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The map label for this gene is ppa [H]

Identifier: 220917774

GI number: 220917774

Start: 2951780

End: 2952400

Strand: Reverse

Name: ppa [H]

Synonym: A2cp1_2675

Alternate gene names: 220917774

Gene position: 2952400-2951780 (Counterclockwise)

Preceding gene: 220917775

Following gene: 220917773

Centisome position: 58.7

GC content: 69.57

Gene sequence:

>621_bases
GTGGCCTATCACCCGTGGCACGACGTGGAGCTGCCTCGCTTCGTCGAGGATCCCATCCCCGCCATCATCGAGATCCCCAC
CGGCTCGAAGGTGAAGTACGAGCTGGACAAGAAGTCCGGGCTGCTGCTCGTGGACCGGATCCTGTTCTCCGCCGTGCACT
ACCCGGCGAACTACGGCTTCGTGCCGCGCACCTACTGCGACGACGGCGACCCGCTCGACATCCTGGTGCTCTGCTCCGAG
CAGATCCAGCCGCTCGCCATCATGCAGGCGAAGGTGATCGGCGTGATGCAGATGCGCGACGACAAGGGGCAGGACGACAA
GCTCATCGCCGTCCACGCCGACGATCCGAACTACGCCGACTACTCGGACGTCTCGGAGCTGCCGCAGCACCGCCTGCGCG
AGCTGCAGCGCTTCTTCCAGGACTACAAGGCGCTCGAGAACAAGAAGGTGCTGGTCCGCGCGCCGCAGGGGCGCTCCGAG
GCGCTCGAGGTGCTCCGCGACGCGATCCGGCTCTACGACCGGGATCGCGCGCGGCTCATGGGCACGCCGGGCCCGACCGC
GCCGGAGGCGCCCCGCGCCCGGCGACCGACCCGGGCCGGCAAGGGCGGCCGGCGCCGGTAG

Upstream 100 bases:

>100_bases
CGGCAGCCGCGTCACCCAGGCCGAGGTCCGGGAGCAGCGCTTCGCGCACGGCGCGGGCATCTGATCCGGCGCGCCCGCGC
CCCTGAAAGGAAGCACCGCA

Downstream 100 bases:

>100_bases
CGCCCGCGCCCGGCGCCCGCTCCCCCGGCCGCAGGGGAGGGGAGCGGCGCGGCAGCGCGCCCGCCCGTGTCCATCTTGGA
CGCCGGTGGGCGCGCTCCAG

Product: Inorganic diphosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MAYHPWHDVELPRFVEDPIPAIIEIPTGSKVKYELDKKSGLLLVDRILFSAVHYPANYGFVPRTYCDDGDPLDILVLCSE
QIQPLAIMQAKVIGVMQMRDDKGQDDKLIAVHADDPNYADYSDVSELPQHRLRELQRFFQDYKALENKKVLVRAPQGRSE
ALEVLRDAIRLYDRDRARLMGTPGPTAPEAPRARRPTRAGKGGRRR

Sequences:

>Translated_206_residues
MAYHPWHDVELPRFVEDPIPAIIEIPTGSKVKYELDKKSGLLLVDRILFSAVHYPANYGFVPRTYCDDGDPLDILVLCSE
QIQPLAIMQAKVIGVMQMRDDKGQDDKLIAVHADDPNYADYSDVSELPQHRLRELQRFFQDYKALENKKVLVRAPQGRSE
ALEVLRDAIRLYDRDRARLMGTPGPTAPEAPRARRPTRAGKGGRRR
>Mature_205_residues
AYHPWHDVELPRFVEDPIPAIIEIPTGSKVKYELDKKSGLLLVDRILFSAVHYPANYGFVPRTYCDDGDPLDILVLCSEQ
IQPLAIMQAKVIGVMQMRDDKGQDDKLIAVHADDPNYADYSDVSELPQHRLRELQRFFQDYKALENKKVLVRAPQGRSEA
LEVLRDAIRLYDRDRARLMGTPGPTAPEAPRARRPTRAGKGGRRR

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Homo sapiens, GI11056044, Length=171, Percent_Identity=28.6549707602339, Blast_Score=67, Evalue=9e-12,
Organism=Escherichia coli, GI1790673, Length=134, Percent_Identity=41.044776119403, Blast_Score=105, Evalue=3e-24,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 23490; Mature: 23359

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYHPWHDVELPRFVEDPIPAIIEIPTGSKVKYELDKKSGLLLVDRILFSAVHYPANYGF
CCCCCCCCCCCCHHHCCCCCEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCC
VPRTYCDDGDPLDILVLCSEQIQPLAIMQAKVIGVMQMRDDKGQDDKLIAVHADDPNYAD
CCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCC
YSDVSELPQHRLRELQRFFQDYKALENKKVLVRAPQGRSEALEVLRDAIRLYDRDRARLM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEE
GTPGPTAPEAPRARRPTRAGKGGRRR
CCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AYHPWHDVELPRFVEDPIPAIIEIPTGSKVKYELDKKSGLLLVDRILFSAVHYPANYGF
CCCCCCCCCCCHHHCCCCCEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCC
VPRTYCDDGDPLDILVLCSEQIQPLAIMQAKVIGVMQMRDDKGQDDKLIAVHADDPNYAD
CCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCC
YSDVSELPQHRLRELQRFFQDYKALENKKVLVRAPQGRSEALEVLRDAIRLYDRDRARLM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEE
GTPGPTAPEAPRARRPTRAGKGGRRR
CCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA