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The map label for this gene is cheA [H]

Identifier: 220917673

GI number: 220917673

Start: 2851771

End: 2853756

Strand: Reverse

Name: cheA [H]

Synonym: A2cp1_2574

Alternate gene names: 220917673

Gene position: 2853756-2851771 (Counterclockwise)

Preceding gene: 220917674

Following gene: 220917672

Centisome position: 56.74

GC content: 76.59

Gene sequence:

>1986_bases
ATGCGCTCCCTGGAGCAGCTGGCAGCGAGCTACCGCGAGGAGGCGGGCGAGCGGGTGGCGGAGCTGGAGGCCACCCTGCT
CGAGCTGGAGCAGGCGCCGGACGATGCCGAGCTCGTGTCGCGCGCCTTCCGCGCGCTGCACACGATCAAGGGCTCGGGCG
CGATGTTCGGCTTCGACGAGGTGGCGGCGTTCACCCACGAGCTGGAGACCGTGTTCGAGCACGTCCGCGGCGGGCGGCTC
GCCGTCACCCGCGAGCTGATCGGGCTCGCGCTCGCGGGCAAGGATCTGGTCCGCGGCATGCTGGACGGCGAGGGCGGCGC
GGACGGGCGCGAGCGCGATCGGCTCGTGGCGGCCTACCGGGCCCTCGCGCCGGACGCCGAGGCCGGGGCGCCGACGCCCG
CCGGCGGCGAGCAGGCCGACGCCGGGTGCGGCGCGGCCGGGGATGCGGCTGCGGCCCTCGGGCCGCGCACCTGGCGCATC
GCCTTCGAGCCCAACCCGGACCTGTTCGAGAACGGCACCAATCCGCTGGGGCTGCTCGACGAGCTGTCGACGCTCGGCCC
ATGCGTGGTGGTGGCCCGGACCGACGGGATCCCGCGCCTGGAGGATCTCGCGCCGGAGCGGTGCCACCTGGCCTGGGAGG
TGACCCTCACCACCGACCGCGGCGAGGACGCCATCCGCGACGTCTTCGCGTTCGTCGAGGACCGCTGCACGCTGCGCGTC
CAGGCGCTCCCCAGCGCGGAGGCCGCGCCTGCCGCGCCCAGCCCGGCCCTGGCGGCCGGGGCCGGGGAGATCGCGCGCTC
CACCGGCGGCCCGGCCCGGCCGCCCGAGGCGGCCTCCAGCGTGCGGGTCGCGGCGGCCAAGCTCGACCACCTGGTGGACC
TGGTGGGCGAGCTGGTGACCGCGCAGTCCCGGCTTGCGCGGCTCGCCGCGCAGGCGGAGGACGCGGAGCTGGGCGCGGTG
TCCGAGGGCCTGGAGCGGCTCACCGCCGACCTGCGCGACACCGCGCTCGACCTCCGCATGGTGCCCATCGGAACGGCGTT
CGGGCGCCTGCGGCGGGTGGCGCGCGACCTCGCGGCCGACCTCGGGAAGGAGATCGACCTGGTGACGGAGGGCGCCGAGA
CGGAGCTCGACAAGACCGTCATCGAGCGGCTCGCGGACCCGCTCGTGCACGTGATCCGGAACGCCTGCGATCACGGCATC
GAGACGCCCGAGGCCCGGCGCGCCGCCGGCAAGCCGCCGCGCGGGACCATCTCGCTCTCGGCCCGCCAGGCGGGCGGCAG
CGTGGTCGTCGAGGTCCGCGACGACGGCGCCGGCATCGACCCGGCGGCGGTGCGCGCGCGGGCCGAGGCCCGCGGTCTGC
TGCAGCCCGGCGCGCGCCTCGCCGAGGCGGACCTGCTCAACCTCGTGTTCCAGCCCGGATTCTCCACCGCGCGGACGGTC
ACCAGCGTCTCCGGGCGCGGCGTCGGCATGGACGTGGTGAAGCGGTCGGTCGAGGCGCTGCGCGGGACCGTGGCCCTGGA
GAGCGCGCCCGGGGCCGGCACGGCGCTGCGCATCGAGCTGCCGCTCACGCTCGCGATCATCGAGGGGCTGCTGGTGGAGG
TGGGCGGGGGCAGCTACGTGCTGCCGCTCGCGGCGGTGGAGGAGTGCGTCGGGCTCACCGCCGCGGAGGTGGAGGCGGCG
CGCGGGGCGCACCTCGCGCCGGTGCGGGGCGAGCTCGTCCCGTACCTGCGGCTCCGGGAGGTGTTCGAGGTGCGCGGCGC
GCGGCCGGACCACGAGCAGATCGCGATCGTGCGGACCGAGGCCGGGCGCTGCGGCCTGGCGGTGGACCAGGTCGCCGGCC
AGCTCCAGGCCGTCATCAAGTCGATGGGGCAGATGTTCCGCAGCGTGAAGGGGCTGTCCGGCGCCACCATCCTCGGCGAC
GGGAGCGTCGCGCCCATCCTGGACGTCGCGGCGCTGTTGAAGGAGCACGCGGCCCGCGCCGCGTGA

Upstream 100 bases:

>100_bases
GGGAAGGCCGCCGGCGCCACCGGGTGGATCGTGAAGCCGTTCACCCCCGAGCAGCTCCTCGCAGTGGCCGCGCGCCTGCT
GGGCGCCTGAGGAGGACACG

Downstream 100 bases:

>100_bases
GGCGAAGTCGACCGCAGGACGCCGGCCCCTCGGAGGGGCCGGCGCAAACGCGCCGCTCGCCCTCGCGCGCGACGCAACGG
AGACCGTATGCGCTGGTACG

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MRSLEQLAASYREEAGERVAELEATLLELEQAPDDAELVSRAFRALHTIKGSGAMFGFDEVAAFTHELETVFEHVRGGRL
AVTRELIGLALAGKDLVRGMLDGEGGADGRERDRLVAAYRALAPDAEAGAPTPAGGEQADAGCGAAGDAAAALGPRTWRI
AFEPNPDLFENGTNPLGLLDELSTLGPCVVVARTDGIPRLEDLAPERCHLAWEVTLTTDRGEDAIRDVFAFVEDRCTLRV
QALPSAEAAPAAPSPALAAGAGEIARSTGGPARPPEAASSVRVAAAKLDHLVDLVGELVTAQSRLARLAAQAEDAELGAV
SEGLERLTADLRDTALDLRMVPIGTAFGRLRRVARDLAADLGKEIDLVTEGAETELDKTVIERLADPLVHVIRNACDHGI
ETPEARRAAGKPPRGTISLSARQAGGSVVVEVRDDGAGIDPAAVRARAEARGLLQPGARLAEADLLNLVFQPGFSTARTV
TSVSGRGVGMDVVKRSVEALRGTVALESAPGAGTALRIELPLTLAIIEGLLVEVGGGSYVLPLAAVEECVGLTAAEVEAA
RGAHLAPVRGELVPYLRLREVFEVRGARPDHEQIAIVRTEAGRCGLAVDQVAGQLQAVIKSMGQMFRSVKGLSGATILGD
GSVAPILDVAALLKEHAARAA

Sequences:

>Translated_661_residues
MRSLEQLAASYREEAGERVAELEATLLELEQAPDDAELVSRAFRALHTIKGSGAMFGFDEVAAFTHELETVFEHVRGGRL
AVTRELIGLALAGKDLVRGMLDGEGGADGRERDRLVAAYRALAPDAEAGAPTPAGGEQADAGCGAAGDAAAALGPRTWRI
AFEPNPDLFENGTNPLGLLDELSTLGPCVVVARTDGIPRLEDLAPERCHLAWEVTLTTDRGEDAIRDVFAFVEDRCTLRV
QALPSAEAAPAAPSPALAAGAGEIARSTGGPARPPEAASSVRVAAAKLDHLVDLVGELVTAQSRLARLAAQAEDAELGAV
SEGLERLTADLRDTALDLRMVPIGTAFGRLRRVARDLAADLGKEIDLVTEGAETELDKTVIERLADPLVHVIRNACDHGI
ETPEARRAAGKPPRGTISLSARQAGGSVVVEVRDDGAGIDPAAVRARAEARGLLQPGARLAEADLLNLVFQPGFSTARTV
TSVSGRGVGMDVVKRSVEALRGTVALESAPGAGTALRIELPLTLAIIEGLLVEVGGGSYVLPLAAVEECVGLTAAEVEAA
RGAHLAPVRGELVPYLRLREVFEVRGARPDHEQIAIVRTEAGRCGLAVDQVAGQLQAVIKSMGQMFRSVKGLSGATILGD
GSVAPILDVAALLKEHAARAA
>Mature_661_residues
MRSLEQLAASYREEAGERVAELEATLLELEQAPDDAELVSRAFRALHTIKGSGAMFGFDEVAAFTHELETVFEHVRGGRL
AVTRELIGLALAGKDLVRGMLDGEGGADGRERDRLVAAYRALAPDAEAGAPTPAGGEQADAGCGAAGDAAAALGPRTWRI
AFEPNPDLFENGTNPLGLLDELSTLGPCVVVARTDGIPRLEDLAPERCHLAWEVTLTTDRGEDAIRDVFAFVEDRCTLRV
QALPSAEAAPAAPSPALAAGAGEIARSTGGPARPPEAASSVRVAAAKLDHLVDLVGELVTAQSRLARLAAQAEDAELGAV
SEGLERLTADLRDTALDLRMVPIGTAFGRLRRVARDLAADLGKEIDLVTEGAETELDKTVIERLADPLVHVIRNACDHGI
ETPEARRAAGKPPRGTISLSARQAGGSVVVEVRDDGAGIDPAAVRARAEARGLLQPGARLAEADLLNLVFQPGFSTARTV
TSVSGRGVGMDVVKRSVEALRGTVALESAPGAGTALRIELPLTLAIIEGLLVEVGGGSYVLPLAAVEECVGLTAAEVEAA
RGAHLAPVRGELVPYLRLREVFEVRGARPDHEQIAIVRTEAGRCGLAVDQVAGQLQAVIKSMGQMFRSVKGLSGATILGD
GSVAPILDVAALLKEHAARAA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=659, Percent_Identity=37.9362670713202, Blast_Score=372, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 68907; Mature: 68907

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSLEQLAASYREEAGERVAELEATLLELEQAPDDAELVSRAFRALHTIKGSGAMFGFDE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHH
VAAFTHELETVFEHVRGGRLAVTRELIGLALAGKDLVRGMLDGEGGADGRERDRLVAAYR
HHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
ALAPDAEAGAPTPAGGEQADAGCGAAGDAAAALGPRTWRIAFEPNPDLFENGTNPLGLLD
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCEEEEEECCCCCHHHCCCCCCHHHH
ELSTLGPCVVVARTDGIPRLEDLAPERCHLAWEVTLTTDRGEDAIRDVFAFVEDRCTLRV
HHHHCCCEEEEEECCCCCCHHHCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHCCCEEEE
QALPSAEAAPAAPSPALAAGAGEIARSTGGPARPPEAASSVRVAAAKLDHLVDLVGELVT
EECCCCCCCCCCCCCCHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AQSRLARLAAQAEDAELGAVSEGLERLTADLRDTALDLRMVPIGTAFGRLRRVARDLAAD
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHH
LGKEIDLVTEGAETELDKTVIERLADPLVHVIRNACDHGIETPEARRAAGKPPRGTISLS
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEE
ARQAGGSVVVEVRDDGAGIDPAAVRARAEARGLLQPGARLAEADLLNLVFQPGFSTARTV
EECCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHH
TSVSGRGVGMDVVKRSVEALRGTVALESAPGAGTALRIELPLTLAIIEGLLVEVGGGSYV
HHCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCCEEEEECCHHHHHHHHHHEEECCCCEE
LPLAAVEECVGLTAAEVEAARGAHLAPVRGELVPYLRLREVFEVRGARPDHEQIAIVRTE
EHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEC
AGRCGLAVDQVAGQLQAVIKSMGQMFRSVKGLSGATILGDGSVAPILDVAALLKEHAARA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHCC
A
C
>Mature Secondary Structure
MRSLEQLAASYREEAGERVAELEATLLELEQAPDDAELVSRAFRALHTIKGSGAMFGFDE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHH
VAAFTHELETVFEHVRGGRLAVTRELIGLALAGKDLVRGMLDGEGGADGRERDRLVAAYR
HHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
ALAPDAEAGAPTPAGGEQADAGCGAAGDAAAALGPRTWRIAFEPNPDLFENGTNPLGLLD
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCEEEEEECCCCCHHHCCCCCCHHHH
ELSTLGPCVVVARTDGIPRLEDLAPERCHLAWEVTLTTDRGEDAIRDVFAFVEDRCTLRV
HHHHCCCEEEEEECCCCCCHHHCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHCCCEEEE
QALPSAEAAPAAPSPALAAGAGEIARSTGGPARPPEAASSVRVAAAKLDHLVDLVGELVT
EECCCCCCCCCCCCCCHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AQSRLARLAAQAEDAELGAVSEGLERLTADLRDTALDLRMVPIGTAFGRLRRVARDLAAD
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHH
LGKEIDLVTEGAETELDKTVIERLADPLVHVIRNACDHGIETPEARRAAGKPPRGTISLS
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEE
ARQAGGSVVVEVRDDGAGIDPAAVRARAEARGLLQPGARLAEADLLNLVFQPGFSTARTV
EECCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHH
TSVSGRGVGMDVVKRSVEALRGTVALESAPGAGTALRIELPLTLAIIEGLLVEVGGGSYV
HHCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCCEEEEECCHHHHHHHHHHEEECCCCEE
LPLAAVEECVGLTAAEVEAARGAHLAPVRGELVPYLRLREVFEVRGARPDHEQIAIVRTE
EHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEC
AGRCGLAVDQVAGQLQAVIKSMGQMFRSVKGLSGATILGDGSVAPILDVAALLKEHAARA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7623670; 11481430 [H]