Click here to switch to the map view.

The map label for this gene is argS

Identifier: 220917531

GI number: 220917531

Start: 2688300

End: 2690096

Strand: Reverse

Name: argS

Synonym: A2cp1_2431

Alternate gene names: 220917531

Gene position: 2690096-2688300 (Counterclockwise)

Preceding gene: 220917532

Following gene: 220917530

Centisome position: 53.49

GC content: 72.01

Gene sequence:

>1797_bases
ATGGTCCGTGATCGCGTCATCGAACTCTTCCGCAAGGCGCTCGCCCAGGGCGCCGACGACGGGCGCTGGCCGGCGGCGGG
CGCCGGCTTCTCGGTGGAGGCGCCGCGCGACCCGAAGCACGGCGACTTCGCGGTGAACGCCGCCATGGTGCTGGCGAAGC
AGGCGGGCAGGCCGCCGCGCGAGCTGGCGCAGGCGATCGTCGAGGCGGTGCGCGCGGCCGACACCGCCGGCGACCTGGCC
GGCCTGGAGATCGCCGGCCCCGGCTTCATCAACGTGCGGCTCTCCCCGGACCTGTGGCTGCGCACGCTCGCGCGCGCGGT
CGCGGAGGGCCCGGACTACGGCCGGACCGCGGTGGGGCAGGGGAAGAAGGTCATCGTCGAGTACGTGTCGGCCAACCCGA
CCGGCCCGATGCACGTCGGGCACGGGCGCAACGCGGTCGTGGGCGACGGCGTCCAGGGCCTGCTGCGCTGGGCCGGCTTC
GACGTCACCCGCGAGTACTACGTCAACGACTACGGCGCGCAGGTGCAGACGCTGGCGCGCTCGGTCCACCTCCGCTACCA
GGAGCTGCACGGGCGGACCGTGACCATGCCGCCCAAGAGCTATCCGGGCGAGTACGTGAAGGACATCGCCGCCGGCCTGA
AGGCCGAGTACGGGGCGAGGTTCCTGGACGCGCCCGAGGCCGAGTGGCTCACGCTGTTCCGCGACCACTCGGTCCAGCAC
GTGCTCGGGATGATCCGCGGGGACCTCGCCGCGGTGAACATCTCGTTCGACCGCTGGTCGTCGGAGAAGGCGCTCTACGA
GTCGGGCACGGTGGACCGCTTCCTCCGCTTCCTGGAGGAGAAGGACCTCGTCTACGTCGGCAAGCTGCCGCCGCCGAAGT
CGAAGAAGGGGCAGCCGCCGCCGCAGCCGCAGCCCGACGAGGAGGGCGTGACCGCGGCCGAGGACCTCACGCTGTTCCGC
TCGTCGGCGTACGGCGACGAGGTGGACCGGCCGGTGAAGAAGGCGGACGGGACGCCCACCTACTTCTGCGCGGACATCGC
GTACCACTGGGACAAGCGCCAGCGCGCGGACGCGCTGGTGGACGTGCTCGGCGCCGACCACGGCGGCTACGTGCCGCGGC
TCGAGGCGGCGATGGAGGCGCTGGGCGCCTCGCGCAAGGACCTGCACGTCGTGCTGATCCAGATGGTCAGCCTGATGCGC
GGGGGCGAGTCGGTGAAGATGTCGAAGCGCGCCGGCACGCTCGTGTCGCTGCGGGAGGTGGTCGACGAGGTGGGGCGCGA
CGCGACCCGCTTCATCTTCCTCACCCGGCGCTCCGACGCGCCGCTCGACTTCGACGTCGAGCTCGCCAAGCGGCAGACGC
TCGACAACCCGGTCTTCTACGTCCAGTACGGGCACGCGCGCCTGGCGGCCATCTTCCAGAAGGCGCGCGAGGCCGGGCAC
GCGGTGCCCGACTTCGACCTCGAGGCCGCGCGGACGCTCGCCTCGCCGGAGGAGCAGGACCTCATCCGCCGCATCGCCGC
GTTCCCGGACATGCTCGCCGCCGCCGCGCTCGCCTACGAGCCGCACCGGGTGGCGTTCTACCTCCAGGAGACCATCGCCG
CGTTCCACTCCTGGTACACGCAGGGGAAGAAGAGCGGCGAGAAGGTCATCGGGCCCGACCCGGTCAAGACCGCGGCGCGC
CTGTTCCTGTGCCGCGCCCTGAAGCAGGTGCTCGCGAACGGCCTGGCGGTCCTGGGCGTCTCCGCGCCGGATCGGATGGA
GAGTCCGGAAACTCGCGATATCGCGGACGACGTCTAG

Upstream 100 bases:

>100_bases
CGCTGCGGCGCGTTCGACGCCTATCCCTGAGCAAGCTCCGGCCCGCGCGCGGCCCGGCGCTTGCTTCCGGCGCGCGCCCC
CGGTAGAGAGACCCCTTCCT

Downstream 100 bases:

>100_bases
AATCCAGGCTGCCGCGGTTCGCGCCCCCGGTCCTCGCGGCGCGCGCCCGTCTCCGCGGCGGGGTGACGTCCATGCGCGAA
GAGAACGTCCGGAGCCGTGA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 598; Mature: 598

Protein sequence:

>598_residues
MVRDRVIELFRKALAQGADDGRWPAAGAGFSVEAPRDPKHGDFAVNAAMVLAKQAGRPPRELAQAIVEAVRAADTAGDLA
GLEIAGPGFINVRLSPDLWLRTLARAVAEGPDYGRTAVGQGKKVIVEYVSANPTGPMHVGHGRNAVVGDGVQGLLRWAGF
DVTREYYVNDYGAQVQTLARSVHLRYQELHGRTVTMPPKSYPGEYVKDIAAGLKAEYGARFLDAPEAEWLTLFRDHSVQH
VLGMIRGDLAAVNISFDRWSSEKALYESGTVDRFLRFLEEKDLVYVGKLPPPKSKKGQPPPQPQPDEEGVTAAEDLTLFR
SSAYGDEVDRPVKKADGTPTYFCADIAYHWDKRQRADALVDVLGADHGGYVPRLEAAMEALGASRKDLHVVLIQMVSLMR
GGESVKMSKRAGTLVSLREVVDEVGRDATRFIFLTRRSDAPLDFDVELAKRQTLDNPVFYVQYGHARLAAIFQKAREAGH
AVPDFDLEAARTLASPEEQDLIRRIAAFPDMLAAAALAYEPHRVAFYLQETIAAFHSWYTQGKKSGEKVIGPDPVKTAAR
LFLCRALKQVLANGLAVLGVSAPDRMESPETRDIADDV

Sequences:

>Translated_598_residues
MVRDRVIELFRKALAQGADDGRWPAAGAGFSVEAPRDPKHGDFAVNAAMVLAKQAGRPPRELAQAIVEAVRAADTAGDLA
GLEIAGPGFINVRLSPDLWLRTLARAVAEGPDYGRTAVGQGKKVIVEYVSANPTGPMHVGHGRNAVVGDGVQGLLRWAGF
DVTREYYVNDYGAQVQTLARSVHLRYQELHGRTVTMPPKSYPGEYVKDIAAGLKAEYGARFLDAPEAEWLTLFRDHSVQH
VLGMIRGDLAAVNISFDRWSSEKALYESGTVDRFLRFLEEKDLVYVGKLPPPKSKKGQPPPQPQPDEEGVTAAEDLTLFR
SSAYGDEVDRPVKKADGTPTYFCADIAYHWDKRQRADALVDVLGADHGGYVPRLEAAMEALGASRKDLHVVLIQMVSLMR
GGESVKMSKRAGTLVSLREVVDEVGRDATRFIFLTRRSDAPLDFDVELAKRQTLDNPVFYVQYGHARLAAIFQKAREAGH
AVPDFDLEAARTLASPEEQDLIRRIAAFPDMLAAAALAYEPHRVAFYLQETIAAFHSWYTQGKKSGEKVIGPDPVKTAAR
LFLCRALKQVLANGLAVLGVSAPDRMESPETRDIADDV
>Mature_598_residues
MVRDRVIELFRKALAQGADDGRWPAAGAGFSVEAPRDPKHGDFAVNAAMVLAKQAGRPPRELAQAIVEAVRAADTAGDLA
GLEIAGPGFINVRLSPDLWLRTLARAVAEGPDYGRTAVGQGKKVIVEYVSANPTGPMHVGHGRNAVVGDGVQGLLRWAGF
DVTREYYVNDYGAQVQTLARSVHLRYQELHGRTVTMPPKSYPGEYVKDIAAGLKAEYGARFLDAPEAEWLTLFRDHSVQH
VLGMIRGDLAAVNISFDRWSSEKALYESGTVDRFLRFLEEKDLVYVGKLPPPKSKKGQPPPQPQPDEEGVTAAEDLTLFR
SSAYGDEVDRPVKKADGTPTYFCADIAYHWDKRQRADALVDVLGADHGGYVPRLEAAMEALGASRKDLHVVLIQMVSLMR
GGESVKMSKRAGTLVSLREVVDEVGRDATRFIFLTRRSDAPLDFDVELAKRQTLDNPVFYVQYGHARLAAIFQKAREAGH
AVPDFDLEAARTLASPEEQDLIRRIAAFPDMLAAAALAYEPHRVAFYLQETIAAFHSWYTQGKKSGEKVIGPDPVKTAAR
LFLCRALKQVLANGLAVLGVSAPDRMESPETRDIADDV

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=152, Percent_Identity=35.5263157894737, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI1788184, Length=153, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71985061, Length=639, Percent_Identity=22.3787167449139, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71985068, Length=606, Percent_Identity=22.1122112211221, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI18859963, Length=598, Percent_Identity=22.5752508361204, Blast_Score=90, Evalue=5e-18,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_ANAD2 (B8JBE2)

Other databases:

- EMBL:   CP001359
- RefSeq:   YP_002492835.1
- ProteinModelPortal:   B8JBE2
- GeneID:   7300091
- GenomeReviews:   CP001359_GR
- KEGG:   acp:A2cp1_2431
- HOGENOM:   HBG695395
- ProtClustDB:   PRK01611
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 65536; Mature: 65536

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRDRVIELFRKALAQGADDGRWPAAGAGFSVEAPRDPKHGDFAVNAAMVLAKQAGRPPR
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHH
ELAQAIVEAVRAADTAGDLAGLEIAGPGFINVRLSPDLWLRTLARAVAEGPDYGRTAVGQ
HHHHHHHHHHHHHCCCCCCCCEEECCCCEEEEEECHHHHHHHHHHHHHCCCCCCCHHHCC
GKKVIVEYVSANPTGPMHVGHGRNAVVGDGVQGLLRWAGFDVTREYYVNDYGAQVQTLAR
CCEEEEEEECCCCCCCEEECCCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHH
SVHLRYQELHGRTVTMPPKSYPGEYVKDIAAGLKAEYGARFLDAPEAEWLTLFRDHSVQH
HHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHCCHHH
VLGMIRGDLAAVNISFDRWSSEKALYESGTVDRFLRFLEEKDLVYVGKLPPPKSKKGQPP
HHHHHHCCEEEEEEEHHCCCCCHHHHHCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCC
PQPQPDEEGVTAAEDLTLFRSSAYGDEVDRPVKKADGTPTYFCADIAYHWDKRQRADALV
CCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHH
DVLGADHGGYVPRLEAAMEALGASRKDLHVVLIQMVSLMRGGESVKMSKRAGTLVSLREV
HHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHH
VDEVGRDATRFIFLTRRSDAPLDFDVELAKRQTLDNPVFYVQYGHARLAAIFQKAREAGH
HHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHCC
AVPDFDLEAARTLASPEEQDLIRRIAAFPDMLAAAALAYEPHRVAFYLQETIAAFHSWYT
CCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
QGKKSGEKVIGPDPVKTAARLFLCRALKQVLANGLAVLGVSAPDRMESPETRDIADDV
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVRDRVIELFRKALAQGADDGRWPAAGAGFSVEAPRDPKHGDFAVNAAMVLAKQAGRPPR
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHH
ELAQAIVEAVRAADTAGDLAGLEIAGPGFINVRLSPDLWLRTLARAVAEGPDYGRTAVGQ
HHHHHHHHHHHHHCCCCCCCCEEECCCCEEEEEECHHHHHHHHHHHHHCCCCCCCHHHCC
GKKVIVEYVSANPTGPMHVGHGRNAVVGDGVQGLLRWAGFDVTREYYVNDYGAQVQTLAR
CCEEEEEEECCCCCCCEEECCCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHH
SVHLRYQELHGRTVTMPPKSYPGEYVKDIAAGLKAEYGARFLDAPEAEWLTLFRDHSVQH
HHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHCCHHH
VLGMIRGDLAAVNISFDRWSSEKALYESGTVDRFLRFLEEKDLVYVGKLPPPKSKKGQPP
HHHHHHCCEEEEEEEHHCCCCCHHHHHCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCC
PQPQPDEEGVTAAEDLTLFRSSAYGDEVDRPVKKADGTPTYFCADIAYHWDKRQRADALV
CCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHH
DVLGADHGGYVPRLEAAMEALGASRKDLHVVLIQMVSLMRGGESVKMSKRAGTLVSLREV
HHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHH
VDEVGRDATRFIFLTRRSDAPLDFDVELAKRQTLDNPVFYVQYGHARLAAIFQKAREAGH
HHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHCC
AVPDFDLEAARTLASPEEQDLIRRIAAFPDMLAAAALAYEPHRVAFYLQETIAAFHSWYT
CCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
QGKKSGEKVIGPDPVKTAARLFLCRALKQVLANGLAVLGVSAPDRMESPETRDIADDV
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA