, Percent_Identity=50, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787107, Length=64, Percent_Identity=56.25, Blast_Score=84, Evalue=2e-18,
Organism=Escherichia coli, GI1786841, Length=61, Percent_Identity=62.2950819672131, Blast_Score=82, Evalue=5e-18,
Organism=Escherichia coli, GI2367114, Length=62, Percent_Identity=58.0645161290323, Blast_Score=77, Evalue=1e-16,
Organism=Escherichia coli, GI1789979, Length=62, Percent_Identity=56.4516129032258, Blast_Score=75, Evalue=6e-16,
Organism=Escherichia coli, GI1788126, Length=61, Percent_Identity=59.0163934426229, Blast_Score=75, Evalue=6e-16,
Organism=Escherichia coli, GI1787839, Length=62, Percent_Identity=56.4516129032258, Blast_Score=72, Evalue=6e-15,
Organism=Escherichia coli, GI1787834, Length=62, Percent_Identity=53.2258064516129, Blast_Score=71, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17533635, Length=67, Percent_Identity=47.7611940298507, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71983217, Length=65, Percent_Identity=46.1538461538462, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71983225, Length=65, Percent_Identity=46.1538461538462, Blast_Score=63, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24658520, Length=61, Percent_Identity=50.8196721311475, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24663131, Length=69, Percent_Identity=49.2753623188406, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019844
- InterPro:   IPR012156
- InterPro:   IPR011129
- InterPro:   IPR002059
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00313 CSD [H]

EC number: NA

Molecular weight: Translated: 7166; Mature: 7035

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS00352 COLD_SHOCK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASGTVKWFNDAKGFGFISQDGGGEDVFVHHTAIVAEGFRSLQEGQRVEFEVKKGPKGLQ
CCCCCEEECCCCCCCEEEECCCCCCEEEEEHHHHHHHHHHHHHCCCEEEEEECCCCCCCC
AANVRGA
CCCCCCC
>Mature Secondary Structure 
ASGTVKWFNDAKGFGFISQDGGGEDVFVHHTAIVAEGFRSLQEGQRVEFEVKKGPKGLQ
CCCCEEECCCCCCCEEEECCCCCCEEEEEHHHHHHHHHHHHHCCCEEEEEECCCCCCCC
AANVRGA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA