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The map label for this gene is cheW [H]

Identifier: 220917671

GI number: 220917671

Start: 2849235

End: 2849792

Strand: Reverse

Name: cheW [H]

Synonym: A2cp1_2572

Alternate gene names: 220917671

Gene position: 2849792-2849235 (Counterclockwise)

Preceding gene: 220917672

Following gene: 220917670

Centisome position: 56.66

GC content: 72.22

Gene sequence:

>558_bases
ATGGACGAGTCGGCCTCGACCCGAAGCCAGCAGTACCTGACCTTCACGCTCGACGGCGAGCACTACGCCGTCGAGATCGA
GCGGGTGCGTGAGGTGCTCGAGTTCACCGGGGTGAACAAGGTGCCGCGCACCCCCGACTTCCTGCGCGGCATGATCAACC
TTCGGGGAGACATCGTCCCGGTGGTGGACCTGCGCCTGAAGCTCGGCCTCTCCCCCACGGAGCGGACGATCGACACCTGC
GTCGTCATCACCGAGGTCACGGCCGACGGCGAGCCCCTCGTGCTCGGCGCCCTGGCCGACTCGGTCCAGGAGGTGATCGA
GCTCGATCCTGCCGCCATCGCGCCGCCGCCGCGCATGGGCGCGCGGGTCGACACCGCCTTCATCCGCGGGATGGGCCGGC
GCGAGGACCAGTTCCTCGTCATCCTCGACATCGAGCGGGTGCTCGCGGAGGACGGGCTGCGCGCGCTGACGGAGCCGCTG
GGCGCGGGCGTCCCTCCGGGCGCGGCGCCGGACGGCGCCGGGGTGGAGCGGGTGGGCGATGCTGGGCTCGCGGGCTGA

Upstream 100 bases:

>100_bases
GCGCCGTCCGAGGCCGGCGTCCGCATCGAGCTCGCCGAGGCCCCGGAGCCGGAGCCGGGCTACCAGGCCTACTGAGCGCC
CCGCCCGACCGGAGAACGCC

Downstream 100 bases:

>100_bases
TCGGCGCGGGGCGGACCGCGGCCCGACGGGCCCGGCGGCGAGCCGGCTCGCCGGGCCGCCCGCGCTCTCGCCGCGGGACT
TCGCGCGCCTGAGCGCGTTC

Product: chemotaxis protein CheW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MDESASTRSQQYLTFTLDGEHYAVEIERVREVLEFTGVNKVPRTPDFLRGMINLRGDIVPVVDLRLKLGLSPTERTIDTC
VVITEVTADGEPLVLGALADSVQEVIELDPAAIAPPPRMGARVDTAFIRGMGRREDQFLVILDIERVLAEDGLRALTEPL
GAGVPPGAAPDGAGVERVGDAGLAG

Sequences:

>Translated_185_residues
MDESASTRSQQYLTFTLDGEHYAVEIERVREVLEFTGVNKVPRTPDFLRGMINLRGDIVPVVDLRLKLGLSPTERTIDTC
VVITEVTADGEPLVLGALADSVQEVIELDPAAIAPPPRMGARVDTAFIRGMGRREDQFLVILDIERVLAEDGLRALTEPL
GAGVPPGAAPDGAGVERVGDAGLAG
>Mature_185_residues
MDESASTRSQQYLTFTLDGEHYAVEIERVREVLEFTGVNKVPRTPDFLRGMINLRGDIVPVVDLRLKLGLSPTERTIDTC
VVITEVTADGEPLVLGALADSVQEVIELDPAAIAPPPRMGARVDTAFIRGMGRREDQFLVILDIERVLAEDGLRALTEPL
GAGVPPGAAPDGAGVERVGDAGLAG

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=147, Percent_Identity=32.6530612244898, Blast_Score=93, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 19786; Mature: 19786

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDESASTRSQQYLTFTLDGEHYAVEIERVREVLEFTGVNKVPRTPDFLRGMINLRGDIVP
CCCCCCCCCCEEEEEEECCCEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEE
VVDLRLKLGLSPTERTIDTCVVITEVTADGEPLVLGALADSVQEVIELDPAAIAPPPRMG
EEEEEEECCCCCCHHHHCEEEEEEEECCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCC
ARVDTAFIRGMGRREDQFLVILDIERVLAEDGLRALTEPLGAGVPPGAAPDGAGVERVGD
CHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCC
AGLAG
CCCCC
>Mature Secondary Structure
MDESASTRSQQYLTFTLDGEHYAVEIERVREVLEFTGVNKVPRTPDFLRGMINLRGDIVP
CCCCCCCCCCEEEEEEECCCEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEE
VVDLRLKLGLSPTERTIDTCVVITEVTADGEPLVLGALADSVQEVIELDPAAIAPPPRMG
EEEEEEECCCCCCHHHHCEEEEEEEECCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCC
ARVDTAFIRGMGRREDQFLVILDIERVLAEDGLRALTEPLGAGVPPGAAPDGAGVERVGD
CHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCC
AGLAG
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]